The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria
Yueying Li
C. Benjamin Naman
Kelsey L. Alexander
Huashi Guan
William H. Gerwick
Marine Drugs, 2020-10-6
C. Benjamin Naman
Naman C. Benjamin
ORCID: 0000-0002-4361-506X
Computer-Assisted Structure Elucidation of Black Chokeberry (Aronia melanocarpa) Fruit Juice Isolates with a New Fused Pentacyclic Flavonoid Skeleton.
10.1021/acs.orglett.5b01284
Northalrugosidine is a bisbenzyltetrahydroisoquinoline alkaloid from Thalictrum alpinum with in vivo antileishmanial activity.
10.1021/np501028u
Pyrrole alkaloids with potential cancer chemopreventive activity isolated from a goji berry-contaminated commercial sample of African mango.
10.1021/jf500802x
Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum.
10.1021/acs.jnatprod.5b01131
A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani.
10.1021/acsinfecdis.5b00081
Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium.
10.1021/acs.jnatprod.6b00907
Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata.
10.3390/md15040121
Streptomyces artemisiae MCCB 248 isolated from Arctic fjord sediments has unique PKS and NRPS biosynthetic genes and produces potential new anticancer natural products.
10.1007/s13205-017-0610-3
Preparative Separation and Purification of Trichothecene Mycotoxins from the Marine Fungus Fusarium sp. LS68 by High-Speed Countercurrent Chromatography in Stepwise Elution Mode
10.3390/md16020073
5-Hydroxycyclopenicillone Inhibits β-Amyloid Oligomerization and Produces Anti-β-Amyloid Neuroprotective Effects In Vitro.
10.3390/molecules22101651
Bioassay-Guided Isolation of Antioxidant and Cytoprotective Constituents from a Maqui Berry (Aristotelia chilensis) Dietary Supplement Ingredient As Markers for Qualitative and Quantitative Analysis.
10.1021/acs.jafc.7b03261
5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34.
10.3390/md15080260
Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species.
10.1021/acs.jnatprod.7b00367
MetaRiPPquest: A Peptidogenomics Approach for the Discovery of Ribosomally Synthesized and Post-translationally Modified Peptides
10.1101/227504
Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β.
10.1021/acschemneuro.7b00527
Usage, biological activity, and safety of selected botanical dietary supplements consumed in the United States.
10.1016/j.jtcme.2018.01.006
Phytodrugs and Immunomodulators for the Therapy of Leishmaniasis
10.1016/b978-0-08-102081-4.00009-5
Modern Natural Products Drug Discovery and Its Relevance to Biodiversity Conservation
10.1016/b978-0-12-804765-1.00005-9
Pharmaceuticals, Plant Drugs
10.1016/b978-0-12-394807-6.00163-5
DNA Binding and Molecular Dynamic Studies of Polycyclic Tetramate Macrolactams (PTM) with Potential Anticancer Activity Isolated from a Sponge-Associated Streptomyces zhaozhouensis subsp. mycale subsp. nov.
10.1007/s10126-018-9866-9
Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice.
10.3389/fncel.2018.00396
Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.
10.1016/j.ejmech.2018.10.024
A new lateral root growth inhibitor from the sponge-derived fungus Aspergillus sp. LS45
10.1016/j.bmcl.2019.04.051
9-Methylfascaplysin Is a More Potent Aβ Aggregation Inhibitor than the Marine-Derived Alkaloid, Fascaplysin, and Produces Nanomolar Neuroprotective Effects in SH-SY5Y Cells.
10.3390/md17020121
25C-NBOMe, a Novel Designer Psychedelic, Induces Neurotoxicity 50 Times More Potent Than Methamphetamine In Vitro.
10.1007/s12640-019-0012-x
Schekwanglupaside C, a new lupane saponin from Schefflera kwangsiensis, is a potent activator of sarcoplasmic reticulum Ca2+-ATPase.
10.1016/j.fitote.2019.04.005
A Systematic Review of Recently Reported Marine Derived Natural Product Kinase Inhibitors.
10.3390/md17090493
Isolation and Analysis of Antioxidant Phytochemicals from Black Chokeberry, Maqui, and Goji Berry Dietary Supplements
10.1021/bk-2018-1286.ch001
Investigation of Vietnamese plants for potential anticancer agents
10.1007/s11101-014-9335-7
Phthalideisoquinoline Hemiacetal Alkaloids from Corydalis decumbens That Inhibit Spontaneous Calcium Oscillations, including Alkyl Derivatives of (+)-Egenine That Are Strikingly Levorotatory
10.1021/acs.jnatprod.9b00247
Prospects of multitarget drug designing strategies by linking molecular docking and molecular dynamics to explore the protein–ligand recognition process
10.1002/ddr.21673
Three New Diketopiperazines from the Previously Uncultivable Marine Bacterium Gallaecimonas mangrovi HK-28 Cultivated by iChip.
10.1002/cbdv.202000221
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities.
10.1016/j.cels.2019.09.004
New Dihydroisocoumarin Root Growth Inhibitors From the Sponge-Derived Fungus Aspergillus sp. NBUF87.
10.3389/fmicb.2019.02846
Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties.
10.1021/acschembio.9b00992
The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria
10.3390/md18100508
Applying a Chemogeographic Strategy for Natural Product Discovery from the Marine Cyanobacterium Moorena bouillonii
10.3390/md18100515
Progress in the Development of Eukaryotic Elongation Factor 2 Kinase (eEF2K) Natural Product and Synthetic Small Molecule Inhibitors for Cancer Chemotherapy
10.3390/ijms22052408
Metabolomic Characterization of a cf. Neolyngbya Cyanobacterium from the South China Sea Reveals Wenchangamide A, a Lipopeptide with In Vitro Apoptotic Potential in Colon Cancer Cells
10.3390/md19070397
Kelsey Alexander
Alexander Kelsey
/ Kelsey L. Alexander
ORCID: 0000-0002-4727-5349
Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A
10.1039/D0CC03055D
The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria
10.3390/md18100508
A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria
10.3390/md19010020
Cyclic (Alkyl)(Amino)Carbene (CAAC) Gold(I) Complexes as Chemotherapeutic Agents
10.1002/chem.202004317
William Gerwick
Gerwick William
ORCID: 0000-0003-1403-4458
Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata
10.3390/md15040121
Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group
10.3390/md16050163
Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease
10.3390/molecules23061472
MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria
10.3390/md16120505
Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore
10.3390/md17010072
Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke
10.3390/md18070374
A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria
10.3390/md19010020
Kalkitoxin Reduces Osteoclast Formation and Resorption and Protects against Inflammatory Bone Loss
10.3390/ijms22052303
Dudawalamides A–D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens
10.1021/acs.jnatprod.7b00034
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity
10.1021/acs.jmedchem.7b00671
5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34
10.3390/md15080260
The Face of a Molecule
10.1021/acs.jnatprod.7b00624
Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research
10.1038/s41598-017-13923-x
A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit
10.1021/acschembio.7b00746
Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group
10.1021/acs.jnatprod.7b00917
Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp.
10.1021/acs.joc.8b00028
Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β
10.1021/acschemneuro.7b00527
Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module
10.1021/acschembio.8b00252
Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta
10.1021/acschembio.8b00910
Structural Basis of Polyketide Synthase O-Methylation
10.1021/acschembio.8b00687
Dragocins A−D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium
10.1021/acs.orglett.8b03712
Marine natural products as potential anti-tubercular agents
10.1016/j.ejmech.2019.01.026
Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp.
10.1021/acs.orglett.8b04050
Nature's Combinatorial Biosynthesis Produces Vatiamides A–F
10.1002/anie.201902571
Nature's Combinatorial Biosynthesis Produces Vatiamides A–F
10.1002/ange.201902571
Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens
10.1021/acs.jnatprod.9b00549
Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain
10.1021/acs.jmedchem.9b00294
Commensal oralRothia mucilaginosaproduces enterobactin – a metal chelating siderophore
10.1101/2020.02.20.956391
Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity
10.3390/molecules25071604
Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore
10.1128/mSystems.00161-20
Correction to “Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp.”
10.1021/acs.orglett.0c02252
The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria
10.3390/md18100508
Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2
10.1021/acs.jnatprod.0c00968
Total Synthesis of Laucysteinamide A, a Monomeric Congener of Somocystinamide A
10.1021/acs.jnatprod.0c01317
Cyanobacteria-shrimp colonies in the Mariana Islands
10.1007/s10452-021-09837-6
Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium
10.1021/acs.jnatprod.0c01383
SIRT1 Activation Enhancing 8,3′-Neolignans from the Twigs of Corylopsis coreana Uyeki
10.3390/plants10081684
First Total Synthesis and Structure–Activity Relationship of Iheyamide A, an Antitrypanosomal Linear Peptide Isolated from a Dapis sp. Marine Cyanobacterium
10.1021/acs.jnatprod.1c00792
