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Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis

Ribeiro, Ana Luisa de Jesus Lopes Degiacomi, Giulia Ewann, Fanny Buroni, Silvia Incandela, Maria Loreto Chiarelli, Laurent R. Mori, Giorgia Kim, Jaeseung Contreras-Dominguez, Monica Park, Young-Sam Han, Sung-Jun Brodin, Priscille Valentini, Giovanna Rizzi, Menico Riccardi, Giovanna Pasca, Maria Rosalia

Plos One, 2011

https://doi.org/10.1371/journal.pone.0026675

Giovanna RICCARDI

RICCARDI Giovanna

ORCID: 0000-0003-3295-0070

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Sequence of the Bacillus stearothermophilus gene encoding aspartokinase II 10.1016/0378-1119(95)00834-9

Antituberculars which target decaprenylphosphoryl-β-Dribofuranose 2′-oxidase DprE1: State of art 10.1007/s00253-012-4013-4

Gene arrangement and organization in a ~ 76 kb fragment: Encompassing the oriC region of the chromosome of Mycobacterium leprae 10.1099/13500872-142-11-3147

Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a functional origin from M. smegmatis 10.1111/j.1365-2958.1996.tb02617.x

Detection and characterization of naturally occurring plasmids in Bacillus licheniformis 10.1111/j.1574-6968.1991.tb04781.x

Molecular mechanisms of chlorhexidine tolerance in Burkholderia cenocepacia biofilms 10.1128/AAC.01571-10

Differential roles of rnd efflux pumps in antimicrobial drug resistance of sessile and planktonic burkholderia cenocepacia cells 10.1128/AAC.03800-14

Erratum: Antituberculars which target decaprenylphosphoryl-β-D- ribofuranose 2'-oxidase DprE1: State of art (Applied Microbiology and Biotechnology (2012) 94 (907-916) DOI: 10.1007/s00253-012-4013-4) 10.1007/s00253-012-4217-7

Antibiotic resistance of benthic bacteria in fish-farm and control sediments of the Western Mediterranean 10.1016/S0044-8486(03)00016-4

Amino acid biosynthesis and its regulation in cyanobacteria 10.1016/0168-9452(89)90018-6

Characterization of Gram-positive broad host-range plasmids carrying a thermophilic replicon 10.1016/0923-2508(91)90108-M

4-Aminoquinolone piperidine amides: Noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity 10.1021/jm5005978

Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa multidrug resistance clinical isolates 10.1089/mdr.2011.0019

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Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 10.1186/1471-2180-9-200

Erratum: Global analysis of the Mycobacterium tuberculosis zur (FurB) regulon (Journal of Bacteriology (2007) 189, 3, (730-740)) 10.1128/JB.00593-07

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Role of mycobacterial efflux transporters in drug resistance: An unresolved question 10.1111/j.1574-6976.2005.00002.x

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Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 10.1111/j.1574-6968.2008.01320.x

Mechanism of resistance to an antitubercular 2-thiopyridine derivative that is also active against Burkholderia cenocepacia 10.1128/AAC.02438-13

Determination of a 15437 bp nucleotide sequence around the inhA gene of Mycobacterium avium and similarity analysis of the products of putative ORFs 10.1099/00221287-144-3-807

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Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis 10.1126/scitranslmed.3004395

Biochemical characterization of glutamate Racemase - A new candidate drug target against Burkholderia cenocepacia infections 10.1371/journal.pone.0167350

Cloning and sequencing of the ilvBNC gene cluster from Mycobacterium avium 10.1016/0378-1119(96)00275-2

Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis 10.1021/cb500149m

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 10.1016/j.tube.2008.08.003

Molecular cloning and expression of Spirulina platensis acetohydroxy acid synthase genes in Escherichia coli 10.1007/BF00243456

Development of a repressible mycobacterial promoter system based on two transcriptional repressors 10.1093/nar/gkq235

Characterisation and antimicrobial activity of epibiotic bacteria from Petrosia ficiformis (Porifera, Demospongiae) 10.1016/j.jembe.2004.03.006

Genetic transformation of intact cells of Bacillus subtilis by electroporation 10.1016/0378-1097(90)90182-P

Transcriptional regulation of furA and katG upon oxidative stress in Mycobacterium smegmatis 10.1128/JB.183.23.6801-6806.2001

Mechanism of action of 5-nitrothiophenes against mycobacterium tuberculosis 10.1128/AAC.02693-13

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis 10.1007/s00253-013-5218-x

Burkholderia cenocepacia infections in cystic fibrosis patients: Drug resistance and therapeutic approaches 10.3389/fmicb.2017.01592

Structural organization of pBC1, a cryptic plasmid from Bacillus coagulans 10.1128/jb.174.2.638-642.1992

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Bacterial community structure and activity in fish farm sediments of the Ligurian Sea (Western Mediterranean) 10.1023/A:1021365829687

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The Crystal Structure of Burkholderia cenocepacia DfsA Provides Insights into Substrate Recognition and Quorum Sensing Fatty Acid Biosynthesis 10.1021/acs.biochem.6b00178

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A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors 10.1021/acsinfecdis.7b00006

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Exploring the HME and HAE1 efflux systems in the genus Burkholderia 10.1186/1471-2148-10-164

Plasmid screening in thermophilic Bacillus: Physical characterization and molecular cloning 10.1007/BF01568897

The Mycobacterium tuberculosis Rv2358-furB operon is induced by zinc 10.1016/j.resmic.2003.11.009

New prodrugs against tuberculosis 10.1016/j.drudis.2016.09.006

Decaprenylphosphoryl-β-D-ribose 2'-epimerase from Mycobacterium tuberculosis is a magic drug target 10.2174/092986710791959693

Molecular cloning and sequencing of the β-isopropylmalate dehydrogenase gene from the cyanobacterium Spirulina platensis 10.1099/00221287-138-3-493

Cloning of the glutamine synthetase gene from spirulina platensis 10.1007/BF02418760

Characterization of a mutant of chlamydomonas reinhardtII resistant to fusidic acid 10.1016/0014-5793(81)81166-0

Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo 10.1038/srep32487

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Competitive fitness of essential gene knockdowns reveals a broad-spectrum antibacterial inhibitor of the cell division protein FtsZ 10.1128/AAC.01231-18

A census of RND superfamily proteins in the Burkholderia genus 10.2217/fmb.13.50

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Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 10.1128/JB.01190-06

Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: Biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis 10.1371/journal.pone.0015494

New tuberculosis drugs on the horizon 10.1016/j.mib.2011.07.022

A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 10.1038/s41598-018-21614-4

Rv2358 and FurB: Two transcriptional regulators from Mycobacterium tuberculosis which respond to zinc 10.1128/JB.187.16.5837-5840.2005

Mycobacterium tuberculosis H37Rv comparative gene-expression analysis in synthetic medium and human macrophage 10.1016/S0378-1119(00)00249-3

In vitro translation of chloroplast mRNAs 10.1016/0304-4211(82)90148-1

High content screening identifies decaprenyl-phosphoribose 2′ epimerase as a target for intracellular antimycobacterial inhibitors 10.1371/journal.ppat.1000645

The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053 10.1074/jbc.M115.677039

Biofilm-Grown Burkholderia cepacia Complex Cells Survive Antibiotic Treatment by Avoiding Production of Reactive Oxygen Species 10.1371/journal.pone.0058943

Identification and characterization of a new ligand-binding site in FnbB, a fibronectin-binding adhesin from Streptococcus dysgalactiae 10.1016/S1570-9639(03)00020-7

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 10.1371/journal.pone.0026675

Erratum: Rv2358 and FurB: Two transcriptional regulators from Mycobacterium tuberculosis which respond to zinc (Journal of Bacteriology (2005) 187, 16 (5837-5840)) 10.1128/JB.00141-07

Glutamine amidotransferase activity of NAD⁺ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain 10.1016/j.resmic.2004.08.011

Techniques and Applications: The heterologous expression of Mycobacterium tuberculosis genes is an uphill road 10.1016/S0966-842X(03)00180-X

Characterization of mutants of Spirulina platensis resistant to amino acid analogues 10.1111/j.1574-6968.1981.tb07668.x

The TB structural genomics consortium: A resource for Mycobacterium tuberculosis biology 10.1016/S1472-9792(03)00051-9

Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones 10.1128/AAC.01676-09

New shuttle vector for cloning in Bacillus stearothermophilus 10.1016/0923-2508(94)90074-4

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Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator 10.1128/JB.00631-09

Trends in discovery of new drugs for tuberculosis therapy 10.1038/ja.2014.109

DprE1, a new taxonomic marker in mycobacteria 10.1111/1574-6968.12246

Efflux-mediated resistance to a benzothiadiazol derivative effective against Burkholderia cenocepacia 10.3389/fmicb.2015.00815

mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 10.1128/AAC.49.11.4775-4777.2005

Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis 10.1128/AAC.48.8.3175-3178.2004

Contribution of the multidrug efflux pump LfrA to innate mycobacterial drug resistance 10.1016/S0378-1097(00)00456-0

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Mycobacterium tuberculosis fura autoregulates its own expression 10.1128/JB.185.18.5357-5362.2003

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Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-d-ribofuranose 2′-oxidase DprE1 10.1021/ja211042r

New Insights into the Mechanism of Action of the Thienopyrimidine Antitubercular Prodrug TP053 10.1021/acsinfecdis.9b00388

2-carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1 10.1021/cb5007163

The katE gene, which encodes the catalase HPII of Mycobacterium avium 10.1046/j.1365-2958.1996.352876.x

Sequence of the gene encoding an alkaline serine protease of thermophilic Bacillus smithii 10.1016/0378-1119(94)90340-9

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Silvia Buroni

Buroni Silvia

ORCID: 0000-0002-6979-2275

Email: silvia.buroni@unipv.it