Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
Heather Hulme
Lynsey M. Meikle
Nicole Strittmatter
Justin J. J. van der Hooft
John Swales
Ryan A. Bragg
Victor H. Villar
Michael J. Ormsby
Stephanie Barnes
Sheila L. Brown
Alex Dexter
Maya T. Kamat
Jasper C. Komen
Daniel Walker
Simon Milling
Emily K. Osterweil
Andrew S. MacDonald
Chris J. Schofield
Saverio Tardito
Josephine Bunch
Gillian Douce
Julia M. Edgar
RuAngelie Edrada-Ebel
Richard J. A. Goodwin
Richard Burchmore
Daniel M. Wall
Science Advances, 2020-3
VICTOR H. VILLAR
VILLAR VICTOR H.
/ Villar VH
/ Villar VH
ORCID: 0000-0003-2837-5018
Oleanolic and maslinic acid Sensitize soft tissue sarcoma Cells to Doxorubicin by inhibiting the multidrug resistance protein mrp-1, but not p-glycoprotein
10.1016/j.jnutbio.2013.12.003
Glutaminolysis and autophagy in cancer
10.1080/15548627.2015.1053680
mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation.
10.1038/ncomms14124
Glutamoptosis: A new cell death mechanism inhibited by autophagy during nutritional imbalance.
10.1080/15548627.2017.1299315
Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR
10.1080/23723556.2017.1297284
Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma
10.1371/journal.pone.0155946
Down-regulation of the AKT/GSK3β/β-catenin signalling pathway by the triterpene ursolic acid induced intrinsic apoptosis in human soft tissue sarcomas
10.1016/j.chemphyslip.2010.05.083
Nilotinib as Coadjuvant Treatment with Doxorubicin in Patients with Sarcomas: A Phase I Trial of the Spanish Group for Research on Sarcoma
10.1158/1078-0432.CCR-18-0851
Nilotinib counteracts P-glycoprotein-mediated multidrug resistance and synergizes the antitumoral effect of doxorubicin in soft tissue sarcomas
10.1371/journal.pone.0037735
ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion
10.1007/s11010-010-0418-5
SKIP is required for TGF-β1-induced epithelial mesenchymal transition and migration in transformed keratinocytes
10.1016/j.febslet.2010.10.020
Spred2 inhibits TGF-β1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition
10.1002/ijc.25045
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
10.1126/sciadv.aax6328
Skip Regulates TGF-β1-Induced Extracellular Matrix Degrading Proteases Expression in Human PC-3 Prostate Cancer Cells
10.1155/2013/398253
Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis
10.1038/s41467-021-25079-4
The Metabolic Features of Tumor-Associated Macrophages: Opportunities for Immunotherapy?
10.1155/2021/5523055
Maya Kamat
Kamat Maya
ORCID: 0000-0002-7792-2084
Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes [version 1; peer review: 3 approved]
10.12688/wellcomeopenres.15518.1
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
10.1126/sciadv.aax6328
Michael Ormsby
Ormsby Michael
ORCID: 0000-0002-3991-2336
Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori
10.1038/s41417-018-0039-9
Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori
10.1038/s41417-018-0047-9
Author Correction: Increasing the bactofection capacity of a mammalian expression vector by removal of the f1 ori
10.1038/s41417-019-0086-x
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
10.1126/sciadv.aax6328
Justin van der Hooft
van der Hooft Justin
/ Justin J.J. van der Hooft
ORCID: 0000-0002-9340-5511
Structural elucidation of low abundant metabolites in complex sample matrices
10.1007/s11306-013-0519-8
Non-smoky GLYCOSYLTRANSFERASE1 prevents the release of smoky aroma from tomato fruit
10.1105/tpc.113.114231
Automatic chemical structure annotation of an LC-MSn based metabolic profile from green tea
10.1021/ac400861a
Substructure-based annotation of high-resolution multistage MSn spectral trees
10.1002/rcm.6364
Structural annotation and elucidation of conjugated phenolic compounds in black, green, and white tea extracts
10.1021/jf300297y
Structural elucidation and quantification of phenolic conjugates present in human urine after tea intake
10.1021/ac3017339
Spectral trees as a robust annotation tool in LC-MS based metabolomics
10.1007/s11306-011-0363-7
Metabolite identification using automated comparison of high-resolution multistage mass spectral trees
10.1021/ac2034216
Inhibitory activity of plumbagin produced by Drosera intermedia on food spoilage fungi
10.1002/jsfa.5522
A strategy for fast structural elucidation of metabolites in small volume plant extracts using automated MS-guided LC-MS-SPE-NMR
10.1002/mrc.2833
Thermal diffusivity of periderm from tomatoes of different maturity stages as determined by the concept of the frequency-domain open photoacoustic cell
10.1063/1.3530735
Polyphenol identification based on systematic and robust high-resolution accurate mass spectrometry fragmentation
10.1021/ac102546x
Iridoid and caffeoyl phenylethanoid glycosides of the endangered carnivorous plant Pinguicula lusitanica L. (Lentibulariaceae)
10.1016/j.bse.2009.05.003
Topic modeling for untargeted substructure exploration in metabolomics
10.1073/pnas.1608041113
Propagating annotations of molecular networks using in silico fragmentation
10.1371/journal.pcbi.1006089
Did a plant-herbivore arms race drive chemical diversity in Euphorbia?
10.1101/323014
Automatic Compound Annotation from Mass Spectrometry Data Using MAGMa.
10.5702/massspectrometry.S0033
Interactions of blacktea polyphenols with human gut microbiota: implications for gut and cardiovascular health
10.3945/ajcn.113.058263
Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes
10.1111/tpj.13527
Enhanced Acylcarnitine Annotation in High-Resolution Mass Spectrometry Data: Fragmentation Analysis for the Classification and Annotation of Acylcarnitines
10.3389/fbioe.2015.00026
Rapid and sustained systemic circulation of conjugated gut microbiol catabolites after single-dose black tea extract consumption
10.1021/pr5001253
In Silico Prediction and Automatic LC–MSn Annotation of Green Tea Metabolites in Urine
10.1021/ac403875b
Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose
10.1007/s11306-018-1438-5
Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae
10.1101/463620
Deciphering complex metabolite mixtures by unsupervised and supervised substructure discovery and semi-automated annotation from MS/MS spectra
10.1101/491506
Accelerating metabolite identification in natural product research: toward an ideal combination of LC-HRMS/MS and NMR profiling, in silico databases and chemometrics
10.1021/acs.analchem.8b05112
Untargeted Mass Spectrometry-Based Metabolomics Tracks Molecular Changes in Raw and Processed Foods and Beverages
10.1101/347716
Absorption, metabolism, distribution and excretion of (−)-epicatechin: A review of recent findings
https://doi.org/10.1016/j.mam.2017.11.002
Metabolite Identification in Complex Mixtures Using Nuclear Magnetic Resonance Spectroscopy
10.1007/978-3-319-28275-6_6-2
Ms2lda.org: web-based topic modelling for substructure discovery in mass spectrometry
10.1093/bioinformatics/btx582
A comprehensive evaluation of the [2-14C](–)-epicatechin metabolome in rats
https://doi.org/10.1016/j.freeradbiomed.2016.08.001
The food metabolome: a window over dietary exposure
10.3945/ajcn.113.076133
Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols
10.3945/ajcn.113.058958
Unsupervised Discovery and Comparison of Structural Families Across Multiple Samples in Untargeted Metabolomics
10.1021/acs.analchem.7b01391
A community-driven paired data platform to accelerate natural product mining by combining structural information from genomes and metabolomes
10.18174/FAIRdata2018.16286
Implementations of the chemical structural and compositional similarity metric in R and Python
10.1101/546150
Comprehensive mass spectrometry-guided phenotyping of plant specialized metabolites reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae
10.1111/tpj.14292
A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters
10.1186/s13104-019-4222-3
The Metabolomics Society—Current State of the Membership and Future Directions
10.3390/metabo9050089
Deciphering complex metabolite mixtures by unsupervised and supervised substructure discovery and semi-automated annotation from MS/MS spectra
10.1039/C8FD00235E
MolNetEnhancer: enhanced molecular networks by integrating metabolome mining and annotation tools
10.1101/654459
Substantial extracellular metabolic differences found between phylogenetically closely related probiotic and pathogenic strains of Escherichia coli
10.3389/fmicb.2019.00252
Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia l.
10.3389/fpls.2019.00846
Molnetenhancer: Enhanced molecular networks by integrating metabolome mining and annotation tools
10.3390/metabo9070144
In Silico Optimization of Mass Spectrometry Fragmentation Strategies in Metabolomics
10.3390/metabo9100219
MIBiG 2.0: a repository for biosynthetic gene clusters of known function
10.1093/nar/gkz882
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages
10.1016/j.foodchem.2019.125290
The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery
10.1021/acscentsci.9b00806
Mass spectrometry searches using MASST
10.1038/s41587-019-0375-9
Assessing specialized metabolite diversity of Alnus species by a digitized LC–MS/MS data analysis workflow
10.1016/j.phytochem.2020.112292
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
10.1126/sciadv.aax6328
Chemically-informed Analyses of Metabolomics Mass Spectrometry Data with Qemistree
10.1101/2020.05.04.077636
Linking genomics and metabolomics to chart specialized metabolic diversity
10.1039/D0CS00162G
Reproducible molecular networking of untargeted mass spectrometry data using GNPS
10.1038/s41596-020-0317-5
Decomposing metabolite set activity levels with PALS
10.1101/2020.06.07.138974
Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions
10.1101/2020.06.12.148205
Phenylpropane as an Alternative Dearomatizing Unit of Indoles: Discovery of Inaequalisines A and B Using Substructure-Informed Molecular Networking
10.1021/acs.orglett.0c02153
matchms - processing and similarity evaluation of mass spectrometry data
10.1101/2020.08.06.239244
Spec2Vec: Improved mass spectral similarity scoring through learning of structural relationships
10.1101/2020.08.11.245928
BiG-SLiCE: A Highly Scalable Tool Maps the Diversity of 1.2 Million Biosynthetic Gene Clusters
10.1101/2020.08.17.240838
matchms - processing and similarity evaluation of mass spectrometry data.
10.21105/joss.02411
ReDU: a framework to find and reanalyze public mass spectrometry data
10.1038/s41592-020-0916-7
Feature-based molecular networking in the GNPS analysis environment
10.1038/s41592-020-0933-6
Rapid Development of Improved Data-dependent Acquisition Strategies
10.1101/2020.09.11.293092
Chemically informed analyses of metabolomics mass spectrometry data with Qemistree
10.1038/s41589-020-00677-3
Auto-deconvolution and molecular networking of gas chromatography–mass spectrometry data
10.1038/s41587-020-0700-3
The ant fungus garden acts as an external digestive system
10.1101/2020.11.18.389361
BiG-MAP: an automated pipeline to profile metabolic gene cluster abundance and expression in microbiomes
10.1101/2020.12.14.422671
BiG-SLiCE: A highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters
10.1093/gigascience/giaa154
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs
10.1371/journal.ppat.1008932
Comparative Metabologenomics Analysis of Polar Actinomycetes
10.3390/md19020103
Ranking Metabolite Sets by Their Activity Levels
10.3390/metabo11020103
Spec2Vec: Improved mass spectral similarity scoring through learning of structural relationships
10.1371/journal.pcbi.1008724
Rapid Development of Improved Data-Dependent Acquisition Strategies
10.1021/acs.analchem.0c03895
MS2DeepScore - a novel deep learning similarity measure for mass fragmentation spectrum comparisons
10.1101/2021.04.18.440324
Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions
10.1371/journal.pcbi.1008920
Metabolomics-Guided Elucidation of Plant Abiotic Stress Responses in the 4IR Era: An Overview
10.3390/metabo11070445
Chemical Gradients of Plant Substrates in an Atta texana Fungus Garden
10.1128/mSystems.00601-21
Comprehensive Large-Scale Integrative Analysis of Omics Data To Accelerate Specialized Metabolite Discovery
10.1128/mSystems.00726-21
Nicole Strittmatter
Strittmatter Nicole
ORCID: 0000-0003-1277-9608
Analysis of intact bacteria using rapid evaporative ionisation mass spectrometry
10.1039/c3cc42015a
Characterization and Identification of Clinically Relevant Microorganisms Using Rapid Evaporative Ionization Mass Spectrometry
10.1021/ac501075f
Mass Spectrometry Imaging of Cassette-Dosed Drugs for Higher Throughput Pharmacokinetic and Biodistribution Analysis
10.1021/ac502217r
Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer
10.1073/pnas.1310524111
Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging
10.1039/c3cc48927b
Unique metabolites protect earthworms against plant polyphenols
10.1038/ncomms8869
Network analysis of mass spectrometry imaging data from colorectal cancer identifies key metabolites common to metastatic development
10.1101/230052
Rapid Evaporative Ionization Mass Spectrometry Imaging Platform for Direct Mapping from Bulk Tissue and Bacterial Growth Media
10.1021/ac5046752
Repeatability and reproducibility of desorption electrospray ionization-mass spectrometry (DESI-MS) for the imaging analysis of human cancer tissue: a gateway for clinical applications
10.1039/c4ay01770f
Benchmark datasets for 3D MALDI- and DESI-imaging mass spectrometry
10.1186/s13742-015-0059-4
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo
10.1126/scitranslmed.aad2355
Shotgun Lipidomic Profiling of the NCI60 Cell Line Panel Using Rapid Evaporative Ionization Mass Spectrometry
10.1021/acs.analchem.6b00187
Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry
10.1016/j.neuroimage.2016.05.004
Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry
10.1158/0008-5472.can-16-0699
Epithelial ovarian carcinoma diagnosis by desorption electrospray ionization mass spectrometry imaging
10.1038/srep39219
Tumour regression and improved gastrointestinal tolerability from controlled release of SN-38 from novel polyoxazoline-modified dendrimers
10.1016/j.jconrel.2016.12.034
Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection
10.1038/s41598-017-03100-5
Translational utility of a hierarchical classification strategy in biomolecular data analytics
10.1038/s41598-017-14092-7
Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging
10.1021/acs.analchem.7b05239
A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability
10.1016/j.neuroimage.2018.01.013
Uncovering the regional localization of inhaled salmeterol retention in the lung
10.1080/10717544.2018.1455762
Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice
10.3389/fmolb.2018.00028
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging
10.1007/s11306-019-1531-4
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
10.1126/sciadv.aax6328
High-resolution 3D visualization of nanomedicine distribution in tumors
10.7150/thno.37178
Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging
10.1089/jamp.2019.1536
De novo lipogenesis alters the phospholipidome of esophageal adenocarcinoma
10.1158/0008-5472.can-19-4035
Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry
10.1158/0008-5472.can-14-2258
Analysis of wastewater samples by direct combination of thin-film microextraction and desorption electrospray ionization mass spectrometry
10.1039/c2an35411j
Universal Sample Preparation Unlocking Multimodal Molecular Tissue Imaging
10.1021/acs.analchem.0c00826
Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds
10.1021/jasms.0c00166
Ambient Mass Spectrometry in Cancer Research
10.1016/bs.acr.2016.11.011
Spatial Quantitation of Drugs in tissues using Liquid Extraction Surface Analysis Mass Spectrometry Imaging
10.1038/srep37648
Correction to: Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging (Metabolomics, (2019), 15, 5, (68), 10.1007/s11306-019-1531-4)
10.1007/s11306-019-1540-3
Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs
10.1158/1078-0432.ccr-19-1871
Evaluation of UV-C Decontamination of Clinical Tissue Sections for Spatially Resolved Analysis by Mass Spectrometry Imaging (MSI)
10.1021/acs.analchem.0c03430
Deep Learning-Based Annotation Transfer between Molecular Imaging Modalities: An Automated Workflow for Multimodal Data Integration
10.1021/acs.analchem.0c02726
Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry
10.1021/acs.analchem.0c03908
Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging
10.1038/s41596-021-00538-w
Saverio Tardito
Tardito Saverio
ORCID: 0000-0002-5294-8683
Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes.
10.1016/j.jinorgbio.2005.04.017
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.
10.1016/j.ccell.2014.12.002
Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts.
10.1038/bjc.2014.425
Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification.
10.1016/j.stem.2014.06.002
Polyphenon E(R), a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis.
10.1093/carcin/bgt481
Copper-dependent cytotoxicity of 8-hydroxyquinoline derivatives correlates with their hydrophobicity and does not require caspase activation.
10.1021/jm301053a
HIF-independent role of prolyl hydroxylases in the cellular response to amino acids.
10.1038/onc.2012.465
Glutamine stimulates mTORC1 independent of the cell content of essential amino acids.
10.1007/s00726-012-1312-0
Expanding targets for a metabolic therapy of cancer: L-asparaginase.
10.2174/157489212798358001
L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells.
10.2174/156800911797264725
The non-proteinogenic amino acids L-methionine sulfoximine and DL-phosphinothricin activate mTOR.
10.1007/s00726-011-0981-4
Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells.
10.1021/ja109413c
Platelet gel in the treatment of cutaneous ulcers: the experience of the Immunohaematology and Transfusion Centre of Parma.
10.2450/2009.0118-09
The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells.
10.1074/jbc.M109.026583
TOE1 interacts with p53 to modulate its transactivation potential.
10.1016/j.febslet.2009.06.004
Synthesis, structural characterisation and solution chemistry of ruthenium(III) triazole-thiadiazine complexes.
10.1039/b823271g
Copper compounds in anticancer strategies.
10.2174/092986709787846532
Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells.
10.1021/jm061174f
The inhibition of glutamine synthetase sensitizes human sarcoma cells to L-asparaginase.
10.1007/s00280-007-0421-z
Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells.
10.1007/s00418-006-0183-4
Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.
10.15252/emmm.201707729
Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells.
10.1038/nm.4399
Cancer metabolism at a glance.
10.1242/jcs.181016
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
10.1038/ncb3272
Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth
10.3390/ijms19041099
Improving the metabolic fidelity of cancer models with a physiological cell culture medium
10.1126/sciadv.aau7314
Cell Culture Medium Formulation and Its Implications in Cancer Metabolism
10.1016/j.trecan.2019.05.004
Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells
10.1038/s42255-019-0084-1
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
10.1126/sciadv.aax6328
Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer
10.1158/0008-5472.can-19-1684
A map of the altered glioma metabolism
10.1016/j.molmed.2021.07.011
Julia Edgar
Edgar Julia
ORCID: 0000-0002-3869-0962
A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination
10.1038/nn.4425
An in vitro model for studying CNS white matter: functional properties and experimental approaches [version 1; referees: 2 approved]
10.12688/f1000research.16802.1
The Axon-Myelin Unit in Development and Degenerative Disease
10.3389/fnins.2018.00467
Reduced axonal diameter of peripheral nerve fibers in a mouse model of Rett syndrome
10.1016/j.neuroscience.2017.06.061
Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected
10.1186/s40478-017-0450-8
Dietary cholesterol promotes repair of demyelinated lesions in the adult brain
10.1038/ncomms14241
Time-Lapse Imaging of Glial-Axonal Interactions
10.1002/0471142301.ns0223s72
Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9
10.1093/brain/awv102
In vivo labeling of peroxisomes by photoconvertible mEos2 in myelinating glia of mice
10.1016/j.biochi.2013.10.022
Progesterone Antagonist Therapy in a Pelizaeus-Merzbacher Mouse Model
10.1016/j.ajhg.2014.03.001
Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2
10.1002/glia.22561
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity
10.1038/nature11007
Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue
10.1016/j.cell.2013.11.044
Interactions among mitochondrial proteins altered in glioblastoma
10.1007/s11060-014-1430-5
Neuronal Expression of GalNAc Transferase Is Sufficient to Prevent the Age-Related Neurodegenerative Phenotype of Complex Ganglioside-Deficient Mice
10.1523/jneurosci.3996-13.2014
Time-Lapse Imaging of the Dynamics of CNS Glial-Axonal Interactions In Vitro and Ex Vivo
10.1371/journal.pone.0030775
High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus-Merzbacher disease: comparison with quantitative measures of white matter pathology
10.1002/nbm.1700
Axon-glial interaction in the CNS: what we have learned from mouse models of Pelizaeus-Merzbacher disease
10.1111/j.1469-7580.2011.01363.x
PLP/DM20 Expression and turnover in a transgenic mouse model of pelizaeus-merzbacher disease
10.1002/glia.21043
Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus‐Merzbacher disease
10.1002/emmm.200900057
The role of CNS glia in preserving axon function
10.1016/j.conb.2009.08.003
Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression ofCnp1
10.1002/glia.20893
Distribution of mitochondria along small‐diameter myelinated central nervous system axons
10.1002/jnr.21672
PLP overexpression perturbs myelin protein composition and myelination in a mouse model of Pelizaeus-Merzbacher disease.
10.1002/glia.20465
Murine spinal cord explants: a model for evaluating axonal growth and myelination in vitro.
10.1002/jnr.21084
Genetic background influences UPR but not PLP processing in the rumpshaker model of PMD/SPG2.
10.1007/s11064-006-9122-y
Alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-mediated excitotoxic axonal damage is attenuated in the absence of myelin proteolipid protein.
10.1002/jnr.20859
Processing of PLP in a model of Pelizaeus-Merzbacher disease/SPG2 due to the rumpshaker mutation.
10.1002/glia.20325
Characterization of the murine splice variant Mobp155: developmental CNS expression pattern and subcellular localization of epitope-tagged protein.
10.1002/glia.20155
Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia.
10.1083/jcb.200312012
The myelinated axon is dependent on the myelinating cell for support and maintenance: molecules involved.
10.1002/jnr.20063
Age-related axonal and myelin changes in the rumpshaker mutation of the Plp gene.
10.1007/s00401-003-0808-9
Phenotypic analysis of mice deficient in the major myelin protein MOBP, and evidence for a novel Mobp isoform.
10.1002/glia.10103
Survival of, and competition between, oligodendrocytes expressing different alleles of the Plp gene.
10.1083/jcb.200202124
The proteolipid protein gene and myelin disorders in man and animal models.
10.1093/hmg/9.6.987
The fates of cells generated at the end of neurogenesis in developing mouse cortex.
10.1002/neu.1056
Radial migration in the cerebral cortex is enhanced by signals from thalamus.
10.1046/j.0953-816x.2001.01554.x
Transmission Electron Microscopy and Morphometry of the CNS White Matter
10.1007/978-1-0716-0585-1_18
Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication
10.1126/sciadv.aax6328
Neural stem cells restore myelin in a demyelinating model of Pelizaeus-Merzbacher disease
10.1093/brain/awaa080