Paperbase

Ricardo Lleonart

Lleonart Ricardo

ORCID: 0000-0002-5830-6315

Two initial vaccinations with the Bm86-based Gavacplus vaccine against Rhipicephalus (Boophilus) microplusinduce similar reproductive suppression to three initial vaccinations under production conditions 10.1186/1746-6148-6-43

Genome-wide discovery and development of polymorphic microsatellites from Leishmania panamensis parasites circulating in central Panama 10.1186/s13071-015-1153-2

Genetic structure of the contemporary Cuban population for nine STR loci 10.1016/S0531-5131(02)00841-5

Progress in the Identification of Dengue Virus Entry/Fusion Inhibitors 10.1155/2014/825039

Production of active anti-CD6 mouse/human chimeric antibodies in the milk of transgenic mice 10.1016/1380-2933(95)00010-0

The genome of Leishmania panamensis: Insights into genomics of the L. (Viannia) subgenus. 10.1038/srep08550

A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages 10.1371/journal.pone.0084107

High level expression of the B. microplus Bm86 antigen in the yeast Pichia pastoris forming highly immunogenic particles for cattle 10.1016/0168-1656(94)90106-6

AFLP Polymorphisms Allow High Resolution Genetic Analysis of American Tegumentary Leishmaniasis Agents Circulating in Panama and Other Members of the Leishmania Genus 10.1371/journal.pone.0073177

Control of Boophilus microplus populations in grazing cattle vaccinated with a recombinant Bm86 antigen preparation 10.1016/0304-4017(94)00678-6

Field studies and cost-effectiveness analysis of vaccination with Gavac(TM) against the cattle tick Boophilus microplus 10.1016/S0264-410X(97)00208-9

Detection of Bm86 antigen in different strains of Boophilus microplus and effectiveness of immunization with recombinant Bm86 10.1111/j.1365-3024.1994.tb00377.x

Production and biochemical characterization of the recombinant Boophilus microplus Bm95 antigen from Pichia pastoris 10.1023/B:APPA.0000018199.87122.e4

Differential constitutive expression of interferon genes in early mouse embryos 10.1002/mrd.1080410206

Vaccination against ticks (Boophilus spp.): The experience with the Bm86-based vaccine Gavac((TM)) 10.1016/S1050-3862(99)00018-2

High-level expression and immunogenic properties of the recombinant rabbit hemorrhagic disease virus VP60 capsid protein obtained in Pichia pastoris 10.1016/j.jbiotec.2005.01.013

Transgenic rabbits as bioreactors for the production of human growth hormone 10.1016/0168-1656(95)00026-M

Biochemical and structural characterization of RHDV capsid protein variants produced in Pichia pastoris: Advantages for immunization strategies and vaccine implementation 10.1016/j.antiviral.2008.08.007

A novel, quantitative bioassay for type i interferon using a recombinant indicator cell line 10.1038/nbt1290-1263

The recombinant rabbit hemorrhagic disease virus VP60 protein obtained from Pichia pastoris induces a strong humoral and cell-mediated immune response following intranasal immunization in mice 10.1016/j.vetmic.2005.11.062

Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles 10.1039/c6ob01149g

Genetic structure of a Cuban population based on nine short tandem repeat loci 10.1007/s00414-005-0522-3

Molecular cloning of the gene, expression in E. coli and purification of the thermus aquaticus DNA polymerase I 10.1002/abio.370120215

Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease 10.1021/acschemneuro.6b00386

Simulation of control strategies for the cattle tick Boophilus microplus employing vaccination with a recombinant Bm86 antigen preparation 10.1016/0304-4017(95)00855-1

Molecular and antigenic characterization of rabbit hemorrhagic disease virus isolated in Cuba indicates a distinct antigenic subtype 10.1007/s00705-006-0926-5

Phage-Displayed Peptides Selected to Bind Envelope Glycoprotein Show Antiviral Activity against Dengue Virus Serotype 2 10.1155/2017/1827341

Use of AFLP for the study of eukaryotic pathogens affecting humans 10.1016/j.meegid.2017.09.017

Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2 10.3390/molecules23030672

VianniaTopes: a database of predicted immunogenic peptides for Leishmania (Viannia) species 10.1093/database/bay111

Transient transformation of shrimp (Penaeus schmitti) embryos by DNA microinjection 10.1016/0093-691x(95)92334-6

Hexahydropyrrolo[2,3-b]indole compounds as potential therapeutics for Alzheimer Disease. 10.1021/acschemneuro.9b00297

Forensic identification of skeletal remains from members of Ernesto Che Guevara's guerrillas in Bolivia based on DNA typing. 10.1007/pl00007716

Yisett González

González Yisett

ORCID: 0000-0002-1623-9484

A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS 10.3390/biom8040109

A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages 10.1371/journal.pone.0084107

Marine Diterpenoids as Potential Anti-Inflammatory Agents 10.1155/2015/263543

Uprolides N, O and P from the Panamanian octocoral Eunicea succinea 10.3390/molecules21060819

Flavonoids from Boldoa purpurascens inhibit proinflammatory cytokines (TNF-α and IL-6) and the expression of COX-2 10.1002/ptr.6104

seco-briarellinone and briarellin S, two new eunicellin-based diterpenoids from the panamanian octocoral Briareum asbestinum 10.3390/md10112608

Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer's Disease 10.3233/JAD-170071

Patricia Llanes Fernandez

Llanes Fernandez Patricia

ORCID: 0000-0002-0762-0566

Hemolysis-induced lethality involves inflammasome activation by heme. 10.1073/pnas.1405023111

Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis. 10.1186/1742-2094-11-48

A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages. 10.1371/journal.pone.0084107

AFLP polymorphisms allow high resolution genetic analysis of American Tegumentary Leishmaniasis agents circulating in Panama and other members of the Leishmania genus. 10.1371/journal.pone.0073177

Potential immunotargets for Alzheimer's disease treatment strategies. 10.3233/JAD-2012-121222

seco-Briarellinone and briarellin S, two new eunicellin-based diterpenoids from the Panamanian octocoral Briareum asbestinum. 10.3390/md10112608

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production. 10.1182/blood-2011-08-375303

TLR4 recognizes Pseudallescheria boydii conidia and purified rhamnomannans. 10.1074/jbc.M110.181255

Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation. 10.1074/jbc.M110.146076

Heme induces neutrophil migration and reactive oxygen species generation through signaling pathways characteristic of chemotactic receptors. 10.1074/jbc.M703570200

Characterization of heme as activator of Toll-like receptor 4. 10.1074/jbc.M610737200

An alpha-glucan of Pseudallescheria boydii is involved in fungal phagocytosis and Toll-like receptor activation. 10.1074/jbc.M511417200

Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea 10.3390/molecules21060819

Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles. 10.1039/c6ob01149g

Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer’s drug discovery 10.2147/CIA.S134605

Both B-1a and B-1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody-secreting cells. 10.1111/imm.12909

Total IgM and Anti-Phosphatidylcholine IgM Antibody Secretion Continue After Clearance of Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection. 10.1007/s00408-017-0019-0

Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer's Disease. 10.3233/jad-170071

Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease. 10.1021/acschemneuro.6b00386

Marine Diterpenoids as Potential Anti-Inflammatory Agents. 10.1155/2015/263543

A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS 10.3390/biom8040109

Hexahydropyrrolo[2,3-b]indole Compounds as Potential Therapeutics for Alzheimer’s Disease 10.1021/acschemneuro.9b00297

Marcelino Gutierrez

Gutierrez Marcelino

ORCID: 0000-0003-1423-3772

Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea 10.3390/molecules21060819

Imaging mass spectrometry and MS/MS molecular networking reveals chemical interactions among cuticular bacteria and pathogenic fungi associated with fungus-growing ants 10.1038/s41598-017-05515-6

Antimicrobial‐producing Pseudoalteromonas from the marine environment of Panama shows a high phylogenetic diversity and clonal structure 10.1002/jobm.201800087

Imaging Mass Spectrometry of a Coral Microbe Interaction with Fungi 10.1007/s10886-013-0320-1

Leptolide, a new furanocembranolide diterpene from Leptogorgia alba 10.1021/np049745z

Cannabinomimetic lipid from a marine cyanobacterium 10.1021/np200610t

Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula 10.1021/jo900578j

Antiprotozoal activity against Plasmodium falciparum and Trypanosoma cruzi of aeroplysinin-1 isolated from the new sponge Aplysina chiriquensis 10.1080/13880200500406503

Antiplasmodial activity of bacilosarcin A isolated from the octocoral-associated bacterium Bacillus sp. collected in Panama 10.4103/0975-7406.92739

Antitrypanosomal alkaloids from the marine bacterium Bacillus pumilus 10.3390/molecules170911146

L-Galactose as a natural product: Isolation from a marine octocoral of the first α-L-galactosyl saponin 10.1016/j.tetlet.2004.08.170

MS/MS networking guided analysis of molecule and gene cluster families 10.1073/pnas.1303471110

Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new Guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida 10.1021/np800121a

seco-briarellinone and briarellin S, two new eunicellin-based diterpenoids from the panamanian octocoral Briareum asbestinum 10.3390/md10112608

Dudawalamides A-D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens 10.1021/acs.jnatprod.7b00034

Antiplasmodial metabolites isolated from the marine octocoral Muricea austera 10.1021/np060007f

A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages 10.1371/journal.pone.0084107

Microbiota of healthy corals are active against fungi in a light-dependent manner 10.1021/cb500432j

Toxins and pharmacologically active compounds from species of the family Bufonidae (Amphibia, Anura) 10.1016/j.jep.2016.12.021

Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides 10.1021/ac900114t

Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium lyngbya majuscula 10.1021/np9005184

Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer's Disease 10.3233/JAD-170071

Pumilacidins from the Octocoral-Associated Bacillus sp. DT001 Display Anti-Proliferative Effects in Plasmodium falciparum 10.3390/molecules23092179

A Marine Diterpenoid Modulates the Proteasome Activity in Murine Macrophages Stimulated with LPS 10.3390/biom8040109

Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and molecular networking 10.1038/s41598-019-39583-7

Antiparasitic Compounds from the Panamanian Marine Bacterium Pseudomonas aeruginosa https://doi.org/10.1177/1934578X1901400109

Fungus-Growing Ant’s Microbial Interaction of Streptomyces sp. and Escovopsis sp. through Molecular Networking and MALDI Imaging https://doi.org/10.1177/1934578X1901400117

New Eunicellin-Type Diterpenes from the Panamanian Octocoral Briareum asbestinum 10.3390/md18020084

Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién 10.1371/journal.pone.0214193

19-Hydroxy-bufalin, a major bufadienolide isolated from the parotoid gland secretions of the Panamanian endemic toad Rhinella centralis (Bufonidae), inhibits the growth of Trypanosoma cruzi 10.1016/j.toxicon.2020.02.009

Reproducible molecular networking of untargeted mass spectrometry data using GNPS 10.1038/s41596-020-0317-5

Genome Mining, Microbial Interactions, and Molecular Networking Reveals New Dibromoalterochromides from Strains of Pseudoalteromonas of Coiba National Park-Panama 10.3390/md18090456

Metabolites from Microbes Isolated from the Skin of the Panamanian Rocket Frog Colostethus panamansis (Anura: Dendrobatidae) 10.3390/metabo10100406

Antimicrobial Secretions of Toads (Anura, Bufonidae): Bioactive Extracts and Isolated Compounds against Human Pathogens 10.3390/antibiotics9120843

Antibacterial Activity of Volatile Organic Compounds Produced by the Octocoral-Associated Bacteria Bacillus sp. BO53 and Pseudoalteromonas sp. GA327 10.3390/antibiotics9120923

Bufadienolides from the Skin Secretions of the Neotropical Toad Rhinella alata (Anura: Bufonidae): Antiprotozoal Activity against Trypanosoma cruzi 10.3390/molecules26144217