Unique triterpenoid of jujube root protects cisplatin-induced damage in kidney epithelial LLC-PK1 cells via autophagy regulation
Dahae Lee
Kyo Bin Kang
Hyun Woo Kim
Jung Sik Park
Gwi Seo Hwang
Ki Sung Kang
Sungyoul Choi
Noriko Yamabe
Ki Hyun Kim
Nutrients, 2020
Kyo Bin Kang
Kang Kyo Bin
ORCID: 0000-0003-3290-1017
Email: kbkang@sookmyung.ac.kr
Prediction of tyrosinase inhibitory activities of Morus alba root bark extracts from HPLC fingerprints
10.1016/j.microc.2013.08.012
Anti-Influenza Activity of Betulinic Acid from Zizyphus jujuba on Influenza A/PR/8 Virus
10.4062/biomolther.2015.019
Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
10.1016/j.phytochem.2015.09.001
Identification of ginsenoside markers from dry purified extract of Panax ginseng by a dereplication approach and UPLC–QTOF/MS analysis
10.1016/j.jpba.2015.02.034
Antiplasmodial activity, cytotoxicity and structure-activity relationship study of cyclopeptide alkaloids
10.3390/molecules22020224
Catechin-Bound Ceanothane-Type Triterpenoid Derivatives from the Roots of Zizyphus jujuba
10.1021/acs.jnatprod.6b01103
Ceanothane- and lupane-type triterpene esters from the roots of Hovenia dulcis and their antiproliferative activity on HSC-T6 cells
10.1016/j.phytochem.2017.06.014
Cytotoxic Ceanothane- and Lupane-Type Triterpenoids from the Roots of Ziziphus jujuba
10.1021/acs.jnatprod.6b00525
UHPLC-ESI-qTOF-MS analysis of cyclopeptide alkaloids in the seeds of Ziziphus jujuba var. Spinosa
10.5478/MSL.2016.7.2.45
Acylphloroglucinolated Catechin and Phenylethyl Isocoumarin Derivatives from Agrimonia pilosa
10.1021/acs.jnatprod.6b00566
Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells
10.1016/j.jep.2016.08.039
Combined Application of UHPLC-QTOF/MS, HPLC-ELSD and 1H–NMR Spectroscopy for Quality Assessment of DA-9801, A Standardised Dioscorea Extract
10.1002/pca.2659
Argininosecologanin, a secoiridoid-derived guanidine alkaloid from the roots of Lonicera insularis
10.1080/14786419.2017.1361953
C-Methylated Flavonoid Glycosides from Pentarhizidium orientale Rhizomes and Their Inhibitory Effects on the H1N1 Influenza Virus
10.1021/acs.jnatprod.7b00677
Berchemiosides A–C, 2-Acetoxy-ω-phenylpentaene Fatty Acid Triglycosides from the Unripe Fruits of Berchemia berchemiifolia
10.1021/acs.jnatprod.7b00602
Rhamnellosides A and B, ω-phenylpentaene fatty acid amide diglycosides from the fruits of rhamnella franguloides
10.3390/molecules23040752
Identification of candidate UDP-glycosyltransferases involved in protopanaxadiol-type ginsenoside biosynthesis in Panax ginseng
10.1038/s41598-018-30262-7
Genome and evolution of the shade-requiring medicinal herb Panax ginseng
10.1111/pbi.12926
Simultaneous Determination and Stability Test of Two Phthalic Anhydride Derivatives, Senkyunolide A and Z-Ligustilide, in the Water Extract of Cnidium Rhizome from Different Geographical Regions and Species Using HPLC-UVD Analysis
10.1002/bkcs.11471
Chemical and genomic diversity of six Lonicera species occurring in Korea
10.1016/j.phytochem.2018.07.012
Targeted Isolation of Neuroprotective Dicoumaroyl Neolignans and Lignans from Sageretia theezans Using in Silico Molecular Network Annotation Propagation-Based Dereplication
10.1021/acs.jnatprod.8b00292
The complete chloroplast genome sequence of Korean Lonicera japonica and intra-species diversity
10.1080/23802359.2018.1502637
Classficiation of Bupleuri Radix according to Geographical Origins using Near Infrared Spectroscopy (NIRS) Combined with Supervised Pattern Recognition
10.20307/nps.2018.24.3.164
Multiple Targets of 3-Dehydroxyceanothetric Acid 2-Methyl Ester to Protect Against Cisplatin-Induced Cytotoxicity in Kidney Epithelial LLC-PK1 Cells
10.3390/molecules24050878
Comprehensive mass spectrometry-guided phenotyping of plant specialized metabolites reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae
10.1111/tpj.14292
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages
10.1016/j.foodchem.2019.125290
Molecular Networking Reveals the Chemical Diversity of Selaginellin Derivatives, Natural Phosphodiesterase-4 Inhibitors from Selaginella tamariscina
10.1021/acs.jnatprod.9b00049
Identification and semi-synthesis of 3-O-protocatechuoylceanothic acid, a novel and natural GPR120 agonist †
10.3390/molecules24193487
Reproducible molecular networking of untargeted mass spectrometry data using GNPS
10.1038/s41596-020-0317-5
Assessing specialized metabolite diversity of Alnus species by a digitized LC–MS/MS data analysis workflow
10.1016/j.phytochem.2020.112292
Unique triterpenoid of jujube root protects cisplatin-induced damage in kidney epithelial LLC-PK1 cells via autophagy regulation
10.3390/nu12030677
Molnetenhancer: Enhanced molecular networks by integrating metabolome mining and annotation tools
10.3390/metabo9070144
Combined MS/MS-NMR Annotation Guided Discovery of Iris lactea var. chinensis Seed as a Source of Viral Neuraminidase Inhibitory Polyphenols
10.3390/molecules25153383
Feature-based molecular networking in the GNPS analysis environment
10.1038/s41592-020-0933-6
A Metabolic Choreography of Maize Plants Treated with a Humic Substance-Based Biostimulant under Normal and Starved Conditions
10.3390/metabo11060403
Chemical and Biological Profiles of Dendrobium in Two Different Species, Their Hybrid, and Gamma-Irradiated Mutant Lines of the Hybrid Based on LC-QToF MS and Cytotoxicity Analysis
10.3390/plants10071376
Ki Hyun Kim
Kim Ki Hyun
ORCID: 0000-0002-5285-9138
Bioactivity-guided isolation of antioxidant triterpenoids from Betula platyphylla var. japonica bark
10.1016/j.bioorg.2016.04.001
Protective effect of Korean Red Ginseng against FK506-induced damage in LLC-PK1 cells
10.1016/j.jgr.2016.05.002
Inhibitory effect of Sphagnum palustre extract and its bioactive compounds on aromatase activity
10.3329/bjp.v11i3.26776
Pharbilignan C induces apoptosis through a mitochondria-mediated intrinsic pathway in human breast cancer cells
10.1016/j.bmcl.2016.08.054
A new rearranged eudesmane sesquiterpene and bioactive sesquiterpenes from the twigs of Lindera glauca (Sieb. et Zucc.) Blume
10.1007/s12272-016-0838-1
Dynamic metabolic exchange governs a marine algal-bacterial interaction
10.7554/eLife.17473
Termisoflavones A–C, Isoflavonoid Glycosides from Termite-Associated Streptomyces sp. RB1
10.1021/acs.jnatprod.6b00738
Protective effect of ginsenoside Rb1 against tacrolimus-induced apoptosis in renal proximal tubular LLC-PK1 cells
10.1016/j.jgr.2016.12.013
Macrotermycins A–D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39
10.1021/acs.orglett.6b03831
Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides
10.1021/acs.orglett.7b00545
Beneficial effects of Panax ginseng for the treatment and prevention of neurodegenerative diseases: past findings and future directions
10.1016/j.jgr.2017.03.011
Total Synthesis of Isohericerin, Isohericenone, and Erinacerin A: Development of a Copper-Catalyzed Methylboronation of Terminal Alkynes
10.1021/acs.joc.7b00920
Chemical constituents from the fruits of Citrus unshiu and their inhibitory effects on acetylcholinesterase
10.20450/mjcce.2017.1139
Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c-Fos Degradation
10.1021/acs.jnatprod.7b00433
Vulpinic acid contributes to the cytotoxicity of Pulveroboletus ravenelii to human cancer cells by inducing apoptosis
10.1039/C7RA05059C
Chemical constituents from the rare mushroom Calvatia nipponica inhibit the promotion of angiogenesis in HUVECs
10.1016/j.bmcl.2017.07.036
Anti-Inflammatory Phenolic Metabolites from the Edible Fungus Phellinus baumii in LPS-Stimulated RAW264.7 Cells
10.3390/molecules22101583
C-Methylated Flavonoid Glycosides from Pentarhizidium orientale Rhizomes and Their Inhibitory Effects on the H1N1 Influenza Virus
10.1021/acs.jnatprod.7b00677
Bioactivity-guided isolation and chemical characterization of antiproliferative constituents from morel mushroom (Morchella esculenta) in human lung adenocarcinoma cells
10.1016/j.jff.2017.11.012
Chemical Characterization of a Renoprotective Metabolite from Termite-Associated Streptomyces sp. RB1 against Cisplatin-Induced Cytotoxicity
10.3390/ijms19010174
Antigastritis effects of Armillariella tabescens (Scop.) Sing. and the identification of its anti-inflammatory metabolites
10.1111/jphp.12871
7α,15-Dihydroxydehydroabietic acid from Pinus koraiensis inhibits the promotion of angiogenesis through downregulation of VEGF, p-Akt and p-ERK in HUVECs
10.1016/j.bmcl.2018.02.014
Chemical Characterization of Novel Natural Products from the Roots of Asian Rice (Oryza sativa) that Control Adipocyte and Osteoblast Differentiation
10.1021/acs.jafc.7b05030
Beneficial Effects of Bioactive Compounds in Mulberry Fruits against Cisplatin-Induced Nephrotoxicity
10.3390/ijms19041117
Lignan Glycosides and Flavonoid Glycosides from the Aerial Portion of Lespedeza cuneata and Their Biological Evaluations
10.3390/molecules23081920
Bioactivity evaluations of betulin identified from the bark of Betula platyphylla var. japonica for cancer therapy
10.1007/s12272-018-1064-9
The effects of phenolic glycosides from Betula platyphylla var. japonica on adipocyte differentiation and mature adipocyte metabolism
10.1080/14756366.2018.1491846
Cytotoxic Constituents from the Sclerotia of Poria cocos against Human Lung Adenocarcinoma Cells by Inducing Mitochondrial Apoptosis
10.3390/cells7090116
Chemical Identification of Isoflavonoids from a Termite-Associated Streptomyces sp. RB1 and Their Neuroprotective Effects in Murine Hippocampal HT22 Cell Line
10.3390/ijms19092640
The Inhibitory Effects of Cyclodepsipeptides from the Entomopathogenic Fungus Beauveria bassiana on Myofibroblast Differentiation in A549 Alveolar Epithelial Cells
10.3390/molecules23102568
Biological Evaluation of a New Lignan from the Roots of Rice (Oryza sativa )
10.1002/cbdv.201800333
Tirucallane Triterpenoids from the Stems and Stem Bark of Cornus walteri that Control Adipocyte and Osteoblast Differentiations
10.3390/molecules23112732
Highly Sensitive, Simple, and Cost- and Time-Effective Method to Determine the Absolute Configuration of a Secondary Alcohol Using Competing Enantioselective Acylation Coupled with LC/MS
10.1021/acs.analchem.8b03385
Beauvetetraones A–C, phomaligadione-derived polyketide dimers from the entomopathogenic fungus, Beauveria bassiana
10.1039/C8QO01009A
Macrocyclic Trichothecene Mycotoxins from a Deadly Poisonous Mushroom, Podostroma cornu-damae
10.1021/acs.jnatprod.8b00823
Natalenamides A–C, Cyclic Tripeptides from the Termite-Associated Actinomadura sp. RB99
10.3390/molecules23113003
Cover Picture: Biological Evaluation of a New Lignan from the Roots of Rice (Oryza sativa ) (C&B 11/2018)
10.1002/cbdv.201800537
GABA-modulating bacteria of the human gut microbiota
10.1038/s41564-018-0307-3
Spirocyclic cladosporicin A and cladosporiumins I and J from a Hydractinia-associated Cladosporium sphaerospermum SW67
10.1039/C8QO01104D
Isoamericanoic Acid B from Acer tegmentosum as a Potential Phytoestrogen
10.3390/nu10121915
Isolation of maltol derivatives from Stellera chamaejasme and the anti-atopic properties of maltol on skin lesions in DNCB-stimulated mice
10.1039/C8RA09743G
Cytotoxic Withanolides from the Roots of Indian Ginseng (Withania somnifera)
10.1021/acs.jnatprod.8b00665
Multiple Targets of 3-Dehydroxyceanothetric Acid 2-Methyl Ester to Protect Against Cisplatin-Induced Cytotoxicity in Kidney Epithelial LLC-PK1 Cells
10.3390/molecules24050878
Bioactivity-based analysis and chemical characterization of cytotoxic compounds from a poisonous mushroom, Amanita spissacea, in human lung cancer cells in vitro
10.1080/14786419.2019.1586699
Fridamycin A, a Microbial Natural Product, Stimulates Glucose Uptake without Inducing Adipogenesis
10.3390/nu11040765
Comprehensive Investigation of the Effects of Brewing Conditions in Sample Preparation of Green Tea Infusions
10.3390/molecules24091735
Betulinic Acid Suppresses Ovarian Cancer Cell Proliferation through Induction of Apoptosis
10.3390/biom9070257
Procyanidin B2 3″-O-gallate Isolated from Reynoutria elliptica Prevents Glutamate-Induced HT22 Cell Death by Blocking the Accumulation of Intracellular Reactive Oxygen Species
10.3390/biom9090412
Chemical Composition and Antimicrobial Activity of Essential Oils from the Aerial Parts of Pinus eldarica Grown in Northwestern Iran
10.3390/molecules24173203
Bioactive compounds from the seeds of Amomum tsaoko Crevost et Lemaire, a Chinese spice as inhibitors of sphingosine kinases, SPHK1/2
10.1039/C9RA07988B
Hybrid Polyketides from a Hydractinia-Associated Cladosporium sphaerospermum SW67 and Their Putative Biosynthetic Origin
10.3390/md17110606
(3β,16α)-3,16-Dihydroxypregn-5-en-20-one from the Twigs of Euonymus alatus (Thunb.) Sieb. Exerts Anti-Inflammatory Effects in LPS-Stimulated RAW-264.7 Macrophages
10.3390/molecules24213848
Pantheric Acids A–C from a Poisonous Mushroom, Amanita pantherina, Promote Lipid Accumulation in Adipocytes
10.1021/acs.jnatprod.9b00782
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10.20944/preprints201911.0171.v1
Lobatamunsolides A–C, Norlignans from the Roots of Pueraria lobata and their Nitric Oxide Inhibitory Activities in Macrophages
10.3390/biom9120755
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10.3390/plants8120527
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10.3390/jcm9010059
(–)-Catechin-7-O-β-d-Apiofuranoside Inhibits Hepatic Stellate Cell Activation by Suppressing the STAT3 Signaling Pathway
10.3390/cells9010030
Absolute Configuration and Corrected NMR Assignment of 17-Hydroxycyclooctatin, a Fused 5–8–5 Tricyclic Diterpene
10.1021/acs.jnatprod.9b00837
Trichothecene and tremulane sesquiterpenes from a hallucinogenic mushroom Gymnopilus junonius and their cytotoxicity
10.1007/s12272-020-01213-6
Benzyl salicylate from the stems and stem barks of Cornus walteri as a nephroprotective agent against cisplatin-induced apoptotic cell death in LLC-PK1 cells
10.1039/C9RA07009E
Inhibitory Effect of 1,5-Dimethyl Citrate from Sea Buckthorn (Hippophae rhamnoides) on Lipopolysaccharide-Induced Inflammatory Response in RAW 264.7 Mouse Macrophages
10.3390/foods9030269
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10.1021/acs.jnatprod.9b01120
Cumulative Effects of Constituents from the Mushroom Calvatia nipponica on the Contractility of Penile Corpus Cavernosum Smooth Muscle
10.1080/12298093.2020.1732008
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Unique Triterpenoid of Jujube Root Protects Cisplatin-induced Damage in Kidney Epithelial LLC-PK1 Cells via Autophagy Regulation
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Aviculin Isolated from Lespedeza cuneata Induce Apoptosis in Breast Cancer Cells through Mitochondria-Mediated Caspase Activation Pathway
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