Paperbase

Giovanna RICCARDI

RICCARDI Giovanna

ORCID: 0000-0003-3295-0070

Mycobacterium tuberculosis: Drug resistance and future perspectives 10.2217/fmb.09.20

Sequence of the Bacillus stearothermophilus gene encoding aspartokinase II 10.1016/0378-1119(95)00834-9

Antituberculars which target decaprenylphosphoryl-β-Dribofuranose 2′-oxidase DprE1: State of art 10.1007/s00253-012-4013-4

Gene arrangement and organization in a ~ 76 kb fragment: Encompassing the oriC region of the chromosome of Mycobacterium leprae 10.1099/13500872-142-11-3147

Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a functional origin from M. smegmatis 10.1111/j.1365-2958.1996.tb02617.x

Detection and characterization of naturally occurring plasmids in Bacillus licheniformis 10.1111/j.1574-6968.1991.tb04781.x

Molecular mechanisms of chlorhexidine tolerance in Burkholderia cenocepacia biofilms 10.1128/AAC.01571-10

Differential roles of rnd efflux pumps in antimicrobial drug resistance of sessile and planktonic burkholderia cenocepacia cells 10.1128/AAC.03800-14

Erratum: Antituberculars which target decaprenylphosphoryl-β-D- ribofuranose 2'-oxidase DprE1: State of art (Applied Microbiology and Biotechnology (2012) 94 (907-916) DOI: 10.1007/s00253-012-4013-4) 10.1007/s00253-012-4217-7

Antibiotic resistance of benthic bacteria in fish-farm and control sediments of the Western Mediterranean 10.1016/S0044-8486(03)00016-4

Amino acid biosynthesis and its regulation in cyanobacteria 10.1016/0168-9452(89)90018-6

Characterization of Gram-positive broad host-range plasmids carrying a thermophilic replicon 10.1016/0923-2508(91)90108-M

4-Aminoquinolone piperidine amides: Noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity 10.1021/jm5005978

Evaluation of fluoroquinolone resistance mechanisms in Pseudomonas aeruginosa multidrug resistance clinical isolates 10.1089/mdr.2011.0019

Benzothiazinones Kill Mycobacterium tuberculosis by blocking Arabinan synthesis 10.1126/science.1171583

Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance 10.1186/1471-2180-9-200

Erratum: Global analysis of the Mycobacterium tuberculosis zur (FurB) regulon (Journal of Bacteriology (2007) 189, 3, (730-740)) 10.1128/JB.00593-07

Molecular characterization of the genes encoding acetohydroxy acid synthase in the cyanobacterium Spirulina platensis 10.1099/00221287-138-7-1399

Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome 10.1186/1471-2180-6-66

Role of mycobacterial efflux transporters in drug resistance: An unresolved question 10.1111/j.1574-6976.2005.00002.x

Phenotypic and Genotypic Characterisation of Burkholderia cenocepacia J2315 Mutants Affected in Homoserine Lactone and Diffusible Signal Factor-Based Quorum Sensing Systems Suggests Interplay between Both Types of Systems 10.1371/journal.pone.0055112

Molecular approaches to pathogenesis study of Burkholderia cenocepacia, an important cystic fibrosis opportunistic bacterium 10.1007/s00253-011-3616-5

Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD⁺ synthetase 10.1016/S1046-5928(02)00041-4

Transcriptional analysis of ESAT-6 cluster 3 in Mycobacterium smegmatis 10.1186/1471-2180-9-48

Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis 10.1111/j.1574-6968.2008.01320.x

Mechanism of resistance to an antitubercular 2-thiopyridine derivative that is also active against Burkholderia cenocepacia 10.1128/AAC.02438-13

Determination of a 15437 bp nucleotide sequence around the inhA gene of Mycobacterium avium and similarity analysis of the products of putative ORFs 10.1099/00221287-144-3-807

Biochemical evidence for multiple forms of acetohydroxy acid synthase in Spirulina platensis 10.1007/BF00252216

Investigating the mechanism of action of diketopiperazines inhibitors of the burkholderia cenocepacia quorum sensing synthase CepI: A site-directed mutagenesis study 10.3389/fphar.2018.00836

Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis 10.1126/scitranslmed.3004395

Biochemical characterization of glutamate Racemase - A new candidate drug target against Burkholderia cenocepacia infections 10.1371/journal.pone.0167350

Cloning and sequencing of the ilvBNC gene cluster from Mycobacterium avium 10.1016/0378-1119(96)00275-2

Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis 10.1021/cb500149m

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system 10.1016/j.tube.2008.08.003

Molecular cloning and expression of Spirulina platensis acetohydroxy acid synthase genes in Escherichia coli 10.1007/BF00243456

Development of a repressible mycobacterial promoter system based on two transcriptional repressors 10.1093/nar/gkq235

Characterisation and antimicrobial activity of epibiotic bacteria from Petrosia ficiformis (Porifera, Demospongiae) 10.1016/j.jembe.2004.03.006

Genetic transformation of intact cells of Bacillus subtilis by electroporation 10.1016/0378-1097(90)90182-P

Transcriptional regulation of furA and katG upon oxidative stress in Mycobacterium smegmatis 10.1128/JB.183.23.6801-6806.2001

Mechanism of action of 5-nitrothiophenes against mycobacterium tuberculosis 10.1128/AAC.02693-13

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis 10.1007/s00253-013-5218-x

Burkholderia cenocepacia infections in cystic fibrosis patients: Drug resistance and therapeutic approaches 10.3389/fmicb.2017.01592

Structural organization of pBC1, a cryptic plasmid from Bacillus coagulans 10.1128/jb.174.2.638-642.1992

Vaccines to Overcome Antibiotic Resistance: The Challenge of Burkholderia cenocepacia 10.1016/j.tim.2019.12.005

Raising awareness of the importance of funding for tuberculosis small-molecule research 10.1016/j.drudis.2016.09.012

Bacterial community structure and activity in fish farm sediments of the Ligurian Sea (Western Mediterranean) 10.1023/A:1021365829687

Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance 10.1111/j.1365-2958.2010.07277.x

The Crystal Structure of Burkholderia cenocepacia DfsA Provides Insights into Substrate Recognition and Quorum Sensing Fatty Acid Biosynthesis 10.1021/acs.biochem.6b00178

The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens 10.1016/j.ejmech.2020.112132

A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors 10.1021/acsinfecdis.7b00006

Deciphering the role of rnd efflux transporters in burkholderia cenocepacia 10.1371/journal.pone.0018902

Exploring the HME and HAE1 efflux systems in the genus Burkholderia 10.1186/1471-2148-10-164

Plasmid screening in thermophilic Bacillus: Physical characterization and molecular cloning 10.1007/BF01568897

The Mycobacterium tuberculosis Rv2358-furB operon is induced by zinc 10.1016/j.resmic.2003.11.009

New prodrugs against tuberculosis 10.1016/j.drudis.2016.09.006

Decaprenylphosphoryl-β-D-ribose 2'-epimerase from Mycobacterium tuberculosis is a magic drug target 10.2174/092986710791959693

Molecular cloning and sequencing of the β-isopropylmalate dehydrogenase gene from the cyanobacterium Spirulina platensis 10.1099/00221287-138-3-493

Cloning of the glutamine synthetase gene from spirulina platensis 10.1007/BF02418760

Characterization of a mutant of chlamydomonas reinhardtII resistant to fusidic acid 10.1016/0014-5793(81)81166-0

Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo 10.1038/srep32487

A highly efficient electroporation system for transformation of Bacillus licheniformis 10.1007/BF00152745

Competitive fitness of essential gene knockdowns reveals a broad-spectrum antibacterial inhibitor of the cell division protein FtsZ 10.1128/AAC.01231-18

A census of RND superfamily proteins in the Burkholderia genus 10.2217/fmb.13.50

LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis 10.1128/AAC.00656-06

Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon 10.1128/JB.01190-06

Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: Biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis 10.1371/journal.pone.0015494

New tuberculosis drugs on the horizon 10.1016/j.mib.2011.07.022

A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 10.1038/s41598-018-21614-4

Rv2358 and FurB: Two transcriptional regulators from Mycobacterium tuberculosis which respond to zinc 10.1128/JB.187.16.5837-5840.2005

Mycobacterium tuberculosis H37Rv comparative gene-expression analysis in synthetic medium and human macrophage 10.1016/S0378-1119(00)00249-3

In vitro translation of chloroplast mRNAs 10.1016/0304-4211(82)90148-1

High content screening identifies decaprenyl-phosphoribose 2′ epimerase as a target for intracellular antimycobacterial inhibitors 10.1371/journal.ppat.1000645

The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053 10.1074/jbc.M115.677039

Biofilm-Grown Burkholderia cepacia Complex Cells Survive Antibiotic Treatment by Avoiding Production of Reactive Oxygen Species 10.1371/journal.pone.0058943

Identification and characterization of a new ligand-binding site in FnbB, a fibronectin-binding adhesin from Streptococcus dysgalactiae 10.1016/S1570-9639(03)00020-7

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 10.1371/journal.pone.0026675

Erratum: Rv2358 and FurB: Two transcriptional regulators from Mycobacterium tuberculosis which respond to zinc (Journal of Bacteriology (2005) 187, 16 (5837-5840)) 10.1128/JB.00141-07

Glutamine amidotransferase activity of NAD⁺ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain 10.1016/j.resmic.2004.08.011

Techniques and Applications: The heterologous expression of Mycobacterium tuberculosis genes is an uphill road 10.1016/S0966-842X(03)00180-X

Characterization of mutants of Spirulina platensis resistant to amino acid analogues 10.1111/j.1574-6968.1981.tb07668.x

The TB structural genomics consortium: A resource for Mycobacterium tuberculosis biology 10.1016/S1472-9792(03)00051-9

Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones 10.1128/AAC.01676-09

New shuttle vector for cloning in Bacillus stearothermophilus 10.1016/0923-2508(94)90074-4

Biochemical characterization and cloning of acetohydroxy acid synthase from spirulina platensis 10.1080/11263509009430656

Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator 10.1128/JB.00631-09

Trends in discovery of new drugs for tuberculosis therapy 10.1038/ja.2014.109

DprE1, a new taxonomic marker in mycobacteria 10.1111/1574-6968.12246

Efflux-mediated resistance to a benzothiadiazol derivative effective against Burkholderia cenocepacia 10.3389/fmicb.2015.00815

mmpL7 gene of Mycobacterium tuberculosis is responsible for isoniazid efflux in Mycobacterium smegmatis 10.1128/AAC.49.11.4775-4777.2005

Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis 10.1128/AAC.48.8.3175-3178.2004

Contribution of the multidrug efflux pump LfrA to innate mycobacterial drug resistance 10.1016/S0378-1097(00)00456-0

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG 10.1016/j.chembiol.2015.05.016

Mycobacterium tuberculosis fura autoregulates its own expression 10.1128/JB.185.18.5357-5362.2003

PEGylated mucus-penetrating nanocrystals for lung delivery of a new FtsZ inhibitor against Burkholderia cenocepacia infection 10.1016/j.nano.2019.102113

Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-d-ribofuranose 2′-oxidase DprE1 10.1021/ja211042r

New Insights into the Mechanism of Action of the Thienopyrimidine Antitubercular Prodrug TP053 10.1021/acsinfecdis.9b00388

2-carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1 10.1021/cb5007163

The katE gene, which encodes the catalase HPII of Mycobacterium avium 10.1046/j.1365-2958.1996.352876.x

Sequence of the gene encoding an alkaline serine protease of thermophilic Bacillus smithii 10.1016/0378-1119(94)90340-9

Cloning, sequencing and expression of the ilvBNC gene cluster from Streptomyces avermitilis 10.1016/0378-1119(95)00563-4

Philip Butcher

Butcher Philip

ORCID: 0000-0003-1223-9097

Intracellular Microbe Whole-Genome Expression Profiling: Methodological Considerations and Biological Inferences 10.1002/9783527629176.ch9

Investigation of mycobacteria in Crohn's disease tissue by Southern blotting and DNA hybridisation with cloned mycobacterial genomic DNA probes from a Crohn's disease isolated mycobacteria 10.1136/gut.29.9.1222

Fidelity and reproducibility of antisense RNA amplification for the study of gene expression in human CD34 ⁺ haemopoietic stem and progenitor cells 10.1046/j.1365-2141.2003.04440.x

Analysis of whole-genome microarray replicates using mixed models 10.1093/bioinformatics/19.1.53

Evidence for a role for interleukin-17, Th17 cells and iron homeostasis in protective immunity against tuberculosis in cynomolgus macaques 10.1371/journal.pone.0088149

Inactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37Rv 10.1111/j.1472-765X.2005.01659.x

Use of Genome Level-Informed PCR as a New Investigational Approach for Analysis of Outbreak-Associated Mycobacterium tuberculosis Isolates 10.1128/JCM.42.5.1890-1896.2004

Characterization of a haemolysin from Mycobacterium tuberculosis with homology to a virulence factor of Serpulina hyodysenteriae 10.1099/00221287-144-5-1205

Mycobacterium tuberculosis expresses a novel pH-dependent divalent cation transporter belonging to the Nramp family 10.1084/jem.190.5.717

Molecular epidemiology of tuberculosis in London 1995-7 showing low rate of active transmission 10.1136/mp.56.2.121

Application of the polymerase chain reaction to the diagnosis of human toxoplasmosis 10.1016/0163-4453(93)92788-X

Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria 10.1371/journal.pone.0184510

DNA microarrays for virus detection in cases of central nervous system infection 10.1128/JCM.42.12.5811-5818.2004

Antibodies to gut protozoa in commercial immunoglobulin preparations 10.1016/0035-9203(91)90163-S

cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG 10.1099/00221287-147-8-2293

Benzothiazinones Kill Mycobacterium tuberculosis by blocking Arabinan synthesis 10.1126/science.1171583

Methionine sulfoximine resistance in mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1 10.1089/mdr.2010.0125

Whole genome analysis using microarrays 10.1007/978-1-59745-207-6_6

Genome sequencing and characterization of an extensively drug-resistant sequence type 111 serotype O12 hospital outbreak strain of Pseudomonas aeruginosa 10.1111/1469-0691.12528

Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide 10.1128/JB.182.22.6358-6365.2000

A polymerase chain reaction to detect a spliced late transcript of human cytomegalovirus in the blood of bone marrow transplant recipients 10.1016/0166-0934(95)01900-6

Differential expression of mycobacterial proteins following phagocytosis by macrophages 10.1099/00221287-147-2-459

Mycobacterial P 1-Type ATPases mediate resistance to Zinc poisoning in human macrophages 10.1016/j.chom.2011.08.006

Advanced significance analysis of microarray data based on weighted resampling: A comparative study and application to gene deletions in Mycobacterium bovis 10.1093/bioinformatics/btg417

BμG@Sbase - A microbial gene expression and comparative genomic database 10.1093/nar/gkr796

Genetic Composition of Mycobacterium bovis BCG Substrain Sofia [2] 10.1128/JCM.41.11.5349.2003

A comparative study of haemoglobins from the artiodactyla by isoelectric focusing 10.1016/0305-0491(77)90025-6

XDR-TB transmission in London: Case management and contact tracing investigation assisted by early whole genome sequencing 10.1016/j.jinf.2016.04.037

Haemoglobins and erythrocyte sickling in the artiodactyla: A survey 10.1016/0300-9629(77)90134-7

Cytokine mRNA expression in Mycobacteriam ulcerans-infected human skin and correlation with local inflammatory response 10.1128/IAI.74.5.2917-2924.2006

Clinical application of whole-genome sequencing to inform treatment for multidrug-resistant tuberculosis cases 10.1128/JCM.02993-14

High-dose rifapentine with moxifloxacin for pulmonary tuberculosis 10.1056/NEJMoa1314210

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum 10.1371/journal.pmed.0050075

Performance evaluation of automated urine microscopy as a rapid, non-invasive approach for the diagnosis of non-gonococcal urethritis 10.1136/sextrans-2014-051761

The nature of erythrocyte sickling in sheep 10.1016/0300-9629(79)90462-6

Serodiagnosis of giardiasis 10.1016/0888-0786(87)90001-1

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages 10.1371/journal.pone.0001403

Comparative studies on the glycoprotein composition of mammalian platelets 10.1016/0305-0491(77)90240-1

Design, validation, and application of a seven-strain Staphylococcus aureus PCR product microarray for comparative genomics 10.1128/AEM.71.11.7504-7514.2005

Drug resistant TB: UK multicentre study (DRUMS): Treatment, management and outcomes in London and West Midlands 2008–2014 10.1016/j.jinf.2016.12.005

Comparison of human low-molecular-weight RNA from normal and Crohn's disease derived blood and mesenteric, lymph node leucocytes 10.1042/bst0121112

Microarrays for microbes: The BμGΣ approach 10.1002/cfg.187

Gene expression during host—pathogen interactions: Approaches to bacterial mRNA extraction and labelling for microarray analysis 10.1016/S0580-9517(02)33009-5

Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity 10.1101/gr.185801

Microarray-based comparative genomics: Genome plasticity in Mycobacterium bovis 10.1002/cfg.182

The heat shock response of Mycobacterium tuberculosis: Linking gene expression, immunology and pathogenesis 10.1002/cfg.183

Prevalence of giardia in dogs and cats in the United Kingdom: Survey of an essex veterinary clinic 10.1016/0035-9203(89)90330-1

Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states 10.1098/rsob.140106

The 1st Symposium of the Wellcome Trust-funded Multi-collaborative Microbial Pathogen Microarray Facility - BμGΣ 2002: 'Bacterial pathogens, microarrays and functional genomics' 10.1002/cfg.189

Human cytomegalovirus genome sequences in lymph nodes 10.1016/S1286-4579(99)80023-9

Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial 10.1186/s12916-017-0834-4

The electrophoretic analysis of low molecular weight nucleic acids from Crohn's disease tissues in the search for an unconventional small infections agent 10.1007/BF01310895

Modulation of pristane-induced arthritis by mycobacterial antigens 10.3109/08916939108994706

Association of cytomegalovirus infection with post‐transplantation cardiac rejection as studied using the polymerase chain reaction 10.1002/jmv.1890420412

Gene markers in 40 Przewalski horses: Equus przewahkii 10.1111/j.1748-1090.1979.tb00570.x

Clinical use of whole genome sequencing for Mycobacterium tuberculosis 10.1186/s12916-016-0598-2

Early detection of cytomegalovirus (CMV) infection in bone marrow transplant patients by reverse transcription-PCR for CMV spliced late gene UL21.5: A two site evaluation 10.1016/S1386-6532(01)00209-8

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence 10.1128/IAI.74.1.88-98.2006

Molecular epidemiology of tuberculosis in London 1995-7 showing low rate of active transmission 10.1136/thorax.57.7.617

Development of an in vitro model of Toxoplasma gondii cyst formation 10.1111/j.1574-6968.1993.tb06593.x

Quantification of cytomegalovirus DNA in blood specimens from bone marrow transplant recipients by the polymerase chain reaction 10.1016/0166-0934(94)90077-9

Microarray analysis of whole genome expression of intracellular Mycobacterium tuberculosis 10.2174/156652407780598548

Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters 10.1016/j.femsle.2004.02.028

Genomic analysis of Mycobacterium tuberculosis complex strains used for production of purified protein derivative 10.1128/JCM.41.8.3929-3932.2003

Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: Identification of a novel wax ester 10.1099/mic.0.2006/004317-0

Minisatellites corresponding to the human polycore probes 33.6 and 33.15 in the genome of the most 'primitive' known eukaryote Giardia lamblia 10.1016/0378-1119(95)00572-5

Determination of Mycobacterium leprae Viability by Polymerase Chain Reaction Amplification of 71-kDa Heat-Shock Protein mRNA 10.1093/infdis/168.3.799

Microarrays reveal that each of the ten dominant lineages of Staphylococcus aureus has a unique combination of surface-associated and regulatory genes 10.1128/JB.188.2.669-676.2006

Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment 10.1084/jem.20030846

Point-of-care antibiotic susceptibility testing for gonorrhoea: Improving therapeutic options and sparing the use of cephalosporins 10.1136/sti.2010.044230

Kinetics of the in vitro gelation of a sickling haemoglobin from hog deer (Axis porcinus) 10.1016/0005-2795(79)90070-9

Evolutionary relationships among strains of Mycobacterium tuberculosis with few copies of IS6110 10.1128/JB.185.8.2555-2562.2003

Mycobacterium tuberculosis expresses two chaperonin-60 homologs 10.1073/pnas.90.7.2608

Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies 10.1186/1471-2164-9-94

Efficient translation and polyribosome binding of ¹²⁵I-labelled rabbit globin messenger ribonucleoprotein 10.1016/0014-5793(83)80130-6

Microarrays for Mycobacterium tuberculosis 10.1016/j.tube.2004.01.002

Prevalence and clinical correlations of genetic subtypes of Giardia lamblia in an urban setting 10.1017/S0950268810000208

RNA profiling in host-pathogen interactions 10.1016/j.mib.2007.05.013

The in vitro model of tissue cyst formation in Toxoplasma gondii 10.1016/0169-4758(94)90148-1

Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy 10.1186/s12916-016-0609-3

Mycobacterium tuberculosis DNA repair in response to subinhibitory concentrations of ciprofloxacin 10.1093/jac/dkn387

Professor D A Mitchison: 60 years of contributions to the chemotherapy of tuberculosis 10.1016/j.tube.2010.03.004

Accurate detection of Neisseria gonorrhoeae ciprofloxacin susceptibility directly from genital and extragenital clinical samples: Towards genotype-guided antimicrobial therapy 10.1093/jac/dkv432

High prevalence of antibiotic-resistant mycoplasma genitalium in nongonococcal urethritis: The need for routine testing and the inadequacy of current treatment options 10.1093/cid/cit752

An effective method of RNA extraction from bacteria refractory to disruption, including mycobacteria 10.1093/nar/25.3.675

Protein synthesis is shutdown in dormant Mycobacterium tuberculosis and is reversed by oxygen or heat shock 10.1016/S0378-1097(97)00514-4

Genomic diversity among Beijing and non-Beijing Mycobacterium tuberculosis isolates from Myanmar 10.1371/journal.pone.0001973

Polyribosome binding of rabbit globin messenger RNA and messenger ribonucleoprotein labelled with bacteriophage-T4 RNA ligase and 5′-[³²P] phosphocytidine 3′-phosphate 10.1093/nar/11.1.1

Recognition of tissue cyst-specific antigens in reactivating toxoplasmosis 10.1099/00222615-46-7-587

Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages 10.1371/journal.pone.0011066

New strategies in microbiological diagnosis 10.1016/0195-6701(91)90017-3

Characterisation of bovine leukocyte ig-like receptors 10.1371/journal.pone.0034291

Quantitation of Toxoplasma gondii DNA in a competitive nested polymerase chain reaction 10.1136/jcp.52.1.61

Variation in Salmonella enterica serovar typhi IncHI1 plasmids during the global spread of resistant typhoid fever 10.1128/AAC.00645-08

Estimation of the rate of unrecognized cross-contamination with Mycobacterium tuberculosis in London Microbiology Laboratories 10.1128/JCM.40.11.4100-4104.2002

Use of DNA arrays to study transcriptional responses to antimycobacterial compounds. 10.1007/978-1-60327-279-7_6

DNA probes for the faecal diagnosis of Giardia lamblia infections in man 10.1042/bst0170363

The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis 10.1016/j.tube.2003.12.011

Oleoyl coenzyme a regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria 10.1074/jbc.M114.577338

Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: A model for persistent organisms? 10.1016/j.tube.2003.12.010

Examining the basis of isoniazid tolerance in nonreplicating Mycobacterium tuberculosis using transcriptional profiling 10.4155/fmc.10.219

Characterization of the heat shock response in Mycobacterium bovis BCG 10.1128/jb.173.24.7982-7987.1991

Diagnosis of Pneumocystis carinii pneumonia: Immunofluorescence staining, simple PCR or nPCR 10.1016/S0163-4453(99)90106-8

Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions 10.1128/AAC.02774-13

Extraction and characterization of mRNA from mycobacteria: implication for virulence gene identification 10.1016/0167-7012(91)90010-N

The use of DNA probes identifying restriction‐fragment‐length polymorphisms to examine the Mycobacterium avium complex 10.1111/j.1365-2958.1987.tb01934.x

An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome 10.1038/s41598-019-41692-2

Platelet shape change: Induction by trypsin and release of an acidic macroglycopeptide from washed human platelets and from those of three cases of glanzmann’s thrombasthenia 10.1159/000214057

Diagnostic accuracy of a prototype rapid chlamydia and gonorrhoea recombinase polymerase amplification assay: a multicentre cross-sectional preclinical evaluation 10.1016/j.cmi.2018.06.003

Simon Waddell

Waddell Simon

ORCID: 0000-0002-3684-9116

http://www.bsms.ac.uk/research/our-researchers/simon-waddell/

Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase 10.1097/CCM.0b013e3182186d27

Mycobacterial P 1-Type ATPases mediate resistance to Zinc poisoning in human macrophages 10.1016/j.chom.2011.08.006

Methionine sulfoximine resistance in mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1 10.1089/mdr.2010.0125

Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease 10.1164/rccm.201104-0715OC

Effects of low incubation temperatures on the bactericidal activity of anti-tuberculosis drugs 10.1093/jac/dkq414

Distance-based differential analysis of gene curves 10.1093/bioinformatics/btr528

Use of DNA arrays to study transcriptional responses to antimycobacterial compounds. 10.1007/978-1-60327-279-7_6

Reprogramming the Mycobacterium tuberculosis transcriptome during pathogenesis 10.1016/j.ddmec.2010.09.007

Examining the basis of isoniazid tolerance in nonreplicating Mycobacterium tuberculosis using transcriptional profiling 10.4155/fmc.10.219

Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages 10.1371/journal.pone.0011066

Benzothiazinones Kill Mycobacterium tuberculosis by blocking Arabinan synthesis 10.1126/science.1171583

Adjusting to a new home: Mycobacterium tuberculosis gene expression in response to an intracellular lifestyle 10.2217/fmb.09.94

Whole genome analysis using microarrays 10.1007/978-1-59745-207-6_6

Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies 10.1186/1471-2164-9-94

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum 10.1371/journal.pmed.0050075

RNA profiling in host-pathogen interactions 10.1016/j.mib.2007.05.013

Quantification of global transcription patterns in prokaryotes using spotted microarrays 10.1186/gb-2007-8-12-r265

Microarray analysis of whole genome expression of intracellular Mycobacterium tuberculosis 10.2174/156652407780598548

Inactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37Rv 10.1111/j.1472-765X.2005.01659.x

Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-γ 10.1172/JCI19316

The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds 10.1016/j.tube.2003.12.005

Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters 10.1016/j.femsle.2004.02.028

Understanding anti-tuberculosis drug efficacy: Rethinking bacterial populations and how we model them 10.1016/j.ijid.2014.11.028

Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states 10.1098/rsob.140106

Oleoyl coenzyme a regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria 10.1074/jbc.M114.577338

Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions 10.1128/AAC.02774-13

Host-pathogen interactions 10.1007/978-1-4614-4966-9_6

Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood Cells 10.1371/journal.pone.0009753

Intracellular Microbe Whole-Genome Expression Profiling: Methodological Considerations and Biological Inferences 10.1002/9783527629176.ch9

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages. 10.1371/journal.pone.0001403

Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy 10.1186/s12916-016-0609-3

Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters 10.1111/j.1574-6968.2004.tb09500.x

A non-canonical mismatch repair pathway in prokaryotes 10.1038/ncomms14246

A Novel TetR-like transcriptional regulator is induced in acid-nitrosative stress and controls expression of an efflux pump in mycobacteria 10.3389/fmicb.2017.02039

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function 10.1371/journal.pone.0185973

Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death. 10.1172/jci.insight.96773

Transcriptional profiling Mycobacterium tuberculosis from patient sputa 10.1007/978-1-4939-7638-6_11

Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel 10.1021/acs.jmedchem.8b01325

Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112 10.1111/mmi.14398

Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West Pakistan 10.1038/s41598-019-51562-6

The use of transcriptomics to predict drug efficacy and treatment outcome in tuberculosis 10.4155/9781910419144

Spontaneously Occurring Small-Colony Variants of Staphylococcus aureus Show Enhanced Clearance by THP-1 Macrophages. 10.3389/fmicb.2020.01300

cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG 10.1099/00221287-147-8-2293

Identification of antigens presented by MHC for vaccines against tuberculosis 10.1038/s41541-019-0148-y

Multi-omics technologies applied to tuberculosis drug discovery 10.3390/app10134629

Carprofen elicits pleiotropic mechanisms of bactericidal action with the potential to reverse antimicrobial drug resistance in tuberculosis 10.1093/jac/dkaa307

Characterization of the Mycobacterial MSMEG-3762/63 Efflux Pump in Mycobacterium smegmatis Drug Efflux 10.3389/fmicb.2020.575828

Search for Antimicrobial Activity Among Fifty-Two Natural and Synthetic Compounds Identifies Anthraquinone and Polyacetylene Classes That Inhibit Mycobacterium tuberculosis 10.3389/fmicb.2020.622629

Weighted gene co-expression network analysis identifies key modules and hub genes associated with mycobacterial infection of human macrophages 10.3390/antibiotics10020097

Three-dimensional low shear culture of Mycobacterium bovis BCG induces biofilm formation and antimicrobial drug tolerance 10.1038/s41522-021-00186-8

Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity 10.1172/jci.insight.145704

Correction to: Lu et al. weighted gene co-expression network analysis identifies key modules and hub genes associated with mycobacterial infection of human macrophages. antibiotics 2021, 10, 97 10.3390/antibiotics10070792

Undetected carriage explains apparent Staphylococcus aureus acquisition in a non-outbreak healthcare setting 10.1016/j.jinf.2021.07.016

Evolving droplet dynamics during violent expiratory events at various ambient environments 10.1615/AtomizSpr.2021037116

Jakob Albrethsen

Albrethsen Jakob

ORCID: 0000-0002-2842-1128

Clinical proteomics: Insights from IGF-I. 10.1016/j.cca.2017.11.034

Mining the granule proteome: a potential source of endocrine biomarkers. 10.2217/bmm.14.107

Atrial natriuretic peptides in plasma. 10.1016/j.cca.2014.08.017

Adropin: a new regulatory peptide in cardiovascular endocrinology. 10.1016/j.regpep.2014.04.002

Proteomics of differential extraction fractions enriched for chromatin-binding proteins from colon adenoma and carcinoma tissues. 10.1016/j.bbapap.2013.12.006

Proteomics of cancer cell lines resistant to microtubule-stabilizing agents. 10.1158/1535-7163.mct-13-0471

Proteomic profiling of Mycobacterium tuberculosis identifies nutrient-starvation-responsive toxin-antitoxin systems. 10.1074/mcp.m112.018846

Candidate biomarker verification: Critical examination of a serum protein pattern for human colorectal cancer. 10.1002/prca.201100095

Gel-based proteomics of liver cancer progression in rat. 10.1016/j.bbapap.2011.05.018

The first decade of MALDI protein profiling: a lesson in translational biomarker research. 10.1016/j.jprot.2011.02.027

Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression. 10.1074/mcp.m900546-mcp200

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis. 10.1126/science.1171583

Evaluation of a type 1 diabetes serum cohort by SELDI-TOF MS protein profiling. 10.1002/prca.200800063

Unravelling the nuclear matrix proteome. 10.1016/j.jprot.2008.09.005

Reproducibility in protein profiling by MALDI-TOF mass spectrometry. 10.1373/clinchem.2006.082644

The Arabidopsis ADP-ribosylation factor (ARF) and ARF-like (ARL) system and its regulation by BIG2, a large ARF-GEF 10.1016/j.plantsci.2006.07.002

Human neutrophil peptides 1, 2 and 3 are biochemical markers for metastatic colorectal cancer. 10.1016/j.ejca.2006.05.039

Preanalytical and analytical variation of surface-enhanced laser desorption-ionization time-of-flight mass spectrometry of human serum. 10.1515/cclm.2006.228

Upregulated expression of human neutrophil peptides 1, 2 and 3 (HNP 1-3) in colon cancer serum and tumours: a biomarker study. 10.1186/1471-2407-5-8

FYVE zinc-finger proteins in the plant model Arabidopsis thaliana: identification of PtdIns3P-binding residues by comparison of classic and variant FYVE domains. 10.1042/0264-6021:3590165

Development and validation of a mass spectrometry-based assay for quantification of insulin-like factor 3 in human serum 10.1515/cclm-2018-0171

Evaluation of Serum Insulin-like Factor 3 Quantification by LC-MS/MS as a Biomarker of Leydig Cell Function. 10.1210/clinem/dgaa145

Longitudinal Increases in Serum Insulin-like Factor 3 and Testosterone Determined by LC-MS/MS in Pubertal Danish Boys 10.1210/clinem/dgaa496

Serum insulin-like factor 3 quantification by LC–MS/MS in male patients with hypogonadotropic hypogonadism and Klinefelter syndrome 10.1007/s12020-021-02609-0

Serum Insulin-like Factor 3 Levels Are Reduced in Former Androgen Users, Suggesting Impaired Leydig Cell Capacity 10.1210/clinem/dgab129

Neeraj Dhar

Dhar Neeraj

ORCID: 0000-0002-5887-8137

Dynamic Persistence of Antibiotic-Stressed Mycobacteria 10.1126/science.1229858

Mycobacterium tuberculosisEspB binds phospholipids and mediates EsxA-independent virulence 10.1111/mmi.12336

Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria 10.1038/ncomms3470

EspD Is Critical for the Virulence-Mediating ESX-1 Secretion System in Mycobacterium tuberculosis 10.1128/JB.06417-11

Malachite Green Interferes with Postantibiotic Recovery of Mycobacteria 10.1128/AAC.00406-12

Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis 10.1128/AAC.01125-12

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis 10.1126/scitranslmed.3004395

Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis 10.1016/j.vaccine.2011.07.039

Development of a repressible mycobacterial promoter system based on two transcriptional repressors 10.1093/nar/gkq235

Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice 10.1073/pnas.1003219107

Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis 10.1128/AAC.00821-10

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 10.1126/science.1171583

Boosting with a DNA vaccine expressing ESAT-6 (DNAE6) obliterates the protection imparted by recombinant BCG (rBCGE6) against aerosol Mycobacterium tuberculosis infection in guinea pigs 10.1016/j.vaccine.2009.09.121

Enhanced and Enduring Protection against Tuberculosis by Recombinant BCG-Ag85C and Its Association with Modulation of Cytokine Profile in Lung 10.1371/journal.pone.0003869

Microbial phenotypic heterogeneity and antibiotic tolerance 10.1016/j.mib.2006.12.007

Elicitation of efficient, protective immune responses by using DNA vaccines against tuberculosis 10.1016/j.vaccine.2005.03.056

Increased expression of Mycobacterium tuberculosis 19 kDa lipoprotein obliterates the protective efficacy of BCG by polarizing host immune responses to the Th2 subtype 10.1111/j.1365-3083.2005.01569.x

Immunogenicity of recombinant BCG vaccine strains overexpressing components of the antigen 85 complex of Mycobacterium tuberculosis 10.1007/s00430-002-0170-x

Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs 10.1046/j.1365-2958.2003.03712.x

Modulation of host immune responses by overexpression of immunodominant antigens of Mycobacterium tuberculosis in bacille Calmette-Guerin 10.1046/j.1365-3083.2003.01321.x

Skewing of the Th1/Th2 responses in mice due to variation in the level of expression of an antigen in a recombinant BCG system 10.1016/S0165-2478(03)00043-9

4-Aminoquinolone Piperidine Amides: Noncovalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity 10.1021/jm5005978

Assessing the essentiality of the decaprenyl-phospho-D-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants 10.1111/mmi.12546

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism 10.1038/ncomms4369

Dielectrophoresis-based purification of antibiotic-treated bacterial subpopulations 10.1039/c4lc00109e

In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis 10.1128/AAC.02410-14

Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate with Attenuation of Virulence 10.1128/JB.00967-13

Bioluminescence for assessing drug potency against nonreplicating Mycobacterium tuberculosis 10.1128/AAC.00528-15

2-carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1 10.1021/cb5007163

Rapid cytolysis of mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic 10.1128/AAC.03461

Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells 10.1016/j.chom.2014.12.008

Stress and host immunity amplify mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms 10.1016/j.chom.2014.11.016

Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy 10.1007/978-1-4939-2450-9_14

Simple and rapid method to determine antimycobacterial potency of compounds by using autoluminescent mycobacterium tuberculosis 10.1128/AAC.03205-14

The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo 10.1128/JB.01346-13

EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis 10.1111/mmi.12718

Recombinant BCG approach for development of vaccines: Cloning and expression of immunodominant antigens of M. tuberculosis 10.1016/S0378-1097(00)00353-0

Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β- d -ribose Oxidase 10.1021/acsinfecdis.5b00065

Combinations of β-lactam antibiotics currently in clinical trials are efficacious in a dhp-i-deficient mouse model of tuberculosis infection 10.1128/AAC.01063-15

Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic 10.1128/AAC.03461-14

Erratum to The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo [Journal of Bacteriology, 196, 19, (2014) 3441-3451] DOI: 10.1128/JB.02332-14 10.1128/JB.02332-14

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor 10.1016/j.ebiom.2016.05.006

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria 10.1111/mmi.13535

An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division 10.1038/s41598-017-01184-7

Division site selection linked to inherited cell surface wave troughs in mycobacteria 10.1038/nmicrobiol.2017.94

Elucidating the role of (p)ppGpp in mycobacterial persistence against antibiotics 10.1002/iub.1888

Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress 10.15252/embj.2019101876

Computational Analysis of the Mutual Constraints between Single‐Cell Growth and Division Control Models 10.1002/adbi.201900103

A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis 10.1101/2020.02.03.931170

Driving polar growth 10.7554/eLife.57043

Dielectrophoresis as a single cell characterization method for bacteria 10.1088/2057-1976/3/1/015005

Early invasion of uropathogenic Escherichia coli into the bladder wall by solitary bacteria that are protected from antibiotics and neutrophil swarms in an organoid model 10.1101/2020.10.29.358622

A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth 10.7554/eLife.59961

Dynamic persistence of intracellular bacterial communities of uropathogenic Escherichia coli in a human bladder-chip model of urinary tract infections 10.1101/2021.01.03.424836

Rapid endotheliitis and vascular damage characterize SARS‐CoV‐2 infection in a human lung‐on‐chip model 10.15252/embr.202152744

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection 10.7554/eLife.66481

Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model 10.1016/j.celrep.2021.109351

Jana Korduláková

Korduláková Jana

ORCID: 0000-0003-2834-0165

New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action 10.1016/j.ejmech.2018.04.017

Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria. 10.1074/jbc.ra117.000246

Mechanochemical synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity 10.3390/molecules22091457

Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression 10.1038/srep43495

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria 10.1111/mmi.13535

Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis 10.1016/j.ejmech.2016.07.028

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA 10.1038/ncomms10906

Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth 10.1016/j.ejmech.2015.06.035

DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization 10.1021/acschembio.5b00237

Lead selection and characterization of antitubercular compounds using the Nested Chemical Library 10.1016/j.tube.2015.02.028

Covalent Modification of the Mycobacterium tuberculosis FAS-II Dehydratase by Isoxyl and Thiacetazone 10.1021/id500032q

Erratum for Ang et al., An ethA-ethR-Deficient Mycobacterium bovis BCG Mutant Displays Increased Adherence to Mammalian Cells and Greater Persistence In Vivo, Which Correlate with Altered Mycolic Acid Composition. 10.1128/IAI.02884-14

Erratum for Boldrin et al., The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo. 10.1128/JB.02332-14

The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo 10.1128/JB.01346-13

Purification and characterization of the acyltransferase involved in biosynthesis of the major mycobacterial cell envelope glycolipid--monoacylated phosphatidylinositol dimannoside. 10.1016/j.pep.2014.04.014

An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition 10.1128/IAI.01332-13

A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria 10.1074/jbc.M112.400986

A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone 10.1074/jbc.M112.400994

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane 10.1038/nchembio.794

Investigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster 10.4149/gpb_2011_03_239

The structure-activity relationship of urea derivatives as anti-tuberculosis agents 10.1016/j.bmc.2011.07.034

Synthesis, biological activity, and evaluation of the mode of action of novel antitubercular benzofurobenzopyrans substituted on A ring 10.1016/j.ejmech.2010.09.048

Molecular Basis of Phosphatidyl-myo-inositol Mannoside Biosynthesis and Regulation in Mycobacteria 10.1074/jbc.R110.168328

AftD, a novel essential arabinofuranosyltransferase from mycobacteria 10.1093/glycob/cwp116

Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria. Implications for catalysis 10.1074/jbc.M109.003947

Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives 10.3390/ijms22062884

Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of Mycobacterium species 10.1074/jbc.M303639200

Erratum: Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors (Journal of Medicinal Chemistry (2020) 63:9 (4749-4761) DOI: 10.1021/acs.jmedchem.0c00007) 10.1021/acs.jmedchem.0c01187

The Two-Component Locus MSMEG_0244/0246 Together With MSMEG_0243 Affects Biofilm Assembly in M. smegmatis Correlating With Changes in Phosphatidylinositol Mannosides Acylation 10.3389/fmicb.2020.570606

Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis 10.1107/S1744309105012364

Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis 10.1074/jbc.M702676200

Fragment-based design of mycobacterium tuberculosis inha inhibitors 10.1021/acs.jmedchem.0c00007

Trehalose Conjugation Enhances Toxicity of Photosensitizers against Mycobacteria 10.1021/acscentsci.8b00962

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents 10.1016/j.chembiol.2019.02.013

Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria 10.1074/jbc.M702087200

Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β- d -ribofuranose 2′-Oxidase 10.1021/acs.jmedchem.9b00912

Benzothiazinones Kill Mycobacterium tuberculosis by blocking Arabinan synthesis 10.1126/science.1171583

Alkylamino derivatives of N-benzylpyrazine-2-carboxamide: synthesis and antimycobacterial evaluation 10.1039/c5md00178a

Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis 10.1128/AAC.00433-07

New Insights into the Mechanism of Action of the Thienopyrimidine Antitubercular Prodrug TP053 10.1021/acsinfecdis.9b00388

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis: PimA is essential for growth of mycobacteria 10.1074/jbc.M204060200

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis 10.1371/journal.ppat.0030062

Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall 10.1128/JB.00489-06

A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 10.1021/acsinfecdis.0c00325

Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 10.1021/acsinfecdis.0c00622

p-hydroxybenzoic acid synthesis in Mycobacterium tuberculosis 10.1074/jbc.M508332200

Silvia Buroni

Buroni Silvia

ORCID: 0000-0002-6979-2275

Email: silvia.buroni@unipv.it

Mycobacterium tuberculosis: Drug resistance and future perspectives 10.2217/fmb.09.20

Exploring the HME and HAE1 efflux systems in the genus Burkholderia 10.1186/1471-2148-10-164

Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis 10.1126/scitranslmed.3004395

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 10.1371/journal.pone.0026675

Glutamine amidotransferase activity of NAD⁺ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain 10.1016/j.resmic.2004.08.011

Molecular mechanisms of chlorhexidine tolerance in Burkholderia cenocepacia biofilms 10.1128/AAC.01571-10

Decaprenylphosphoryl-β-D-ribose 2'-epimerase from Mycobacterium tuberculosis is a magic drug target 10.2174/092986710791959693

MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 10.1128/AAC.05270-11