Dominant drivers of the human plasma metabolome
Jingyuan Fu
Lianmin Chen
Sergio Andreu-Sánchez
Daoming Wang
Hannah E. Augustijn
Daria Zhernakova
Alexander Kurilshikov
Arnau Vich Vila
Rinse Weersma
Marnix Medema
Mihai Netea
Folkert Kuipers
Cisca Wijmenga
Alexandra Zhernakova
Jingyuan Fu
Fu Jingyuan
ORCID: 0000-0001-5578-1236
The non-coding genome in cancer
10.21037/ncri.2017.12.03
Apple or Pear: Size and Shape Matter
10.1016/j.cmet.2015.03.016
Multi-ethnic studies in complex traits
10.1093/hmg/ddr386
MetaNetwork: a computational protocol for the genetic study of metabolic networks
10.1038/nprot.2007.96
Pharmacomicrobiomics: a novel route towards personalized medicine?
10.1007/s13238-018-0547-2
A system biology perspective on environment–host–microbe interactions
10.1093/hmg/ddy137
Gut microbiome and lipid metabolism
10.1097/mol.0000000000000308
Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity
10.1016/j.cell.2016.11.046
Host Genetics and Gut Microbiome: Challenges and Perspectives
10.1016/j.it.2017.06.003
Proton pump inhibitors affect the gut microbiome
10.1136/gutjnl-2015-310376
The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood LipidsNovelty and Significance
10.1161/circresaha.115.306807
GWAS as a Driver of Gene Discovery in Cardiometabolic Diseases
10.1016/j.tem.2015.10.004
Optimal Design and Analysis of Genetic Studies on Gene Expression
10.1534/genetics.105.047001
Defining gene and QTL networks
10.1016/j.pbi.2009.01.003
The immunity–diet–microbiota axis in the development of metabolic syndrome
10.1097/mol.0000000000000154
Genetics of coronary artery disease: Genome-wide association studies and beyond
10.1016/j.atherosclerosis.2012.05.015
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
10.1126/science.aad3369
Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets.
10.1161/jaha.117.008105
Environment dominates over host genetics in shaping human gut microbiota
10.1038/nature25973
A liver-specific long noncoding RNA with a role in cell viability is elevated in human nonalcoholic steatohepatitis
10.1002/hep.29034
The influence of proton pump inhibitors and other commonly used medication on the gut microbiota
10.1080/19490976.2017.1284732
Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity
10.1016/j.cell.2016.10.020
Inter-tissue gene co-expression networks between metabolically healthy and unhealthy obese individuals
10.1371/journal.pone.0167519
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease
10.1136/gutjnl-2016-312135
The effect of host genetics on the gut microbiome
10.1038/ng.3663
Understanding human immune function using the resources from the Human Functional Genomics Project
10.1038/nm.4140
A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency
10.1136/gutjnl-2016-312398
Are hypertriglyceridemia and low HDL causal factors in the development of insulin resistance?
10.1016/j.atherosclerosis.2013.12.013
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.
10.1186/s40168-018-0479-3
Detection of stable community structures within gut microbiota co-occurrence networks from different human populations
10.7717/peerj.4303
Population-level analysis of gut microbiome variation
10.1126/science.aad3503
Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells
10.1002/hep.27985
Cell Specific eQTL Analysis without Sorting Cells
10.1371/journal.pgen.1005223
Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels
10.1186/s13073-015-0152-4
Genetic and epigenetic regulation of gene expression in fetal and adult human livers
10.1186/1471-2164-15-860
Extraintestinal manifestations and complications in inflammatory bowel disease: from shared genetics to shared biological pathways.
10.1097/mib.0000000000000032
The genome revolution and its role in understanding complex diseases
10.1016/j.bbadis.2014.05.002
Systems genetics: From GWAS to disease pathways
10.1016/j.bbadis.2014.04.025
Correlation of genetic risk and messenger RNA expression in a Th17/IL23 pathway analysis in inflammatory bowel disease.
10.1097/mib.0000000000000013
Pleiotropic effects of lipid genes on plasma glucose, hba1c, and homa-ir levels
10.2337/db13-1800
Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression
10.1371/journal.pgen.1003201
Limited Evidence for Parent-of-Origin Effects in Inflammatory Bowel Disease Associated Loci
10.1371/journal.pone.0045287
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
10.1371/journal.pgen.1002431
Trans-eqtls reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the hla
10.1371/journal.pgen.1002197
Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
10.1002/hep.24307
Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: Meta-analysis of three genome-wide association studies
10.1371/journal.pone.0006138
DesignGG: An R-package and web tool for the optimal design of genetical genomics experiments
10.1186/1471-2105-10-188
Analysis of HLA and Non-HLA Alleles Can Identify Individuals at High Risk for Celiac Disease
10.1053/j.gastro.2009.05.040
System-wide molecular evidence for phenotypic buffering in Arabidopsis
10.1038/ng.308
Genetical genomics: Spotlight on QTL hotspots
10.1371/journal.pgen.1000232
Optimal design of genetic studies of gene expression with two-color microarrays in outbred crosses
10.1534/genetics.108.090308
Integrative analyses of genetic variation in enzyme activities of primary carbohydrate metabolism reveal distinct modes of regulation in Arabidopsis thaliana
10.1186/gb-2008-9-8-r129
Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci
10.1073/pnas.0610429104
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans
10.1371/journal.pgen.0020222
The genetics of plant metabolism
10.1038/ng1815
Combining microarrays and genetic analysis
10.1093/bib/6.2.135
Author Correction: Gut microbiome structure and metabolic activity in inflammatory bowel disease.
10.1038/s41564-019-0442-5
Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk: A Cross-Sectional Study.
10.1161/circresaha.118.314642
Anti-inflammatory Gut Microbial Pathways Are Decreased During Crohn's Disease Exacerbations.
10.1093/ecco-jcc/jjz077
Structural variation in the gut microbiome associates with host health
10.1038/s41586-019-1065-y
Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome
10.472/eaap8914
Role of gut microbiota in chronic low-grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies
10.1111/obr.12750
Is gut microbiota a relevant and competitive dietary target for cardio-metabolic health? Proceedings of an expert workshop
10.1016/j.tifs.2018.09.005
Shared gut, but distinct oral microbiota composition in primary Sjögren's syndrome and systemic lupus erythematosus
10.1016/j.jaut.2018.10.009
Erratum to: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome (Nature Genetics, (2018), 50, 11, (1524-1532), 10.1038/s41588-018-0224-7)
10.1038/s41588-018-0275-9
Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome
10.1038/s41588-018-0224-7
A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis
10.1161/CIRCRESAHA.118.313234
Gut microbiome structure and metabolic activity in inflammatory bowel disease
10.1038/s41564-018-0306-4
Gut microbiota composition associated with stool consistency
10.1136/gutjnl-2015-310328
SLC39A8 missense variant is associated with Crohn’s disease but does not have a major impact on gut microbiome composition in healthy subjects
10.1371/journal.pone.0211328
Analysis of 1135 gut metagenomes identifies sex-specific resistome profiles
10.1080/19490976.2018.1528822
Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity
10.1038/nutd.2014.43
Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease
10.1093/hmg/ddq264
Megasphaera elsdeniiLactate degradation pattern shifts in rumen acidosis models
10.3389/fmicb.2019.00162
Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases
10.1038/s41588-019-0350-x
Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
10.1212/WNL.0000000000007313
Dysbiosis of the buccal mucosa microbiome in primary Sjögren’s syndrome patients
10.1093/rheumatology/key215
Systems genetics approach reveals cross-talk between bile acids and intestinal microbes
10.1371/journal.pgen.1008307
Intestinal microbiome composition and its relation to joint pain and inflammation
10.1038/s41467-019-12873-4
The role of the gut microbiome in graft fibrosis after pediatric liver transplantation
10.1007/s00439-020-02221-8
A systematic analysis of metabolic pathways in the human gut microbiota
10.1101/2021.02.25.432841
Oral Microbiome in Relation to Periodontitis Severity and Systemic Inflammation
10.3390/ijms22115876
Discovery, diversity and functional associations of crAss-like phages in human gut metagenomes from four Dutch cohorts
10.1101/2021.06.01.446427
Dominant drivers of the human plasma metabolome
10.21203/rs.3.rs-688716/v1
Long Non-Coding RNAs Involved in Progression of Non-Alcoholic Fatty Liver Disease to Steatohepatitis
10.3390/cells10081883
Daoming Wang
Wang Daoming
ORCID: 0000-0003-4623-8527
HLA-A*24:388N : a novel HLA-A*24 allele identified by sequence-based typing
10.1111/tan.13149
Alterations in the human gut microbiome associated with Helicobacter pylori infection
10.1002/2211-5463.12694
Gut Microbiota Changes and Their Relationship with Inflammation in Patients with Acute and Chronic Insomnia
10.2147/NSS.S271927
Gut microbial structural variations as determinants of human bile acid metabolism
10.1101/2021.02.28.432952
The long-term genetic stability and individual specificity of the human gut microbiome
10.1016/j.cell.2021.03.024
Discovery, diversity and functional associations of crAss-like phages in human gut metagenomes from four Dutch cohorts
10.1101/2021.06.01.446427
Dominant drivers of the human plasma metabolome
10.21203/rs.3.rs-688716/v1
Marnix H. Medema
Medema Marnix H.
ORCID: 0000-0002-2191-2821
antiSMASH
10.1007/978-1-4899-7478-5_703
Bioinformatics Approaches and Software for Detection of Secondary Metabolic Gene Clusters
10.1007/978-1-62703-122-6_2
Synthetic Biology in Streptomyces Bacteria
10.1016/b978-0-12-385075-1.00021-4
Computational approaches to natural product discovery
10.1038/nchembio.1884
Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms
10.1038/nrmicro2478
A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis
10.1371/journal.pcbi.1004016
Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism
10.1016/j.febslet.2011.06.014
MultiMetEval: Comparative and Multi-Objective Analysis of Genome-Scale Metabolic Models
10.1371/journal.pone.0051511
The future of industrial antibiotic production: From random mutagenesis to synthetic biology
10.4161/bbug.2.4.16114
Metabolomics methods for the synthetic biology of secondary metabolism
10.1016/j.febslet.2012.02.008
Computational tools for the synthetic design of biochemical pathways
10.1038/nrmicro2717
A predicted physicochemically distinct sub-proteome associated with the intracellular organelle of the anammox bacterium Kuenenia stuttgartiensis
10.1186/1471-2164-11-299
Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus
10.1111/j.1751-7915.2010.00226.x
Denitrifying bacteria anaerobically oxidize methane in the absence of Archaea
10.1111/j.1462-2920.2008.01724.x
Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters
10.1016/j.cell.2014.06.034
Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products
10.1371/journal.pcbi.1003822
antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters
10.1093/nar/gkv437
Design-based re-engineering of biosynthetic gene clusters: plug-and-play in practice
10.1016/j.copbio.2013.03.006
Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block
10.1021/sb500368w
antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers
10.1093/nar/gkt449
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
10.1093/nar/gkr466
The Sequence of a 1.8-Mb Bacterial Linear Plasmid Reveals a Rich Evolutionary Reservoir of Secondary Metabolic Pathways
10.1093/gbe/evq013
MS/MS networking guided analysis of molecule and gene cluster families
10.1073/pnas.1303471110
Detecting Sequence Homology at the Gene Cluster Level with MultiGeneBlast
10.1093/molbev/mst025
Complete Genome Sequence of the Frog Pathogen Mycobacterium ulcerans Ecovar Liflandii
10.1128/jb.02132-12
NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity
10.1093/nar/gkr323
Mechanisms and Evolution of Control Logic in Prokaryotic Transcriptional Regulation
10.1128/mmbr.00037-08
Genomic mutational analysis of the impact of the classical strain improvement program on β-lactam producing Penicillium chrysogenum.
10.1186/s12864-015-2154-4
Leucanicidin and endophenasides result from methyl-rhamnosylation by the same tailoring enzymes in Kitasatospora sp. MBT66
10.1021/acschembio.5b00801
Computational strategies for genome-based natural product discovery and engineering in fungi
10.1016/j.fgb.2016.01.006
The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters
10.1093/nar/gkw960
Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides
10.1038/nmicrobiol.2016.197
Editorial: Synthetic biology and bioinformatics
10.1039/c6np90031c
plantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters
10.1093/nar/gkx305
Genome-based exploration of the specialized metabolic capacities of the genus Rhodococcus
10.1186/s12864-017-3966-1
Mining prokaryotes for antimicrobial compounds: from diversity to function
10.1093/femsre/fux014
Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters
10.1093/bib/bbx146
Standardization for natural product synthetic biology
10.1039/c6np00030d
Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways
10.1039/c6np00035e
Draft Genome Sequence of a Porcine Commensal, Rothia nasimurium , Encoding a Nonribosomal Peptide Synthetase Predicted To Produce the Ionophore Antibiotic Valinomycin
10.1128/genomea.00453-17
SANDPUMA: ensemble predictions of nonribosomal peptide chemistry reveal biosynthetic diversity across Actinobacteria
10.1093/bioinformatics/btx400
Collaborating with Undergraduates To Contribute to Biochemistry Community Resources
10.1021/acs.biochem.7b00872
Road MAPs to engineer host microbiomes.
10.1016/j.mib.2017.11.023
Genome-wide analysis of bacterial determinants of plant growth promotion and induced systemic resistance by Pseudomonas fluorescens.
10.1111/1462-2920.13927
Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution.
10.1073/pnas.1705567114
antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.
10.1093/nar/gkx319
Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.
10.1016/j.fgb.2016.01.012
Exploration and exploitation of the environment for novel specialized metabolites.
10.1016/j.copbio.2018.01.017
Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology
10.1128/mSystems.00182-17
Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics.
10.1016/j.chembiol.2018.02.008
HEx: A heterologous expression platform for the discovery of fungal natural products.
10.1126/sciadv.aar5459
luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria.
10.1128/msystems.00208-17
A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology.
10.1021/jacs.7b13292
Evolution and Diversity of Biosynthetic Gene Clusters in Fusarium.
10.3389/fmicb.2018.01158
Involvement of Burkholderiaceae and sulfurous volatiles in disease-suppressive soils.
10.1038/s41396-018-0186-x
Genomic Identification and Analysis of Specialized Metabolite Biosynthetic Gene Clusters in Plants Using PlantiSMASH.
10.1007/978-1-4939-7874-8_15
A standardized workflow for submitting data to the Minimum Information about a Biosynthetic Gene cluster (MIBiG) repository: prospects for research-based educational experiences
10.1186/s40793-018-0318-y
The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
10.1093/nar/gky1060
Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae
10.1101/463620
Mining bacterial genomes to reveal secret synergy
10.1074/jbc.H118.006669
Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters
10.1038/s42003-019-0333-6
Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae
10.1111/tpj.14292
A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters
10.1186/s13104-019-4222-3
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
10.1093/nar/gkz310
MolNetEnhancer: enhanced molecular networks by integrating metabolome mining and annotation tools
10.1101/654459
BiosyntheticSPAdes: Reconstructing Biosynthetic Gene Clusters From Assembly Graphs
10.1101/gr.243477.118
Genome Mining Approaches to Bacterial Natural Product Discovery
10.1016/b978-0-12-409547-2.14627-x
Computer-aided re-engineering of nonribosomal peptide and polyketide biosynthetic assembly lines
10.1039/C9NP00021F
PlantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters
10.1101/083535
MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools
10.3390/metabo9070144
Assessing Specialized Metabolite Diversity in the Cosmopolitan Plant Genus Euphorbia L.
10.3389/fpls.2019.00846
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
10.1126/science.aaw9285
MIBiG 2.0: a repository for biosynthetic gene clusters of known function
10.1093/nar/gkz882
A metabolic pathway for bile acid dehydroxylation by the gut microbiome
10.1101/758557
Coevolution-based prediction of protein-protein interactions in polyketide biosynthetic assembly lines
10.1101/669291
The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery
10.1021/acscentsci.9b00806
Cultivation and functional characterization of 79 planctomycetes uncovers their unique biology
10.1038/s41564-019-0588-1
Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia
10.1101/856955
Drivers of metabolic diversification: how dynamic genomic neighbourhoods generate new biosynthetic pathways in the Brassicaceae
10.1111/nph.16338
Microbial and volatile profiling of soils suppressive to Fusarium culmorum of wheat
10.1098/rspb.2019.2527
Computational genomic discovery of diverse gene clusters harboring Fe-S flavoenzymes in anaerobic gut microbiota
10.1101/2020.03.06.976126
RRE-Finder: A Genome-Mining Tool for Class-Independent RiPP Discovery
10.1101/2020.03.14.992123
Linking genomics and metabolomics to chart specialized metabolic diversity
10.1039/D0CS00162G
Computational genomic discovery of diverse gene clusters harbouring Fe-S flavoenzymes in anaerobic gut microbiota
10.1099/mgen.0.000373
ARTS 2.0: feature updates and expansion of the Antibiotic Resistant Target Seeker for comparative genome mining
10.1093/nar/gkaa374
Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products
10.1101/2020.05.19.104752
Ecology and genomics of Actinobacteria: new concepts for natural product discovery
10.1038/s41579-020-0379-y
The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms
10.1038/s42003-020-0993-2
BiG-SLiCE: A Highly Scalable Tool Maps the Diversity of 1.2 Million Biosynthetic Gene Clusters
10.1101/2020.08.17.240838
Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia
10.1074/jbc.RA120.013528
Microbial natural product databases: moving forward in the multi-omics era
10.1039/D0NP00053A
Author Correction: The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms
10.1038/s42003-020-01228-1
RRE-Finder: a Genome-Mining Tool for Class-Independent RiPP Discovery
10.1128/mSystems.00267-20
Author Correction: The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms
10.1038/s42003-020-01271-y
BiG-FAM: the biosynthetic gene cluster families database
10.1093/nar/gkaa812
Coevolution-based prediction of protein–protein interactions in polyketide biosynthetic assembly lines
10.1093/bioinformatics/btaa595
The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes
10.1093/nar/gkaa978
Pan-genome analysis and ancestral state reconstruction of class halobacteria: probability of a new super-order
10.1038/s41598-020-77723-6
BiG-MAP: an automated pipeline to profile metabolic gene cluster abundance and expression in microbiomes
10.1101/2020.12.14.422671
Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides
10.1371/journal.pbio.3001026
BiG-SLiCE: A highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters
10.1093/gigascience/giaa154
The year 2020 in natural product bioinformatics: an overview of the latest tools and databases
10.1039/D0NP00090F
Do size and shape matter? Exploring the interactions and the metabolome of the soil isolate Hylemonella gracilis
10.1101/2021.02.11.430889
A systematic analysis of metabolic pathways in the human gut microbiota
10.1101/2021.02.25.432841
Omics-based strategies to discover novel classes of RiPP natural products
10.1016/j.copbio.2020.12.008
Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria
10.1038/s41467-021-21163-x
The Surfactin-Like Lipopeptides From Bacillus spp.: Natural Biodiversity and Synthetic Biology for a Broader Application Range
10.3389/fbioe.2021.623701
Mining metagenomes for natural product biosynthetic gene clusters: unlocking new potential with ultrafast techniques
10.1101/2021.01.20.427441
Extracting the GEMs: Genotype, Environment, and Microbiome Interactions Shaping Host Phenotypes
10.3389/fmicb.2020.574053
A mammalian commensal of the oropharyngeal cavity produces antibiotic and antiviral valinomycin in vivo
10.21203/rs.3.rs-126949/v1
A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters
10.1016/j.chembiol.2020.11.009
cblaster: a remote search tool for rapid identification and visualisation of homologous gene clusters
10.1101/2020.11.08.370601
antiSMASH 6.0: improving cluster detection and comparison capabilities
10.1093/nar/gkab335
The gutSMASH web server: automated identification of primary metabolic gene clusters from the gut microbiota
10.1093/nar/gkab353
Mining genomes to illuminate the specialized chemistry of life
10.1038/s41576-021-00363-7
Dominant drivers of the human plasma metabolome
10.21203/rs.3.rs-688716/v1
A global survey of specialized metabolic diversity encoded in bacterial genomes
10.1101/2021.08.11.455920
cblaster: a remote search tool for rapid identification and visualization of homologous gene clusters
10.1093/bioadv/vbab016