High content screening identifies decaprenyl-phosphoribose 2′ epimerase as a target for intracellular antimycobacterial inhibitors
Christophe, Thierry
Jackson, Mary
Jeon, Hee Kyoung
Fenistein, Denis
Contreras-Dominguez, Monica
Kim, Jaeseung
Genovesio, Auguste
Carralot, Jean-Philippe
Ewann, Fanny
Kim, Eun Hye
Lee, Sae Yeon
Kang, Sunhee
Seo, Min Jung
Park, Eun Jung
Skovierova, Henrieta
Pham, Ha
Riccardi, Giovanna
Nam, Ji Youn
Marsollier, Laurent
Kempf, Marie
Joly-Guillou, Marie-Laure
Oh, Taegwon
Shin, Won Kyung
No, Zaesung
Nehrbass, Ulf
Brosch, Roland
Cole, Stewart T.
Brodin, Priscille
PLoS Pathogens, 2009-10
Giovanna RICCARDI
RICCARDI Giovanna
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Design, synthesis and evaluation of indole-2-carboxamides with pan anti-mycobacterial activity
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2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability
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Cytokinin Signaling in Mycobacterium tuberculosis
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Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos
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Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent
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Direct Inhibition of MmpL3 by Novel Antitubercular Compounds
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Characterization of Arabinosyl Transfer Reactions in the Biosynthesis of Mycobacterial Cell Envelope (Lipo)Polysaccharides
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2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain
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Indole-2-Carboxamides Are Active against Mycobacterium abscessus in a Mouse Model of Acute Infection
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Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular Mycobacterium tuberculosis
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New Approaches to Target the Mycolic Acid Biosynthesis Pathway for the Development of Tuberculosis Therapeutics
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MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections
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Mobile genetic elements and plasmids: tools for genetic studies
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Biochemical and microbiological evaluation of N-aryl urea derivatives against mycobacteria and mycobacterial hydrolases
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Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance
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Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in Mycobacterium tuberculosis
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Cloning and Partial Characterization of an Endo-alpha-(1 -> 6)-D-Mannanase Gene from Bacillus circulans
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Busting biofilms: free-living amoebae disrupt preformed methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium bovis biofilms
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Cell Surface Remodeling of Mycobacterium abscessus under Cystic Fibrosis Airway Growth Conditions
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Polysaccharide Succinylation Enhances the Intracellular Survival of Mycobacterium abscessus
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Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification
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MmpL3 Inhibition: A New Approach to Treat Nontuberculous Mycobacterial Infections
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Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell Envelope
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Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis
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Use of Synthetic Glycolipids to Probe the Number and Position of Arabinan Chains on Mycobacterial Arabinogalactan
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A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis
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Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives
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Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone
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Increased Virulence of Outer Membrane Porin Mutants of Mycobacterium abscessus
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Identifying Bacterial and Host Factors Involved in the Interaction of Mycobacterium bovis with the Bovine Innate Immune Cells
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An antitubercular prodrug leaves Mycobacterium tuberculosis facing a difficult choice, poisoning or starvation?
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Priscille Brodin
Brodin Priscille
ORCID: 0000-0003-0991-7344
Email: priscille.brodin@inserm.fr
How can nanoparticles contribute to antituberculosis therapy?
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Host-directed therapies offer novel opportunities for the fight against tuberculosis
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A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone
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Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections
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Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism
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Host-directed therapies offer novel opportunities for the fight against tuberculosis
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Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria
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Impact of pe_ pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis
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Phenotypic assays for Mycobacterium tuberculosis infection
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Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
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Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro
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Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization
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Mycolactone The amazing analgesic mycobacterial toxin
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STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection
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2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1
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Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo
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High content screening in chemical biology: overview and main challenges
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High-Content Screening Technology Combined with a Human Granuloma Model as a New Approach To Evaluate the Activities of Drugs against Mycobacterium tuberculosis
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Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system
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Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro
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Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action
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Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays
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A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening
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Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches
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Mycobacterial Toxin Induces Analgesia in Buruli Ulcer by Targeting the Angiotensin Pathways
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Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro
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A novel specific edge effect correction method for RNA interference screenings
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Discovery of Novel N-Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis
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Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors
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The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence
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Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis
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Ethionamide Boosters: Synthesis, Biological Activity, and Structure-Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors
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High-content screening in infectious diseases
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Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ
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High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling
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High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery
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Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting
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Automated High-Throughput siRNA Transfection in Raw 264.7 Macrophages: A Case Study for Optimization Procedure
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Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
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High Content Screening Identifies Decaprenyl-Phosphoribose 2 ' Epimerase as a Target for Intracellular Antimycobacterial Inhibitors
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Systematic Genetic Nomenclature for Type VII Secretion Systems
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Control of M-tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP
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Aquatic insects and transmission of Mycobacterium ulcerans
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Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis
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Benzofuro 3,2-f 1 benzopyrans: A new class of antitubercular agents
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Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence
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High frequency of CD4(+) T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection
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Evaluation of vaccines in the EU TB vaccine cluster using a guinea pig aerosol infection model of tuberculosis
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Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions
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Tuberculosis: from genome to vaccine
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Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex
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CD8(+)-T-cell responses of mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family
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Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
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A new evolutionary scenario for the Mycobacterium tuberculosis complex
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Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant
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Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides
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Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
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6-Oxocytidine containing oligonucleotides inhibit the HIV-1 integrase in vitro
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Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase
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Inhibition of the human immunodeficiency virus type 1 DNA integration by modified oligonucleotides
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Branched oligonucleotide-intercalator conjugate forming a parallel stranded structure inhibits HIV-1 integrase
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Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides
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Optimization of alternate-strand triple helix formation at the 5 '-TpA-3 ' and 5 '-ApT-3 ' junctions
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A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
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Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids
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ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton
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Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles
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Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis
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Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays
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Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages
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Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
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Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids
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Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry
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Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors
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Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis
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Proteomics of Mycobacterium infection: Moving towards a Better Understanding of Pathogen-Driven immunomodulation
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Synergy between circular bacteriocin AS-48 and ethambutol against Mycobacterium tuberculosis
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The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase
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Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis
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Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs
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Host-pathogen systems for early drug discovery against tuberculosis
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Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages
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Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
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Phenotypic assays for Mycobacterium tuberculosis infection
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A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening
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Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections
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Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation
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Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters
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Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis
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Mitochondrial Dynamics and Activity in Legionella-Infected Cells
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Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria
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Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication
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A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation
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Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls
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Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies.
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Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity.
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Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis.
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IRG1 controls immunometabolic host response and restricts intracellular Mycobacterium tuberculosis infection
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Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro.
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Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.
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Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.
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Benzofuro[3,2-f][1]benzopyrans: a new class of antitubercular agents.
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Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides.
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IRG1 controls immunometabolic host response and restricts intracellular Mycobacterium tuberculosis infection
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Large scale screening discovers clofoctol as an inhibitor of SARS-CoV-2 replication that reduces COVID-19-like pathology
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Carbapenem resistance and Acinetobacter baumannii in senegal: The paradigm of a common phenomenon in natural reservoirs
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Impact of faecal microbiota transplantation on mouse digestive colonization with two extensively resistant bacteria
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First report of blaNDM-1 -producing Acinetobacter baumannii isolated in Lebanon from civilians wounded during the Syrian war
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Mycobacterium ulcerans disease (Buruli ulcer) in Mali: A new potential African endemic country
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Establishment of quantitative PCR (qPCR) and culture laboratory facilities in a field hospital in Benin: 1-year results
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Iterative fecal microbiota transplantations for eradicating digestive colonization with carbapenemase-producing enterobacteriaceae: Is it worth it?
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Extrahuman epidemiology of Acinetobacter baumannii in Lebanon
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ARG-annot, a new bioinformatic tool to discover antibiotic resistance genes in bacterial genomes
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Synergistic activity of sulbactam combined with colistin against colistin-resistant Acinetobacter baumannii
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Disruption of Candida albicans IFF4 gene involves modifications of the cell electrical surface properties
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Confirmed case of buruli ulcer, Senegal, 2018
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A case report of Mycoplasma hominis brain abscess identified by MALDI-TOF mass spectrometry
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Clinical features of spontaneous partial healing during Mycobacterium ulcerans infection
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A rare case of Prosthetic Joint Infection associated with Coxiella burnetii
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Emergence of resistance to carbapenems in Acinetobacter baumannii in Europe: Clinical impact and therapeutic options
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Performance of penicillinase detection tests in Staphylococcus epidermidis: comparison of different phenotypic methods
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Disruption of the GPI protein-encoding gene IFF4 of Candida albicans results in decreased adherence and virulence
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Detection of Acinetobacter baumannii in human head and body lice from Ethiopia and identification of new genotypes
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Colistin-glycopeptide combinations against multidrug-resistant Acinetobacter baumannii in a mouse model of pneumonia
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Diversity of Acinetobacter species isolated from different environments in Lebanon: A nationwide study
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Evaluation of 16S rRNA gene PCR sensitivity and specificity for diagnosis of prosthetic joint infection: A prospective multicenter cross-sectional study
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The impact of performing bacterial identification and antimicrobial susceptibility testing on bronchoalveolar fluid cultures 24 h a day in a microbiology laboratory
10.1016/j.diagmicrobio.2014.07.009
Emergence of NDM-1 and OXA-72 producing Acinetobacter pittii clinical isolates in Lebanon
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Antibacterial activity against 224 clinical bacterial strains of JCA 250 and JCA 251 compounds containing essential oils provided from Aroma Technologies research,Étude de la sensibilité de 224 bactéries isolées d'infections hospitalières vis-à-vis des composés JCA 250 et JCA 251 à base d'huiles essentielles issus de la recherche Aroma Technologies
10.1016/j.patbio.2010.08.001
Stress conditions induced by carvacrol and cinnamaldehyde on Acinetobacter baumannii
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Class 1 integrons in Acinetobacter baumannii: a weak expression of gene cassettes to counterbalance the lack of LexA-driven integrase repression
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Semisynthetic Vitamin E Derivatives as Potent Antibacterial Agents against Resistant Gram-Positive Pathogens
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A case of guilt by association: Water bug bite incriminated in M. ulcerans infection
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Development of a Dry-Reagent-Based qPCR to Facilitate the Diagnosis of Mycobacterium ulcerans Infection in Endemic Countries
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Staphylococcus saprophyticus: Which beta-lactam?
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Rapid detection of carbapenem resistance in Acinetobacter baumannii using matrix-assisted laser desorption ionization-time of flight mass spectrometry
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Regional pneumococcus observatories: Evolution of antibiotic resistance and serotype distribution of Streptococcus pneumoniae isolated in France between 2009 and 2013,Observatoires régionaux du pneumocoque : Évolution de la résistance aux antibiotiques et des sérotypes de Streptococcus pneumoniae isolés en France entre 2009 et 2013
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High prevalence of contamination of sink drains with carbapenemase-producing Enterobacteriaceae in 4 intensive care units apart from any epidemic context
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Histopathological diagnosis of prosthetic joint infection: Does a threshold of 23 neutrophils do better than classification of the periprosthetic membrane in a prospective multicenter study?
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Wide spread of OXA-23-producing carbapenem-resistant Acinetobacter baumannii belonging to clonal complex II in different hospitals in Lebanon
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First report of Oxa-72-producing Acinetobacter calcoaceticus in Lebanon
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First report of endocarditis caused by a Pseudoclavibacter species
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Weight loss and abdominal pain in a 58-year-old-man,Un vent de panique et de questions
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Buruli ulcer acquired in Mali: A rare and atypical situation
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Molecular epidemiology of Acinetobacter baumannii in different hospitals in Tripoli, Lebanon using bla OXA-51-like sequence based typing
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Mycoplasma genitalium and Trichomonas vaginalis in France: a point prevalence study in people screened for sexually transmitted diseases
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Acinetobacter gandensis sp. nov. isolated from horse and cattle
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Synthesis, crystal structure, characterization of zinc(II), cadmium(II) complexes with 3-thiophene aldehyde thiosemicarbazone (3TTSCH). Biological activities of 3TTSCH and its complexes
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Diversity of Acinetobacter baumannii strains isolated in humans, companion animals, and the environment in Reunion Island: An exploratory study
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Assessment of the automated multiplex-PCR Unyvero i60 ITI® cartridge system to diagnose prosthetic joint infection: a multicentre study
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Molecular analysis of Acinetobacter baumannii strains isolated in Lebanon using four different typing methods
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Plasmid-mediated mcr-1 gene in colistin-resistant clinical isolates of Klebsiella pneumoniae in France and Laos
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Design and stability study of a paediatric oral solution of methotrexate 2 mg/ml
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Emergence of the OXA-23 carbapenemase-encoding gene in multidrug-resistant Acinetobacter baumannii clinical isolates from the Principal Hospital of Dakar, Senegal
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Comparative in vitro activity of Meropenem, Imipenem and Piperacillin/tazobactam against 1071 clinical isolates using 2 different methods: A French multicentre study
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Real-time sequencing to decipher the molecular mechanism of resistance of a clinical pan-drug-resistant Acinetobacter baumannii isolate from Marseille, France
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Invasive pneumococcal disease incidence in children and adults in France during the pneumococcal conjugate vaccine era: an interrupted time-series analysis of data from a 17-year national prospective surveillance study
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Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France
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Cell surface properties of two differently virulent strains of acinetobacter baumannii isolated from a patient
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Worldwide emergence of colistin resistance in Klebsiella pneumoniae from healthy humans and patients in Lao PDR, Thailand, Israel, Nigeria and France owing to inactivation of the PhoP/PhoQ regulator mgrB: An epidemiological and molecular study
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Assessment of the usefulness of performing bacterial identification and antimicrobial susceptibility testing 24 h a day in a clinical microbiology laboratory
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Biotyping of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates from France and Algeria Using MALDI-TOF MS
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High content screening identifies decaprenyl-phosphoribose 2′ epimerase as a target for intracellular antimycobacterial inhibitors
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DNA array analysis of Candida albicans gene expression in response to adherence to polystyrene
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How many samples and how many culture media to diagnose a prosthetic joint infection: A clinical and microbiological prospective multicenter study
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Mouse model of colonization of the digestive tract with Acinetobacter baumannii and subsequent pneumonia
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Acinetobacter pittii isolated more frequently than Acinetobacter baumannii in blood cultures: the experience of a French hospital
10.1016/j.jhin.2018.03.019
Auguste Genovesio
Genovesio Auguste
ORCID: 0000-0003-1877-5595
An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation.
10.1016/j.cub.2017.06.055
Smooth 2D manifold extraction from 3D image stack.
10.1038/ncomms15554
Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface.
10.1038/celldisc.2017.5
Detection and tracking of overlapping cell nuclei for large scale mitosis analyses.
10.1186/s12859-016-1030-9
High-throughput in vivo genotoxicity testing: an automated readout system for the somatic mutation and recombination test (SMART).
10.1371/journal.pone.0121287
Increasing the Content of High-Content Screening: An Overview.
10.1177/1087057114528537
Dimerization, oligomerization, and aggregation of human amyotrophic lateral sclerosis copper/zinc superoxide dismutase 1 protein mutant forms in live cells.
10.1074/jbc.m113.542613
Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment.
10.1177/1087057113503553
Development of a multiplex phenotypic cell-based high throughput screening assay to identify novel hepatitis C virus antivirals.
10.1016/j.antiviral.2013.04.020
Transcription sites are developmentally regulated during the asexual cycle of Plasmodium falciparum.
10.1371/journal.pone.0055539
An image-based drug susceptibility assay targeting the placental sequestration of Plasmodium falciparum-infected erythrocytes.
10.1371/journal.pone.0041765
An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages.
10.1371/journal.pntd.0001671
A novel specific edge effect correction method for RNA interference screenings.
10.1093/bioinformatics/btr648
A high-content subtractive screen for selecting small molecules affecting internalization of GPCRs.
10.1177/1087057111427347
Quantification of protein interaction in living cells by two-photon spectral imaging with fluorescent protein fluorescence resonance energy transfer pair devoid of acceptor bleed-through.
10.1002/cyto.a.21150
Automated genome-wide visual profiling of cellular proteins involved in HIV infection.
10.1177/1087057111415521
Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection.
10.1371/journal.pone.0019733
High content cellular microarray for automated drug target deconvolution.
10.1186/1753-6561-5-s1-p76
Development of a cell-based high throughput assay system and IN-house image analysis software for screening of active compounds against dengue virus.
10.1186/1753-6561-5-s1-p46
A high-throughput cell-based assay to screen for drugs affecting PfEMP1 transport to RBC surface.
10.1186/1753-6561-5-s1-p15
High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling.
10.1371/journal.ppat.1001100
Contextual automated 3D analysis of subcellular organelles adapted to high-content screening.
10.1177/1087057110374993
Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds.
10.1371/journal.pntd.0000675
A modified fluorescence in situ hybridization protocol for Plasmodium falciparum greatly improves nuclear architecture conservation.
10.1016/j.molbiopara.2010.04.006
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors.
10.1371/journal.ppat.1000645
In vivo colocalisation of oskar mRNA and trans-acting proteins revealed by quantitative imaging of the Drosophila oocyte.
10.1371/journal.pone.0006241
Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure.
10.1177/1087057108328762
Neuron branch detection and description using random walk.
10.1109/iembs.2009.5334083
A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening.
10.1002/cyto.a.20627
Automated nuclear analysis of Leishmania major telomeric clusters reveals changes in their organization during the parasite's life cycle.
10.1371/journal.pone.0002313
Three-dimensional point spread function model for line-scanning confocal microscope with high-aperture objective.
10.1111/j.1365-2818.2007.01844.x
High-content classification of nucleocytoplasmic import or export inhibitors.
10.1177/1087057107301319
Quantitative four-dimensional tracking of cytoplasmic and nuclear HIV-1 complexes.
10.1038/nmeth928
Cerebral microcirculation shear stress levels determine Neisseria meningitidis attachment sites along the blood-brain barrier.
10.1084/jem.20060482
SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope.
10.1038/nature04752
Multiple particle tracking in 3-D+t microscopy: method and application to the tracking of endocytosed quantum dots.
10.1109/tip.2006.872323
Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region.
10.1083/jcb.200505159
Automated Confocal Microscope Bias Correction
10.1063/1.2361251
Active vector graph for regularized tesselation
10.1109/icip.2009.5414154
IM.Grid, a Grid computing approach for Image Mining of High Throughput-High Content Screening
10.1109/grid.2008.4662818
SUPPORT VECTOR MACHINES FOR AUTOMATIC DETECTION OF TUBERCULOSIS BACTERIA IN CONFOCAL MICROSCOPY IMAGES
10.1109/isbi.2007.356794
A New Color Representation for Intensity Independent Pixel Classification in Confocal Microscopy Images
10.1007/978-3-540-74607-2_54
3D Mumford-Shah Based Active Mesh
10.1007/11892755_21
Tracking fluroescent spots in biological video microscopy
10.1117/12.478040
Automated Identification and Analysis of Visual Micro-experiments on Cellular Microarray
10.1007/978-3-642-25547-2_3
3D Automated Nuclear Morphometric Analysis Using Active Meshes
10.1007/978-3-540-75286-8_34
Correction
10.1083/jcb.20050515920060227c
A method for discontinuous neurite reconstruction based on diffusion tensor, Hessian eigenvector, and diffused gradient vector fields
10.1109/icip.2011.6115702
Cerebral microcirculation shear stress levels determineNeisseria meningitidisattachment sites along the blood–brain barrier
10.1083/jcb1744oia7
mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis
10.1242/jcs.201640
Biased Image Correction Based on Empirical Mode Decomposition
10.1109/icip.2007.4379009
Inhomogeneous deconvolution in a biological images context
10.1109/isbi.2008.4541103
BIAS FREE FEATURES DETECTION FOR HIGH CONTENT SCREENING
10.1109/isbi.2007.356940
Split and merge data association filter for dense multi-target tracking
10.1109/icpr.2004.1333863
Interacting multiple model based method to track moving fluorescent biological spots
10.1109/isbi.2004.1398769
3D spatial drift correction using Kalman filtering for fluorescence based imaging
10.1109/isbi.2009.5193253
Calibrated mitotic oscillator drives motile ciliogenesis
10.1126/science.aan8311
Monitored eCLIP: high accuracy mapping of RNA-protein interactions.
10.1093/nar/gky858
DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis.
10.7554/eLife.37892
Active fluctuations modulate gene expression in mouse oocytes
10.1101/347310
Ependymal cilia beating induces an actin network to protect centrioles against shear stress.
10.1038/s41467-018-04676-w
High-throughput optical mapping of replicating DNA
10.1101/239251
Compound Functional Prediction Using Multiple Unrelated Morphological Profiling Assays.
10.1177/2472630317740831
mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis.
10.1242/dev.138271
ALFA: annotation landscape for aligned reads
10.1186/s12864-019-5624-2
Coordination of transcriptional and translational regulations in human epithelial cells infected by Listeria monocytogenes
10.1101/775148
PySpacell: A Python Package for Spatial Analysis of Cell Images
10.1002/cyto.a.23955
In vivo large-scale analysis of Drosophila neuronal calcium traces by automated tracking of single somata
10.1038/s41598-020-64060-x
Coordination of transcriptional and translational regulations in human epithelial cells infected by Listeria monocytogenes
10.1080/15476286.2020.1777380
Unraveling spatial cellular pattern by computational tissue shuffling
10.1038/s42003-020-01323-3
Genome wide natural variation of H3K27me3 selectively marks genes predicted to be important for cell differentiation in Phaeodactylum tricornutum
10.1101/2019.12.26.888800
Genome wide natural variation of H3K27me3 selectively marks genes predicted to be important for cell differentiation in Phaeodactylum tricornutum
10.1111/nph.17129
Marie Laure Joly-Guillou
Joly-Guillou Marie Laure
/ Joly-Guillou ML
/ Joly M
ORCID: 0000-0003-2593-6684
Diversity of Acinetobacter species isolated from different environments in Lebanon: a nationwide study.
10.2217/fmb-2016-0082
Siderophores in Cloud Waters and Potential Impact on Atmospheric Chemistry: Production by Microorganisms Isolated at the Puy de Dome Station.
10.1021/acs.est.6b02335
Stress Conditions Induced by Carvacrol and Cinnamaldehyde on Acinetobacter baumannii.
10.3389/fmicb.2016.01133
First report of carbapenemase-producing Acinetobacter baumannii carriage in pets from the community in France.
10.1016/j.ijantimicag.2016.03.012
Emergence of NDM-1 and OXA-72 producing Acinetobacter pittii clinical isolates in Lebanon.
10.1016/j.nmni.2016.04.005
[SFBC guidelines on critical care testing].
10.1684/abc.2015.1113
Lipid-Based Liquid Crystals As Carriers for Antimicrobial Peptides: Phase Behavior and Antimicrobial Effect.
10.1021/acs.langmuir.6b00338
Demonstration of the interactions between aromatic compound-loaded lipid nanocapsules and Acinetobacter baumannii bacterial membrane.
10.1016/j.ijpharm.2016.03.033
Peritonsillar abscess (PTA): clinical characteristics, microbiology, drug exposures and outcomes of a large multicenter cohort survey of 412 patients hospitalized in 13 French university hospitals.
10.1007/s10096-016-2609-9
Reservoirs of Non-baumannii Acinetobacter Species.
10.3389/fmicb.2016.00049
Synergistic interactions between doxycycline and terpenic components of essential oils encapsulated within lipid nanocapsules against gram negative bacteria.
10.1016/j.ijpharm.2015.11.042
The role of acoustic signaling for spacing and group coordination in a nocturnal, pair-living primate, the western woolly lemur (Avahi occidentalis).
10.1002/ajpa.22898
First report of Oxa-72-producing Acinetobacter calcoaceticus in Lebanon.
10.1016/j.nmni.2015.11.010
Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets.
10.1111/irv.12356
The axon guidance molecule semaphorin 3F is a negative regulator of tumor progression and proliferation in ileal neuroendocrine tumors.
10.18632/oncotarget.5481
Using Vitek MALDI-TOF mass spectrometry to identify species belonging to the Acinetobacter calcoaceticus-Acinetobacter baumannii complex: a relevant alternative to molecular biology?
10.1016/j.diagmicrobio.2015.06.009
Diversity of Acinetobacter baumannii strains isolated in humans, companion animals, and the environment in Reunion Island: an exploratory study.
10.1016/j.ijid.2015.05.012
Molecular epidemiology of Acinetobacter baumannii in different hospitals in Tripoli, Lebanon using bla(OXA-51-like) sequence based typing.
10.1186/s12866-015-0441-5
Retrospective detection of the hidden spread of OXA-48-producing Klebsiella pneumoniae in a French teaching hospital.
10.1016/j.jinf.2015.05.004
[Prevalence of Clostridium difficile infection in hospitalized patients with diarrhea: results of a French prospective multicenter bi-annual point prevalence study].
10.1016/j.lpm.2014.09.021
Extrahuman epidemiology of Acinetobacter baumannii in Lebanon.
10.1128/aem.03824-14
Molecular analysis of Acinetobacter baumannii strains isolated in Lebanon using four different typing methods.
10.1371/journal.pone.0115969
A case report of Mycoplasma hominis brain abscess identified by MALDI-TOF mass spectrometry.
10.1016/j.ijid.2014.08.004
Escherichia coli antibiotic resistance in emergency departments. Do local resistance rates matter?
10.1007/s10096-014-2264-y
Escherichia coli bacteraemia in pregnant women is life-threatening for foetuses.
10.1111/1469-0691.12742
Escherichia coli bacteremia in children: age and portal of entry are the main predictors of severity.
10.1097/inf.0000000000000309
The impact of performing bacterial identification and antimicrobial susceptibility testing on bronchoalveolar fluid cultures 24 h a day in a microbiology laboratory.
10.1016/j.diagmicrobio.2014.07.009
Colistin, rifampicin, and meropenem administered as single agents in a model of pneumonia caused by a carbapenem-resistant Acinetobacter baumannii.
10.1016/j.jinf.2014.07.003
First report of endocarditis caused by a Pseudoclavibacter species.
10.1128/jcm.01388-14
Escherichia coli bacteraemia in adults: age-related differences in clinical and bacteriological characteristics, and outcome.
10.1017/s0950268814000211
First report of blaNDM-1-producing Acinetobacter baumannii isolated in Lebanon from civilians wounded during the Syrian war.
10.1016/j.ijid.2014.01.004
High prevalence of closely-related Acinetobacter baumannii in pets according to a multicentre study in veterinary clinics, Reunion Island.
10.1016/j.vetmic.2014.01.042
Current molecular methods in epidemiological typing of Acinetobacter baumannii.
10.2217/fmb.14.63
Discordance in the minimal inhibitory concentrations of ertapenem for Enterobacter cloacae: Vitek 2 system versus Etest and agar dilution methods.
10.1016/j.ijid.2013.09.006
Complexity of Escherichia coli bacteremia pathophysiology evidenced by comparison of isolates from blood and portal of entry within single patients.
10.1016/j.ijmm.2013.07.002
Reservoirs of Acinetobacter baumannii outside the hospital and potential involvement in emerging human community-acquired infections.
10.1016/j.ijid.2013.03.021
Using a qualitative study to understand the failure of a strategy implemented for improving hand hygiene adherence in 4 intensive care units.
10.1086/669875
[Extra-digestive reservoir of extended-spectrum beta-lactamase producing Enterobacteriaceae in non-infected patients: a study based on the systematic searching in urine and other clinical samples].
10.1684/abc.2012.0762
[Urinary tract infection caused by Haemophilus influenzae in 3 children with uropathies].
10.1016/j.arcped.2012.05.016
Investigation of Acinetobacter baumannii resistance to carbapenems in Marseille hospitals, south of France: a transition from an epidemic to an endemic situation.
10.1111/j.1600-0463.2012.02935.x
Cell surface properties of two differently virulent strains of Acinetobacter baumannii isolated from a patient.
10.1139/w11-131
Differences in Acinetobacter baumannii strains and host innate immune response determine morbidity and mortality in experimental pneumonia.
10.1371/journal.pone.0030673
[In vitro activity of tigecycline on 760 bacterial strains isolated in the hospital university of Angers--2006-2009 TEST study].
10.1016/j.patbio.2011.11.008
[Emerging Acinetobacter baumannii infections and factors favouring their occurrence].
10.1016/j.patbio.2011.08.002
Relative contribution of three main virulence factors in Pseudomonas aeruginosa pneumonia.
10.1097/ccm.0b013e31821e899f
Correlation between glove use practices and compliance with hand hygiene in a multicenter study with elderly patients.
10.1016/j.ajic.2011.05.008
[Improving the level of understanding of English of medical students is possible. Results of a systematic assessment policy].
10.1016/j.lpm.2011.04.009
Measurement of hand hygiene compliance and gloving practices in different settings for the elderly considering the location of hand hygiene opportunities during patient care.
10.1016/j.ajic.2010.08.023
Impact of improving glove usage on the hand hygiene compliance.
10.1016/j.ajic.2010.08.022
Impact of screening and identifying methicillin-resistant Staphylococcus aureus carriers on hand hygiene compliance in 4 intensive care units.
10.1016/j.ajic.2010.10.029
Bacteraemia caused by third-generation cephalosporin-resistant Escherichia coli in France: prevalence, molecular epidemiology and clinical features.
10.1111/j.1469-0691.2010.03298.x
Impact of a multi-faceted training intervention on the improvement of hand hygiene and gloving practices in four healthcare settings including nursing homes, acute-care geriatric wards and physical rehabilitation units.
10.1111/j.1365-2702.2011.03704.x
Host factors and portal of entry outweigh bacterial determinants to predict the severity of Escherichia coli bacteremia.
10.1128/jcm.01902-10
[Antibacterial activity against 224 clinical bacterial strains of JCA 250 and JCA 251 compounds containing essential oils provided from Aroma Technologies research].
10.1016/j.patbio.2010.08.001
Epidemiology and antimicrobial resistance of Streptococcus pneumoniae in France in 2007: data from the pneumococcus surveillance network.
10.1089/mdr.2010.0031
Rates of adherence to hand hygiene and gloving practices in 2 French rehabilitation hospitals by differentiation between single contacts and series of successive contacts with patients or the environment.
10.1086/655436
Comparative in vitro activity of Meropenem, Imipenem and Piperacillin/tazobactam against 1071 clinical isolates using 2 different methods: a French multicentre study.
10.1186/1471-2334-10-72
Curbing methicillin-resistant Staphylococcus aureus in 38 French hospitals through a 15-year institutional control program.
10.1001/archinternmed.2010.32
[Assessing the usefulness of a permanently opened clinical microbiology laboratory].
10.1016/j.medmal.2009.10.011
[Pays de la Loire Pneumococcus Observatory: antimicrobial resistance of Streptococcus pneumoniae in 2007].
10.1016/j.patbio.2009.06.009
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors.
10.1371/journal.ppat.1000645
The virulence variability of different Acinetobacter baumannii strains in experimental pneumonia.
10.1016/j.jinf.2009.09.004
Assessment of the usefulness of performing bacterial identification and antimicrobial susceptibility testing 24 h a day in a clinical microbiology laboratory.
10.1111/j.1469-0691.2009.03044.x
Carriage of methicillin-resistant Staphylococcus aureus in home care settings: prevalence, duration, and transmission to household members.
10.1001/archinternmed.2009.217
Measurement and interpretation of hand hygiene compliance rates: importance of monitoring entire care episodes.
10.1016/j.jhin.2009.03.025
[Surgical-site infections following varicose vein surgery according to a continuous series of 408 interventions in a teaching hospital].
10.1016/j.patbio.2009.03.006
Association between an index of consumption of hand-rub solution and the incidence of acquired meticillin-resistant Staphylococcus aureus in an intensive care unit.
10.1016/j.jhin.2008.10.024
Factors affecting compliance with glove removal after contact with a patient or environment in four intensive care units.
10.1016/j.jhin.2008.11.005
[Activity of tigecycline against pathogen bacteria isolated in respiratory infectious disease in Europe. TEST study 2004-2007].
10.1016/j.patbio.2008.08.006
Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis.
10.1371/journal.ppat.0030062
[Infection and variceal bleeding in cirrhosis].
10.1016/s0399-8320(07)89324-9
[Using a 48-hour delay from admission to the first positive culture without any other consideration: an accurate method to differentiate acquired and imported methicillin-resistant Staphylococcus aureus?]
10.1016/j.patbio.2006.10.003
Impact of the reinforcement of a methicillin-resistant Staphylococcus aureus control programme: a 3-year evaluation by several indicators in a French university hospital.
10.1007/s10654-006-9024-y
Impact of selective screening in the emergency department on meticillin-resistant Staphylococcus aureus control programmes.
10.1016/j.jhin.2006.02.020
Consideration of age at admission for selective screening to identify methicillin-resistant Staphylococcus aureus carriers to control dissemination in a medical ward.
10.1016/j.ajic.2006.01.001
Evaluation of a strategy of screening multiple anatomical sites for methicillin-resistant Staphylococcus aureus at admission to a teaching hospital.
10.1086/500627
Control and outcome of a large outbreak of colonization and infection with glycopeptide-intermediate Staphylococcus aureus in an intensive care unit.
10.1086/498898
Clinical impact and pathogenicity of Acinetobacter.
10.1111/j.1469-0691.2005.01227.x
Influence of fluoride, hydrogen peroxide and lactic acid on the corrosion resistance of commercially pure titanium.
10.1016/j.actbio.2005.09.004
Estimation of methicillin-resistant Staphylococcus aureus transmission by considering colonization pressure at the time of hospital admission.
10.1016/j.jhin.2004.10.008
Impact of screening for MRSA carriers at hospital admission on risk-adjusted indicators according to the imported MRSA colonization pressure.
10.1016/j.jhin.2004.09.028
[Role of the laboratory of microbiology in empirical therapeutic strategy]
10.1016/j.annfar.2004.05.011
Accuracy of delayed (24 hours) processing of bronchoalveolar lavage for diagnosing bacterial pneumonia.
10.1097/01.ccm.0000114813.85853.ea
The impact of methicillin resistance on the outcome of poststernotomy mediastinitis due to Staphylococcus aureus.
10.1086/381890
Carriage of methicillin-resistant Staphylococcus aureus among hospital employees: prevalence, duration, and transmission to households.
10.1086/502360
Infectious and inflammatory dissemination are affected by ventilation strategy in rats with unilateral pneumonia.
10.1007/s00134-003-2147-7
[Treatment of genital infections in gynecology]
10.1016/s1297-9589(01)00245-4
Accuracy of delayed cultures of plugged telescoping catheter samples for diagnosing bacterial pneumonia.
10.1097/00003246-200107000-00003
An outbreak of imipenem-resistant Acinetobacter baumannii in critically ill surgical patients.
10.1086/501822
In vivo activity of levofloxacin alone or in combination with imipenem or amikacin in a mouse model of Acinetobacter baumannii pneumonia.
10.1093/jac/46.5.827
Nosocomial bacteremia in HIV patients: the role of peripheral venous catheters.
10.1086/501766
Control of staphylococcal adhesion to polymethylmethacrylate and enhancement of susceptibility to antibiotics by poloxamer 407.
10.1128/aac.44.4.1093-1096.2000
Nucleotide sequence of the bla(RTG-2) (CARB-5) gene and phylogeny of a new group of carbenicillinases.
10.1128/aac.44.4.1070-1074.2000
Microbiological evaluation of central venous catheter administration hubs.
10.1086/501696
Control of a prolonged outbreak of extended-spectrum beta-lactamase-producing enterobacteriaceae in a university hospital.
10.1086/313511
Practical recommendations for the drug treatment of bacterial infections of the male genital tract including urethritis, epididymitis and prostatitis.
10.2165/00003495-199957050-00007
First case of Salmonella hirschfeldii (paratyphi C) infection of a prosthetic hip.
10.1111/j.1469-0691.1998.tb00676.x
Nosocomial pneumonia in patients with acute respiratory distress syndrome.
10.1164/ajrccm.157.4.9708057
Ventilator-associated pneumonia caused by potentially drug-resistant bacteria.
10.1164/ajrccm.157.2.9705064
Usefulness of quantitative cultures of BAL fluid for diagnosing nosocomial pneumonia in ventilated patients.
10.1378/chest.111.2.411
Characterisation of DNA gyrase and measurement of drug accumulation in clinical isolates of Acinetobacter baumannii resistant to fluoroquinolones.
10.1093/jac/38.6.1079
Bactericidal in-vitro activity of beta-lactams and beta-lactamase inhibitors, alone or associated, against clinical strains of Acinetobacter baumannii: effect of combination with aminoglycosides.
10.1093/jac/36.4.619
Role of quantitative cultures of endotracheal aspirates in the diagnosis of nosocomial pneumonia.
10.1164/ajrccm.152.1.7599831
In-vitro activity of sparfloxacin, pefloxacin, ciprofloxacin and temafloxacin against clinical isolates of Acinetobacter spp.
10.1093/jac/29.4.466
Hospital infection with Acinetobacter spp.: an increasing problem.
10.1016/0195-6701(91)90030-c
A study of the relationships between antibiotic resistance phenotypes, phage-typing and biotyping of 117 clinical isolates of Acinetobacter spp.
10.1016/0195-6701(90)90048-s
Novel carbenicillin-hydrolyzing beta-lactamase (CARB-5) from Acinetobacter calcoaceticus var. anitratus.
10.1016/0378-1097(89)90456-4
Roland Brosch
Brosch Roland
ORCID: 0000-0003-2587-3863
Mycobacterium tuberculosis Meets the Cytosol: The Role of cGAS in Anti-mycobacterial Immunity.
10.1016/j.chom.2015.05.017
Insights on the emergence of Mycobacterium tuberculosis from the analysis of Mycobacterium kansasii
10.1093/gbe/evv035
Mycobacterial Pathogenomics and Evolution.
10.1128/microbiolspec.MGM2-0025-2013
Release of mycobacterial antigens
10.1111/imr.12251
Mycobacterium abscessus phospholipase C expression is induced during coculture within amoebae and enhances M. abscessus virulence in mice
10.1128/IAI.02032-14
Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system
10.1016/j.vaccine.2015.03.083
Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations
10.1038/srep15443
ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection
10.1016/j.tube.2015.02.019
Developing whole mycobacteria cell vaccines for tuberculosis: Workshop proceedings, Max Planck Institute for Infection Biology, Berlin, Germany, July 9, 2014
10.1016/j.vaccine.2015.03.056
Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo
10.1371/journal.ppat.1004650
Bovine tubercle bacilli: evolution associated with loss of transmission capacity in humans | Les bacilles de la tuberculose bovine - Une évolution aux dépens de la transmissibilité chez l'homme
10.1051/medsci/20153102003
Mycobacterium tuberculosis Exploits Asparagine to Assimilate Nitrogen and Resist Acid Stress during Infection
10.1371/journal.ppat.1003928
Mycobacterium tuberculosis evolutionary pathogenesis and its putative impact on drug development
10.2217/fmb.14.70
Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator
10.1073/pnas.1406693111
Bacillus calmette-guérin strain differences have an impact on clinical outcome in bladder cancer immunotherapy
10.1016/j.eururo.2014.02.061
A Specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies whiB6 as a novel ESX-1 component
10.1128/IAI.01824-14
A glimpse into the past and predictions for the future: The molecular evolution of the tuberculosis agent
10.1111/mmi.12720
TBCAP; Tuberculosis annotation project
10.1016/j.tube.2012.11.013
Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus
10.1111/mmi.12387
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis
10.1038/ng.2517
ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis
10.1111/cmi.12169
Characterization of Mycobacterium orygis
10.3201/eid1903.121005
The ESX-5 Associated eccB5-eccC5 Locus Is Essential for Mycobacterium tuberculosis Viability
10.1371/journal.pone.0052059
Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion-encoded PE-PPE proteins predicts vaccine potential
10.1016/j.chom.2012.03.003
Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death
10.1371/journal.ppat.1002507
Multidrug-resistant tuberculosis in admitted patients at a tertiary referral hospital of Bangladesh
10.1371/journal.pone.0040545
Molecular epidemiology of tuberculosis in rural Matlab, Bangladesh
10.5588/ijtld.11.0426
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
10.1111/j.1462-5822.2012.01799.x
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells
10.4161/auto.20881
Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation
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Benzothiazinones Kill Mycobacterium tuberculosis by blocking Arabinan synthesis
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Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
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ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity
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Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence
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Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against Oxidative Stress
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Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity
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ESAT-6 proteins: Protective antigens and virulence factors?
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Cell Envelope Protein PPE68 Contributes to Mycobacterium tuberculosis RD1 Immunogenicity Independently of A 10-Kilodalton Culture Filtrate Protein and ESAT-6
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Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
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Rapid and simple approach for identification of Mycobacterium tuberculosis complex isolates by PCR-based genomic deletion analysis
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Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
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Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant
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A new evolutionary scenario for the Mycobacterium tuberculosis complex
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The evolution of mycobacterial pathogenicity: Clues from comparative genomics
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Genomics of Mycobacterium bovis
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Tools for the population genomics of the tubercle bacilli
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Comparative genomics of the leprosy and tubercle bacilli
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Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays
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Analysis of the proteome of Mycobacterium tuberculosis in silico
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The high-pathogenicity island of Yersinia pseudotuberculosis can be inserted into any of the three chromosomal asn tRNA genes
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Deciphering the biology of mycobacterium tuberculosis from the complete genome sequence
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Genomic fingerprinting of 80 strains from the WHO multicenter international typing study of Listeria monocytogenes via pulsed-field gel electrophoresis (PFGE)
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Characterization of Listeria strains isolated from soft cheese
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Listeriosis outbreak in France in 1992. Microbial data | Epidémie de listériose en France en 1992 aspects microbiologiques
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Use of pulsed field gel electrophoresis to compare large DNA-restriction fragments of Listeria monocytogenes strains belonging to serogroups 1/2 and 3
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Subtyping of Listeria monocytogenes serovar 4b by use of low-frequency-cleavage restriction endonucleases and pulsed-field gel electrophoresis
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Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions
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Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis
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The BCG Strain Pool: Diversity Matters.
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Genome-wide mosaicism within Mycobacterium abscessus: evolutionary and epidemiological implications.
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Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria
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Comparative Genomics and Evolution of Mycobacterium bovis BCG
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The Mycobacteria: a Postgenomic View
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Genomics ofMycobacterium Tuberculosis and Mycobacterium Leprae
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Genomics of the Mycobacterium tuberculosis complex and Mycobacterium leprae
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ESX secretion systems: mycobacterial evolution to counter host immunity
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Resistance to thiacetazone derivatives active against Mycobacterium abscessus involves mutations in the MmpL5 transcriptional repressor MAB_4384
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ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis.
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Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis
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PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
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Predicting susceptibility to tuberculosis based on gene expression profiling in dendritic cells
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Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
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Evolution of virulence in the Mycobacterium tuberculosis complex
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The Macrophage: A Disputed Fortress in the Battle against Mycobacterium tuberculosis
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Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis
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Discovery of the type VII ESX-1 secretion needle?
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Identification of genes required forMycobacterium abscessusgrowth in vivo with a prominent role of the ESX-4 locus
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Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions
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Horizontal acquisition of a hypoxia-responsive molybdenum cofactor biosynthesis pathway contributed to Mycobacterium tuberculosis pathoadaptation
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The Biology and Epidemiology of Mycobacterium canettii
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Targeting Type VII/ESX Secretion Systems for Development of Novel Antimycobacterial Drugs
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Taxonomic Diversity of Pseudomonads Revealed by Computer-interpretation of Ribotyping Data
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Comparative genomics of the mycobacteria
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Single Cell Measurements of Vacuolar Rupture Caused by Intracellular Pathogens
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Type VII Secretion Systems in Gram-Positive Bacteria
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Genomic characterization of Mycobacterium tuberculosis lineage 7 and a proposed name: ‘Aethiops vetus’
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Leprosy in red squirrels
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CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection
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pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence
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A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence ofMycobacterium marinumin multiple hosts
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The PE and PPE Protein Families of Mycobacterium tuberculosis
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Influence of ESAT-6 Secretion System 1 (RD1) of Mycobacterium tuberculosis on the Interaction between Mycobacteria and the Host Immune System
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Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors
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ESAT-6–dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo
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Cutting-edge science and the future of tuberculosis control
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ESAT-6 and the Mycobacterial ESX Secretion Systems
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RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection
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Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity
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New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach
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Update on the virulence factors of the obligate pathogen Mycobacterium tuberculosis and related tuberculosis-causing mycobacteria
10.1016/j.meegid.2018.12.013
Shared Pathogenomic Patterns Characterize a New Phylotype, Revealing Transition toward Host-Adaptation Long before Speciation of Mycobacterium tuberculosis
10.1093/gbe/evz162
Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis.
10.1021/acsnano.8b07902
Mycobacterial virulence: impact on immunogenicity and vaccine research
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TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages
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Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis
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ESX/Type VII Secretion Systems—An Important Way Out for Mycobacterial Proteins
10.1128/microbiolspec.psib-0029-2019
ESX-4, un système de sécrétion mycobactérien ancestral, essentiel pour la croissance de Mycobacterium abscessus dans les phagocytes environnementaux et humains
10.1051/medsci/2018196
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages
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A systematic approach to simultaneously evaluate safety, immunogenicity, and efficacy of novel tuberculosis vaccination strategies
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Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro–American genetic background confers optimal vaccine potential
10.1016/j.ebiom.2020.102761
Mucosal delivery of ESX-1–expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes
10.1073/pnas.2003235117
Le BCG : histoire moléculaire et nouvelles perspectives
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Breaching the phagosome, the case of the tuberculosis agent
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Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts
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The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection
10.7554/elife.55692
IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria In Vivo
10.1128/mSphere.00153-21
ESX-1-Independent Horizontal Gene Transfer by Mycobacterium tuberculosis Complex Strains
10.1128/mBio.00965-21
Evolution of Mycobacterium tuberculosis : New Insights into Pathogenicity and Drug Resistance
10.1128/microbiolspec.tbtb2-0020-2016
Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors
10.3389/fcimb.2020.00420
Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli
10.1038/s41564-021-00938-4
Marsollier Laurent
Laurent Marsollier
ORCID: 0000-0001-5497-5995
High antibody titres induced by protein subunit vaccines using Mycobacterium ulcerans antigens Hsp18 and MUL_3720 with a TLR-2 agonist fail to protect against Buruli ulcer in mice.
10.7717/peerj.9659
Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway.
10.1038/s42003-020-0920-6
Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model.
10.1128/iai.00753-19
Senegal, a new potential endemic country for Buruli ulcer?
10.1016/j.ijid.2019.09.020
Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls.
10.3390/toxins11090516
Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters.
10.3389/fphar.2019.00378
Microdeletion on chromosome 8p23.1 in a familial form of severe Buruli ulcer.
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The potent effect of mycolactone on lipid membranes.
10.1371/journal.ppat.1006814
ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.
10.15252/embr.201744371
A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.
10.3390/toxins9070227
Mouse model of colonization of the digestive tract with Acinetobacter baumannii and subsequent pneumonia.
10.2217/fmb-2016-0203
Ecology and Feeding Habits Drive Infection of Water Bugs with Mycobacterium ulcerans.
10.1007/s10393-017-1228-y
Draft Genome Sequence of Mycobacterium ulcerans S4018 Isolated from a Patient with an Active Buruli Ulcer in Benin, Africa.
10.1128/genomea.00248-17
An Optimized Method for Extracting Bacterial RNA from Mouse Skin Tissue Colonized by Mycobacterium ulcerans.
10.3389/fmicb.2017.00512
Multiple Introductions and Recent Spread of the Emerging Human Pathogen Mycobacterium ulcerans across Africa.
10.1093/gbe/evx003
Deforestation-driven food-web collapse linked to emerging tropical infectious disease, Mycobacterium ulcerans.
10.1126/sciadv.1600387
Chitin promotes Mycobacterium ulcerans growth.
10.1093/femsec/fiw067
Molecular Species Delimitation and Morphology of Aquatic and Sub-Aquatic Bugs (Heteroptera) in Cameroon.
10.1371/journal.pone.0154905
FVB/N Mice Spontaneously Heal Ulcerative Lesions Induced by Mycobacterium ulcerans and Switch M. ulcerans into a Low Mycolactone Producer.
10.4049/jimmunol.1502194
[Mycolactone: the amazing analgesic mycobacterial toxin].
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Seasonal Patterns of Buruli Ulcer Incidence, Central Africa, 2002-2012.
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Mycobacterium ulcerans dynamics in aquatic ecosystems are driven by a complex interplay of abiotic and biotic factors.
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Development of a dry-reagent-based qPCR to facilitate the diagnosis of Mycobacterium ulcerans infection in endemic countries.
10.1371/journal.pntd.0003606
Extrahuman epidemiology of Acinetobacter baumannii in Lebanon.
10.1128/aem.03824-14
Mycobacterium ulcerans disease (Buruli ulcer) in Mali: A new potential African endemic country.
10.2340/00015555-1942
Buruli ulcer in South Western Nigeria: a retrospective cohort study of patients treated in Benin.
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[Detection of the IS2404 insertion sequence and ketoreductase produced by Mycobacterium ulcerans in the aquatic Heteroptera in the health districts of Dabou and Tiassalé in Côte d'Ivoire].
10.1684/mst.2014.0363
Topography and land cover of watersheds predicts the distribution of the environmental pathogen Mycobacterium ulcerans in aquatic insects.
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Buruli ulcer acquired in Mali: a rare and atypical situation.
10.1016/j.tmaid.2014.09.009
Findings in patients from Benin with osteomyelitis and polymerase chain reaction-confirmed Mycobacterium ulcerans infection.
10.1093/cid/ciu584
HIV infection and Buruli ulcer in Africa.
10.1016/s1473-3099(14)70882-5
Clinical epidemiology of laboratory-confirmed Buruli ulcer in Benin: a cohort study.
10.1016/s2214-109x(14)70223-2
Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.
10.1016/j.cell.2014.04.040
A case of guilt by association: Water bug bite incriminated in M. ulcerans infection.
10.1016/j.ijmyco.2014.01.004
Buruli ulcer disease in Republic of the Congo.
10.3201/eid2006.131498
Mycobacterium ulcerans ecological dynamics and its association with freshwater ecosystems and aquatic communities: results from a 12-month environmental survey in Cameroon.
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First detection of Mycobacterium ulcerans DNA in environmental samples from South America.
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[Buruli ulcer: a dynamic transversal research model performed through the international network of Pasteur Institutes].
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Photodegradation of the Mycobacterium ulcerans toxin, mycolactones: considerations for handling and storage.
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Adequate wound care and use of bed nets as protective factors against Buruli Ulcer: results from a case control study in Cameroon.
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Oral treatment for Mycobacterium ulcerans infection: results from a pilot study in Benin.
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Serological evaluation of Mycobacterium ulcerans antigens identified by comparative genomics.
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Use of fine-needle aspiration for diagnosis of Mycobacterium ulcerans infection.
10.1128/jcm.00558-10
Buruli ulcer, Central African Republic.
10.3201/eid1604.090195
Mycolactone gene expression is controlled by strong SigA-like promoters with utility in studies of Mycobacterium ulcerans and buruli ulcer.
10.1371/journal.pntd.0000553
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors.
10.1371/journal.ppat.1000645
Buruli ulcer in long-term traveler to Senegal.
10.3201/eid1501.080123
Optimized method for preparation of DNA from pathogenic and environmental mycobacteria.
10.1128/aem.01358-08
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
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Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis.
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Risk factors for buruli ulcer: a case control study in Cameroon.
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Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis.
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Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva.
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Early trafficking events of Mycobacterium ulcerans within Naucoris cimicoides.
10.1111/j.1462-5822.2006.00790.x
Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence.
10.1128/jb.00631-06
Immunogenicity of Mycobacterium ulcerans Hsp65 and protective efficacy of a Mycobacterium leprae Hsp65-based DNA vaccine against Buruli ulcer.
10.1016/j.micinf.2006.03.009
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence.
10.1128/iai.74.1.88-98.2006
Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin.
10.1111/j.1462-5822.2005.00546.x
Colonization of the salivary glands of Naucoris cimicoides by Mycobacterium ulcerans requires host plasmatocytes and a macrolide toxin, mycolactone.
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[Diagnosis of Mycobacterium ulcerans infections in French Guiana].
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Aquatic snails, passive hosts of Mycobacterium ulcerans.
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Aquatic plants stimulate the growth of and biofilm formation by Mycobacterium ulcerans in axenic culture and harbor these bacteria in the environment.
10.1128/aem.70.2.1097-1103.2004
Susceptibility of Mycobacterium ulcerans to a combination of amikacin/rifampicin.
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[Ecology and transmission of Mycobacterium ulcerans].
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Isolation of three Mycobacterium ulcerans strains resistant to rifampin after experimental chemotherapy of mice.
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Aquatic insects as a vector for Mycobacterium ulcerans.
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