Severe Acute Respiratory Syndrome–Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research
Philip A. Verhoef Sujatha Kannan Jamie L. Sturgill Elizabeth W. Tucker Peter E. Morris Andrew C. Miller Travis R. Sexton Jay L. Koyner Rana Hejal Scott C. Brakenridge Lyle L. Moldawer Richard S. Hotchkiss Teresa M. Blood Monty B. Mazer Scott Bolesta Sheila A. Alexander Donna Lee Armaignac Steven L. Shein Christopher Jones Caroline D. Hoemann Allan Doctor Stuart H. Friess Robert I. Parker Alexandre T. Rotta Kenneth E. Remy
Critical Care Explorations, 2021-3-12
https://doi.org/10.1097/CCE.0000000000000374
Andrew Miller
Miller Andrew
ORCID: 0000-0001-8474-5090
Early immunologic responses to trauma in the emergency department patients with major injuries 10.1016/j.resuscitation.2008.09.012
Disasters and women's health: Reflections from the 2010 earthquake in Haiti 10.1017/S1049023X12001677
Pulmonary complications of sickle cell disease 10.1164/rccm.201111-2082CI
Predictive models for tuberculous pleural effusions in a high tuberculosis prevalence region 10.1007/s00408-011-9342-z
Use of Probiotics for Treatment of Chemotherapy-induced Diarrhea: Is It a Myth? 10.1177/0148607109336596
Inhaled anticoagulation regimens for the treatment of smoke inhalation-associated acute lung injury: A systematic review 10.1097/CCM.0b013e3182a645e5
Silver sulfadiazine for the treatment of partial-thickness burns and venous stasis ulcers 10.1016/j.jaad.2010.06.014
Brain death and islam: The interface of religion, culture, history, law, and modern medicine 10.1378/chest.14-0130
A novel presentation of a rare chromosome 21q22.2 deletion 10.1097/MCD.0b013e3283157dc6
Influenza A 2009 (H1N1) virus in admitted and critically III patients 10.1177/0885066610393626
Three episodes of acquired pure red cell aplasia restricted to pregnancy 10.1515/JPM.2008.041
Novel influenza A(H1N1) virus among gravid admissions 10.1001/archinternmed.2010.126
Influence of nebulized unfractionated heparin and N-acetylcysteine in acute lung injury after smoke inhalation injury 10.1097/BCR.0b013e318198a268
Malignant mesothelioma and central nervous system metastases: Report of two cases, pooled analysis, and systematic review 10.1513/AnnalsATS.201404-165BC
Opinions on the Legitimacy of Brain Death Among Sunni and Shi’a Scholars 10.1007/s10943-015-0157-8
Secondary Syphilis 10.1016/j.jemermed.2007.02.048
Proptosis and painless loss of vision: A rare case of CD20+ orbital T-cell lymphoma 10.3129/i09-272
Chronic diseases and natural hazards: Impact of disasters on diabetic, renal, and cardiac patients 10.1017/S1049023X00005835
Fever of unknown origin and isolated noncaseating granuloma of the marrow: Could this be sarcoidosis? 10.2500/aap.2007.28.2982
Disasters, women's health, and conservative society: Working in pakistan with the turkish red crescent following the south asian earthquake 10.1017/S1049023X00004842
Does the current definition of contrast-induced acute kidney injury reflect a true clinical entity? 10.1111/acem.12011
Jundi-Shapur, bimaristans, and the rise of academic medical centres 10.1258/jrsm.99.12.615
A systematic review and pooled analysis of CPR-associated cardiovascular and thoracic injuries 10.1016/j.resuscitation.2014.01.028
Chronic rhinosinusitis and psoriasis: Do mutually exclusive systemic Th1 and Th2 disease patterns exist? 10.1080/00016480601002054
Major cancer regressions in mesothelioma after treatment with an anti-mesothelin immunotoxin and immune suppression 10.1126/scitranslmed.3006941
Immune enteral nutrition can improve outcomes in medical-surgical patients with ARDS: A prospective randomized controlled trial. 10.4172/jndt.1000109
Obesity, Anemia, and Cardiovascular Risk in Patients with Chronic Kidney Disease: Overview and Pathophysiologic Insights. 10.1007/s12170-009-0018-7
Cardiac rehabilitation using the Family-Centered Empowerment Model versus home-based cardiac rehabilitation in patients with myocardial infarction: a randomised controlled trial 10.1136/openhrt-2015-000349
Experimental assessment and future applications of the shikani tracheostomy speaking valve 10.1044/2015_AJSLP-14-0115
Effect of the Cardio First Angel™ device on CPR indices: A randomized controlled clinical trial 10.1186/s13054-016-1296-3
Nebulized heparin for patients under mechanical ventilation: an individual patient data meta-analysis 10.1186/s13613-016-0138-4
Epidemiology of Smoke Inhalation-associated Acute Lung Injury: Predictors of Mortality from 68 hospitals in the United States. 10.1016/j.chest.2016.06.008
Impact of the Affordable Care Act Medicaid expansion on emergency department high utilizers with ambulatory care sensitive conditions: A cross-sectional study 10.1016/j.ajem.2017.01.014
High-Frequency Ventilation Modalities as Salvage Therapy for Smoke Inhalation-Associated Acute Lung Injury 10.1177/0885066617714770
Effects of Stress on Critical Care Nurses: A National Cross-Sectional Survey. 10.1177/0885066617696853
Post-ICU Psychological Morbidity in Patients with ARDS and Delirium 10.1016/j.jcrc.2017.08.034
A Comprehensive Framework for International Medical Programs: A Consensus Statement from the American College of Academic International Medicine. 10.4103/IJAM.IJAM_88_17
The American College of Academic International Medicine 2017 Consensus Statement on International Medical Programs: Establishing a System of Objective Valuation and Quantitative Metrics to Facilitate the Recognition and Incorporation of Academic International Medical Efforts into Existing Promotion and Tenure Paradigms. 10.4103/IJAM.IJAM_84_17
A Comprehensive Framework for International Medical Programs: A Consensus Statement from the American College of Academic International Medicine. 10.4103/IJCIIS.IJCIIS_65_17
The american college of academic international medicine 2017 consensus statement on international medical programs: Establishing a system of objective valuation and quantitative metrics to facilitate the recognition and incorporation of academic international medical efforts into existing promotion and tenure paradigms 10.4103/IJCIIS.IJCIIS_64_17
Spiritual Health and Outcomes in Muslim ICU Patients: A National Structural Equation Modeling Study 10.1007/s10943-017-0543-5
10 Minute ENT Clinical Consult 10.1016/j.annemergmed.2009.12.003
Coadministration of Probiotics With Prescribed Antibiotics for Preventing Clostridium difficile Diarrhea 10.1111/acem.13557
Antivirals With Corticosteroids for the Treatment of Acute Bell's Palsy 10.1111/acem.13563
Single Maintenance and Reliever Therapy ( SMART ) Regimen for Management of Persistent Asthma 10.1111/acem.13659
Neuroleptanalgesia for acute abdominal pain: a systematic review 10.2147/JPR.S187798
Impact of Religiosity on Delirium Severity Among Critically Ill Shi’a Muslims: A Prospective Multi-Center Observational Study 10.1007/s10943-019-00895-7
Impact of United States political sanctions on international collaborations and research in Iran 10.1136/bmjgh-2019-001692
Intravenous Magnesium Sulfate to Treat Acute Headaches in the Emergency Department: A Systematic Review 10.1111/head.13648
Real-time compression feedback for patients with in-hospital cardiac arrest: a multi-center randomized controlled clinical trial 10.1186/s40560-019-0357-5
United States federal government regulation of international research collaborations: What every physician-scientist should know 10.4103/ijciis.ijciis_63_18
A rapid shallow breathing index threshold of 85 best predicts extubation success in chronic obstructive pulmonary disease patients with hypercapnic respiratory failure 10.21037/jtd.2019.03.103
Infection prevention for open fractures: Is antibiotic monotherapy equivalent to multitherapy? 10.4103/ijciis.ijciis_79_19
Opinions on the Legitimacy of Death Declaration by Neurological Criteria from the Perspective of 3 Abrahamic Faiths 10.5222/mmj.2019.48379
The "T" in trauma: the helper T-cell response and the role of immunomodulation in trauma and burn patients. 10.1097/TA.0b013e31815b839e
Preparing for and responding to mass casualties and disasters. 10.1001/virtualmentor.2010.12.9.fred1-1009
Mandated influenza vaccines and health care workers' autonomy. 10.1001/virtualmentor.2010.12.9.ccas2-1009
A comparison of commercially available compression feedback devices in novice and experienced healthcare practitioners: A prospective randomized simulation study 10.1002/mds3.10020
Comparison of non-invasive to invasive oxygenation ratios for diagnosing acute respiratory distress syndrome following coronary artery bypass graft surgery: a prospective derivation-validation cohort study. 10.1186/s13019-018-0804-8
What's new in critical illness and injury science? Utility of central venous oxygen saturation to risk stratify septic patients 10.4103/ijciis.ijciis_100_19
What's new in Academic International Medicine? Highlighting the need for establishing a national accreditation system for International Medical Programs 10.4103/ijam.ijam_68_19
The Fourth Annual Academic International Medicine Congress (AIM 2019) in Philadelphia, Pennsylvania, July 26–28, 2019: Advancing Global Leadership to Promote Health Equity 10.4103/ijam.ijam_61_19
Natural versus artificial light exposure on delirium incidence in ARDS patients 10.1186/s13613-020-0630-8
Magnesium’s Analgesic Effects are Independent of Serum Concentration 10.1111/head.13763
Immune Enteral Nutrition Can Improve Outcomes in Medical-Surgical Patients with ARDS: A Prospective Randomized Controlled Trial 10.4172/2161-0509.1000109
Paracetamol for low back pain 10.1002/14651858.CD012230
Ethical Issues Confronting Muslim Patients in Perioperative and Critical Care Environments 10.1016/j.anclin.2020.01.002
Pregnancy Outcomes of Wives of Chemical and Non-Chemical Weapons Exposed Veterans in Ahvaz, Iran: A Retrospective Cohort Study 10.1017/S1049023X2000076X
The Shikani HME: A New Tracheostomy Heat and Moisture Exchanger 10.1044/2020_JSLHR-19-00107
Clarification on Islamic Jurisprudence and Transplantation. 10.1097/txd.0000000000001022
The 2019-2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint American College of Academic International Medicine-World Academic Council of Emergency Medicine Multidisciplinary COVID-19 Working Group Consensus Paper 10.4103/JGID.JGID_86_20
Squeale of Corticosteroids (CS) Therapy in Intensive Care Unit Patients 10.1164/AJRCCM-CONFERENCE.2010.181.1_MEETINGABSTRACTS.A6133
Clinical & Economic Impacts Of Corticosteroids Therapy In The Intensive Care Unit Patients 10.1164/AJRCCM-CONFERENCE.2011.183.1_MEETINGABSTRACTS.A1676
Pediatric Patients With 2009 H1N1 Did Not Differ Significantly From A 2005-2008 Seasonal Cohort In A New York City Teaching Hospital 10.1164/AJRCCM-CONFERENCE.2011.183.1_MEETINGABSTRACTS.A4151
Real-time audiovisual feedback during CPR: A clarification, meta-analysis update, and caution for interpretation 10.1016/j.resuscitation.2020.09.043
COVID-19 blind spots: A consensus statement on the importance of competent political leadership and the need for public health cognizance 10.4103/jgid.jgid_397_20
Real-time audio-visual feedback with handheld nonautomated external defibrillator devices during cardiopulmonary resuscitation for in-hospital cardiac arrest: A meta-analysis 10.4103/ijciis.ijciis_155_20
Severe Acute Respiratory Syndrome–Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research 10.1097/CCE.0000000000000374
Growth through adversity: The impact of COVID-19 pandemic on the american college of academic international medicine 10.4103/IJAM.IJAM_162_20
What's new in Academic International Medicine? International health security agenda - Expanded and re-defined 10.4103/IJAM.IJAM_113_20
A comparison of diagnostic algorithms and clinical parameters to diagnose ventilator-associated pneumonia: a prospective observational study 10.1186/s12890-021-01527-1
Scott Brakenridge
Brakenridge Scott
ORCID: 0000-0002-7327-3718
Emergent laparotomy and temporary abdominal closure for the cirrhotic patient 10.1016/j.jss.2016.11.013
Predicting appendiceal tumors among patients with appendicitis. 10.1097/ta.0000000000001378
Antibiotics May be Safely Discontinued Within One Week of Percutaneous Cholecystostomy 10.1007/s00268-016-3861-y
Acute Kidney Injury Following Exploratory Laparotomy and Temporary Abdominal Closure. 10.1097/shk.0000000000000825
Routine surveillance cholangiography after percutaneous cholecystostomy delays drain removal and cholecystectomy. 10.1097/ta.0000000000001315
Temporary abdominal closure for trauma and intra-abdominal sepsis: Different patients, different outcomes. 10.1097/ta.0000000000001283
Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome. 10.1097/ccm.0000000000002074
The long-term burden of severe sepsis and septic shock: Sepsis recidivism and organ dysfunction. 10.1097/ta.0000000000001135
Sex-based differences in the genomic response, innate immunity, organ dysfunction, and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock. 10.1097/ta.0000000000001113
Multicenter external validation of the Geriatric Trauma Outcome Score: A study by the Prognostic Assessment of Life and Limitations After Trauma in the Elderly (PALLIATE) consortium. 10.1097/ta.0000000000000926
Patterns of gene expression among murine models of hemorrhagic shock/trauma and sepsis 10.1152/physiolgenomics.00072.2015
A detailed characterization of the dysfunctional immunity and abnormal myelopoiesis induced by severe shock and trauma in the aged 10.4049/jimmunol.1500984
Successful implementation of a packed red blood cell and fresh frozen plasma transfusion protocol in the surgical intensive care unit 10.1371/journal.pone.0126895
Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock 10.1186/s13054-015-0788-x
Evaluation and management of blunt traumatic aortic injury: a practice management guideline from the Eastern Association for the Surgery of Trauma. 10.1097/jtn.0000000000000118
Evaluation and management of blunt traumatic aortic injury: a practice management guideline from the Eastern Association for the Surgery of Trauma. 10.1097/ta.0000000000000470
A protocol for the management of adhesive small bowel obstruction. 10.1097/ta.0000000000000491
Variability is the standard: the management of venous thromboembolic disease following trauma. 10.1097/ta.0b013e3182aa2fa9
Comparing clinical predictors of deep venous thrombosis versus pulmonary embolus after severe injury: a new paradigm for posttraumatic venous thromboembolism? 10.1097/ta.0b013e31828cc9a0
Limb salvage after complex repairs of extremity arterial injuries is independent of surgical specialty training. 10.1097/ta.0b013e3182827035
A randomized, double-blinded, placebo-controlled pilot trial of anticoagulation in low-risk traumatic brain injury: The Delayed Versus Early Enoxaparin Prophylaxis I (DEEP I) study. 10.1097/ta.0b013e31825ac49e
Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury. 10.1097/ta.0b013e318224d328
Predictors of early versus late timing of pulmonary embolus after traumatic injury 10.1016/j.amjsurg.2009.12.005
Boerhaave syndrome presenting as massive hemothorax. 10.1097/smj.0b013e318186be00
High-frequency percussive ventilation improves oxygenation in trauma patients with acute respiratory distress syndrome: a retrospective review 10.1016/j.amjsurg.2006.01.021
Detection of intra-abdominal injury using diagnostic peritoneal lavage after shotgun wound to the abdomen. 10.1097/01.ta.0000037292.17482.69
Prospective evaluation of the sensitivity of physical examination in chest trauma 10.1097/00005373-200212000-00017
Persistent injury-associated anemia in aged rats 10.1016/j.exger.2018.01.001
Occult bowel injury after blunt abdominal trauma 10.1016/j.amjsurg.2018.11.018
Immune Checkpoint Inhibition in Sepsis 10.1097/ccm.0000000000003685
Persistently Elevated Glucagon-Like Peptide-1 Levels among Critically Ill Surgical Patients after Sepsis and Development of Chronic Critical Illness and Dismal Long-Term Outcomes 10.1016/j.jamcollsurg.2019.04.014
The Development of Chronic Critical Illness Determines Physical Function, Quality of Life, and Long-Term Survival Among Early Survivors of Sepsis in Surgical ICUs. 10.1097/ccm.0000000000003655
Cardiac pseudoaneurysm following non-operative management after penetrating thoracoabdominal trauma and pericardial window 10.1097/ta.0000000000002189
The impact of standardized protocol implementation for surgical damage control and temporary abdominal closure after emergent laparotomy 10.1097/ta.0000000000002170
Persistent inflammation and anemia among critically ill septic patients 10.1097/ta.0000000000002147
The Impact of Prior Laparotomy and Intra-abdominal Adhesions on Bowel and Mesenteric Injury Following Blunt Abdominal Trauma 10.1007/s00268-018-4792-6
Prospective Validation of a Transcriptomic Metric in Severe Trauma 10.1097/sla.0000000000003204
Trauma Surgeon and Palliative Care Physician Attitudes Regarding Goals-of-Care Delineation for Injured Geriatric Patients 10.1177/1049909118823182
Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults 10.1371/journal.pone.0205327
Burn Surgeon and Palliative Care Physician Attitudes Regarding Goals of Care Delineation for Burned Geriatric Patients 10.1093/jbcr/iry027
Anemia and blood transfusion in elderly trauma patients 10.1016/j.jss.2018.04.021
The Postinjury Inflammatory State and the Bone Marrow Response to Anemia. 10.1164/rccm.201712-2536oc
The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients. 10.1097/ta.0000000000001921
Effect of Time to Operation on Value of Care in Acute Care Surgery 10.1007/s00268-018-4476-2
Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome. 10.3389/fimmu.2018.01511
The effects of beta blockade and clonidine on persistent injury-associated anemia 10.1016/j.jss.2018.06.001
Variations in institutional review board processes and consent requirements for trauma research: An EAST multicenter survey 10.1136/tsaco-2018-000176
Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery 10.1016/j.surg.2018.04.011
Resuscitative Endovascular Balloon Occlusion of the Aorta: Implementation and Preliminary Results at an Academic Level I Trauma Center 10.1016/j.jamcollsurg.2018.03.042
Innate immunity in the persistent inflammation, immunosuppression, and catabolism syndrome and its implications for therapy 10.3389/fimmu.2018.00595
Activity and circadian rhythm of sepsis patients in the Intensive Care Unit 10.1109/BHI.2018.8333359
Persistent injury-associated anemia and aging: Novel insights 10.1097/TA.0000000000001766
Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis 10.1097/SHK.0000000000000981
A protocol for non-operative management of uncomplicated appendicitis 10.1097/TA.0000000000001709
Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients 10.1097/TA.0000000000001758
Hypertonic saline resuscitation after emergent laparotomy and temporary abdominal closure 10.1097/TA.0000000000001730
Chronic Critical Illness: Application of What We Know 10.1002/ncp.10024
The epidemiology of chronic critical illness after severe traumatic injury at two level-one trauma centers 10.1097/CCM.0000000000002697
Successful nonoperative management of uncomplicated appendicitis: predictors and outcomes 10.1016/j.jss.2017.10.006
Characterization of hypoalbuminemia following temporary abdominal closure 10.1097/TA.0000000000001553
Validation of a Geriatric Trauma Prognosis Calculator: A P.A.L.Li.A.T.E. Consortium Study 10.1111/jgs.15009
Sepsis and Critical Illness Research Center investigators: Protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients 10.1136/bmjopen-2016-015136
The effects of red cell transfusion donor age on nosocomial infection among trauma patients 10.1016/j.amjsurg.2017.07.004
The authors reply 10.1097/CCM.0000000000002469
Computed tomography evidence of fluid in the hernia sac predicts surgical site infection following mesh repair of acutely incarcerated ventral and groin hernias 10.1097/TA.0000000000001503
A comparison of prognosis calculators for geriatric trauma: A Prognostic Assessment of Life and Limitations After Trauma in the Elderly consortium study. 10.1097/ta.0000000000001506
Persistent Inflammation, Immunosuppression and Catabolism Syndrome 10.1016/j.ccc.2016.12.001
Early bronchoalveolar lavage for intubated trauma patients with TBI or chest trauma 10.1016/j.jcrc.2017.02.010
Neural network prediction of severe lower intestinal bleeding and the need for surgical intervention 10.1016/j.jss.2016.12.032
Nutritional Assessment, Parenteral, and Enteral Nutrition 10.1016/B978-0-323-47873-1.00009-7
Intubated Trauma Patients Receiving Prolonged Antibiotics for Pneumonia despite Negative Cultures: Predictors and Outcomes 10.1089/sur.2016.108
Changes in massive transfusion over time: An early shift in the right direction? 10.1097/TA.0b013e3182410a3c
Human myeloid-derived suppressor cells are associated with chronic immune suppression after severe sepsis/septic shock 10.1097/SLA.0000000000001783
DC-SIGN, but not sDC-SIGN, can modulate IL-2 production from PMA- and anti-CD3-stimulated primary human CD4 T cells 10.1093/intimm/dxh258
LETTERS TO the EDITOR 10.1097/00005373-200306000-00047
Improved outcomes following implementation of an acute gastrointestinal bleeding multidisciplinary protocol 10.1097/TA.0000000000001295
Editorial critique 10.1097/TA.0000000000000996
Pathophysiology and Treatment Strategies of Acute Myopathy and Muscle Wasting after Sepsis 10.3390/jcm10091874
Chronic Critical Illness Elicits a Unique Circulating Leukocyte Transcriptome in Sepsis Survivors 10.3390/jcm10153211
Association of Postoperative Clinical Outcomes With Sarcopenia, Frailty, and Nutritional Status in Older Patients With Colorectal Cancer: Protocol for a Prospective Cohort Study (Preprint) 10.2196/preprints.16846
Association of Postoperative Clinical Outcomes With Sarcopenia, Frailty, and Nutritional Status in Older Patients With Colorectal Cancer: Protocol for a Prospective Cohort Study 10.2196/16846
Resolution of organ dysfunction as a predictor of long-term survival in necrotizing soft tissue infections: Analysis of the AB103 Clinical Composite Endpoint Study in Necrotizing Soft Tissue Infections trial and a retrospective claims database-linked chart study 10.1097/ta.0000000000003183
Biomarker Evidence of the Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS) in Chronic Critical Illness (CCI) after Surgical Sepsis 10.1097/sla.0000000000005067
Identification of Unique microRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells after Hemorrhagic Shock and Polytrauma in Young and Old Adult Mice 10.1097/ta.0000000000003350
Chronic critical illness after hypothermia in trauma patients 10.1136/tsaco-2021-000747
Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report 10.1097/cce.0000000000000500
The impact of sarcopenia and acute muscle mass loss on long‐term outcomes in critically ill patients with intra‐abdominal sepsis 10.1002/jcsm.12752
Transcriptomic Changes Within Human Bone Marrow After Severe Trauma 10.1097/shk.0000000000001826
In Vitro–Administered Dexamethasone Suppresses T Cell Function With Reversal by Interleukin-7 in Coronavirus Disease 2019 10.1097/cce.0000000000000378
Older Adults Demonstrate Biomarker Evidence of the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PICS) After Sepsis 10.1093/gerona/glab080
Severe Acute Respiratory Syndrome–Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research 10.1097/cce.0000000000000374
Immunological Endotyping of Chronic Critical Illness After Severe Sepsis 10.3389/fmed.2020.616694
The Effect of Aging Physiology on Critical Care 10.1016/j.ccc.2020.08.006
Older Sepsis Survivors Suffer Persistent Disability Burden and Poor Long-Term Survival 10.1093/geroni/igaa057.454
Abdominal sepsis patients have a high incidence of chronic critical illness with dismal long-term outcomes 10.1016/j.amjsurg.2020.07.016
A Whole Blood Enzyme-Linked Immunospot Assay for Functional Immune Endotyping of Septic Patients 10.4049/jimmunol.2001088
Audiovisual Modules to Enhance Informed Consent in the ICU: A Pilot Study 10.1097/cce.0000000000000278
Distinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock 10.1097/ta.0000000000003029
Clinical Trajectories of Acute Kidney Injury in Surgical Sepsis 10.1097/sla.0000000000004360
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis 10.1096/fj.202002150r
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study 10.1097/shk.0000000000001671
Immunotherapies for COVID-19: lessons learned from sepsis 10.1016/s2213-2600(20)30217-4
Discovery and Validation of Urinary Molecular Signature of Early Sepsis 10.1097/cce.0000000000000195
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections 10.1172/jci.insight.140329
What's New in Shock, September 2020? 10.1097/shk.0000000000001588
Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice 10.1097/shk.0000000000001648
Vitamin D status is associated with hepcidin and hemoglobin concentrations in patients with severe traumatic injury 10.1097/ta.0000000000002895
Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults 10.3389/fimmu.2020.01289
Enteral Nutrition Administration Record Prescribing Process Using Computerized Order Entry: A New Paradigm and Opportunities to Improve Outcomes in Critically Ill Patients 10.1002/jpen.1870
Evaluation and management of blunt cerebrovascular injury: A practice management guideline from the Eastern Association for the Surgery of Trauma 10.1097/ta.0000000000002668
Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study 10.1186/s13054-020-02917-3
Older Sepsis Survivors Suffer Persistent Disability Burden and Poor Long‐Term Survival 10.1111/jgs.16435
Persistently increased cell-free DNA concentrations only modestly contribute to outcome and host response in sepsis survivors with chronic critical illness 10.1016/j.surg.2019.11.018
Artificial Intelligence and Surgical Decision-making 10.1001/jamasurg.2019.4917
Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress 10.1097/shk.0000000000001506
22: CIRCULATING LEUKOCYTE TRANSCRIPTOMES IN CHRONIC CRITICAL ILLNESS VS. RAPID RECOVERY SEPSIS PATIENTS 10.1097/01.ccm.0000618588.59696.bf
1648: A UNIQUE LEUKOCYTE TRANSCRIPTOME IN CHRONIC CRITICAL ILLNESS PATIENTS WITH POOR LONG-TERM OUTCOMES 10.1097/01.ccm.0000648496.17876.1e
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis 10.1186/s13054-019-2628-x
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model* 10.1097/ccm.0000000000003926
Effect of β-Blockade on the Expression of Regulatory MicroRNAs after Severe Trauma and Chronic Stress 10.1016/j.jamcollsurg.2019.08.643
Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab 10.1007/s00134-019-05704-z
Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma 10.1038/s41598-019-50044-z
Current Epidemiology of Surgical Sepsis 10.1097/sla.0000000000003458
Delayed interhospital transfer of critically ill patients with surgical sepsis 10.1097/ta.0000000000002476
Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors 10.1186/s13054-019-2505-7
The authors reply 10.1097/ccm.0000000000003887
Kenneth Remy
Remy Kenneth
ORCID: 0000-0001-5222-9884
Is there immune suppression in the critically ill patient - pro? 10.1016/B978-0-323-64068-8.00041-9
Recommendations on RBC transfusion in general critically ill children based on hemoglobin and/or physiologic thresholds from the pediatric critical care transfusion and Anemia expertise initiative 10.1097/PCC.0000000000001590
Finding ways for children's doctors to care for big 'Kids' and save adults in a pandemic 10.1136/archdischild-2021-321628
Prolonged adaptive immune activation in COVID-19: Implications for maintenance of long-term immunity? 10.1172/JCI143928
Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm 10.1126/sciadv.abe3024
Transfusion of recently donated (fresh) red blood cells (RBCs) does not improve survival in comparison with current practice, while safety of the oldest stored units is yet to be established: a meta-analysis 10.1111/vox.12380
Haptoglobin therapy has differential effects depending on severity of canine septic shock and cell-free hemoglobin level 10.1111/trf.15567
High-flow nasal cannula may be no safer than non-invasive positive pressure ventilation for COVID-19 patients 10.1186/s13054-020-02892-9
Does bacillus anthracis lethal toxin directly depress myocardial function? A review of clinical cases and preclinical studies 10.3390/toxins7124891
Application of systems dynamics and group model building to identify barriers and facilitators to acute care delivery in a resource limited setting 10.1186/s12913-020-06014-7
The authors reply 10.1097/PCC.0000000000002517
Palliative Care-Led meetings for families of ICU patients [1] 10.1001/jama.2016.14316
To the editor 10.1056/NEJMc1508390
A whole blood enzyme-linked immunospot assay for functional immune endotyping of septic patients 10.4049/jimmunol.2001088
Restoration of T cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration 10.1371/journal.pone.0199497
Immunotherapies for COVID-19: lessons learned from sepsis 10.1016/S2213-2600(20)30217-4
Association of Interleukin 7 Immunotherapy with Lymphocyte Counts among Patients with Severe Coronavirus Disease 2019 (COVID-19) 10.1001/jamanetworkopen.2020.16485
Targeted immunosuppression distinguishes COVID-19 from influenza in moderate and severe disease 10.1101/2020.05.28.20115667
High-flow nasal cannula utilization in pediatric critical care 10.4187/respcare.05153
Mechanisms of red blood cell transfusion-related immunomodulation 10.1111/trf.14488
Role of granulocyte transfusions in invasive fusariosis: Systematic review and single-center experience 10.1111/trf.13099
An overview of investigational toxin-directed therapies for the adjunctive management of Bacillus anthracis infection and sepsis 10.1517/13543784.2015.1041587
In a canine pneumonia model of exchange transfusion, altering the age but not the volume of older red blood cells markedly alters outcome 10.1111/trf.13275
Haptoglobin improves shock, lung injury, and survival in canine pneumonia 10.1172/jci.insight.123013
Effects of platelet-sparing leukocyte reduction and agitation methods on in vitro measures of hemostatic function in cold-stored whole blood 10.1097/TA.0000000000001870
Transfused older stored red blood cells improve the clinical course and outcome in a canine lethal hemorrhage and reperfusion model 10.1111/trf.13213
Changes in Pediatric ICU Utilization and Clinical Trends During the Coronavirus Pandemic 10.1016/j.chest.2021.03.004
Red blood cell storage age – what we know from clinical trials 10.1080/17474086.2016.1243051
Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness 10.1111/trf.13855
Pediatric anti-N-methyl-d-aspartate receptor encephalitis: A review with pooled analysis and critical care emphasis 10.3389/fped.2017.00250
High-flow oxygen as noninvasive ventilation may complicate timely intubation in patients with acute respiratory distress syndrome 10.1097/CCM.0000000000001782
Consensus recommendations for rbc transfusion practice in critically Ill children from the pediatric critical care transfusion and Anemia expertise initiative 10.1097/PCC.0000000000001613
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections 10.1172/jci.insight.140329
Caring for Critically Ill Adults with Coronavirus Disease 2019 in a PICU: Recommendations by Dual Trained Intensivists∗ 10.1097/PCC.0000000000002429
IL-10 has differential effects on the innate and adaptive immune systems of septic patients 10.4049/jimmunol.1900637
The influence of the storage lesion(s) on pediatric red cell transfusion 10.1097/MOP.0000000000000224
Coronavirus Disease 2019: A Pandemic Spawning an Infodemic∗ 10.1097/PCC.0000000000002782
Sedation protocol for critically ill pediatric patients 10.1001/jama.2015.3459
A Peptide-Based Checkpoint Immunomodulator Alleviates Immune Dysfunction in Murine Polymicrobial Sepsis 10.1097/SHK.0000000000001682
Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report. 10.1097/cce.0000000000000500
IL-7 Immunotherapy in a Nonimmunocompromised Patient With Intractable Fungal Wound Sepsis. 10.1093/ofid/ofab256
In Vitro-Administered Dexamethasone Suppresses T Cell Function With Reversal by Interleukin-7 in Coronavirus Disease 2019. 10.1097/cce.0000000000000378
Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research. 10.1097/cce.0000000000000374
Dysregulation of the Leukocyte Signaling Landscape during Acute COVID-19 10.21203/rs.3.rs-244150/v1
Delayed Development of Coronary Artery Dilitation in Suspected Severe Acute Respiratory Syndrome Coronavirus 2 Multisystem Inflammatory Syndrome: More Research Needed. 10.1097/cce.0000000000000236
Pediatric Plasma and Platelet Transfusions on Extracorporeal Membrane Oxygenation: A Subgroup Analysis of Two Large International Point-Prevalence Studies and the Role of Local Guidelines. 10.1097/pcc.0000000000002160
Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial. 10.1001/jama.2019.17478
Implementation of the Recommendations for RBC Transfusions for Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001592
Recommendations on Selection and Processing of RBC Components for Pediatric Patients From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001625
Recommendations on the Indications for RBC Transfusion for the Critically Ill Child Receiving Support From Extracorporeal Membrane Oxygenation, Ventricular Assist, and Renal Replacement Therapy Devices From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001600
Recommendations on RBC Transfusion Support in Children With Hematologic and Oncologic Diagnoses From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001610
Recommendations on RBC Transfusion in Infants and Children With Acquired and Congenital Heart Disease From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001603
Recommendations on RBC Transfusion in Critically Ill Children With Acute Brain Injury From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001589
Recommendations on RBC Transfusion in Critically Ill Children With Nonlife-Threatening Bleeding or Hemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001605
Recommendations on RBC Transfusions for Critically Ill Children With Nonhemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001620
Recommendations on RBC Transfusions in Critically Ill Children With Acute Respiratory Failure From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 10.1097/pcc.0000000000001619
The Pediatric Critical Care Transfusion and Anemia Expertise Initiative Consensus Conference Methodology. 10.1097/pcc.0000000000001593
Successful Surgical Repair and Perioperative Management of 6-Month-Old With Total Anomalous Pulmonary Venous Return in a Developing Country: Considerations for the Treatment of Pulmonary Hypertension. 10.14740/cr651w
Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support. 10.1186/s40635-017-0159-9
Outcomes of vagal nerve stimulation in a pediatric population: a single center experience. 10.1016/j.seizure.2013.10.002
Age-related differences in emotional reactivity, regulation, and rejection sensitivity in adolescence. 10.1037/a0028297
A place at the table for children in the ebola virus disease discussion 10.1097/PCC.0000000000000368
Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia 10.1182/blood-2013-11-539353
Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia 10.1111/trf.12607
Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle 10.1152/ajplung.00068.2013
B. anthracis associated cardiovascular dysfunction and shock: The potential contribution of both non-toxin and toxin components 10.1186/1741-7015-11-217
B. anthracis edema toxin increases cAMP levels and inhibits phenylephrinestimulated contraction in a rat aortic ring model 10.1152/ajpheart.00185.2013
Cerebellar metastatic papillary thyroid carcinoma in a pediatric patient with complex congenital heart disease 10.1515/jpem-2012-0162
Physiologic Foundations of Cardiopulmonary Resuscitation 10.1016/B978-0-323-07307-3.10033-3
Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines. 10.1186/s40635-015-0043-4
Immunizations (Adult) 10.1007/978-0-387-33754-8_240
Faculty of 1000 evaluation for Ventilator-associated pneumonia in pediatric trauma patients. 10.3410/f.1162712.624295
Faculty of 1000 evaluation for Association between ICU admission during morning rounds and mortality. 10.3410/f.1704956.2142056
Enterococcus Pseudoavium Sepsis In A 50 Year Old Male With B Cell Lymphoma 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4597
Granuloycte Therapy As Treatment For Candida Parapsilosis Sepsis In An Aplastic Anemia Patient 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4600
Faculty of 1000 evaluation for The role of intestinal colonization with gram-negative bacteria as a source for intensive care unit-acquired bacteremia. 10.3410/f.10436956.11268054
Faculty of 1000 evaluation for Cold aortic flush and chest compressions enable good neurologic outcome after 15 mins of ventricular fibrillation in cardiac arrest in pigs. 10.3410/f.5278957.5220056
Faculty of 1000 evaluation for Early exercise in critically ill patients enhances short-term functional recovery. 10.3410/f.1354956.1186054
Faculty of 1000 evaluation for Infectious risk associated with arterial catheters compared with central venous catheters. 10.3410/f.3285957.2971055
Faculty of 1000 evaluation for Influence of vasopressor agent in septic shock mortality. Results from the Portuguese Community-Acquired Sepsis Study (SACiUCI study). 10.3410/f.1148122.618516
Novel Expression Of The TMEM16 Family Of Calcium Activated Chloride Channels In Human Airway Epithelium And Smooth Muscle Cells 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a6035
Summary of the Sussex-Huawei locomotion-transportation recognition challenge
Observation of a manifold in the chaotic phase space of an asymmetric optical microcavity
Localized temporal variation of Earth's inner-core boundary from high-quality waveform doublets
Off-axis multi-wavelength dispersion controlling metalens for multi-color imaging
Impact of United States political sanctions on international collaborations and research in Iran