CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly
Brandon E. Aubol Jacob M. Wozniak Laurent Fattet David J. Gonzalez Joseph A. Adams
Jacob Wozniak
Wozniak Jacob
ORCID: 0000-0002-2453-0861
Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function 10.1073/pnas.1917295117
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules 10.1016/j.cell.2017.12.032
American Gut: an Open Platform for Citizen Science Microbiome Research 10.1128/msystems.00031-18
Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Protein Vpr 10.1074/mcp.m116.066019
Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas 10.1016/j.cels.2018.04.010
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages 10.1016/j.foodchem.2019.125290
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry 10.1074/mcp.tir118.001099
Optimization of carbon and energy utilization through differential translational efficiency 10.1038/s41467-018-06993-6
EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells 10.1038/s41556-019-0330-5
Organ-level protein networks as a reference for the host effects of the microbiome 10.1101/gr.256875.119
Quantitative analysis of Mycobacterium avium subsp. hominissuis proteome in response to antibiotics and during exposure to different environmental conditions 10.1186/s12014-019-9260-2
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Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures 10.1016/j.cell.2020.07.040
CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly 10.1073/pnas.2018251118
Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption 10.1126/scisignal.abc1044
Laurent FATTET
FATTET Laurent
ORCID: 0000-0001-5152-4937
Molecular interactions connecting the function of the serine-arginine–rich protein SRSF1 to protein phosphatase 1 10.1074/jbc.RA118.004587
Apical–basal polarity inhibits epithelial–mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation 10.1038/s41556-019-0291-8
Molecular and Cellular Mechanobiology of Cancer 10.1007/978-1-4939-5617-3_13
Regulation of Breast Cancer Stem Cell by Tissue Rigidity 10.21236/ada621308
Regulation of Breast Cancer Stem Cell by Tissue Rigidity 10.21236/ada609393
Tissue Stiffness and Tumor Progression: The Dark Side of the Force 10.21770/0909-3004.001
94: TIF1γ SUMOylation in TGFβ signaling 10.1016/s0007-4551(15)31187-5
Mobilization of a splicing factor through a nuclear kinase–kinase complex 10.1042/bcj20170672
The forces behind EMT and tumor metastasis 10.1080/15384101.2015.1063296
Dynamically stiffening hydrogels differentially modulates malignant transformation of mammary epithelial cells 10.3389/conf.fbioe.2016.01.00438
Dynamic Regulation of Tgf-B Signaling by Tif1γ: A Computational Approach 10.1371/journal.pone.0033761
100: TIF1γ and Smad4 are antagonistic regulators of TGFβ dependent EMT 10.1016/s0007-4551(15)31193-0
Biomaterials to model and measure epithelial cancers 10.1038/s41578-018-0051-6
Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing 10.1016/j.molcel.2016.05.034
Redirecting SR Protein Nuclear Trafficking through an Allosteric Platform 10.1016/j.jmb.2017.05.022
The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition 10.1371/journal.pone.0139179
Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function 10.1042/bj20141373
Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells 10.1038/embor.2011.78
TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients 10.1186/s12885-015-1471-y
Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway 10.1038/ncb3157
RNA Helicases DDX5 and DDX17 Dynamically Orchestrate Transcription, miRNA, and Splicing Programs in Cell Differentiation 10.1016/j.celrep.2014.05.010
Abstract P4-11-24: TIF1[gamma] interacts with the TGFβ1/SMAD4 signaling leading to poorer outcome in operable breast cancer 10.1158/1538-7445.sabcs14-p4-11-24
Molecular Pathways: Linking Tumor Microenvironment to Epithelial-Mesenchymal Transition in Metastasis 10.1158/1078-0432.ccr-13-3173
Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser–Arg protein substrate 10.1074/jbc.RA119.008463
Nuclear protein kinase CLK1 uses a non-Traditional docking mechanism to select physiological substrates 10.1042/BJ20150903
TIF1γ requires sumoylation to exert its repressive activity on TGFβ signaling 10.1242/jcs.126748
Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition 10.1242/dev.085068
Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling 10.1073/pnas.1814204116
Combination of a discovery LC-MS/MS analysis and a label-free quantification for the characterization of an epithelial-mesenchymal transition signature 10.1016/j.jprot.2014.05.026
CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly 10.1073/pnas.2018251118
Netrin-4 regulates stiffness and metastasis 10.1038/s41563-021-01012-4
David Gonzalez
Gonzalez David
ORCID: 0000-0003-1423-5970
Identification of a Human Skin Commensal Bacterium that Selectively Kills Cutibacterium acnes 10.1016/j.jid.2019.12.026
Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic 10.1128/mSystems.00340-20
CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly 10.1073/pnas.2018251118