Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption
Cara C. Rada
Hilda Mejia-Pena
Neil J. Grimsey
Isabel Canto Cordova
Joshua Olson
Jacob M. Wozniak
David J. Gonzalez
Victor Nizet
JoAnn Trejo
Science Signaling, 2021-8-31
Jacob Wozniak
Wozniak Jacob
ORCID: 0000-0002-2453-0861
Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function
10.1073/pnas.1917295117
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
10.1016/j.cell.2017.12.032
American Gut: an Open Platform for Citizen Science Microbiome Research
10.1128/msystems.00031-18
Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Protein Vpr
10.1074/mcp.m116.066019
Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas
10.1016/j.cels.2018.04.010
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages
10.1016/j.foodchem.2019.125290
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry
10.1074/mcp.tir118.001099
Optimization of carbon and energy utilization through differential translational efficiency
10.1038/s41467-018-06993-6
EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells
10.1038/s41556-019-0330-5
Organ-level protein networks as a reference for the host effects of the microbiome
10.1101/gr.256875.119
Quantitative analysis of Mycobacterium avium subsp. hominissuis proteome in response to antibiotics and during exposure to different environmental conditions
10.1186/s12014-019-9260-2
AssessORF: combining evolutionary conservation and proteomics to assess prokaryotic gene predictions
10.1093/bioinformatics/btz714
PTMphinder: an R package for PTM site localization and motif extraction from proteomic datasets
10.7717/peerj.7046
Functional and Proteomic Analysis of Streptococcus pyogenes Virulence Upon Loss of Its Native Cas9 Nuclease
10.3389/fmicb.2019.01967
Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways
10.1371/journal.pntd.0007980
Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures
10.1016/j.cell.2020.07.040
CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly
10.1073/pnas.2018251118
Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption
10.1126/scisignal.abc1044
Neil Grimsey
Grimsey Neil
ORCID: 0000-0002-0481-4920
The unfolded protein response regulator ATF6 promotes mesodermal differentiation
10.1126/scisignal.aan5785
The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation.
10.2337/db08-0184
Two human ARFGAPs associated with COP-I-coated vesicles.
10.1111/j.1600-0854.2007.00631.x
Control of phospholipid synthesis by phosphorylation of the yeast lipin Pah1p/Smp2p Mg2+-dependent phosphatidate phosphatase.
10.1074/jbc.M606654200
The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth.
10.1038/sj.emboj.7600672
A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling.
10.1016/j.celrep.2018.08.061
ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif.
10.1371/journal.pone.0157587
Integration of endothelial protease-activated receptor-1 inflammatory signaling by ubiquitin.
10.1097/MOH.0000000000000232
Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.
10.1074/jbc.M115.702993
Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes.
10.1083/jcb.201504007
A general method for site specific fluorescent labeling of recombinant chemokines.
10.1371/journal.pone.0081454
Endosomal signaling by protease-activated receptors.
10.1016/B978-0-12-397925-4.00022-5
Distinct roles of the phosphatidate phosphatases lipin 1 and 2 during adipogenesis and lipid droplet biogenesis in 3T3-L1 cells.
10.1074/jbc.M113.488445
Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals.
10.1074/jbc.M111.299776
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.
10.1172/jci46095
Regulation of protease-activated receptor signaling by post-translational modifications.
10.1002/iub.442
Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2.
10.1074/jbc.M804278200
Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations.
10.2337/db08-0422
G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2 and TAB1-TAB3 dependent pathway in endothelial cells
10.1074/jbc.ra119.007495
The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein–coupled receptor lysosomal sorting
10.1091/mbc.e15-05-0284
Ubiquitination as a Key Regulator of Endosomal Signaling by GPCRs.
10.3389/fcell.2019.00043
Atypical p38 Signaling, Activation, and Implications for Disease
10.3390/ijms22084183
Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption
10.1126/scisignal.abc1044