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Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis

Serena Camassa Ivana Palucci Raffaella Iantomasi Tiziana Cubeddu Mariachiara Minerva Flavio De Maio Samuel Jouny Elisa Petruccioli Delia Goletti Francesco Ria Michela Sali Maurizio Sanguinetti Riccardo Manganelli Stefano Rocca Priscille Brodin Giovanni Delogu

Frontiers in cellular and infection microbiology, 2017

https://doi.org/10.3389/fcimb.2017.00137

Mariachiara Minerva

Minerva Mariachiara

ORCID: 0000-0003-1518-7050

Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection 10.1111/joim.12714

Impact of Protein Domains on PE_PGRS30 Polar Localization in Mycobacteria 10.1371/journal.pone.0112482

PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2 10.1371/journal.pone.0150800

Evaluation of PE_PGRS33 as a potential surface target for humoral responses against Mycobacterium tuberculosis 10.1093/femspd/ftx100

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis 10.3389/fcimb.2017.00137

Maurizio Sanguinetti

Sanguinetti Maurizio

ORCID: 0000-0002-9780-7059

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Mannose-binding lectin codon 54 gene polymorphism and vulvovaginal candidiasis: A systematic review and meta-analysis 10.1155/2014/738298

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The future of fungal susceptibility testing 10.2217/fmb.14.55

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Involvement of Enterococcus faecalis small RNAs in stress response and virulence 10.1128/IAI.01900-14

Faecal transplantation for Clostridium difficile infection. Three cases treated in Italy 10.1016/j.dld.2013.12.011

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Development and validation of an in-house database for matrix-assisted laser desorption ionization-time of flight mass spectrometry-based yeast identification using a fast protein extraction procedure 10.1128/JCM.03355-13

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GIV Noroviruses in Wastewaters and in Stool Specimens from Hospitalized Patients 10.1007/s12560-013-9121-5

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Effects of amphotericin B on Aspergillus flavus clinical isolates with variable susceptibilities to the polyene in an experimental model of systemic aspergillosis 10.1093/jac/dkt232

Risks of "Blind" Automated identification systems in medical microbiology 10.1128/JCM.02238-13

The equine antimicrobial peptide eCATH1 is effective against the facultative intracellular pathogen rhodococcus equi in mice 10.1128/AAC.02044-12

Novel macrocyclic amidinoureas: Potent non-azole antifungals active against wild-type and resistant Candida species 10.1021/ml400187w

Update on antifungal resistance and its clinical impact 10.1007/s12281-013-0143-0

Antifungal activity of the noncytotoxic human peptide hepcidin 20 against fluconazole-resistant Candida glabrata in human vaginal fluid 10.1128/AAC.00904-13

Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization-time of flight mass spectrometry analysis 10.1128/JCM.00903-13

A fast and quantitative evaluation of the Aspergillus fumigatus biofilm adhesion properties by means of digital pulsed force mode 10.1016/j.apsusc.2013.04.128

Redox balance via lactate dehydrogenase is important for multiple stress resistance and virulence in enterococcus faecalis 10.1128/IAI.01299-12

Human monoclonal antibody-based therapy in the treatment of invasive candidiasis 10.1155/2013/403121

Enterococcal Rgg-like regulator ElrR activates expression of the elrA operon 10.1128/JB.00121-13

Mortality in patients with early- or late-onset candidaemia 10.1093/jac/dks480

MALDI-TOF mass spectrometry in the clinical mycology laboratory: Identification of fungi and beyond 10.1586/epr.13.8

HPV infection in squamous cell carcinomas arising from different mucosal sites of the head and neck region. Is p16 immunohistochemistry a reliable surrogate marker? 10.1038/bjc.2013.55

In vitro interaction between alginate lyase and amphotericin B against aspergillus fumigatus biofilm determined by different methods 10.1128/AAC.01875-12

Antimycotic activity of Myrtus communis L. towards Candida spp. from isolates 10.3855/jidc.2799

The Staphylococcus aureus Opp1 ABC transporter imports nickel and cobalt in zinc-depleted conditions and contributes to virulence 10.1111/mmi.12126

Milbemycins: More than efflux inhibitors for fungal pathogens 10.1128/AAC.02040-12

Typing of nosocomial outbreaks of acinetobacter baumannii by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry 10.1128/JCM.01811-12

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of Mycobacterium tuberculosis 10.1111/2049-632X.12096

Comparative evaluation of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass Spectrometry systems for identification of yeasts of medical importance 10.1128/JCM.00841-13

Why should we monitor (1-3)-β-D-glucan levels during invasive candidiasis? just ask your ophthalmologist! 10.1128/JCM.03090-12

Voriconazole in clinical practice 10.1179/1973947812Y.0000000051

CspR, a cold shock RNA-binding protein involved in the long-term survival and the virulence of enterococcus faecalis 10.1128/JB.01673-12

First case of breakthrough pneumonia due to Aspergillus nomius in a patient with acute myeloid leukemia 10.3109/13693786.2012.660507

Detection of biofilm-grown Aspergillus fumigatus by means of atomic force spectroscopy: Ultrastructural effects of alginate lyase 10.1017/S1431927612001067

The PavA-like fibronectin-binding protein of enterococcus faecalis, EfbA, Is important for virulence in a mouse model of ascending urinary tract infection 10.1093/infdis/jis440

Rhodococcus equi's extreme resistance to hydrogen peroxide is mainly conferred by one of its four catalase genes 10.1371/journal.pone.0042396

Review article: Biofilm formation by Helicobacter pylori as a target for eradication of resistant infection 10.1111/j.1365-2036.2012.05165.x

AsrR Is an Oxidative Stress Sensing Regulator Modulating Enterococcus faecium Opportunistic Traits, Antimicrobial Resistance, and Pathogenicity 10.1371/journal.ppat.1002834

Evaluation of the new NucliSENS EasyQ KPC test for rapid detection of Klebsiella pneumoniae carbapenemase genes (blaKPC) 10.1128/JCM.00284-12

Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species 10.1128/JCM.00224-12

Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for discrimination between molecular types of Cryptococcus neoformans and Cryptococcus gattii 10.1128/JCM.00737-12

Species identification of Aspergillus, Fusarium and Mucorales with direct surface analysis by matrix-assisted laser desorption ionization time-of-flight mass spectrometry 10.1111/j.1469-0691.2011.03599.x

Involvement of peptidylprolyl cis/trans isomerases in Enterococcus faecalis virulence 10.1128/IAI.06251-11

Antifungal peptides at membrane interaction 10.1016/j.ejmech.2012.02.037

In vitro activities of amphotericin B and AmBisome against Aspergillus isolates recovered from Italian patients treated for haematological malignancies 10.1016/j.ijantimicag.2012.01.013

Galactomannan testing might be useful for early diagnosis of fusariosis 10.1016/j.diagmicrobio.2011.12.009

Risk factors and outcomes of candidemia caused by biofilm-forming isolates in a tertiary care hospital 10.1371/journal.pone.0033705

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Comparative effects of micafungin, caspofungin, and anidulafungin against a difficult-to-treat fungal opportunistic pathogen, Candida glabrata 10.1128/AAC.05872-11

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Fungicidal activity of the human peptide hepcidin 20 alone or in combination with other antifungals against Candida glabrata isolates 10.1016/j.peptides.2011.10.012

Diagnosis of invasive aspergillosis by a commercial real-time PCR assay for Aspergillus DNA in bronchoalveolar lavage fluid samples from high-risk patients compared to a galactomannan enzyme immunoassay 10.1128/JCM.05026-11

Early diagnosis of candidemia in intensive care unit patients with sepsis: a prospective comparison of (1→3)-β-D-glucan assay, Candida score, and colonization index. 10.1186/cc10507

SlyA is a transcriptional regulator involved in the virulence of Enterococcus faecalis 10.1128/IAI.01132-10

Uncommon Neosartorya udagawae fungus as a causative agent of severe corneal infection 10.1128/JCM.00134-11

Role of the (Mn)superoxide dismutase of Enterococcus faecalis in the in vitro interaction with microglia 10.1099/mic.0.047381-0

In vitro activities of anidulafungin and other antifungal agents against biofilms formed by clinical isolates of different Candida and Aspergillus species 10.1128/AAC.01569-10

Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A 10.1186/1471-2180-11-97

Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice 10.1128/AAC.01271-10

Analysis of heat-induced changes in protein expression of Stenotrophomonas maltophilia K279a reveals a role for GroEL in the host-temperature adaptation 10.1016/j.ijmm.2010.10.001

Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata 10.1371/journal.pone.0017589

Update on the laboratory diagnosis of invasive fungal infections 10.4084/MJHID.2011.002

Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to rpoB gene sequencing for species identification of bloodstream infection staphylococcal isolates 10.1111/j.1469-0691.2010.03181.x

The use of mannan antigen and anti-mannan antibodies in the diagnosis of invasive candidiasis: Recommendations from the Third European Conference on Infections in Leukemia 10.1186/cc9365

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A nickel ABC-transporter of Staphylococcus aureus is involved in urinary tract infection 10.1111/j.1365-2958.2010.07416.x

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Early mannan detection in bronchoalveolar lavage fluid with preemptive treatment reduces the incidence of invasive Candida infections in preterm infants 10.1097/INF.0b013e3181da866d

A nickel ABC-transporter of Staphylococcus aureus is involved in urinary tract infection 10.1111/j.1365-2958.2010.07287.x

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The extracytoplasmic function sigma factor SigV plays a key role in the original model of lysozyme resistance and virulence of Enterococcus faecalis 10.1371/journal.pone.0009658

Caspofungin for the treatment of candidaemia in patients with haematological malignancies 10.1111/j.1469-0691.2009.02832.x

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Resistin regulates human choriocarcinoma cell invasive behaviour and endothelial cell angiogenic processes 10.1677/joe.1.06610

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Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance 10.1128/AAC.49.2.668-679.2005

In vitro activity of bergamot natural essence and furocoumarin-free and distilled extracts, and their associations with boric acid, against clinical yeast isolates 10.1093/jac/dkh503

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Use of the VITEK 2 system for rapid identification of clinical isolates of staphylococci from bloodstream infections 10.1128/JCM.41.9.4259-4263.2003

Comparison of real-time PCR, conventional PCR, and galactomannan antigen detection by enzyme-linked immunosorbent assay using bronchoalveolar lavage fluid samples from hematology patients for diagnosis of invasive pulmonary aspergillosis 10.1128/JCM.41.8.3922-3925.2003

Characterization of clinical isolates of Enterobacteriaceae from Italy by the BD Phoenix extended-spectrum β-lactamase detection method 10.1128/JCM.41.4.1463-1468.2003

Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole 10.1046/j.1365-2958.2003.03281.x

Early detection of negative BACTEC MGIT 960 cultures by PCR-reverse cross-blot hybridization assay 10.1128/JCM.40.9.3499-3501.2002

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Fatal pulmonary infection due to multidrug-resistant Mycobacterium abscessus in a patient with cystic fibrosis 10.1128/JCM.39.2.816-819.2001

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Alternaria is an infrequent cause of keratitis: A case report and review of the literature 10.1097/ICL.0000000000000012

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Different effects of matrix degrading enzymes towards biofilms formed by E. faecalis and E. faecium clinical isolates 10.1016/j.colsurfb.2017.07.010

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Subinhibitory Concentrations of Ciprofloxacin Enhance Antimicrobial Resistance and Pathogenicity of Enterococcus faecium 10.1128/aac.02763-16

Understanding cutaneous tuberculosis: two clinical cases 10.1099/jmmcr.0.005070

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Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound 10.1021/acs.jmedchem.6b00018

Identification of Molds by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry 10.1128/jcm.01640-16

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Biofilm’s Role in Chronic Cholesteatomatous Otitis Media 10.1177/0194599816630548

A cluster ofGeotrichum clavatum(Saprochaete clavata) infection in haematological patients: a first Italian report and review of literature 10.1111/myc.12508

Towards a “Green” Antimicrobial Therapy: Study of Graphene Nanosheets Interaction with Human Pathogens 10.1016/j.bpj.2015.11.2834

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Biomimetic antimicrobial cloak by graphene-oxide agar hydrogel 10.1038/s41598-016-0010-7

Invasive fungal infections in chronic lymphoproliferative disorders: a monocentric retrospective study 10.3324/haematol.2016.151837

PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2 10.1371/journal.pone.0150800

Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization 10.1128/msphere.00065-15

Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents 10.1073/pnas.1522987113

(1,3)-β-d-Glucan-based antifungal treatment in critically ill adults at high risk of candidaemia: an observational study 10.1093/jac/dkw112

3-(Benzodioxan-2-ylmethoxy)-2,6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and Mtb cell division 10.1016/j.ejmech.2016.03.068

Impact evaluation of a Critical Pathway for patients with Clostridium difficile infection: A pre-post analysis in a Third Level Referral Center 10.1016/j.ijid.2019.01.025

Antimicrobial susceptibility testing of pathogens isolated from blood culture: a performance comparison of Accelerate Pheno™ and VITEK® 2 systems with the broth microdilution method 10.1093/jac/dky532

Fish-derived antimicrobial peptides: Activity of a chionodracine mutant against bacterial models and human bacterial pathogens 10.1016/j.dci.2019.02.012

Comparable serum and plasma 1,3-β-d-glucan values obtained using the wako β-glucan test in patients with probable or proven fungal diseases 10.1128/JCM.00149-19

In Vitro Activity of Fenticonazole against Candida and Bacterial Vaginitis Isolates Determined by Mono- or Dual-Species Testing Assays 10.1128/AAC.02693-18

Simplified Testing Method for Direct Detection of Carbapenemase-Producing Organisms from Positive Blood Cultures Using the NG-Test Carba 5 Assay 10.1128/AAC.00550-19

Efficient Inactivation of Clinically Relevant Antimicrobial Drug Concentrations by BacT/Alert or Bactec Resin-Containing Media in Simulated Adult Blood Cultures 10.1128/AAC.00420-19

Conjugation of different immunogenic enterococcal vaccine target antigens leads to extended strain coverage 10.1093/infdis/jiz357

Antibiofilm Activity of Three Different Irrigation Techniques: An in Vitro Study 10.3390/antibiotics8030112

A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor 10.3390/cancers11060848

Off-site versus on-site clinical microbiology laboratory: a 2-year comparison study of blood culture result reporting 10.1016/j.cmi.2019.06.021

Diagnosis and treatment of invasive fungal infections: looking ahead 10.1093/jac/dkz041

Collaborative national multicenter for the identification of conversion factors from copies/mL to international units/mL for the normalization of HCMV DNA load 10.1016/j.diagmicrobio.2019.05.012

Direct use of eazyplex^® SuperBug CRE assay from positive blood cultures in conjunction with inpatient infectious disease consulting for timely appropriate antimicrobial therapy in Escherichia coli and Klebsiella pneumoniae bloodstream infections

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The role of procalcitonin outside of the Intensive Care Unit (ICU): a multidisciplinary approach 10.26355/eurrev_201904_17579

Antifungal properties of silver coating on tumour endoprostheses: an in vitro study 10.26355/eurrev_201904_17499

Diabetic foot infections: a comprehensive overview 10.26355/eurrev_201904_17471

Anti-tumor necrosis factor α therapy associates to type 17 helper T lymphocytes immunological shift and significant microbial changes in dextran sodium sulphate colitis 10.3748/wjg.v25.i12.1465

ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients 10.1007/s00134-019-05599-w

In vitro Evaluation of BACT/ALERT® VIRTUO®, BACT/ALERT 3D®, and BACTEC™ FX Automated Blood Culture Systems for Detection of Microbial Pathogens Using Simulated Human Blood Samples 10.3389/fmicb.2019.00221

Educational interventions alone and combined with port protector reduce the rate of central venous catheter infection and colonization in respiratory semi-intensive care unit 10.1186/s12879-019-3848-z

Clostridium difficile: trend in an Italian Tertiary Care Hospital during fifteen years, 2002-2016 10.23736/S0026-4806.18.05740-3

Evaluation of Mass Spectrometry-Based Detection of Panfungal Serum Disaccharide for Diagnosis of Invasive Fungal Infections: Results from a Collaborative Study Involving Six European Clinical Centers 10.1128/jcm.01867-18

Use of Aspergillus fumigatus real-time PCR in bronchoalveolar lavage samples (BAL) for diagnosis of invasive aspergillosis, including azole-resistant cases, in high risk haematology patients: the need for a combined use with galactomannan 10.1093/mmy/myz002

ESCMID-EUCIC clinical guidelines on decolonization of multidrug-resistant Gram-negative bacteria carriers 10.1016/j.cmi.2019.01.005

Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Methods 10.1128/aac.01651-18

How are trainees in clinical microbiology and infectious diseases supervised in Europe? An international cross-sectional questionnaire survey by the Trainee Association of ESCMID 10.1007/s10096-018-3386-4

PE_PGRS3 of Mycobacterium tuberculosis is specifically expressed at low phosphate concentration, and its arginine-rich C-terminal domain mediates adhesion and persistence in host tissues when expressed in Mycobacterium smegmatis 10.1111/cmi.12952

ESCMID white paper: a guide on ESCMID guidance documents 10.1016/j.cmi.2018.08.005

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms 10.15698/mic2018.07.638

Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes 10.1016/j.cmi.2018.06.020

Randomised clinical trial: faecal microbiota transplantation by colonoscopy plus vancomycin for the treatment of severe refractory Clostridium difficile infection—single versus multiple infusions 10.1111/apt.14816

Biofilm in voice prosthesis: A prospective cohort study and laboratory tests using sonication and SEM analysis 10.1111/coa.13141

Curcumin-loaded graphene oxide flakes as an effective antibacterial system against methicillin-resistant staphylococcus aureus 10.1098/rsfs.2017.0059

Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline 10.1016/j.cmi.2018.01.002

Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of cyp51A Mutations on Estimation of Epidemiological Cutoff Values 10.1128/aac.01916-17

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis 10.1016/s1473-3099(17)30753-3

Microbiologic and clinical characteristics of biofilm-forming Candida parapsilosis isolates associated with fungaemia and their impact on mortality 10.1016/j.cmi.2017.11.005

A 72-h intervention for improvement of the rate of optimal antibiotic therapy in patients with bloodstream infections 10.1007/s10096-017-3117-2

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Cooperating to improve healthcare in Arab countries 10.4415/ANN_17_04_09

Importance of Resolving Fungal Nomenclature: the Case of Multiple Pathogenic Species in the Cryptococcus Genus 10.1128/msphere.00238-17

Combined use of serum (1,3)-β-d-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units 10.1186/s13054-017-1763-5

Predictors of failure after single faecal microbiota transplantation in patients with recurrent Clostridium difficile infection: results from a 3-year cohort study: authors' reply 10.1016/j.cmi.2017.05.005

Personal life and working conditions of trainees and young specialists in clinical microbiology and infectious diseases in Europe: a questionnaire survey 10.1007/s10096-017-2937-4

European consensus conference on faecal microbiota transplantation in clinical practice 10.1136/gutjnl-2016-313017

Predictors of failure after single faecal microbiota transplantation in patients with recurrent Clostridium difficile infection: results from a 3-year, single-centre cohort study 10.1016/j.cmi.2016.12.025

Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method 10.1128/aac.01792-16

A large survey among European trainees in clinical microbiology and infectious disease on training systems and training adequacy: identifying the gaps and suggesting improvements 10.1007/s10096-016-2791-9

Effects of proton pump inhibitors on the gastric mucosa-associated microbiota in dyspeptic patients 10.1128/AEM.01437-16

Nursing home residence is associated with spread of Clostridium difficile ribotype 027 in central Italy 10.1016/j.jhin.2016.06.024

In vitro effect of clarithromycin and alginate lyase against helicobacter pylori biofilm 10.1002/btpr.2339

Predictors of choice of initial antifungal treatment in intraabdominal candidiasis 10.1016/j.cmi.2016.06.005

Diagnostic of Fungal Infections Related to Biofilms 10.1007/5584_2016_9

Efficacy and Mechanisms of Action of Fecal Microbiota Transplantation in Ulcerative Colitis: Pitfalls and Promises From a First Meta-Analysis 10.1016/j.transproceed.2015.12.040

Detection of Rare G3P[19] Group A Rotavirus in Human Patient, Italy 10.3201/2011.131699

An antibody reactivity-based assay for diagnosis of invasive candidiasis using protein array. 10.1177/039463201402700310

Gelatin tannate ameliorates acute colitis in mice by reinforcing mucus layer and modulating gut microbiota composition: Emerging role for 'gut barrier protectors' in IBD? 10.1177/2050640614520867

Risks of "blind" automated identification systems in medical microbiology. 10.1128/JCM.02032-13

Pulmonary malacoplakia at early stage: use of polymerase chain reaction for detection of Rhodococcus equi. 10.1177/039463201202500316

Biofilm production by Candida isolates from a survey of invasive fungal infections in Italian intensive care units. 10.1179/1120009x12z.00000000014

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Usefulness of Antifungal Reference In Vitro Susceptibility Tests as a Guide in Therapeutic Management 10.1007/s12281-019-0336-2

Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes 10.1016/j.cmi.2014.09.017

Erratum: Biomimetic antimicrobial cloak by graphene-oxide agar hydrogel 10.1038/s41598-017-00063-5

Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project 10.1111/myc.12869

Molecular detection of resistance to azole components 10.1007/978-1-4939-6515-1_24

Molecular detection of resistance to echinocandins 10.1007/978-1-4939-6515-1_23

Tuberculosis in migrants from 106 countries to Italy, 2008-2014 10.1183/13993003.01844-2015

Nonlinear optics, optomechanics, and antibacterial coating by graphene oxide 10.1117/12.2250513

Optical supercavitation in graphene-oxide hydrogel for antimicrobial cloaks 10.1364/NLO.2017.NM2B.1

‘Being a parent at ECCMID 2019’ – ESCMID's reply 10.1016/j.cmi.2019.05.018

First bloodstream infection caused by Prevotella copri in a heart failure elderly patient with Prevotella-dominated gut microbiota: a case report 10.1186/s13099-019-0325-6

Different detection capabilities by mycological media for Candida isolates from mono- or dual-species cultures 10.1101/862078

In vitro characterization, ADME analysis, histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains 10.1016/j.ijantimicag.2019.105865

Looking for appropriateness in the cure of mixed vaginitis: the role of fenticonazole as an empiric treatment 10.2217/fmb-2019-0189

Fecal Microbiota Transplantation: A Potential Tool for Treatment of Human Female Reproductive Tract Diseases 10.3389/fimmu.2019.02653

Development of a Multiplex PCR Platform for the Rapid Detection of Bacteria, Antibiotic Resistance, and Candida in Human Blood Samples 10.3389/fcimb.2019.00389

Rapid molecular tests for detection of antimicrobial resistance determinants in Gram-negative organisms from positive blood cultures: a systematic review and meta-analysis 10.1016/j.cmi.2019.11.009

Laboratory handling practice for faecal microbiota transplantation 10.1111/jam.14522

Incidence of Bloodstream Infections, Length of Hospital Stay, and Survival in Patients With Recurrent Clostridioides difficile Infection Treated With Fecal Microbiota Transplantation or Antibiotics 10.7326/m18-3635

BIOF–HILO Assay: A New MALDI–TOF Mass Spectrometry Based Method for Discriminating Between High- and Low-Biofilm-Producing Candida parapsilosis Isolates 10.3389/fmicb.2019.02046

Serum interleukin-6 and endotoxin levels and their relationship with fatigue and depressive symptoms in patients on chronic haemodialysis 10.1016/j.cyto.2019.154823

The importance of rapid diagnosis for multidrug-resistant Candida: an interview with Maurizio Sanguinetti 10.2217/fmb-2019-0198

Graphene Oxide Coatings as Tools to Prevent Microbial Biofilm Formation on Medical Device. 10.1007/5584_2019_434

Prenatal valacyclovir treatment of fetal citomegalovirus infection: A case series. 10.1016/j.jinf.2019.08.015

Different detection capabilities by mycological media for Candida isolates from mono- or dual-species cultures 10.1371/journal.pone.0226467

Nasopharyngeal Microbiota Profiling of SARS-CoV-2 Infected Patients 10.21203/rs.3.rs-27326/v1

Accuracy of QuantiFERON-TB Gold Plus Test for Diagnosis of Mycobacterium tuberculosis Infection in Children 10.1128/JCM.00272-20

Viral RNA load quantification as helpful tool to arbitrate SARS–CoV-2 detection results in respiratory samples 10.21203/rs.3.rs-34028/v1

Confirmed or Unconfirmed Cases of 2019 Novel Coronavirus Pneumonia in Italian Patients: A Retrospective Analysis of Clinical Features 10.21203/rs.3.rs-35575/v1

Nasopharyngeal Microbiota Profiling of SARS-CoV-2 Infected Patients 10.21203/rs.3.rs-27326/v2

Bordetella pertussis DNA detected in a tracheostomized child blood before seroconversion 10.1007/s10096-020-03988-4

Nasopharyngeal Microbiota Profiling of SARS-CoV-2 Infected Patients 10.1186/s12575-020-00131-7

Comparative performance evaluation of Wako β-glucan test and Fungitell assay for the diagnosis of invasive fungal diseases 10.1371/journal.pone.0236095

Evaluation and cost estimation of laboratory test overuse in 43 commonly ordered parameters through a Computerized Clinical Decision Support System (CCDSS) in a large university hospital 10.1371/journal.pone.0237159

Evaluation of three commercial assays for SARS-CoV-2 molecular detection in upper respiratory tract samples 10.1007/s10096-020-04025-0

Update on Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Identification of Filamentous Fungi 10.1128/JCM.01263-20

Confirmed or unconfirmed cases of 2019 novel coronavirus pneumonia in Italian patients: a retrospective analysis of clinical features 10.21203/rs.3.rs-35575/v2

Confirmed or unconfirmed cases of 2019 novel coronavirus pneumonia in Italian patients: a retrospective analysis of clinical features 10.1186/s12879-020-05504-7

Confirmed or unconfirmed cases of 2019 novel coronavirus pneumonia in Italian patients: a retrospective analysis of clinical features 10.21203/rs.3.rs-35575/v3

New Data on the In Vitro Activity of Fenticonazole against Fluconazole-Resistant Candida Species 10.1128/AAC.01459-20

Assessment of SARS-CoV-2 RNA Test Results Among Patients Who Recovered From COVID-19 With Prior Negative Results. 10.1001/jamainternmed.2020.7570

EUCAST rapid antimicrobial susceptibility testing of blood cultures positive for Escherichia coli or Klebsiella pneumoniae: experience of three laboratories in Italy 10.1093/jac/dkaa554

Identification and molecular characterization of Subramaniula asteroides causing human fungal keratitis: a case report 10.1186/s12879-021-05768-7

Is the Antimicrobial Activity of Hydrolates Lower than That of Essential Oils? 10.3390/antibiotics10010088

Comparing BioFire FilmArray BCID2 and BCID Panels for Direct Detection of Bacterial Pathogens and Antimicrobial Resistance Genes from Positive Blood Cultures 10.1128/JCM.03163-20

Genetic and Phenotypic Characterization of in-Host Developed Azole-Resistant Aspergillus flavus Isolates 10.3390/jof7030164

COVID-19 Rapid Antigen Test as Screening Strategy at Points of Entry: Experience in Lazio Region, Central Italy, August–October 2020 10.3390/biom11030425

Phytocomplex Influences Antimicrobial and Health Properties of Concentrated Glycerine Macerates 10.3390/antibiotics9120858

Origanum vulgare Essential Oil vs. a Commercial Mixture of Essential Oils: In Vitro Effectiveness on Salmonella spp. from Poultry and Swine Intensive Livestock 10.3390/antibiotics9110763

Antimicrobial and Antibiofilm Properties of Graphene Oxide on Enterococcus faecalis 10.3390/antibiotics9100692

Molecular Mechanisms, Epidemiology, and Clinical Importance of β-Lactam Resistance in Enterobacteriaceae 10.3390/ijms21145090

Graphene Oxide-Linezolid Combination as Potential New Anti-Tuberculosis Treatment 10.3390/nano10081431

Day 10 Post-Prescription Audit Optimizes Antibiotic Therapy in Patients with Bloodstream Infections 10.3390/antibiotics9080437

Potent In Vitro Activity of Citrus aurantium Essential Oil and Vitis vinifera Hydrolate Against Gut Yeast Isolates from Irritable Bowel Syndrome Patients—The Right Mix for Potential Therapeutic Use 10.3390/nu12051329

Characterizing Peri-Implant and Sub-Gingival Microbiota through Culturomics. First Isolation of Some Species in the Oral Cavity. A Pilot Study 10.3390/pathogens9050365

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells 10.1080/21505594.2021.1897247

Saliva Is a Valid Alternative to Nasopharyngeal Swab in Chemiluminescence-Based Assay for Detection of SARS-CoV-2 Antigen 10.3390/jcm10071471

Risk Factors for Mortality in Adult COVID-19 Patients Who Develop Bloodstream Infections Mostly Caused by Antimicrobial-Resistant Organisms: Analysis at a Large Teaching Hospital in Italy 10.3390/jcm10081752

Hand hygiene and facemask use to prevent droplet-transmitted viral diseases during air travel: a systematic literature review 10.1186/s12889-021-10814-9

Direct Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Testing from Positive Blood Cultures for Rapid Identification of Bloodstream Infection-Causing Anaerobic Bacteria 10.1128/JCM.00521-21

Seroprevalence of SARS-CoV-2 Antibodies in HIV-Infected Patients in Rome, Italy during the COVID-19 Outbreak 10.3390/diagnostics11071154

Post-Prescription Audit Plus Beta-D-Glucan Assessment Decrease Echinocandin Use in People with Suspected Invasive Candidiasis 10.3390/medicina57070656

SARS-CoV-2 Antigen Detection to Expand Testing Capacity for COVID-19: Results from a Hospital Emergency Department Testing Site 10.3390/diagnostics11071211

Direct Testing for KPC-Mediated Carbapenem Resistance from Blood Samples Using a T2 Magnetic Resonance Based Assay 10.3390/antibiotics10080950

A New PCR-Based Assay for Testing Bronchoalveolar Lavage Fluid Samples from Patients with Suspected Pneumocystis jirovecii Pneumonia 10.3390/jof7090681

RICCARDO MANGANELLI

MANGANELLI RICCARDO

ORCID: 0000-0003-0940-7336

The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053 10.1074/jbc.M115.677039

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG 10.1016/j.chembiol.2015.05.016

Whole cell screen based identification of spiropiperidines with potent antitubercular properties 10.1016/j.bmcl.2015.05.087

Mycobacterium tuberculosis virulence: Insights and impact on vaccine development 10.2217/fmb.15.26

The essential role of SepF in mycobacterial division 10.1111/mmi.13050

Improved protection in guinea pigs after vaccination with a recombinant BCG expressing MPT64 on its surface 10.1016/j.trivac.2015.03.003

Correction: Mycobacterium tuberculosis requires the ECF sigma factor SigE to arrest phagosome maturation 10.1371/journal.pone.0115990

Impact of protein domains on PE-PGRS30 polar localization in Mycobacteria 10.1371/journal.pone.0112482

Mycobacterium tuberculosis requires the ECF sigma factor SigE to arrest phagosome maturation 10.1371/journal.pone.0108893

Homologous prime boosting based on intranasal delivery of non-pathogenic invasive Escherichia coli expressing MPT64, decreases Mycobacterium tuberculosis dissemination 10.1016/j.vaccine.2014.05.060

Erratum: The ESX-3 secretion system is necessary for iron and zinc homeostasis in mycobacterium tuberculosis (PLoS ONE (2014) 9:1) 10.1371/annotation/56401af3-74aa-4c4f-882c-06481b29aa94

Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants 10.1111/mmi.12546

Erratum to The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo [Journal of Bacteriology, 196, 19, (2014) 3441-3451] DOI: 10.1128/JB.02332-14 10.1128/JB.02332-14

Four year longitudinal study of Mycobacterium tuberculosis complex isolates in a region of North-Eastern Italy 10.1016/j.meegid.2014.05.004

The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo 10.1128/JB.01346-13

Critical research concepts in tuberculosis vaccine development 10.1111/1469-0691.12460

Genomic comparative analysis and gene function prediction in infectious diseases: Application to the investigation of a meningitis outbreak 10.1186/1471-2334-13-554

The ESX-3 Secretion System Is Necessary for Iron and Zinc Homeostasis in Mycobacterium tuberculosis 10.1371/journal.pone.0078351

GarA is an essential regulator of metabolism in mycobacterium tuberculosis 10.1111/mmi.12368

The PPE Domain of PPE17 Is Responsible for Its Surface Localization and Can Be Used to Express Heterologous Proteins on the Mycobacterial Surface 10.1371/journal.pone.0057517

Exploiting the mycobacterial cell wall to design improved vaccines against tuberculosis 10.3855/jidc.3114

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of Mycobacterium tuberculosis 10.1111/2049-632X.12096

WhiB5, a transcriptional regulator that contributes to mycobacterium tuberculosis virulence and reactivation 10.1128/IAI.06328-11

Functional and genetic characterization of the tap efflux pump in Mycobacterium bovis BCG 10.1128/AAC.05946-11

PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis 10.1111/j.1462-5822.2011.01721.x

Functional dissection of the pe domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall 10.1371/journal.pone.0027713

PPE-MPTR genes are differentially expressed by Mycobacterium tuberculosis in vivo 10.1016/j.tube.2011.08.002

Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway 10.1074/jbc.M110.204966

Molecular epidemiology of Enterococcus faecium isolates from an Italian hospital 10.1007/s15010-011-0086-8

Surface expression of MPT64 as a fusion with the PE domain of PE-PGRS33 enhances Mycobacterium bovis BCG protective activity against Mycobacterium tuberculosis in mice 10.1128/IAI.00267-10

Xer site-specific recombination, an efficient tool to introduce unmarked deletions into mycobacteria 10.1128/AEM.00382-10

Immunogenicity and protection induced by a Mycobacterium tuberculosis sigE mutant in a BALB/c mouse model of progressive pulmonary tuberculosis 10.1128/IAI.00023-10

Development of a repressible mycobacterial promoter system based on two transcriptional repressors 10.1093/nar/gkq235

Characterisation of qnr plasmid-mediated quinolone resistance in Enterobacteriaceae from Italy: Association of the qnrB19 allele with the integron element ISCR1 in Escherichia coli 10.1016/j.ijantimicag.2010.02.015

An integrated regulatory network including two positive feedback loops to modulate the activity of σ^e in mycobacteria 10.1111/j.1365-2958.2009.07009.x

Characterization of a Mycobacterium tuberculosis ESX-3 conditional mutant: Essentiality and rescue by iron and zinc 10.1128/JB.00756-09

The Mycobacterium tuberculosis sigma factor σ^B is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth 10.1128/JB.00510-09

Global transcriptional response to vancomycin in Mycobacterium tuberculosis 10.1099/mic.0.024802-0

News from the antituberculosis front at two recent European meetings 10.1007/s11274-009-0056-9

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 10.1016/j.tube.2008.08.003

Use of DNA microarrays to study global patterns of gene expression 10.1007/978-1-59745-207-6_7

SigF controls carotenoid pigment production and affects transformation efficiency and hydrogen peroxide sensitivity in Mycobacterium smegmatis 10.1128/JB.00714-08

Assessment of the lightcycler PCR assay for diagnosis of invasive aspergillosis in paediatric patients with onco-haematological diseases 10.1111/j.1439-0507.2008.01512.x

Evidence of complex transcriptional, translational, and posttranslational regulation of the extracytoplasmic function sigma factor σ^E in Mycobacterium tuberculosis 10.1128/JB.00622-08

Intranasal delivery of DNA encoding antigens of Mycobacterium tuberculosis by non-pathogenic invasive Escherichia coli 10.1016/j.vaccine.2008.02.023

PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall 10.1111/j.1365-2958.2007.06023.x

Erratum: Antibiotic-resistant invasive pneumococcal clones in Italy (Journal of Clinical Microbiology (2007) 45,2, (306-312)) 10.1128/JCM.01338-07

Polyphosphate and stress response in mycobacteria 10.1111/j.1365-2958.2007.05819.x

Erratum: Global analysis of the Mycobacterium tuberculosis zur (FurB) regulon (Journal of Bacteriology (2007) 189, 3, (730-740)) 10.1128/JB.00593-07

Antibiotic-resistant invasive pneumococcal clones in Italy 10.1128/JCM.01229-06

Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 10.1128/JB.01190-06

The σ factors of Mycobacterium tuberculosis 10.1111/j.1574-6976.2006.00040.x

Molecular investigation of an outbreak of multidrug-resistant Acinetobacter baumannii, with characterisation of class 1 integrons 10.1016/j.ijantimicag.2006.04.016

Infection of human dendritic cells with a Mycobacterium tuberculosis sigE mutant stimulates production of high levels of interleukin-10 but low levels of CXCL10: Impact on the T-cell response 10.1128/IAI.01687-05

Posttranslational regulation of Mycobacterium tuberculosis extracytoplasmic-function sigma factor σ^L and roles in virulence and in global regulation of gene expression 10.1128/IAI.74.4.2457-2461.2006

Engineered E. coli delivers therapeutic genes to the colonic mucosa 10.1038/sj.gt.3302493

Erratum: Engineered E. coli delivers therapeutic genes to the colonic mucosa (Gene Therapy (2005) vol. 12 (1070-1078) 10.1038/sj.gt.3302493) 10.1038/sj.gt.3302574

Selection and characterization of a promoter for expression of single-copy recombinant genes in Gram-positive bacteria 10.1186/1472-6750-5-3

The Extra Cytoplasmic Function Sigma Factor σ^E Is Essential for Mycobacterium tuberculosis Virulence in Mice 10.1128/IAI.72.5.3038-3041.2004

Erratum: σ Factors and Global Gene Regulation in Mycobacterium tuberculosis (Journal of Bacteriology (2004) 186, 4 (895-902)) 10.1128/JB.186.8.2516.2004

σ Factors and Global Gene Regulation in Mycobacterium tuberculosis 10.1128/JB.186.4.895-902.2004

Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients 10.1073/pnas.2436197100

PEGylation of the antimicrobial peptide nisin A: Problems and perspectives 10.1016/S0014-827X(02)01301-0

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis 10.1046/j.1365-2958.2002.03009.x

Role of the extracytoplasmic-function σ factor σ^H in Mycobacterium tuberculosis global gene expression 10.1046/j.1365-2958.2002.03005.x

Mycobacterium tuberculosis genes induced during infection of human macrophages? 10.1128/IAI.70.6.2787-2795.2002

The Mycobacterium tuberculosis ECF sigma factor σ^E: Role in global gene expression and survival in macrophages 10.1046/j.1365-2958.2001.02525.x

Immunogenicity of the B monomer of Escherichia coli heat-labile toxin expressed on the surface of Streptococcus gordonii 10.1128/IAI.68.2.760-766.2000

Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis 10.1046/j.1365-2958.1999.01212.x

Extra and intracellular expression of Mycobacterium tuberculosis genes 10.1054/tuld.1998.0010

Insertion vectors for construction of recombinant conjugative transposons in Bacillus subtilis and Enterococcus faecalis 10.1016/S0378-1097(98)00449-2

Recombinant Gram-positive bacteria as vehicles of vaccine antigens 10.1016/S1387-2656(08)70038-3

The joint of Tn916 circular intermediates is a homoduplex in Enterococcus faecalis 10.1006/plas.1997.1300

Characterization of conjugative transposon Tn5251 of Streptococcus pneumoniae 10.1016/0378-1097(95)00455-6

Dosage of tn916 circular intermediates in enterococcus faecalis 10.1006/plas.1995.1032

Immunization of mice by oral colonization with live recombinant commensal streptococci 10.1016/0264-410X(94)00060-Z

Human T-helper cell recognition of an immunodominant epitope of HIV-1 gp120 expressed on the surface of Streptococcus gordonii 10.1016/0264-410X(94)90175-9

Expression of M6 protein gene of Streptococcus pyogenes in Streptococcus gordonii after chromosomal integration and transcriptional fusion 10.1016/0923-2508(92)90090-B

Method and parameters for genetic transformation of Streptococcus sanguis challis 10.1016/0923-2508(90)90060-4

Virological testing of cerebrospinal fluid in children aged less than 14 years with a suspected central nervous system infection: A retrospective study on 304 consecutive children from January 2012 to May 2015 10.1016/j.ejpn.2016.04.002

Sigma factors: Key molecules in Mycobacterium tuberculosis physiology and virulence 10.1128/microbiolspec. MGM2-0007-2013

Viral infections of the central nervous system in elderly patients: A retrospective study 10.1016/j.ijid.2016.01.012

Protecting from Envelope Stress: Variations on the Phage-Shock-Protein Theme 10.1016/j.tim.2016.10.001

PE-PGRS33 contributes to Mycobacterium tuberculosis entry in macrophages through interaction with TLR2 10.1371/journal.pone.0150800

Erratum: Protecting from Envelope Stress: Variations on the Phage-Shock-Protein Theme: Trends in Microbiology (2017) 25(3) (205–216) (S0966842X16301615) (10.1016/j.tim.2016.10.001)) 10.1016/j.tim.2016.11.010

Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression 10.1038/srep43495

Micrococcin P1 – A bactericidal thiopeptide active against Mycobacterium tuberculosis 10.1016/j.tube.2016.07.011

Tuberculosis in migrants from 106 countries to Italy, 2008-2014 10.1183/13993003.01844-2015

Evaluation of new antibiotic cocktails against contaminating bacteria found in allograft tissues 10.1007/s10561-016-9581-6

Inorganic phosphate limitation modulates capsular polysaccharide composition in mycobacteria 10.1074/jbc.M116.722454

Mycobacterium tuberculosis sigE mutant ST28 used as a vaccine induces protective immunity in the guinea pig model 10.1016/j.tube.2017.07.009

The alternative sigma factors SigE and SigB are involved in tolerance and persistence to antitubercular drugs 10.1128/AAC.01596-17

Impact of pe_pgrs33 gene polymorphisms on mycobacterium tuberculosis infection and pathogenesis 10.3389/fcimb.2017.00137

Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE 10.1038/s41598-019-41183-4

Improving the stability of the TetR/Pip-OFF mycobacterial repressible promoter system 10.1038/s41598-019-42319-2

Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions 10.1038/s41598-017-05867-z

Evaluation of PE PGRS33 as a potential surface target for humoral responses against Mycobacterium tuberculosis 10.1093/femspd/ftx100

A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors 10.1021/acsinfecdis.7b00006

Mycobacterium tuberculosis-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells 10.1371/journal.ppat.1006790

lysX gene is differentially expressed among Mycobacterium tuberculosis strains with different levels of virulence 10.1016/j.tube.2017.07.005

PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis 10.1371/journal.ppat.1006399

Promoter mutagenesis for fine-tuning expression of essential genes in Mycobacterium tuberculosis 10.1111/1751-7915.12875

PE and PPE Genes: A tale of conservation and diversity 10.1007/978-3-319-64371-7_10

The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis 10.1074/jbc.M117.797837

PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interaction 10.1080/21505594.2020.1785815

Tuberculosis-Associated MicroRNAs: From Pathogenesis to Disease Biomarkers 10.3390/cells9102160

Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy 10.1016/j.cellimm.2020.104244

Priscille Brodin

Brodin Priscille

ORCID: 0000-0003-0991-7344

Email: priscille.brodin@inserm.fr

How can nanoparticles contribute to antituberculosis therapy? 10.1016/j.drudis.2017.01.011

Host-directed therapies offer novel opportunities for the fight against tuberculosis 10.1016/j.drudis.2017.05.005

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone 10.3390/toxins9070227

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone 10.3390/toxins9070227 10.3390/toxins9070227.

Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections 10.2217/nnm-2016-0364

Cyclodextrin-based nanocarriers containing a synergic drug combination: a potential formulation for pulmonary administration of antitubercular drugs 10.1016/j.ijpharm.2017.05.030 10.1016/j.ijpharm.2017.05.030.

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism 10.1007/s00401-016-1652-z

Host-directed therapies offer novel opportunities for the fight against tuberculosis 10.1016/j.drudis.2017.05.005 10.1016/j.drudis.2017.05.005.

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria 10.1111/mmi.13535

Impact of pe_ pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis 10.3389/fcimb.2017.00137

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis 10.1111/cmi.12619

Phenotypic assays for Mycobacterium tuberculosis infection 10.1002/cyto.a.23129 10.1002/cyto.a.23129.

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420 10.1126/science.aag1006

A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters 10.1039/c5ob02630j

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro 10.1007/s00705-016-2771-5

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization 10.1016/j.str.2016.07.009

Mycolactone The amazing analgesic mycobacterial toxin 10.1051/medsci/20163202007

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection 10.1038/srep29297

2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 10.1021/cb5007163

Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo 10.1371/journal.ppat.1004650

High content screening in chemical biology: overview and main challenges 10.1051/medsci/20153102016

High-Content Screening Technology Combined with a Human Granuloma Model as a New Approach To Evaluate the Activities of Drugs against Mycobacterium tuberculosis 10.1128/aac.03705-14

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system 10.1016/j.vaccine.2015.03.083

Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro 10.3389/fmicb.2015.00438

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action 10.1128/jvi.01473-15

Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays 10.1007/978-1-4939-2450-9_24

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening 10.3791/51114

Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches 10.1021/jm500422b

Mycobacterial Toxin Induces Analgesia in Buruli Ulcer by Targeting the Angiotensin Pathways 10.1016/j.cell.2014.04.040

Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro 10.1016/j.jff.2014.09.022

A novel specific edge effect correction method for RNA interference screenings 10.1093/bioinformatics/btr648

Discovery of Novel N-Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis 10.1021/jm3003779

Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors 10.1021/jm200825u

The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence 10.1371/journal.pone.0047573

Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis 10.1371/journal.pone.0026675

Ethionamide Boosters: Synthesis, Biological Activity, and Structure-Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors 10.1021/jm200076a

High-content screening in infectious diseases 10.1016/j.cbpa.2011.05.023

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ 10.1099/mic.0.038133-0

High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling 10.1371/journal.ppat.1001100

High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery 10.4155/fmc.10.223

Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting 10.1016/j.biomaterials.2009.09.044

Automated High-Throughput siRNA Transfection in Raw 264.7 Macrophages: A Case Study for Optimization Procedure 10.1177/1087057108328762

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 10.1126/science.1171583

High Content Screening Identifies Decaprenyl-Phosphoribose 2 ' Epimerase as a Target for Intracellular Antimycobacterial Inhibitors 10.1371/journal.ppat.1000645

Systematic Genetic Nomenclature for Type VII Secretion Systems 10.1371/journal.ppat.1000507

Control of M-tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP 10.1371/journal.ppat.0040033

Aquatic insects and transmission of Mycobacterium ulcerans 10.1051/medsci/20072367572

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity 10.1128/jb.00469-07

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis 10.1371/journal.ppat.0030062

Protection against mycobacterium ulcerans lesion development by exposure to aquatic insect saliva 10.1371/journal.pmed.0040064

Support vector machines for automatic detection of tuberculosis bacteria in confocal microscopy images 10.1109/isbi.2007.356794

Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues 10.1016/j.bmc.2006.12.009

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis 10.1128/iai.74.4.2128-2137.2006

Benzofuro 3,2-f 1 benzopyrans: A new class of antitubercular agents 10.1016/j.bmc.2006.03.033

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence 10.1128/iai.74.1.88-98.2006

High frequency of CD4(+) T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection 10.1128/iai.02086-05

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence 10.1128/jb.00631-06

Evaluation of vaccines in the EU TB vaccine cluster using a guinea pig aerosol infection model of tuberculosis 10.1016/j.tube.2004.09.009

Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity 10.1074/jbc.M503515200

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics 10.1099/mic.0.27799-0

Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions 10.1016/j.jmb.2005.05.049

Tuberculosis: from genome to vaccine 10.1586/14760584.4.4.541

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RDI immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6 10.1128/iai.72.4.2170-2176.2004

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens 10.1086/421468

ESAT-6 proteins: protective antigens and virulence factors? 10.1016/j.tim.2004.09.007

Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex 10.1099/mic.0.26662-0

CD8(+)-T-cell responses of mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family 10.1128/iai.71.12.7173-7177.2003

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis 10.1038/nm859

A new evolutionary scenario for the Mycobacterium tuberculosis complex 10.1073/pnas.052548299

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant 10.1128/iai.70.10.5568-5578.2002

Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides 10.1021/bi015732y

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti 10.1046/j.1365-2958.2002.03237.x

6-Oxocytidine containing oligonucleotides inhibit the HIV-1 integrase in vitro 10.1081/ncn-100002322

Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase 10.1021/bi000398b

Inhibition of the human immunodeficiency virus type 1 DNA integration by modified oligonucleotides 10.1023/a:1026631910681

Branched oligonucleotide-intercalator conjugate forming a parallel stranded structure inhibits HIV-1 integrase 10.1016/s0014-5793(99)01350-2

Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides 10.1080/07328319908044831

Optimization of alternate-strand triple helix formation at the 5 '-TpA-3 ' and 5 '-ApT-3 ' junctions 10.1093/nar/27.15.3029

A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus 10.1074/jbc.272.25.16010

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids 10.1073/pnas.1707840114

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton 10.15252/embr.201744371

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton 10.15252/embr.201744371 10.15252/embr.201744371.

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles 10.1038/s41598-017-05453-3

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis 10.1038/s41598-017-11843-4 10.1038/s41598-017-11843-4.

Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays 10.1021/acschembio.7b00091

Host-pathogen systems for early drug discovery against tuberculosis 10.1016/j.mib.2017.11.017 10.1016/j.mib.2017.11.017.

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages 10.1016/j.chom.2017.07.020 10.1016/j.chom.2017.07.020. Epub 2017 Aug 31.

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling 10.1016/j.celrep.2017.08.101 10.1016/j.celrep.2017.08.101.

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids 10.1073/pnas.1707840114 10.1073/pnas.1707840114.

Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry 10.1128/jvi.01982-17

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors 10.1016/j.celrep.2018.03.125

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis 10.1016/j.bioorg.2018.08.025

Proteomics of Mycobacterium infection: Moving towards a Better Understanding of Pathogen-Driven immunomodulation 10.3389/fimmu.2018.00086

Synergy between circular bacteriocin AS-48 and ethambutol against Mycobacterium tuberculosis 10.1128/aac.00359-18

The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 10.1016/j.tube.2018.08.004

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis 10.1038/s41598-017-11843-4

Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs 10.1016/j.ijpharm.2017.05.030

Host-pathogen systems for early drug discovery against tuberculosis 10.1016/j.mib.2017.11.017

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages 10.1016/j.chom.2017.07.020

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling 10.1016/j.celrep.2017.08.101

Phenotypic assays for Mycobacterium tuberculosis infection 10.1002/cyto.a.23129

A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening 10.1002/cyto.a.20627

Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections 10.1002/ppsc.201800360

Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation 10.1074/mcp.RA119.001316

Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters 10.3389/fphar.2019.00378

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis 10.1021/acsnano.8b07902

Mitochondrial Dynamics and Activity in Legionella-Infected Cells 10.1007/978-1-4939-9048-1_13

Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria 10.3389/fmicb.2018.02258

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication 10.1128/jvi.02009-18

A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation 10.1039/C9OB00680J

Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls 10.3390/toxins11090516

Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies. 10.3389/fimmu.2020.569127

Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity. 10.1021/acsinfecdis.9b00277

Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds. 10.1371/journal.pone.0227224

Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis. 10.1016/j.vaccine.2019.11.085

IRG1 controls immunometabolic host response and restricts intracellular Mycobacterium tuberculosis infection 10.1101/761551

Worms' Antimicrobial Peptides. 10.3390/md17090512

T(oo)bAd. 10.1038/s41589-019-0347-x

Theaflavins, polyphenols of black tea, inhibit entry of hepatitis C virus in cell culture. 10.1371/journal.pone.0198226

Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro. 10.3389/fmicb.2015.00488

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. 10.1038/nm.3262

Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. 10.1021/jm300377g

Shortening the drug discovery pipeline: small molecule high content screening for lead discovery in neglected disease. 10.1186/1753-6561-5-s1-p38

Automated HTS/HCS for antivirals using visual HIV full replication assays. 10.1186/1742-4690-6-s2-p82

Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system. 10.4049/jimmunol.174.6.3570

Cell microbiology interview 10.1111/cmi.13288

Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts 10.1099/mgen.0.000505

Gabriele Di Sante

Di Sante Gabriele

ORCID: 0000-0001-6608-3388

https://www.researchgate.net/profile/Gabriele_Di_Sante?ev=hdr_xprf

T cell repertoire in DQ5-positive MuSK-positive myasthenia gravis patients 10.1016/j.jaut.2013.12.007

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of Mycobacterium tuberculosis 10.1111/2049-632X.12096

M tuberculosis in the Adjuvant Modulates Time of Appearance of CNS-Specific Effector T Cells in the Spleen through a Polymorphic Site of TLR2 10.1371/journal.pone.0055819

Intracellular bacteria can cause EAE in SJL mice or modify self-specific T cell repertoire 10.1016/j.jns.2011.08.042

Surface expression of MPT64 as a fusion with the PE domain of PE-PGRS33 enhances Mycobacterium bovis BCG protective activity against Mycobacterium tuberculosis in mice 10.1128/IAI.00267-10

Erbb2 DNA vaccine combined with regulatory T cell deletion enhances antibody response and reveals latent low-avidity T cells: Potential and limits of its therapeutic efficacy 10.4049/jimmunol.0901215

Mycobacterium smegmatis expressing a chimeric protein MPT64-Proteolipid Protein (PLP) 139-151 reorganizes the PLP-specific T cell repertoire favoring a CD8-mediated response and induces a relapsing experimental autoimmune encephalomyelitis 10.4049/jimmunol.0804263

Modeling the ternary complex TCR-Vβ/collagenii(261-273)/HLA-DR4 associated with rheumatoid arthritis 10.1371/journal.pone.0011550

Administration of PLP139-151 primes T cells distinct from those spontaneously responsive in vitro to this antigen. 10.4049/jimmunol.180.10.6611

Collagen-specific T-cell repertoire in blood and synovial fluid varies with disease activity in early rheumatoid arthritis 10.1186/ar2553

Mycobacterium tuberculosis in the adjuvant modulates the balance of Th immune response to self-antigen of the CNS without influencing a "core" repertoire of specific T cells. 10.1093/intimm/dxh376

Collagen-specific TCR Repertoire usage in RA and cytokine secretion. 10.3389/conf.fimmu.2013.02.00724

Immunomodulation by Gut Microbiota: Role of Toll-Like Receptor Expressed by T Cells 10.1155/2014/586939

MBP 85-99-SPECIFIC TCR REPERTOIRE IN DRB1*15 PATIENTS AFFECTED BY MULTIPLE SCLEROSIS 10.3389/conf.fimmu.2013.02.01025

A single non-synonymous polymorphism of TLR2 is sufficient to recapitulate the variability of Experimental Multiple Sclerosis 10.3389/conf.fimmu.2013.02.00963

Specific oligoclonal T-cell recruitment within epicardial adipose tissue of patients with acute coronary syndrome: evidence for a local, immune-mediated, pathogenetic mechanism 10.3389/conf.fimmu.2013.02.00726

Impact of infectious agents on trafficking of effector T cells is mediated by a polymorphic site of TLR2 and CD44 isoforms expression. 10.3389/conf.fimmu.2013.02.00725

Collagen Specific T-Cell Repertoire and HLA-DR Alleles: Biomarkers of Active Refractory Rheumatoid Arthritis 10.1016/j.ebiom.2015.11.019

The pathway toll like receptor 2 — CD44: A pathogenetic mechanism and therapeutic target for inflammation in autoimmune disease 10.1016/j.jneuroim.2014.08.152

PE-PGRS33 contributes to Mycobacterium tuberculosis entry in macrophages through interaction with TLR2 10.1371/journal.pone.0150800

Toll-like receptor 2 mediates in vivo pro- and anti-inflammatory effects of Mycobacterium Tuberculosis and modulates autoimmune encephalomyelitis 10.3389/fimmu.2016.00191

Multiple Sclerosis Drug Therapy: From the Classical Pharmaceutical Down to Cellular and Molecular Approach 10.2174/9781681082950116040003

Is Citrullination Required for the Presence of Restricted Clonotypes Reacting With Type II Collagen? Comment on the Article by Chemin et al 10.1002/art.39661

Low reliability of anti-KIR4.183-120 peptide auto-antibodies in multiple sclerosis patients. 10.1177/1352458517711275

Synovial features of patients with rheumatoid arthritis and psoriatic arthritis in clinical and ultrasound remission differ under anti-TNF therapy: a clue to interpret different chances of relapse after clinical remission? 10.1136/annrheumdis-2016-210424

Porphyromonas gingivalis and the pathogenesis of rheumatoid arthritis: Analysis of various compartments including the synovial tissue 10.1186/ar4243

MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis 10.1038/ncomms15877

Prevalence and Determinants of Peripheral Microvascular Endothelial Dysfunction in Rheumatoid Arthritis Patients: A Multicenter Cross-Sectional Study 10.1155/2018/6548715

The S100B Inhibitor Pentamidine Ameliorates Clinical Score and Neuropathology of Relapsing-Remitting Multiple Sclerosis Mouse Model 10.3390/cells9030748

Selective Inhibitors of T Cell Receptor Recognition of Antigen-MHC Complexes for Rheumatoid Arthritis 10.1021/acsmedchemlett.8b00601

Complex Muco-cutaneous Manifestations of CARMIL2-associated Combined Immunodeficiency: A Novel Presentation of Dysfunctional Epithelial Barriers 10.2340/00015555-3370

Synovial predictors of differentiation to definite arthritis in patients with seronegative undifferentiated peripheral inflammatory arthritis: MicroRNA signature, histological, and ultrasound features 10.3389/fmed.2018.00186

Cytokine Profile in an Adolescent With Pediatric Multisystem Inflammatory Syndrome Temporally Related to COVID-19 10.1097/inf.0000000000002802

Past and Future of the Molecular Characterization of the T Cell Repertoire: Some Highlights of Eli Sercarz' Contributions 10.1615/critrevimmunol.2020034613

Growing role of S100B protein as a putative therapeutic target for neurological- and nonneurological-disorders 10.1016/j.neubiorev.2021.04.035

Modeling rejection immunity 10.1186/1742-4682-9-18

Distinct and non-overlapping T cell receptor repertoires expanded by DNA vaccination in wild-type and HER-2 transgenic BALB/c mice 10.4049/jimmunol.177.11.7626

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Impact of pe_pgrs33 gene polymorphisms on mycobacterium tuberculosis infection and pathogenesis 10.3389/fcimb.2017.00137

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Selection of Similar Naive T Cell Repertoires but Induction of Distinct T Cell Responses by Native and Modified Antigen 10.4049/jimmunol.172.6.3447

Control of cellular and humoral immune responses by peptides containing T-cell epitopes 10.1101/sqb.1989.054.01.059

Immunological activity of covalently linked T-cell epitopes 10.1038/343381a0

Targeting IL-12, the key cytokine driving Th1-mediated autoimmune diseases 10.1159/000058691

Antitumor immunization of mothers delays tumor development in cancer-prone offspring 10.1080/2162402X.2015.1005500

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Alternative splicing of neurexins 1–3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis 10.1016/j.expneurol.2020.113497

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Failure of presented, non-dominant self epitope to induce tolerance: Implications for autoimmune diseases 10.3109/08820139409066828

Size-exclusion high-performance liquid chromatography of immune complexes isolated for patients with acute leukaemia. Preliminary observations 10.1016/0378-4347(87)80431-0

Serum S100B protein as a marker of severity in Covid-19 patients 10.1038/s41598-020-75618-0

Cord blood mononuclear cell responsiveness to beta-lactoglobulin: T-cell activity in ‘atopy-prone’ and ‘non-atopy-prone’ newborns 10.1159/000236692

A plasmid family containing two different expression cassettes suitable for immunomodulation and genetic immunization 10.1006/plas.1998.1339

The mode of protein antigen administration determines preferential presentation of peptide-class II complexes by lymph node dendritic or B cells 10.1093/intimm/9.1.9

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Preparation of a monoclonal antibody against rat MnSOD, using a COOH-terminal peptide 10.1006/bbrc.1993.2101

Normal B cells fail to secrete interleukin-12 10.1002/eji.1830270707

TLR2: A crossroads between infections and autoimmunity? 10.1177/039463201102400301

House dust mite allergy in Italy—Diagnostic and clinical relevance of Der p 23 (and of minor allergens): A real-life, multicenter study 10.1111/all.13776

Molecular characterization of the T cell repertoire using immunoscope analysis and its possible implementation in clinical practice 10.2174/1566524013363690

Suppression of established experimental autoimmune encephalomyelitis and formation of meningeal lymphoid follicles by lymphotoxin β receptor-Ig fusion protein 10.1016/j.jneuroim.2006.06.015

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CD8α⁺ dendritic cells prime TCR-peptide-reactive regulatory CD4⁺FOXP3^- T cells 10.1002/eji.200939608

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Chromatographic and electrophoretic studies of immune complexes in non-A, non-B hepatitis 10.1016/S0378-4347(00)81926-X

Human IgG Antinuclear Antibodies Induce Pregnancy Loss in Mice by Increasing Immune Complex Deposition in Placental Tissue: In Vivo Study 10.1111/aji.12429

Immune response at birth, long-term immune memory and 2 years follow-up after in-utero anti-HBV DNA immunization 10.1038/sj.gt.3302179

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Antinuclear Autoantibodies in Women with Recurrent Pregnancy Loss 10.1111/j.1600-0897.2010.00863.x

Synthetic PreImplantation Factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response 10.1371/journal.pone.0180642

Simultaneous onset of mycobacterium kansasii pulmonary infection and systemic lupus erythematosus: A case report 10.12659/AJCR.929866

The level of manganese superoxide dismutase content is an independent prognostic factor for glioblastoma. Biological mechanisms and clinical implications 10.1054/bjoc.2000.1594

The level of MnSOD is directly correlated with grade of brain tumours of neuroepithelial origin 10.1038/bjc.1996.648

Evidence of lung perfusion defects and ongoing inflammation in an adolescent with post-acute sequelae of SARS-CoV-2 infection 10.1016/s2352-4642(21)00196-6

Haemophilus parasuis (Glaesserella parasuis) as a Potential Driver of Molecular Mimicry and Inflammation in Rheumatoid Arthritis 10.3389/fmed.2021.671018

Nathalie deboosere

deboosere Nathalie

ORCID: 0000-0002-2873-5485

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton. 10.15252/embr.201744371

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling. 10.1016/j.celrep.2017.08.101

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone. 10.3390/toxins9070227

Phenotypic assays for Mycobacterium tuberculosis infection. 10.1002/cyto.a.23129

Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. 10.1021/acschembio.7b00091

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection. 10.1038/srep29297

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis. 10.1111/cmi.12619

A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening. 10.3791/51114

Adhesion of human pathogenic enteric viruses and surrogate viruses to inert and vegetal food surfaces. 10.1016/j.fm.2012.04.007

Viral elution and concentration method for detection of influenza A viruses in mud by real-time RT-PCR. 10.1016/j.jviromet.2011.10.013

Comparison of chlorine and peroxyacetic-based disinfectant to inactivate Feline calicivirus, Murine norovirus and Hepatitis A virus on lettuce. 10.1016/j.ijfoodmicro.2011.08.011

Direct detection of highly pathogenic avian influenza A/H5N1 virus from mud specimens. 10.1016/j.jviromet.2011.06.002

Development and validation of a concentration method for the detection of influenza a viruses from large volumes of surface water. 10.1128/aem.02484-10

A predictive microbiology approach for thermal inactivation of Hepatitis A virus in acidified berries. 10.1016/j.fm.2010.05.018

Assessment of the removal and inactivation of influenza viruses H5N1 and H1N1 by drinking water treatment. 10.1016/j.watres.2010.01.013

Intra-laboratory validation of a concentration method adapted for the enumeration of infectious F-specific RNA coliphage, enterovirus, and hepatitis A virus from inoculated leaves of salad vegetables. 10.1016/j.ijfoodmicro.2005.11.007

Modelling effect of physical and chemical parameters on heat inactivation kinetics of hepatitis A virus in a fruit model system. 10.1016/j.ijfoodmicro.2003.10.015

Host-pathogen systems for early drug discovery against tuberculosis. 10.1016/j.mib.2017.11.017

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids. 10.1073/pnas.1707840114

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis. 10.1038/s41598-017-11843-4

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages. 10.1016/j.chom.2017.07.020

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles. 10.1038/s41598-017-05453-3

Host-directed therapies offer novel opportunities for the fight against tuberculosis. 10.1016/j.drudis.2017.05.005

Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs. 10.1016/j.ijpharm.2017.05.030

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis. 10.3389/fcimb.2017.00137

Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections. 10.2217/nnm-2016-0364

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420. 10.1126/science.aag1006

How can nanoparticles contribute to antituberculosis therapy? 10.1016/j.drudis.2017.01.011

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism. 10.1007/s00401-016-1652-z

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria. 10.1111/mmi.13535

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization. 10.1016/j.str.2016.07.009

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro. 10.1007/s00705-016-2771-5

[Mycolactone: the amazing analgesic mycobacterial toxin]. 10.1051/medsci/20163202007

A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters. 10.1039/c5ob02630j

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action. 10.1128/jvi.01473-15

Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro. 10.3389/fmicb.2015.00488

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system. 10.1016/j.vaccine.2015.03.083

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo. 10.1371/journal.ppat.1004650

[High content screening in chemical biology: overview and main challenges]. 10.1051/medsci/20153102016

Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays. 10.1007/978-1-4939-2450-9_24

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1. 10.1021/cb5007163

High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis. 10.1128/aac.03705-14

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways. 10.1016/j.cell.2014.04.040

Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches. 10.1021/jm500422b

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. 10.1038/nm.3262

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence. 10.1371/journal.pone.0047573

Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. 10.1021/jm300377g

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors. 10.1021/jm200825u

A novel specific edge effect correction method for RNA interference screenings. 10.1093/bioinformatics/btr648

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis. 10.1371/journal.pone.0026675

High-content screening in infectious diseases. 10.1016/j.cbpa.2011.05.023

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors. 10.1021/jm200076a

Shortening the drug discovery pipeline: small molecule high content screening for lead discovery in neglected disease. 10.1186/1753-6561-5-s1-p38

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling. 10.1371/journal.ppat.1001100

High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery. 10.4155/fmc.10.223

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ. 10.1099/mic.0.038133-0

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors. 10.1371/journal.ppat.1000645

Systematic genetic nomenclature for type VII secretion systems. 10.1371/journal.ppat.1000507

Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting. 10.1016/j.biomaterials.2009.09.044

Automated HTS/HCS for antivirals using visual HIV full replication assays. 10.1186/1742-4690-6-s2-p82

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis. 10.1126/science.1171583

Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure. 10.1177/1087057108328762

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP. 10.1371/journal.ppat.0040033

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity. 10.1128/jb.00469-07

[Aquatic insects and transmission of Mycobacterium ulcerans]. 10.1051/medsci/20072367572

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis. 10.1371/journal.ppat.0030062

Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva. 10.1371/journal.pmed.0040064

Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues. 10.1016/j.bmc.2006.12.009

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence. 10.1128/jb.00631-06

High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection. 10.1128/iai.02086-05

Benzofuro[3,2-f][1]benzopyrans: a new class of antitubercular agents. 10.1016/j.bmc.2006.03.033

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis. 10.1128/iai.74.4.2128-2137.2006

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. 10.1128/iai.74.1.88-98.2006

Tuberculosis: from genome to vaccine. 10.1586/14760584.4.4.541

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics. 10.1099/mic.0.27799-0

Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system. 10.4049/jimmunol.174.6.3570

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis. 10.1016/j.tube.2004.09.009

ESAT-6 proteins: protective antigens and virulence factors? 10.1016/j.tim.2004.09.007

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens. 10.1086/421468

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6. 10.1128/iai.72.4.2170-2176.2004

CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family. 10.1128/iai.71.12.7173-7177.2003

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. 10.1038/nm859

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. 10.1046/j.1365-2958.2002.03237.x

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant. 10.1128/iai.70.10.5568-5578.2002

Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides. 10.1021/bi015732y

IRG1 controls immunometabolic host response and restricts intracellular Mycobacterium tuberculosis infection 10.1101/761551

Large scale screening discovers clofoctol as an inhibitor of SARS-CoV-2 replication that reduces COVID-19-like pathology 10.1101/2021.06.30.450483

Stefano ROCCA

ROCCA Stefano

ORCID: 0000-0001-8897-5707

First molecular characterization of canine parvovirus strains in Sardinia, Italy 10.1007/s00705-017-3457-3

Sequence, cloning, expression and characterisation of the 81-kDa surface membrane protein (P80) of Mycoplasma agalactiae 10.1016/S0378-1097(01)00234-8

Impact of pe_pgrs33 gene polymorphisms on mycobacterium tuberculosis infection and pathogenesis 10.3389/fcimb.2017.00137

Interferon Regulatory Factor 8-Deficiency Determines Massive Neutrophil Recruitment but T Cell Defect in Fast Growing Granulomas during Tuberculosis 10.1371/journal.pone.0062751

Molecular investigation and phylogeny of anaplasma spp. in mediterranean ruminants reveal the presence of neutrophil-tropic strains closely related to A. platys 10.1128/AEM.03129-13

Detection of Mycobacterium avium spp. paratuberculosis (Map) in samples of sheep paratuberculosis (Johne's disease or JD) and human Crohn's disease (CD) using liquid phase RT-PCR, in situ RT-PCR and immunohistochemistry 10.1016/j.smallrumres.2009.12.020

A physical map of the Mycoplasma agalactiae strain PG2 genome 10.1016/S0378-1135(00)00389-8

Evaluation of the anti-tuberculosis activity generated by different multigene DNA vaccine constructs 10.1016/j.micinf.2008.02.012

Paratuberculosis in sheep: Histochemical, immunohistochemical and in situ hybridization evidence of in utero and milk transmission 10.1016/j.rvsc.2016.04.006

REAC regenerative treatment efficacy in experimental chondral lesions: A pilot study on ovine animal model 10.2147/CIA.S140976

Antigenic profiles of recombinant proteins from Mycobacterium avium subsp. paratuberculosis in sheep with Johne's disease 10.1016/j.vetimm.2007.10.020

Presence of Jaagsiekte sheep retrovirus in tissue sections from human bronchioloalveolar carcinoma depends on patients' geographical origin 10.1016/j.humpath.2007.10.008

Application of 2-D DIGE to formalin-fixed, paraffin-embedded tissues 10.1002/pmic.201000353

Proteomic changes in the ileum of sheep infected with Mycobacterium avium subspecies paratuberculosis 10.1016/j.tvjl.2016.11.012

Neutrophil extracellular traps in sheep mastitis 10.1186/s13567-015-0196-x

Experimental vaccination against Mycoplasma agalactiae using different inactivated vaccines 10.1016/S0264-410X(99)00070-5

The hbhA gene of Mycobacterium tuberculosis is specifically upregulated in the lungs but not in the spleens of aerogenically infected mice 10.1128/IAI.74.5.3006-3011.2006

Mycobacterium chelonae associated with tumor-like skin and oral masses in farmed Russian sturgeons (Acipenser gueldenstaedtii) 10.1186/1746-6148-10-18

Treatment with embryonic stem-like cells into osteochondral defects in sheep femoral condyles 10.1186/s12917-014-0301-9

Homologous prime boosting based on intranasal delivery of non-pathogenic invasive Escherichia coli expressing MPT64, decreases Mycobacterium tuberculosis dissemination 10.1016/j.vaccine.2014.05.060

Exocyclic DNA adducts in sheep with skeletal fluorosis resident in the proximity of the Portoscuso-Portovesme industrial estate on Sardinia Island, Italy 10.1039/c5tx00045a

Exploiting immunotheraphy in Mycobacterium tuberculosis-infected mice: Sphingosine 1-phosphate treatment results in a protective or detrimental effect depending on the stage of infection 10.1177/039463200902200120

Comparison of restriction pattern polymorphism of mycoplasma agalactiae and mycoplasma bovis by pulsed field gel electrophoresis 10.1046/j.1439-0450.1999.00226.x

Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer 10.1186/s12977-017-0329-6

Liver Injury, Endotoxemia, and Their Relationship to Intestinal Microbiota Composition in Alcohol-Preferring Rats 10.1111/acer.13900

Characterization of paucibacillary ileal lesions in sheep with subclinical active infection by Mycobacterium avium subsp. Paratuberculosis 10.1186/s13567-018-0612-0

Mycoplasma lipoproteins are major determinants of neutrophil extracellular trap formation 10.1111/cmi.12613

The use of embryonic cells in the treatment of osteochondral defects of the knee: An ovine in vivo study 10.11138/jts/2016.4.2.070

PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis 10.1111/j.1462-5822.2011.01721.x

Surface expression of MPT64 as a fusion with the PE domain of PE-PGRS33 enhances Mycobacterium bovis BCG protective activity against Mycobacterium tuberculosis in mice 10.1128/IAI.00267-10

Sheep embryonic stem-like cells engrafted into sheep femoral condyle osteochondral defects: 4-year follow-up 10.1186/s12917-018-1532-y

Lysophosphatidic acid enhances antimycobacterial response during in vivo primary Mycobacterium tuberculosis infection 10.1016/j.cellimm.2011.05.014

Cloning and expression of two fragments of the S gene of canine coronavirus type I 10.1016/j.jviromet.2003.12.003

2-D PAGE and MS analysis of proteins from formalin-fixed, paraffin-embedded tissues 10.1002/pmic.200900010

Map lesions: In situ investigation on samples of multibacillar and paucibacillar ovine PTBC 10.1007/s11259-006-0057-1

Application of 2D-DIGE to formalin-fixed diseased tissue samples from hospital repositories: Results from four case studies 10.1002/prca.201200054

Sheep embryonic stem-like cells transplanted in full-thickness cartilage defects 10.1002/term.151

Cathelicidin production and release by mammary epithelial cells during infectious mastitis 10.1016/j.vetimm.2017.06.002

Production and release of antimicrobial and immune defense proteins by mammary epithelial cells following Streptococcus uberis infection of sheep 10.1128/IAI.00291-13

Impact of fixation time on GeLC-MS/MS proteomic profiling of formalin-fixed, paraffin-embedded tissues 10.1016/j.jprot.2011.03.015

Ovis aries Papillomavirus 3 in Ovine Cutaneous Squamous Cell Carcinoma 10.1177/0300985817705171

ivana palucci

palucci ivana

ORCID: 0000-0003-2106-1761

Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection 10.1111/joim.12714

Clinical isolates of the modern Mycobacterium tuberculosis lineage 4 evade host defense in human macrophages through eluding IL-1β-induced autophagy 10.1038/s41419-018-0640-8

IP-10 contributes to the inhibition of mycobacterial growth in an ex vivo whole blood assay 10.1016/j.ijmm.2019.05.005

Combined use of Quantiferon and HBHA-based IGRA supports tuberculosis diagnosis and therapy management in children 10.1016/j.jinf.2018.09.011

Monosodium urate crystals promote innate anti-mycobacterial immunity and improve BCG efficacy as a vaccine against tuberculosis 10.1371/journal.pone.0127279

Sonic hedgehog is expressed in human brain arteriovenous malformations and induces arteriovenous malformations in vivo 10.1177/0271678X20912405

A rapid diagnostic workflow for cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae detection from blood cultures by MALDI-TOF mass spectrometry 10.1371/journal.pone.0185935

Impact of pe_pgrs33 gene polymorphisms on mycobacterium tuberculosis infection and pathogenesis 10.3389/fcimb.2017.00137

PE-PGRS33 contributes to Mycobacterium tuberculosis entry in macrophages through interaction with TLR2 10.1371/journal.pone.0150800

First description of agonist and antagonist IP-10 in urine of patients with active TB 10.1016/j.ijid.2018.09.001

Interferon Regulatory Factor 8-Deficiency Determines Massive Neutrophil Recruitment but T Cell Defect in Fast Growing Granulomas during Tuberculosis 10.1371/journal.pone.0062751

PPE-MPTR genes are differentially expressed by Mycobacterium tuberculosis in vivo 10.1016/j.tube.2011.08.002

Evaluation of the new NucliSENS EasyQ KPC test for rapid detection of Klebsiella pneumoniae carbapenemase genes (blaKPC) 10.1128/JCM.00284-12

PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis 10.1111/j.1462-5822.2011.01721.x

Impact of protein domains on PE-PGRS30 polar localization in Mycobacteria 10.1371/journal.pone.0112482

Host Directed Therapies for Tuberculosis: Futures Strategies for an Ancient Disease 10.1159/000490478

Inhibition of Transglutaminase 2 as a Potential Host-Directed Therapy Against Mycobacterium tuberculosis 10.3389/fimmu.2019.03042

Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 10.1002/cmdc.201700759

Catheter-related bacteremia by Cupriavidus metallidurans 10.1016/j.diagmicrobio.2014.09.015

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 of Mycobacterium tuberculosis 10.1111/2049-632X.12096

First bloodstream infection caused by Prevotella copri in a heart failure elderly patient with Prevotella-dominated gut microbiota: A case report 10.1186/s13099-019-0325-6

Incidental intraoperative diagnosis of Mycobacterium abscessus meningeal infection: a case report and review of the literature 10.1007/s15010-018-1141-5

SARS-CoV-2 Antigen Detection to Expand Testing Capacity for COVID-19: Results from a Hospital Emergency Department Testing Site 10.3390/diagnostics11071211

Flavio De Maio

De Maio Flavio

ORCID: 0000-0002-4744-9820

Graphene Oxide-Linezolid Combination as Potential New Anti-Tuberculosis Treatment 10.3390/nano10081431

PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host–pathogen interaction 10.1080/21505594.2020.1785815

PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response 10.3390/cells10010161

First description of the katG gene deletion in a Mycobacterium tuberculosis clinical isolate and its impact on the mycobacterial fitness 10.1016/j.ijmm.2021.151506

Direct use of eazyplex® superbug CRE assay from positive blood cultures in conjunction with inpatient infectious disease consulting for timely appropriate antimicrobial therapy in escherichia coli and klebsiella pneumoniae bloodstream infections 10.2147/IDR.S206323

Combined use of Quantiferon and HBHA-based IGRA supports tuberculosis diagnosis and therapy management in children 10.1016/j.jinf.2018.09.011

Comparison of Mycoplasma IES, Mycofast Revolution and Mycoplasma IST2 to detect genital mycoplasmas in clinical samples 10.3855/jidc.8039

Profiling the Gastrointestinal Microbiota 10.1007/978-1-0716-1302-3_10

Impact of pe_pgrs33 gene polymorphisms on mycobacterium tuberculosis infection and pathogenesis 10.3389/fcimb.2017.00137

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells 10.1080/21505594.2021.1897247

Enhanced chemotherapy for glioblastoma multiforme mediated by functionalized graphene quantum dots 10.3390/ma13184139

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in children with household exposure to adults with COVID-19: Preliminary findings 10.1002/ppul.25280

Rapid and safe one-step extraction method for the identification of Brucella strains at genus and species level by MALDI-TOF mass spectrometry 10.1371/journal.pone.0197864

Optimized Use of the MALDI BioTyper System and the FilmArray BCID Panel for Direct Identification of Microbial Pathogens from Positive Blood Cultures 10.1128/JCM.02590-15

Graphene oxide prevents mycobacteria entry into macrophages through extracellular entrapment 10.1039/c8na00413g

Impact of protein domains on PE-PGRS30 polar localization in Mycobacteria 10.1371/journal.pone.0112482

Understanding cutaneous tuberculosis: Two clinical cases 10.1099/jmmcr.0.005070

Face masks and nanotechnology: Keep the blue side up 10.1016/j.nantod.2021.101077

Nasopharyngeal Microbiota Profiling of SARS-CoV-2 Infected Patients 10.1186/s12575-020-00131-7

First case of bacteremic liver abscess caused by an ST260-related (ST1861), hypervirulent Klebsiella pneumoniae 10.1016/j.jinf.2016.04.006

Accuracy of QuantiFERON-TB gold plus test for diagnosis of mycobacterium tuberculosis infection in children 10.1128/JCM.00272-20

First bloodstream infection caused by Prevotella copri in a heart failure elderly patient with Prevotella-dominated gut microbiota: A case report 10.1186/s13099-019-0325-6

IP-10 contributes to the inhibition of mycobacterial growth in an ex vivo whole blood assay 10.1016/j.ijmm.2019.05.005

Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins 10.1016/j.csbj.2021.03.014

Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis 10.1016/j.micinf.2020.08.006

Immunoinformatic analysis of the SARS-CoV-2 envelope protein as a strategy to assess cross-protection against COVID-19 10.1016/j.micinf.2020.05.013

PE-PGRS33 contributes to Mycobacterium tuberculosis entry in macrophages through interaction with TLR2 10.1371/journal.pone.0150800

Monitoring COVID-19 Transmission Risks by Quantitative RealTime PCR Tracing of Droplets in Hospital and Living Environments 10.1128/MSPHERE.01070-20

Re-evaluating positive serum samples for SARS-CoV-2-specific IgA and IgG antibodies using an in-house serological assay 10.1016/j.cmi.2020.12.014

Graphene oxide coatings prevent Candida albicans biofilm formation with a controlled release of curcumin-loaded nanocomposites 10.2217/nnm-2018-0183

Comparative evaluation of BD phoenix and Vitek 2 systems for species identification of common and uncommon pathogenic yeasts 10.1128/JCM.01581-13

Carbon nanomaterials: a new way against tuberculosis 10.1080/17434440.2019.1671820

Simplified testing method for direct detection of carbapenemase-producing organisms from positive blood cultures using the NG-Test CARBA 5 assay 10.1128/AAC.00550-19

Vacuum-assisted closure (VAC®) systems and microbiological isolation of infected wounds 10.1186/s13017-018-0216-z

Evaluation of PE PGRS33 as a potential surface target for humoral responses against Mycobacterium tuberculosis 10.1093/femspd/ftx100

Inhibition of Transglutaminase 2 as a Potential Host-Directed Therapy Against Mycobacterium tuberculosis 10.3389/fimmu.2019.03042

Antifungal susceptibility profiles of bloodstream yeast isolates by sensititre yeastone over nine years at a large Italian teaching hospital 10.1128/AAC.00285-15

Lack of Response to HBHA in HIV-Infected Patients with Latent Tuberculosis Infection 10.1111/sji.12493

Relevance of QuantiFERON-TB Gold Plus and Heparin-Binding Hemagglutinin Interferon-γ Release Assays for Monitoring of Pulmonary Tuberculosis Clearance: A Multicentered Study 10.3389/fimmu.2020.616450

The mycobacterial HBHA protein: A promising biomarker for tuberculosis 10.2174/0929867325666181029165805

Graphene nanoplatelet and graphene oxide functionalization of face mask materials inhibits infectivity of trapped SARS-CoV-2 10.1016/j.isci.2021.102788

Multi-country evaluation of RISK6, a 6-gene blood transcriptomic signature, for tuberculosis diagnosis and treatment monitoring 10.1038/s41598-021-93059-1

Staphylococcus aureus ventilator-associated pneumonia in patients with COVID-19: clinical features and potential inference with lung dysbiosis 10.1186/s13054-021-03623-4

COVID-19 influences lung microbiota dynamics and favors the emergence of rare infectious diseases: A case report of Hafnia Alvei pneumonia. 10.1016/j.jcrc.2021.04.008

Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples 10.1016/j.cmi.2021.03.029