20S proteasome as a drug target in Trichomonas vaginalis
O'Donoghue, Anthony J.
Bibo-Verdugo, Betsaida
Miyamoto, Yukiko
Wang, Steven C.
Yang, Justin Z.
Zuill, Douglas E.
Matsuka, Shoun
Jiang, Zhenze
Almaliti, Jehad
Caffrey, Conor R.
Gerwick, William H.
Eckmann, Lars
Anthony O'Donoghue
O'Donoghue Anthony
ORCID: 0000-0001-5695-0409
Validation of Babesia proteasome as a drug target
10.1016/j.ijpddr.2018.08.001
A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro
10.1021/acschembio.8b00420
Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology
10.1021/acs.jmedchem.8b01536
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry
10.1074/mcp.TIR118.001099
20S Proteasome as a Drug Target in Trichomonas vaginalis
10.1128/AAC.00448-19
Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant
10.1021/acsomega.9b02491
Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses
10.1074/mcp.RA120.002079
High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma
10.3390/molecules25184071
A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding
10.1126/science.abb7709
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity
10.1021/acssensors.1c00518
Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing
10.1021/acschemneuro.1c00133
Zhenze Jiang
Jiang Zhenze
ORCID: 0000-0001-9570-1739
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry
10.1074/mcp.TIR118.001099
The Pseudomonas aeruginosa protease LasB directly activates IL-1 beta
10.1016/J.EBIOM.2020.102984
High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma
10.3390/MOLECULES25184071
Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses
10.1074/MCP.RA120.002079
Engineering of multiple trypsin/chymotrypsin sites in Cry3A to enhance its activity against Monochamus alternatus Hope larvae
10.1002/PS.5866
20S Proteasome as a Drug Target in Trichomonas vaginalis
10.1128/AAC.00448-19
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni
10.1021/ACSINFECDIS.9B00237
Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome
10.1515/HSZ-2018-0240
An internally quenched peptide as a new model substrate for rhomboid intramembrane proteases
10.1515/HSZ-2018-0255
A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro
10.1021/ACSCHEMBIO.8B00420
Skin Commensal Malassezia globosa Secreted Protease Attenuates Staphylococcus aureus Biofilm Formation
10.1016/J.JID.2017.11.034
Targeting proteasomes in infectious organisms to combat disease
10.1111/FEBS.14029
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties
10.1371/JOURNAL.PNTD.0006446
An enzyme-free signal amplification strategy for sensitive detection of microRNA via catalyzed hairpin assembly
10.1039/C4AY02142H
Insights into the catalytic properties of the mitochondrial rhomboid protease PARL
10.1016/J.JBC.2021.100383
Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing
10.1021/acschemneuro.1c00133
Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions
10.1021/acschembio.1c00138
jehad almaliti
almaliti jehad
ORCID: 0000-0002-3562-0846
Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel
10.1016/j.chembiol.2016.04.008
Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria
10.1021/acs.jnatprod.5b00301
Natural products inspired synthesis of neuroprotective agents against H2O2-induced cell death
10.1016/j.bmcl.2013.01.013
Dudawalamides A–D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens
10.1021/acs.jnatprod.7b00034
Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species
10.1021/acs.jnatprod.7b00367
20S proteasome as a drug target in Trichomonas vaginalis
10.1128/AAC.00448-19
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages
10.1016/j.foodchem.2019.125290
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity
10.1021/acs.jmedchem.7b00671
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni
10.1021/acsinfecdis.9b00237
Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents
10.1016/j.ejmech.2018.10.024
Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain
10.1021/acs.jmedchem.9b00294
Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue
10.1021/acs.jmedchem.6b01271
