Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea
Daniel Torres-Mendoza Yisett González José Gómez-Reyes Héctor Guzmán José López-Perez William Gerwick Patricia Fernandez Marcelino Gutiérrez
Molecules, 2016-6
Daniel Torres-Mendoza
Torres-Mendoza Daniel
ORCID: 0000-0002-3540-4238
Hydroxyalkenylresorcinols from Stylogyne turbacensis 10.1021/np070081d
Five new cassane diterpenes from Myrospermum frutescens with activity against Trypanosoma cruzi 10.1021/np030010o
Novel cassane and cleistanthane diterpenes from Myrospermum frutescens: Absolute stereochemistry of the cassane diterpene series 10.1021/np049890c
Weakly antimalarial flavonol arabinofuranosides from Calycolpus warszewiczianus 10.1021/np050484i
Novel Cassane and Cleistanthane Diterpenes from Myrospermum frutescens :  Absolute Stereochemistry of the Cassane Diterpene Series. 10.1021/np068028x
Microbiota of Healthy Corals Are Active against Fungi in a Light-Dependent Manner 10.1021/cb500432j
Marine Diterpenoids as Potential Anti-Inflammatory Agents 10.1155/2015/263543
Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea 10.3390/molecules21060819
Pumilacidins from the Octocoral-Associated Bacillus sp. DT001 Display Anti-Proliferative Effects in Plasmodium falciparum 10.3390/molecules23092179
Patents on Endophytic Fungi Related to Secondary Metabolites and Biotransformation Applications 10.3390/jof6020058
Patents on Endophytic Fungi for Agriculture and Bio- and Phytoremediation Applications 10.3390/microorganisms8081237
Exploring the Antibacterial Activity of Pestalotiopsis spp. under Different Culture Conditions and Their Chemical Diversity Using LC–ESI–Q–TOF–MS 10.3390/jof6030140
Structurally Uncommon Secondary Metabolites Derived from Endophytic Fungi 10.3390/jof7070570
Yisett González
González Yisett
ORCID: 0000-0002-1623-9484
A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS 10.3390/biom8040109
A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages 10.1371/journal.pone.0084107
Marine Diterpenoids as Potential Anti-Inflammatory Agents 10.1155/2015/263543
Uprolides N, O and P from the Panamanian octocoral Eunicea succinea 10.3390/molecules21060819
Flavonoids from Boldoa purpurascens inhibit proinflammatory cytokines (TNF-α and IL-6) and the expression of COX-2 10.1002/ptr.6104
seco-briarellinone and briarellin S, two new eunicellin-based diterpenoids from the panamanian octocoral Briareum asbestinum 10.3390/md10112608
Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer's Disease 10.3233/JAD-170071
Hector M. Guzman
Guzman Hector M.
ORCID: 0000-0001-9928-8523
Bioacoustic Classification of Antillean Manatee Vocalization Spectrograms Using Deep Convolutional Neural Networks 10.3390/app10093286
Fisheries and conservation assessment of sharks in Pacific Panama 10.1002/aqc.3245
Caribbean coral reefs of Panama: Present status and future perspectives 10.1016/B978-044451388-5/50012-6
Decadal increase in seagrass biomass and temperature at the caricomp site in bocas del toro, panama 10.15517/rbt.v61i4.12854
A revision of the genus Muricea Lamouroux, 1821 (Anthozoa, Octocorallia) in the eastern Pacific. Part II 10.3897/zookeys.58114.7910
Leptogorgia christiae (Octocorallia: Gorgoniidae) a new shallow water gorgonian from Pacific Panama 10.1017/S0025315408001240
Meiofauna associated with a Pacific coral reef in Costa Rica 10.1007/BF00301379
Spatial patterns in reef-generated noise relate to habitats and communities: Evidence from a Panamanian case study 10.1016/j.jembe.2010.08.017
Failed recovery of a collapsed scallop (Argopecten ventricosus) fishery in Las Perlas Archipelago, Panama 10.2983/0730-8000(2007)26[9:FROACS]2.0.CO;2
Natural Disturbances and Mining of Panamanian Coral Reefs by Indigenous People 10.1046/j.1523-1739.2003.02308.x
Multiscale change in reef coral species diversity and composition in the Tropical Eastern Pacific 10.1007/s00338-017-1637-y
Revision of the genus adelogorgia bayer, 1958 (Cnidaria: Anthozoa: Octocorallia) with the description of three new species 10.11646/zootaxa.4369.3.2
Contamination of coral reefs by heavy metals along the Caribbean coast of Central America (Costa Rica and Panama) 10.1016/0025-326X(92)90708-E
Reproductive cycle of two commercial species of sea cucumber (Echinodermata: Holothuroidea) from Caribbean Panama 10.1007/s00227-002-0939-x
A new Muricea species (Cnidaria, Anthozoa, Octocorallia) from the eastern tropical Pacific 10.3897/zookeys.629.10828
Global human footprint on the linkage between biodiversity and ecosystem functioning in reef fishes 10.1371/journal.pbio.1000606
An assessment of metal contamination in mangrove sediments and leaves from Punta Mala Bay, Pacific Panama 10.1016/j.marpolbul.2004.11.047
Distribution, diversity, and conservation of coral reefs and coral communities in the largest marine protected area of Pacific Panama (Coiba Island) 10.1017/S0376892904001250
Reef recovery 20 years after the 1982-1983 El Niño massive mortality 10.1007/s00227-006-0495-x
Detection and identification of manatee individual vocalizations in Panamanian wetlands using spectrogram clustering 10.1121/1.5126504
Pumilacidins from the octocoral-associated bacillus sp. Dt001 display anti-proliferative effects in plasmodium falciparum 10.3390/molecules23092179
Reproductive traits and their relationship with water temperature in three common octocoral (Anthozoa: Octocoralia) species from the tropical eastern Pacific 10.5343/bms.2017.1051
Harvest history and current densities of the pearl oyster Pinctada mazatlanica (Bivalvia: Pteriidae) in Las Perlas and Coiba Archipelagos, Panama 10.2983/0730-8000(2008)27[691:HHACDO]2.0.CO;2
Macroalgal community response to herbivores and sediment deposition: an indicator of coral reef degradation 10.1007/s10811-019-01991-7
A revision of the genus Muricea Lamouroux, 1821 (Anthozoa, Octocorallia) in the eastern Pacific. Part I: Eumuricea Verrill, 1869 revisited 10.3897/zookeys.537.6025
Caribbean-wide, long-term study of seagrass beds reveals local variations, shifts in community structure and occasional collapse 10.1371/journal.pone.0090600
Reef coral reproduction in the eastern Pacific: Costa Rica, Panama and Galapagos Islands (Ecuador). IV. Agariciidae, recruitment and recovery of Pavona varians and Pavona sp.a 10.1007/s002270000286
Reproductive ecology of the azooxanthellate coral Tubastraea coccinea in the Equatorial Eastern Pacific: Part V. Dendrophylliidae (Marine Biology (2008) 153, (529-544) DOI: 10.1007/s00227-007-0827-5) 10.1007/s00227-008-0926-y
A crab swarm at an ecological hotspot: Patchiness and population density from AUV observations at a coastal, tropical seamount 10.7717/peerj.1770
Interspecific hybridization and restricted trans-Pacific gene flow in the Tropical Eastern Pacific Pocillopora 10.1111/j.1365-294X.2007.03672.x
Antitrypanosomal alkaloids from the marine bacterium Bacillus pumilus 10.3390/molecules170911146
Distribution patterns of the genus Pacifigorgia (Octocorallia: Gorgoniidae): Track compatibility analysis and parsimony analysis of endemicity 10.1111/j.1365-2699.2007.01810.x
Species richness change across spatial scales 10.1111/oik.05968
Reproductive ecology of the azooxanthellate coral Tubastraea coccinea in the Equatorial Eastern Pacific: Part V. Dendrophylliidae 10.1007/s00227-007-0827-5
Reef coral reproduction in the eastern Pacific: Costa Rica, Panama, and Galapagos Islands (Ecuador) - I. Pocilloporidae 10.1007/BF01313501
Antiplasmodial metabolites isolated from the marine octocoral Muricea austera 10.1021/np060007f
Abundance of manatees in Panama estimated from side-scan sonar 10.1002/wsb.793
Caribbean corals in crisis: Record thermal stress, bleaching, and mortality in 2005 10.1371/journal.pone.0013969
Restoration of Coral Reefs in Pacific Costa Rica 10.1111/j.1523-1739.1991.tb00123.x
Homoplasious colony morphology and mito-nuclear phylogenetic discordance among Eastern Pacific octocorals 10.1016/j.ympev.2016.02.023
Longest recorded trans-Pacific migration of a whale shark (Rhincodon typus) 10.1186/s41200-018-0143-4
Assessing the long-term effects of a catastrophic oil spill on subtidal coral reef communities off the Caribbean coast of Panama (1985–2017) 10.1007/s12526-020-01057-9
Reconstructing panama's total fisheries catches from 1950 to 2010: Highlighting data defi ciencies and management needs 10.7755/MFR.76.1_2.3
A new species of alcyonacean octocoral from the Peruvian zoogeographic region 10.1017/S0025315413001835
Pacifigorgia marviva (Anthozoa: Octocorallia) a new species from Coiba National Park, Pacific Panama 10.1017/S0025315411000373
Distribution and diversity of echinoderms (Asteroidea, Echinoidea, Holothuroidea) in the islands of the gulf of chiriqui, panama,Distribución y diversidad de equinodermos (Asteroidea, Echinoidea, Holothuroidea) en las islas del golfo de chiriquí, panamá 10.4067/S0718-19572012000100002
A revision of the genus Leptogorgia Milne Edwards & Haime, 1857 (Coelenterata: Octocorallia: Gorgoniidae) in the eastern Pacific 10.11646/zootaxa.1419.1.1
Bioindication potential of carbonic anhydrase activity in anemones and corals 10.1016/S0025-326X(00)00210-1
Leptolide, a new furanocembranolide diterpene from Leptogorgia alba 10.1021/np049745z
L-Galactose as a natural product: Isolation from a marine octocoral of the first α-L-galactosyl saponin 10.1016/j.tetlet.2004.08.170
Reef coral reproduction in the eastern Pacific: Costa Rica, Panamá, and Galápagos Islands (Ecuador). II. Poritidae 10.1007/BF00349785
Skeletal growth controls on Mg/Ca and P/Ca ratios in tropical Eastern Pacific rhodoliths (coralline red algae) 10.1016/j.chemgeo.2017.05.010
Sibling species in Montastraea annularis, coral bleaching, and the coral climate record 10.1126/science.255.5042.330
How many kinds of sclerite? Towards a morphometric classification of gorgoniid microskeletal components 10.1016/j.micron.2009.08.009
Widespread local chronic stressors in Caribbean coastal habitats 10.1371/journal.pone.0188564
Reef coral reproduction in the eastern Pacific: Costa Rica, Panamá, and the Galápagos Islands (Ecuador). VI. Agariciidae, Pavona clavus 10.1007/s00227-011-1673-z
Antimicrobial-producing Pseudoalteromonas from the marine environment of Panama shows a high phylogenetic diversity and clonal structure 10.1002/jobm.201800087
A new species of the genus Eugorgia (Cnidaria: Octocorallia: Gorgoniidae) from mesophotic reefs in the eastern Pacific 10.5343/bms.2013.1014
The song of the Southeast Pacific Humpback Whale (Megaptera novaeangliae) off Las Perlas Archipelago, Panama: Preliminary characterization 10.1578/AM.34.4.2008.458
Effects of titanium dioxide (TiO2) nanoparticles on caribbean reef-building coral (Montastraea faveolata) 10.1002/etc.2560
Sea Anemones (Cnidaria: Actiniaria and Corallimorpharia) from Panama,Anémonas de mar (Cnidaria: Actiniaria y Corallimorpharia) de Panamá 10.4067/S0718-19572009000300025
Stability and dynamic properties of octocoral communities in the Tropical Eastern Pacific 10.3354/meps12416
Geographic and temporal patterns of non-lethal attacks on humpback whales by killer whales in the eastern South Pacific and the Antarctic Peninsula 10.3354/esr00924
Mercury levels in coral reefs along the Caribbean coast of Central America 10.1016/S0025-326X(02)00318-1
A new species of Leptogorgia (Cnidaria: Anthozoa: Octocorallia) from the Mexican Pacific coast 10.5343/bms.2011.1103
Molecular phylogeny and DNA barcoding of tropical eastern Pacific shallow-water gorgonian octocorals 10.1007/s00227-014-2396-8
The abundance of false killer whale, pseudorca crassidens (Cetartiodactyla: Delphinidae) in coastal waters of golfo dulce and osa peninsula, Costa Rica,Abundancia de la falsa orca, pseudorca crassidens (Cetartiodactyla: delphinidae) en las aguas costeras del golfo dulce y la península de osa, Costa Rica 10.15517/RBT.V68I2.37196
Fishery of the green jack Caranx caballus (Osteichytes: Carangidae) in Las Perlas Archipelago, Pacific Panama 10.15517/rbt.v60i3.1806
Temporal mangrove dynamics in relation to coastal development in Pacific Panama 10.1016/j.jenvman.2005.02.004
Humpback whale movements in a narrow and heavily-used shipping passage, Chile 10.1016/j.marpol.2020.103990
Assessing the herbivore role of the sea-urchin Echinometra viridis: Keys to determine the structure of communities in disturbed coral reefs 10.1016/j.marenvres.2016.08.008
Population size and migratory connectivity of humpback whales wintering in Las Perlas Archipelago, Panama 10.1111/mms.12136
The phylogeny of Pacifigorgia (Coelenterata, Octocorallia, Gorgoniidae): A case study of the use of continuous characters in the systematics of the Octocorallia,La phylogénie de Pacifi gorgia (Coelenterata, Octocorallia, Gorgoniidae) : un cas d'étude de l'utilisation de caractéres continus dans la systématique des Octocorallia 10.5252/z2010n1a1
A comparison of coral reef and coral community fish assemblages in Pacific Panama and environmental factors governing their structure 10.1017/S0025315408002002
Coral Reef Community Structure at Caño Island, Pacific Costa Rica 10.1111/j.1439-0485.1989.tb00064.x
Chronology of mercury enrichment factors in reef corals from western Venezuela 10.1016/j.marpolbul.2008.09.023
Are U.S. coral reefs on the slippery slope to slime? 10.1126/science.1104258
Satellite tracking and sighting data analyses of Southeast Pacific humpback whales (Megaptera novaeangliae): Is the migratory route coastal or oceanic? 10.1578/AM.40.4.2014.329
Direct evidence for reproductive isolation among the three species of the Montastraea annularis complex in Central America (Panama and Honduras) 10.1007/s002270050061
A new species of the genus Psammogorgia (Cnidaria: Anthozoa: Octocorallia) from the Hannibal Bank in Pacific Panama 10.5343/bms.2019.0072
Density, size, and biomass of Diadema mexicanum (Echinoidea) in Eastern Tropical Pacific coral reefs 10.3354/ab00645
seco-briarellinone and briarellin S, two new eunicellin-based diterpenoids from the panamanian octocoral Briareum asbestinum 10.3390/md10112608
A revision of the genus Heterogorgia Verrill, 1868 (Anthozoa: Octocorallia: Plexauridae) 10.11646/zootaxa.2995.1.2
Migratory preferences of humpback whales between feeding and breeding grounds in the eastern South Pacific 10.1111/mms.12423
Variation in reef fish and invertebrate communities with level of protection from fishing across the Eastern Tropical Pacific seascape 10.1111/j.1466-8238.2010.00642.x
A review of toxic metal contamination in marine turtle tissues and its implications for human health 10.1016/j.rsma.2017.06.003
One-third of reef-building corals face elevated extinction risk from climate change and local impacts 10.1126/science.1159196
Genetic composition and connectivity of the antillean manatee (Trichechus manatus manatus) in Panama 10.1578/AM.43.4.2017.378
Seasonal variation in skeletal extension rate and stable isotopic (13C/12C and 18O/16O) composition in response to several environmental variables in the Caribbean reef coral Siderastrea siderea 10.3354/meps166109
Re-evaluation of using rhodolith growth patterns for paleoenvironmental reconstruction: An example from the Gulf of Panama 10.1016/j.palaeo.2016.10.038
First report of folliculinid ciliates affecting Caribbean scleractinian corals 10.1007/s00338-005-0068-3
Mapping the distribution of coral reefs and associated sublittoral habitats in Pacific Panama: A comparison of optical satellite sensors and classification methodologies 10.1080/01431160701258062
Antiplasmodial activity of bacilosarcin A isolated from the octocoral-associated bacterium Bacillus sp. collected in Panama 10.4103/0975-7406.92739
Reef coral reproduction in the equatorial eastern Pacific: Costa Rica, Panamá, and the Galápagos Islands (Ecuador). VII. Siderastreidae, Psammocora stellata and Psammocora profundacella 10.1007/s00227-012-1979-5
Mapping benthic faunal communities in the shallow and deep sediments of Las Perlas Archipelago, Pacific Panama 10.1016/j.marpolbul.2008.10.015
Two new species of gorgonian octocorals from the Tropical Eastern Pacific Biogeographic Region (Cnidaria, Anthozoa, Gorgoniidae) 10.3897/zookeys.350.6117
Movements and habitat use by southeast pacific humpback whales (megaptera novaeangliae) satellite tracked at two breeding sites 10.1578/AM.43.2.2017.139
A mechanism of transmission and factors affecting coral susceptibility to Halofolliculina sp. infection 10.1007/s00338-008-0419-y
Survival, growth, and recruitment of Octocoral species (Coelenterata: Octocorallia) in Coiba National Park, Pacific Panama 10.5343/bms.2012.1092
New eunicellin-type diterpenes from the Panamanian octocoral Briareum asbestinum 10.3390/md18020084
Historical decline in coral reef growth after the Panama Canal 10.1579/07-A-372.1
Microbiota of healthy corals are active against fungi in a light-dependent manner 10.1021/cb500432j
Short-term ecological consequences of a major oil spill on Panamanian subtidal reef corals 10.1007/BF00301900
Macroalgal communities on multi-stressed coral reefs in the Caribbean: Long-term changes, spatial variations, and relationships with environmental variables 10.1016/j.seares.2016.09.001
An ITS region phylogeny of Siderastrea (Cnidaria: Anthozoa): Is S. glynni endangered or introduced? 10.1007/s00338-005-0497-z
A new alcyonacean species (Cnidaria: Anthozoa: Octocorallia) from a seamount in the tropical Pacific Ocean 10.5343/bms.2018.0027
Antiprotozoal activity against Plasmodium falciparum and Trypanosoma cruzi of aeroplysinin-1 isolated from the new sponge Aplysina chiriquensis 10.1080/13880200500406503
Accumulation of trace elements in leatherback turtle (Dermochelys coriacea) eggs from the south-western Caribbean indicates potential health risks to consumers 10.1016/j.chemosphere.2019.125424
Population assessment of the pacific green spiny lobster Panulirus gracilis in Pacific Panama 10.2983/0730-8000(2008)27[907:PAOTPG]2.0.CO;2
Behavioral States Related to Environmental Conditions and Fisheries During Olive Ridley Turtle Migration From Pacific Panama 10.3389/fmars.2019.00770
Metal contents of marine turtle eggs (Chelonia mydas; Lepidochelys olivacea) from the tropical eastern pacific and the implications for human health 10.1080/03601234.2016.1191888
Population decline and the effects of disturbances on the structure and recovery of octocoral communities (Coelenterata: Octocorallia) in Pacific Panama 10.1017/S0025315414000915
Benthic community recovery from smallscale damage on marginal caribbean reefs: An example from Panama 10.5343/bms.2012.1075
Bioerosion by the sea urchin Diadema mexicanum along Eastern Tropical Pacific coral reefs 10.1111/maec.12372
Acoustic mapping of fish aggregation areas to improve fisheries management in Las Perlas Archipelago, Pacific Panama 10.1016/j.ocecoaman.2010.07.001
Distichopora robusta sp. nov., the first shallow-water stylasterid (Cnidaria: Hydrozoa: Stylasteridae) from the tropical eastern Pacific 10.1017/S0025315404010239h
Short-term recovery of humpback whales after percutaneous satellite tagging 10.1002/jwmg.21235
Environmental interpretation using insoluble residues within reef coral skeletons: problems, pitfalls, and preliminary results 10.1007/BF00303782
Caribbean coral growth influenced by anthropogenic aerosol emissions 10.1038/ngeo1780
A new species of alcyonacean octocoral from the Galápagos Archipelago 10.1017/S0025315405011732
Ecological effects of a major oil spill on Panamanian coastal marine communities 10.1126/science.243.4887.37
Uprolides N, O and P from the Panamanian octocoral Eunicea succinea 10.3390/molecules21060819
Leptogorgia ignita, a new shallow-water coral species (Octocorallia: Gorgoniidae) from the tropical eastern Pacific 10.1017/S0025315408001902
Broadening reef protection across the Marine Conservation Corridor of the Eastern Tropical Pacific: Distribution and diversity of reefs in Las Perlas Archipelago, Panama 10.1017/S0376892908004542
Population assessment of the conch Strombus galeatus (Gastropoda, Strombidae) in Pacific Panama 10.2983/0730-8000(2008)27[889:PAOTCS]2.0.CO;2
Effects of chronic oil-sediment pollution on the reproduction of the Caribbean reef coral Siderastrea siderea 10.1016/0025-326X(93)90068-U
Annual reproductive cycle, spatial distribution, abundance, and size structure of Oreaster reticulatus (Echinodermata: Asteroidea) in Bocas del Toro, Panama 10.1007/s00227-002-0898-2
Coral reef distribution, status and geomorphology-biodiversity relationship in Kuna Yala (San Blas) archipelago, Caribbean Panama 10.1007/s00338-004-0444-4
Potential vessel collisions with Southern Hemisphere humpback whales wintering off Pacific Panama 10.1111/j.1748-7692.2012.00605.x
Patricia Llanes Fernandez
Llanes Fernandez Patricia
ORCID: 0000-0002-0762-0566
Hemolysis-induced lethality involves inflammasome activation by heme. 10.1073/pnas.1405023111
Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis. 10.1186/1742-2094-11-48
A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages. 10.1371/journal.pone.0084107
AFLP polymorphisms allow high resolution genetic analysis of American Tegumentary Leishmaniasis agents circulating in Panama and other members of the Leishmania genus. 10.1371/journal.pone.0073177
Potential immunotargets for Alzheimer's disease treatment strategies. 10.3233/JAD-2012-121222
seco-Briarellinone and briarellin S, two new eunicellin-based diterpenoids from the Panamanian octocoral Briareum asbestinum. 10.3390/md10112608
Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production. 10.1182/blood-2011-08-375303
TLR4 recognizes Pseudallescheria boydii conidia and purified rhamnomannans. 10.1074/jbc.M110.181255
Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation. 10.1074/jbc.M110.146076
Heme induces neutrophil migration and reactive oxygen species generation through signaling pathways characteristic of chemotactic receptors. 10.1074/jbc.M703570200
Characterization of heme as activator of Toll-like receptor 4. 10.1074/jbc.M610737200
An alpha-glucan of Pseudallescheria boydii is involved in fungal phagocytosis and Toll-like receptor activation. 10.1074/jbc.M511417200
Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea 10.3390/molecules21060819
Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles. 10.1039/c6ob01149g
Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer’s drug discovery 10.2147/CIA.S134605
Both B-1a and B-1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody-secreting cells. 10.1111/imm.12909
Total IgM and Anti-Phosphatidylcholine IgM Antibody Secretion Continue After Clearance of Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection. 10.1007/s00408-017-0019-0
Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer's Disease. 10.3233/jad-170071
Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease. 10.1021/acschemneuro.6b00386
Marine Diterpenoids as Potential Anti-Inflammatory Agents. 10.1155/2015/263543
A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS 10.3390/biom8040109
Hexahydropyrrolo[2,3-b]indole Compounds as Potential Therapeutics for Alzheimer’s Disease 10.1021/acschemneuro.9b00297
José Luis López-Pérez
López-Pérez José Luis / López-Pérez, JL
ORCID: 0000-0002-3728-7602
Analgesic and anti-inflammatory activity of podophyllotoxin derivatives 10.3109/13880209.2012.749921
Structural Diversity from the Transannular Cyclizations of Natural Germacrone and Epoxy Derivatives: A TheoreticalExperimental Study 10.1002/chem.201300662
Synthesis, Bioevaluation and Structural Study of Substituted Phthalazin-1(2H)-ones Acting as Antifungal Agents 10.3390/molecules18033479
3-Phenylcoumarins as Inhibitors of HIV-1 Replication 10.3390/molecules17089245
Synthesis and Antimitotic and Tubulin Interaction Profiles of Novel Pinacol Derivatives of Podophyllotoxins 10.1021/jm2017573
Total Synthesis of (+)-seco-C-Oleanane via Stepwise Controlled Radical Cascade Cyclization 10.1021/jo201968t
Antimalarial activity of imidazo[2,1-a]isoindol-5-ol derivatives and related compounds 10.1016/j.ejmech.2011.08.043
Antidepressant-like profile and MAO-A inhibitory activity of 4-propyl-2H-benzo[h]-chromen-2-one 10.1016/j.lfs.2010.04.001
Vasoactive effects of different fractions from two Panamanians plants used in Amerindian traditional medicine 10.1016/j.jep.2010.06.036
New Pathways in Transannular Cyclization of Germacrone [Germacra-1(10),4,7(11)-trien-8-one]: Evidence Regarding a Concerted Mechanism 10.1021/ol901066x
Pyrazolo[3,4,5-de]phthalazine. Syntheses of a practically unknown heterocyclic system 10.1016/j.tet.2008.12.072
Simple dihydrosphyngosine analogues with potent activity against MDR-Mycobacterium tuberculosis 10.1016/j.bmcl.2009.07.147
Vasorelaxant properties of acid and neutral fractions of Dimerocostus strobilaceus Kuntze used by Kuna Indians of Panama 10.1016/j.jep.2009.04.011
A new cytotoxic friedelane acid--pluricostatic acid--and other compounds from the leaves of Marila pluricostata. 10.3390/molecules13112915
Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization 10.1016/j.bmc.2008.04.054
Leishmanicidal and trypanocidal activities of 2-aminocyclohexanol and 1,2-cyclohexanediamine derivatives 10.1016/j.bmcl.2007.10.102
Preliminary study of the anti-inflammatory activity of hexane extract and fractions from Bursera simaruba (Linneo) Sarg. (Burseraceae) leaves 10.1016/j.jep.2007.10.034
A new coumarin from the fruits of Coutarea hexandra 10.1080/14786410701371116
NAPROC-13: a database for the dereplication of natural product mixtures in bioassay-guided protocols 10.1093/bioinformatics/btm516
Regioselective synthesis of 1-alkyl- or 1-aryl-1H-indazoles via copper-catalyzed cyclizations of 2-haloarylcarbonylic compounds 10.1021/ol062890e
Synthesis of a 10-membered ring with eleutheside functionality by Nozaki-Hiyama-Kishi coupling 10.1016/j.tet.2007.08.099
[1,3]diazaheterofused isoindolol derivatives displaying anxiolytic-like effects on mice 10.1016/j.bmcl.2007.04.080
Anti-HIV activity of stilbene-related heterocyclic compounds 10.1016/j.bmcl.2006.04.087
Constituents and biological activities of Schinus polygamus 10.1016/j.jep.2006.03.028
Correct structures of Diels-Alder adducts from the natural cyclolignan thuriferic acid and its 8-epimer 10.1016/j.tet.2005.11.068
Cytotoxic and antimicrobial benzophenones from the leaves of Tovomita longifolia 10.1021/np050338c
Synthesis and evaluation of some lipidic aminoalcohols and diamines as immunomodulators 10.1016/j.bmcl.2006.08.113
Vasorelaxant activity of phthalazinones and related compounds 10.1016/j.bmcl.2006.02.003
4-phenylcoumarins as HIV transcription inhibitors 10.1016/j.bmcl.2005.07.041
Analgesic-antiinflammatory properties of Proustia pyrifolia 10.1016/j.jep.2005.02.012
Anxiolytic effects of benzalphthalides 10.1016/j.bmcl.2005.06.031
Cytotoxic 4-phenylcoumarins from the leaves of Marila pluricostata 10.1021/np049642g
Homocoupling versus reduction of radicals: An experimental and theoretical study of Ti(iii)-mediated deoxygenation of activated alcohols 10.1039/c4ob02290d
NAPROC-13: A carbon NMR web database for the structural elucidation of natural products and food phytochemicals 10.1007/978-3-319-07581-5_2
Vasorelaxant effects in aortic rings of eight diterpenoids isolated from three Venezuelan plants 10.1590/S0102-695X2013000500008
The Importance of Structural Manipulation of Natural Compounds in Drug Discovery and Development 10.1002/9781118260005.ch4
Visual evaluation of clustered molecules in the process of new drugs design 10.1007/978-3-642-02115-2_1
NATPRO-C13 - An interactive tool for the structural elucidation of natural compounds 10.1007/978-3-540-74972-1_52
Two new dammarane triterpenoids from Kageneckia angustifolia D. Don 10.1002/mrc.1656
Mesuol, a natural occurring 4-phenylcoumarin, inhibits HIV-1 replication by targeting the NF-κB pathway 10.1016/j.antiviral.2005.02.006
Anti-inflammatory activity of leaf extract and fractions of Bursera simaruba (L.) Sarg (Burseraceae) 10.1016/j.jep.2004.02.009
Synthesis and cytotoxicity of hydrophobic esters of podophyllotoxins 10.1016/j.bmcl.2003.12.039
Bioactive phenolic derivatives from Acaena splendens methanol extract 10.1002/ptr.997
Methyl psilalate: A new antimicrobial metabolite from Psila boliviensis 10.1055/s-2002-19866
Anti-Trypanosoma activity of some natural stilbenoids and synthetic related heterocyclic compounds 10.1016/S0960-894X(01)00562-5
A (1→3)-β-D-linked heptasaccharide is the unit ligand for glucan pattern recognition receptors on human monocytes 10.1016/S1286-4579(01)01436-8
Leishmanicidal activity of some stilbenoids and related heterocyclic compounds 10.1016/S0960-894X(01)00387-0
A role for dipole moment in the activity of cyclolignans 10.1016/S0166-1280(00)00354-7
9-epi-labdane diterpenoids from Nolana rostrata var. rostrata 10.1016/S0031-9422(97)00047-2
The stereochemistry of thuriferic and epithuriferic acids 10.1016/0040-4020(96)00161-5
Neo-clerodane diterpenoids from Croton schiedeanus 10.1016/S0031-9422(02)00516-2
The imidazo[2,1-a]isoindole system. A new skeletal basis for antiplasmodial compounds 10.1016/S0960-894X(03)00509-2
Leishmanicidal activity of some aliphatic diamines and amino-alcohols 10.1016/S0960-894X(01)00837-X
Long-chain aminoalcohol and diamine derivatives induce apoptosis through a caspase-3 dependent pathway 10.1016/S0960-894X(02)00476-6
Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A(2) 10.1016/S0960-894X(99)00680-0
Synthesis and inotropic activity of hydroindene derivatives 10.1016/S0968-0896(99)00251-5
Synthesis and pharmacological activity of diarylindole derivatives. Cytotoxic agents based on combretastatins 10.1016/S0960-894X(99)00370-4
Heterolignanolides. Synthesis of a new family of thienolignanolides 10.1016/S0040-4039(98)00116-6
Synthesis and antineoplastic activity of combretastatin analogues: Heterocombretastatins 10.1016/S0223-5234(99)80078-6
Synthesis of thiazolo[3,2-a]pyridines from enaminoesters by tandem conjugate addition-cyclization 10.1016/S0040-4039(97)10574-3
Antifungal activity of scopoletin and its differential accumulation in Ulmus pumila and Ulmus campestris cell suspension cultures infected with Ophiostoma ulmi spores 10.1016/S0168-9452(97)00057-5
A new approach to the synthesis of podophyllotoxin based on epimerization reactions 10.1016/0040-4039(96)00355-3
Synthesis and Diels-Alder reactivity of simple 1-phenoxy-1,3-dienes 10.1016/0040-4039(96)01525-0
HETEROLIGNANOLIDES - ANTITUMOR-ACTIVITY OF FURYL-ANALOG, THIENYL-ANALOG, AND PYRIDYL-ANALOG OF LIGNANOLIDES 10.1002/ardp.19953280503
METHYL ETHERS OF PODOPHYLLOTOXIN-RELATED CYCLOLIGNANS 10.1021/np50120a008
NOVEL AND UNEXPECTED ONE-POT SYNTHESIS OF 7,7-DIOXO-14-OXA-7-LAMBDA(6)-THIADIBENZO[A,J]ANTHRACENE-2,12-DISULFONIC ACID FROM ALPHA-TETRALONE 10.1039/p19950002455
REACTION OF SELENIUM DIOXIDE WITH 3-HYDROXY-1,6-DIOLEFINS - FORMATION OF 8-OXA-3-SELENABICYCLO[3,2,1(1,5)]OCTANES AND OTHER SELENOORGANO COMPOUNDS 10.1016/0040-4039(95)01684-A
REACTIONS OF DIENES WITH SELENIUM DIOXIDE .3. SELENOLABDANES FROM METHYL 15-O-ACETYLISOCUPRESSATE 10.1016/0040-4020(95)00656-S
SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF COMBRETASTATIN ANALOGS - NAPHTHYLCOMBRETASTATINS AND RELATED-COMPOUNDS 10.1016/0960-894X(95)00008-H
Synthesis, antitumoral and antiviral evaluation of halo- and demethyl-yatein derivatives 10.1002/ardp.19953280903
A VERSATILE APPROACH TO THE SYNTHESIS OF COMBRETASTATINS 10.1021/np50110a002
CHIRAL RECEPTOR FOR N-BENZYLOXYCARBONYL AMINO-ACID DERIVATIVES 10.1016/S0040-4039(00)76239-3
N-SUBSTITUTED PYRROLINONES FROM ENAMINES AND ALPHA-DICARBONYLS 10.1016/S0040-4020(01)85268-6
STEREOCHEMICAL CONTROL OF PERHYDROINDANES FOR THE SYNTHESIS OF CARDENOLIDE ANALOGS 10.1016/S0040-4039(00)78471-1
SYNTHESIS OF HETEROCYCLIC-ANALOGS OF LIGNANS (HETEROLIGNANS) 10.1002/ardp.19943270206
8-HYDROXY-LABDANES FROM JUNIPERUS-THURIFERA 10.1016/0031-9422(92)83133-J
PLANTS OF NEW-CALEDONIA .132. ISOLATION AND 2D NMR-STUDIES OF ALKALOIDS FROM COMPTONELLA SESSILIFOLIOLA 10.1055/s-2006-960053
LIGNANS FROM JUNIPERUS-THURIFERA 10.1016/S0031-9422(00)98111-1
PLANTS OF NEW-CALEDONIA .115. MONOTERPENE ALKALOIDS FROM COELOSPERMUM-BILLARDIERI 10.1021/np50059a002
REVISED ASSIGNMENTS OF THE C-13 NMR-SPECTRUM OF HIBALACTONE USING 2D HETERONUCLEAR H-1/C-13 CORRELATIONS 10.1002/mrc.1260250114
2 NEW CINNAMYL ISOVALERATE DERIVATIVES FROM JUNIPERUS-THURIFERA LEAVES 10.1021/np50046a021
Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea 10.3390/molecules21060819
Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways 10.3390/molecules22020321
Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum 10.1016/j.ijpddr.2017.06.003
Cytotoxic phloroglucinol meroterpenoid from Eugenia umbelliflora fruits 10.1016/j.phytol.2018.07.004
An Efficient Microkinetic Modeling Protocol: Start with Only the Dominant Mechanisms, Adjust All Parameters, and Build the Complete Model Incrementally 10.1021/acscatal.9b00522
Germacrone Derivatives as new Insecticidal and Acaricidal Compounds: A Structure-Activity Relationship 10.3390/molecules24162898
Mimicking Halimane Synthases: Monitoring a Cascade of Cyclizations and Rearrangements from Epoxypolyprenes 10.1021/acs.joc.9b01996
Synthesis of Cannabinoids: “In Water” and “On Water” Approaches: Influence of SDS Micelles 10.1021/acs.joc.0c02698
Anthelmintic activity of aminoalcohol and diamine derivatives against the gastrointestinal nematode Teladorsagia circumcincta 10.1016/j.vetpar.2021.109496
Marcelino Gutierrez
Gutierrez Marcelino
ORCID: 0000-0003-1423-3772
Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea 10.3390/molecules21060819
Imaging mass spectrometry and MS/MS molecular networking reveals chemical interactions among cuticular bacteria and pathogenic fungi associated with fungus-growing ants 10.1038/s41598-017-05515-6
Antimicrobial‐producing Pseudoalteromonas from the marine environment of Panama shows a high phylogenetic diversity and clonal structure 10.1002/jobm.201800087
Imaging Mass Spectrometry of a Coral Microbe Interaction with Fungi 10.1007/s10886-013-0320-1
Leptolide, a new furanocembranolide diterpene from Leptogorgia alba 10.1021/np049745z
Cannabinomimetic lipid from a marine cyanobacterium 10.1021/np200610t
Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula 10.1021/jo900578j
Antiprotozoal activity against Plasmodium falciparum and Trypanosoma cruzi of aeroplysinin-1 isolated from the new sponge Aplysina chiriquensis 10.1080/13880200500406503
Antiplasmodial activity of bacilosarcin A isolated from the octocoral-associated bacterium Bacillus sp. collected in Panama 10.4103/0975-7406.92739
Antitrypanosomal alkaloids from the marine bacterium Bacillus pumilus 10.3390/molecules170911146
L-Galactose as a natural product: Isolation from a marine octocoral of the first α-L-galactosyl saponin 10.1016/j.tetlet.2004.08.170
MS/MS networking guided analysis of molecule and gene cluster families 10.1073/pnas.1303471110
Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new Guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida 10.1021/np800121a
seco-briarellinone and briarellin S, two new eunicellin-based diterpenoids from the panamanian octocoral Briareum asbestinum 10.3390/md10112608
Dudawalamides A-D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens 10.1021/acs.jnatprod.7b00034
Antiplasmodial metabolites isolated from the marine octocoral Muricea austera 10.1021/np060007f
A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages 10.1371/journal.pone.0084107
Microbiota of healthy corals are active against fungi in a light-dependent manner 10.1021/cb500432j
Toxins and pharmacologically active compounds from species of the family Bufonidae (Amphibia, Anura) 10.1016/j.jep.2016.12.021
Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides 10.1021/ac900114t
Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium lyngbya majuscula 10.1021/np9005184
Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer's Disease 10.3233/JAD-170071
Pumilacidins from the Octocoral-Associated Bacillus sp. DT001 Display Anti-Proliferative Effects in Plasmodium falciparum 10.3390/molecules23092179
A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS 10.3390/biom8040109
Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and molecular networking 10.1038/s41598-019-39583-7
Antiparasitic Compounds from the Panamanian Marine Bacterium Pseudomonas aeruginosa https://doi.org/10.1177/1934578X1901400109
Fungus-Growing Ant’s Microbial Interaction of Streptomyces sp. and Escovopsis sp. through Molecular Networking and MALDI Imaging https://doi.org/10.1177/1934578X1901400117
New Eunicellin-Type Diterpenes from the Panamanian Octocoral Briareum asbestinum 10.3390/md18020084
Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién 10.1371/journal.pone.0214193
19-Hydroxy-bufalin, a major bufadienolide isolated from the parotoid gland secretions of the Panamanian endemic toad Rhinella centralis (Bufonidae), inhibits the growth of Trypanosoma cruzi 10.1016/j.toxicon.2020.02.009
Reproducible molecular networking of untargeted mass spectrometry data using GNPS 10.1038/s41596-020-0317-5
Genome Mining, Microbial Interactions, and Molecular Networking Reveals New Dibromoalterochromides from Strains of Pseudoalteromonas of Coiba National Park-Panama 10.3390/md18090456
Metabolites from Microbes Isolated from the Skin of the Panamanian Rocket Frog Colostethus panamansis (Anura: Dendrobatidae) 10.3390/metabo10100406
Antimicrobial Secretions of Toads (Anura, Bufonidae): Bioactive Extracts and Isolated Compounds against Human Pathogens 10.3390/antibiotics9120843
Antibacterial Activity of Volatile Organic Compounds Produced by the Octocoral-Associated Bacteria Bacillus sp. BO53 and Pseudoalteromonas sp. GA327 10.3390/antibiotics9120923
Bufadienolides from the Skin Secretions of the Neotropical Toad Rhinella alata (Anura: Bufonidae): Antiprotozoal Activity against Trypanosoma cruzi 10.3390/molecules26144217