A community resource for paired genomic and metabolomic data mining
Schorn MA Verhoeven S Ridder L Huber F Acharya DD Aksenov AA Aleti G Moghaddam JA Aron AT Aziz S Bauermeister A Bauman KD Baunach M van der Hooft JJJ
Neha Garg
Garg Neha
ORCID: 0000-0002-2760-7123
Creating a 3D microbial and chemical snapshot of a human habitat 10.1038/s41598-018-21541-4
Dereplication of peptidic natural products through database search of mass spectra 10.1038/nchembio.2219
Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae 10.7554/eLife.24214
Metabolic Fingerprints from the Human Oral Microbiome Reveal a Vast Knowledge Gap of Secreted Small Peptidic Molecules 10.1128/mSystems.00058-17
Multi-omics Analysis of Periodontal Pocket Microbial Communities Pre- and Posttreatment 10.1128/mSystems.00016-17
Natural products as mediators of disease 10.1039/c6np00063k
Three-Dimensional Microbiome and Metabolome Cartography of a Diseased Human Lung 10.1016/j.chom.2017.10.001
Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis 10.1021/acschembio.6b01031
Characterization of the Stereochemical Configuration of Lanthionines Formed by the Lanthipeptide Synthetase GeoM 10.1002/bip.22876
Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats 10.1021/acs.analchem.6b03456
Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome 10.1038/ismej.2015.207
Microbiome-wide association studies link dynamic microbial consortia to disease 10.1038/nature18850
Spatial Molecular Architecture of the Microbial Community of a Peltigera Lichen 10.1128/mSystems.00139-16
Chemoenzymatic Synthesis of Acyl Coenzyme A Substrates Enables in Situ Labeling of Small Molecules and Proteins 10.1021/acs.orglett.5b02113
Mass spectral similarity for untargeted metabolomics data analysis of complex mixtures 10.1016/j.ijms.2014.06.005
Chemical Rescue and Inhibition Studies to Determine the Role of Arg301 in Phosphite Dehydrogenase 10.1371/journal.pone.0087134
Mass spectrometry of natural products: current, emerging and future technologies 10.1039/c4np00044g
Mode of action and structure-activity relationship studies of geobacillin I 10.1038/ja.2013.112
Specialized Metabolites from the Microbiome in Health and Disease 10.1016/j.cmet.2014.10.016
Substrate Specificity of the Lanthipeptide Peptidase ElxP and the Oxidoreductase ElxO 10.1021/cb5002526
The Intestinal Metabolome: An Intersection Between Microbiota and Host 10.1053/j.gastro.2014.03.001
In vitro activity of the nisin dehydratase NisB 10.1073/pnas.1222488110
Cloning, sequence analysis, expression of Cyathus bulleri laccase in Pichia pastoris and characterization of recombinant laccase 10.1186/1472-6750-12-75
Lantibiotics from Geobacillus thermodenitrificans 10.1073/pnas.1116815109
Production of Lantipeptides in Escherichia coli 10.1021/ja109044r
Mass Spectrometry-Based Integration and Expansion of the Chemical Diversity Harbored Within a Marine Sponge. 10.1007/s13361-019-02207-5
The chemical topology of a bacterial swarm. 10.1074/jbc.H118.003178
Chemoenzymatic Synthesis of Starting Materials and Characterization of Halogenases Requiring Acyl Carrier Protein-Tethered Substrates. 10.1016/bs.mie.2018.01.028
Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic Fibrosis 10.1128/msystems.00375-19
Feature-based molecular networking in the GNPS analysis environment. 10.1038/s41592-020-0933-6
Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors. 10.3390/md18020124
Global chemical effects of the microbiome include new bile-acid conjugations. 10.1038/s41586-020-2047-9
Differences in Cystic Fibrosis-Associated Burkholderia spp. Bacteria Metabolomes after Exposure to the Antibiotic Trimethoprim. 10.1021/acsinfecdis.9b00513
Precursor-Guided Mining of Marine Sponge Metabolomes Lends Insight into Biosynthesis of Pyrrole-Imidazole Alkaloids. 10.1021/acschembio.0c00375
A community resource for paired genomic and metabolomic data mining. 10.1038/s41589-020-00724-z
Presence of Bromotyrosine Alkaloids in Marine Sponges Is Independent of Metabolomic and Microbiome Architectures. 10.1128/msystems.01387-20
LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome. 10.1016/j.cell.2021.04.001
Raquel Castelo Branco
Castelo Branco Raquel
ORCID: 0000-0001-6627-0140
First record of toxins associated with cyanobacterial blooms in oligotrophic North Patagonian lakes of Chile-a genomic approach 10.1002/iroh.201401780
Bacterial community characterization and biogeochemistry of sediments from a tropical upwelling system (Cabo Frio, Southeastern Brazil) 10.1016/j.csr.2016.10.001
Cyanobacterial Diversity in Microbial Mats from the Hypersaline Lagoon System of Araruama, Brazil: An In-depth Polyphasic Study 10.3389/fmicb.2017.01233
Cyanobacterial diversity held in microbial biological resource centers as a biotechnological asset: the case study of the newly established LEGE culture collection 10.1007/s10811-017-1369-y
Morphological and molecular characterization of cyanobacterial isolates from the mouth of the amazon river 10.11646/phytotaxa.387.4.1
GST transcriptional changes induced by a toxic Microcystis aeruginosa strain in two bivalve species during exposure and recovery phases 10.1007/s10646-018-1980-y
Structure of hierridin c, synthesis of hierridins b and c, and evidence for prevalent alkylresorcinol biosynthesis in picocyanobacteria 10.1021/acs.jnatprod.8b01038
Effects of two toxic cyanobacterial crude extracts containing microcystin-LR and cylindrospermopsin on the growth and photosynthetic capacity of the microalga Parachlorella kessleri 10.1016/j.algal.2018.07.016
Inhibition of bacterial and fungal biofilm formation by 675 extracts from microalgae and cyanobacteria 10.3390/antibiotics8020077
The Extremophile Endolithella mcmurdoensis gen. et sp. nov. (Trebouxiophyceae, Chlorellaceae), A New Chlorella-like Endolithic Alga From Antarctica 10.1111/jpy.12940
First detection of microcystin-lr in the amazon river at the drinking water treatment plant of the municipality of Macapá, Brazil 10.3390/toxins11110669
Distribution and diversity of dimetal-carboxylate halogenases in cyanobacteria 10.1101/2021.01.05.425448
Biosynthesis of Chlorinated Lactylates in Sphaerospermopsis sp. LEGE 00249 10.1021/acs.jnatprod.0c00950
Chlorosphaerolactylates A−D: Natural lactylates of chlorinated fatty acids isolated from the cyanobacterium sphaerospermopsis sp. Lege 00249 10.1021/acs.jnatprod.0c00072
Absence of cyanotoxins in llayta, edible nostocaceae colonies from the andes highlands 10.3390/toxins12060382
The phylogenetic placement of Temnogametum (Zygnemataceae) and description of Temnogametum iztacalense sp. nov., from a tropical high mountain lake in Mexico 10.1080/09670262.2020.1789226
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
Raphael Reher
Reher Raphael
ORCID: 0000-0002-5858-1173
A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria 10.3390/md19010020
Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra 10.1038/s41587-020-0740-8
Heterologous Expression of Cryptomaldamide in a Cyanobacterial Host 10.1021/acssynbio.0c00431
Cell‐permeable high‐affinity tracers for G q proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors 10.1111/bph.14960
A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products 10.1021/jacs.9b13786
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain 10.1021/acs.jmedchem.9b00294
Structural and Dynamical Basis of G Protein Inhibition by YM-254890 and FR900359: An Inhibitor in Action 10.1021/acs.jcim.9b00433
Direct targeting of Gαq and Gα11 oncoproteins in cancer cells 10.1126/scisignal.aau5948
Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity 10.1074/jbc.ra118.007250
Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq‐Signaling Inhibitor FR900359 10.1002/anie.201707996
Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359 10.1021/acs.jnatprod.8b00222
Deciphering Specificity Determinants for FR900359-Derived Gqα Inhibitors Based on Computational and Structure-Activity Studies 10.1002/cmdc.201800304
Lack of beta-arrestin signaling in the absence of active G proteins 10.1038/s41467-017-02661-3
The genome analysis of C andidatus  Burkholderia crenata reveals that secondary metabolism may be a key function of the A rdisia crenata leaf nodule symbiosis 10.1111/1462-2920.13184
Shaurya Chanana
Chanana Shaurya
ORCID: 0000-0002-3021-2210
hcapca: Automated Hierarchical Clustering and Principal Component Analysis of Large Metabolomic Datasets in R 10.3390/metabo10070297
Natural Product Discovery Using Planes of Principal Component Analysis in R (PoPCAR) 10.3390/metabo7030034
Nanogel-DFO conjugates as a model to investigate pharmacokinetics, biodistribution, and iron chelation in vivo 10.1016/j.ijpharm.2018.01.004
Brackish habitat dictates cultivable Actinobacterial diversity from marine sponges 10.1371/journal.pone.0176968
MS-Derived Isotopic Fine Structure Reveals Forazoline A as a Thioketone-Containing Marine-Derived Natural Product 10.1021/acs.orglett.9b04535
Phallusialides A–E, Pyrrole-Derived Alkaloids Discovered from a Marine-Derived Micromonospora sp. Bacterium Using MS-Based Metabolomics Approaches 10.1021/acs.jnatprod.9b00808
A marine microbiome antifungal targets urgent-threat drug-resistant fungi 10.1126/science.abd6919
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
Emily Pierce
Pierce Emily / Emily C. Pierce
ORCID: 0000-0002-9960-0270
Ketocarotenoid Production in Soybean Seeds through Metabolic Engineering 10.1371/journal.pone.0138196
Changes in the genetic requirements for microbial interactions with increasing community complexity 10.7554/elife.37072
BLANKA: an Algorithm for Blank Subtraction in Mass Spectrometry of Complex Biological Samples 10.1007/s13361-019-02185-8
Bacterial–fungal interactions revealed by genome-wide analysis of bacterial mutant fitness 10.1038/s41564-020-00800-z
High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival 10.1371/journal.pgen.1007301
American Gut: an Open Platform for Citizen Science Microbiome Research. 10.1128/msystems.00031-18
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
Diego Francisco Romero Hinojosa
Romero Hinojosa Diego Francisco / Romero, Diego
ORCID: 0000-0002-2052-6515
The Podosphaera xanthii haustorium, the fungal Trojan horse of cucurbit-powdery mildew interactions 10.1016/j.fgb.2014.08.006
Functional analysis of the accessory protein TapA in Bacillus subtilis amyloid fiber assembly 10.1128/JB.01363-13
Surfactin triggers biofilm formation of Bacillus subtilis in melon phylloplane and contributes to the biocontrol activity 10.1111/1462-2920.12271
Functional amyloids in bacteria 10.2436/20.1501.01.208
Evaluation of the effectiveness of biocontrol bacteria against avocado white root rot occurring under commercial greenhouse plant production conditions 10.1016/j.biocontrol.2013.08.009
Bacterial determinants of the social behavior of Bacillus subtilis 10.1016/j.resmic.2013.06.004
Isolation, characterization, and aggregation of a structured bacterial matrix precursor 10.1074/jbc.M113.453605
The antagonistic strain Bacillus subtilisUMAF6639 also confers protection to melon plants against cucurbit powdery mildew by activation of jasmonate- and salicylic acid-dependent defence responses 10.1111/1751-7915.12028
Biofilm inhibitors that target amyloid proteins 10.1016/j.chembiol.2012.10.021
Calcium causes multimerization of the large adhesin LapF and modulates biofilm formation by Pseudomonas putida 10.1128/JB.01094-12
Isolation and selection of plant growth-promoting rhizobacteria as inducers of systemic resistance in melon 10.1007/s11104-012-1173-z
The iturin-like lipopeptides are essential components in the biological control arsenal of Bacillus subtilis against bacterial diseases of cucurbits 10.1094/MPMI-06-11-0162
Antibiotics as signal molecules 10.1021/cr2000509
Will biofilm disassembly agents make it to market? 10.1016/j.tim.2011.03.003
An accessory protein required for anchoring and assembly of amyloid fibres in B-subtilis biofilms 10.1111/j.1365-2958.2011.07653.x
Plant protection and growth stimulation by microorganisms: Biotechnological applications of Bacilli in agriculture 10.1016/j.copbio.2010.12.003
Sensitivities to DMI fungicides in populations of podosphaera fusca in south central Spain 10.1002/ps.1948
D-Amino acids trigger biofilm disassembly 10.1126/science.1188628
Amyloid fibers provide structural integrity to Bacillus subtilis biofilms 10.1073/pnas.0910560107
The powdery mildew fungus Podosphaera fusca (synonym Podosphaera xanthii), a constant threat to cucurbits 10.1111/j.1364-3703.2008.00527.x
Comparative histochemical analyses of oxidative burst and cell wall reinforcement in compatible and incompatible melon-powdery mildew (Podosphaera fusca) interactions 10.1016/j.jplph.2008.04.020
Evaluation of biological control agents for managing cucurbit powdery mildew on greenhouse-grown melon 10.1111/j.1365-3059.2007.01684.x
Isolation and characterization of antagonistic Bacillus subtilis strains from the avocado rhizoplane displaying biocontrol activity 10.1111/j.1365-2672.2007.03433.x
Effect of lipopeptides of antagonistic strains of Bacillus subtilis on the morphology and ultrastructure of the cucurbit fungal pathogen Podosphaera fusca 10.1111/j.1365-2672.2007.03323.x
A nonribosomal peptide synthetase gene (mgoA) of Pseudomonas syringae pv. syringae is involved in mangotoxin biosynthesis and is required for full virulence 10.1094/MPMI-20-5-0500
The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward Podosphaera fusca 10.1094/MPMI-20-4-0430
Transformation of undomesticated strains of Bacillus subtilis by protoplast electroporation 10.1016/j.mimet.2006.01.005
Occurrence and distribution of resistance to QoI fungicides in populations of Podosphaera fusca in south central Spain 10.1007/s10658-006-9014-7
Long-term preservation of Podosphaera fusca using silica gel 10.1111/j.1439-0434.2006.01086.x
Isolation and evaluation of antagonistic bacteria towards the cucurbit powdery mildew fungus Podosphaera fusca 10.1007/s00253-003-1439-8
Effect of mycoparasitic fungi on the development of Sphaerotheca fusca in melon leaves 10.1017/S0953756202006974
A genomic region involved in the formation of adhesin fibers in Bacillus cereus biofilms 10.3389/fmicb.2014.00745
Comparative genomics within the bacillus genus reveal the singularities of two robust bacillus amyloliquefaciens biocontrol strains 10.1094/MPMI-02-15-0023-R
Transient transformation of Podosphaera xanthii by electroporation of conidia 10.1186/s12866-014-0338-8
Transformation of the cucurbit powdery mildew pathogen Podosphaera xanthii by Agrobacterium tumefaciens 10.1111/nph.14297
Unicellular but not asocial. Life in community of a bacterium 10.2436/20.1501.01.266
Analysis of β-tubulin-carbendazim interaction reveals that binding site for MBC fungicides does not include residues involved in fungicide resistance 10.1038/s41598-018-25336-5
Functional Amyloids in Health and Disease 10.1016/j.jmb.2018.07.024
Aflatoxin degradation by Bacillus subtilis UTB1 is based on production of an oxidoreductase involved in bacilysin biosynthesis 10.1016/j.foodcont.2018.03.002
Transformation by growth onto agro-infiltrated tissues (TGAT), a simple and efficient alternative for transient transformation of the cucurbit powdery mildew pathogen Podosphaera xanthii 10.1111/mpp.12722
The race for antimicrobials in the multidrug resistance era 10.1111/1751-7915.12884
Beyond the expected: the structural and functional diversity of bacterial amyloids 10.1080/1040841X.2018.1491527
The functional characterization of podosphaera xanthii candidate effector genes reveals novel target functions for fungal pathogenicity 10.1094/MPMI-12-17-0318-R
The extracellular matrix protects Bacillus subtilis colonies from Pseudomonas invasion and modulates plant co-colonization 10.1038/s41467-019-09944-x
Molecular architecture of bacterial amyloids in Bacillus biofilms. 10.1096/fj.201900831r
Biofilm formation displays intrinsic offensive and defensive features of Bacillus cereus 10.1038/s41522-019-0112-7
Two genomic regions encoding exopolysaccharide production systems have complementary functions in B. cereus multicellularity and host interaction 10.1038/s41598-020-57970-3
Dual functionality of the amyloid protein TasA in Bacillus physiology and fitness on the phylloplane 10.1038/s41467-020-15758-z
The extracellular matrix protein TasA is a developmental cue that maintains a motile subpopulation within Bacillus subtilis biofilms. 10.1126/scisignal.aaw8905
More than words: the chemistry behind the interactions in the plant holobiont 10.1111/1462-2920.15197
Biological Control of Phytopathogenic Fungi by Aerobic Endospore-Formers 10.1007/978-3-642-19577-8_8
Multifunctional Amyloids in the Biology of Gram-Positive Bacteria 10.3390/microorganisms8122020
Sporulation is dispensable for the vegetable-associated life cycle of the human pathogen Bacillus cereus 10.1101/2021.01.15.426836
Whole Genome Sequencing and Root Colonization Studies Reveal Novel Insights in the Biocontrol Potential and Growth Promotion by Bacillus subtilis MBI 600 on Cucumber. 10.3389/fmicb.2020.600393
A Hybrid Genome Assembly Resource for Podosphaera xanthii, the Main Causal Agent of Powdery Mildew Disease in Cucurbits. 10.1094/mpmi-08-20-0237-a
Effectors with chitinase activity (EWCAs), a family of conserved, secreted fungal chitinases that suppress chitin-triggered immunity 10.1093/plcell/koab011
Sporulation is dispensable for the vegetable‐associated life cycle of the human pathogen Bacillus cereus 10.1111/1751-7915.13816
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
Christian Martin H.
Martin H. Christian
ORCID: 0000-0002-9604-6737
Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and molecular networking 10.1038/s41598-019-39583-7
Fungus-Growing Ant's Microbial Interaction of Streptomyces sp. and Escovopsis sp. through Molecular Networking and MALDI Imaging 10.1177/1934578x1901400117
Genome Mining, Microbial Interactions, and Molecular Networking Reveals New Dibromoalterochromides from Strains of Pseudoalteromonas of Coiba National Park-Panama 10.3390/md18090456
Metabolites from Microbes Isolated from the Skin of the Panamanian Rocket Frog Colostethus panamansis (Anura: Dendrobatidae) 10.3390/metabo10100406
Feature-based molecular networking in the GNPS analysis environment 10.1038/s41592-020-0933-6
Reproducible molecular networking of untargeted mass spectrometry data using GNPS 10.1038/s41596-020-0317-5
Metabolomic signatures of coral bleaching history. 10.1038/s41559-020-01388-7
A community resource for paired genomic and metabolomic data mining. 10.1038/s41589-020-00724-z
Gajender Aleti
Aleti Gajender
ORCID: 0000-0002-1867-9758
Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease 10.1128/mbio.00321-19
Secondary metabolite genes encoded by potato rhizosphere microbiomes in the Andean highlands are diverse and vary with sampling site and vegetation stage 10.1038/s41598-017-02314-x
Microbe and plant assisted-remediation of organic xenobiotics and its enhancement by genetically modified organisms and recombinant technology: A review 10.1016/j.scitotenv.2018.02.037
The draft genome sequence of Paenibacillus polymyxa strain CCI-25 encompasses high potential for secondary metabolite production 10.1128/genomeA.00366-16
Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression 10.1016/j.ydbio.2011.04.030
Host-Microbial Interactions in Systemic Lupus Erythematosus and Periodontitis 10.3389/fimmu.2019.02602
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages 10.1016/j.foodchem.2019.125290
Qualitative analysis of biosurfactants from Bacillus species exhibiting antifungal activity 10.1371/journal.pone.0198107
Surfactin variants mediate species-specific biofilm formation and root colonization in Bacillus 10.1111/1462-2920.13405
Differing salivary microbiome diversity, community and diurnal rhythmicity in association with affective state and peripheral inflammation in adults 10.1016/j.bbi.2020.02.004
Correction: Qualitative analysis of biosurfactants from Bacillus species exhibiting antifungal activity(PLoS ONE (2018) 13:6 (e0198107) DOI: 10.1371/journal.pone.0198107) 10.1371/journal.pone.0201624
Genome mining: Prediction of lipopeptides and polyketides from Bacillus and related Firmicutes 10.1016/j.csbj.2015.03.003
A community resource for paired genomic and metabolomic data mining. 10.1038/s41589-020-00724-z
Oral Microbial Species and Virulence Factors Associated with Oral Squamous Cell Carcinoma. 10.1007/s00248-020-01596-5
ReDU: a framework to find and reanalyze public mass spectrometry data. 10.1038/s41592-020-0916-7
Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides 10.1101/2021.08.10.21255754
Anna Edlund
Edlund Anna
ORCID: 0000-0002-3394-4804
Discovery of a Novel Periodontal Disease-Associated Bacterium 10.1007/s00248-018-1200-6
Uncovering complex microbiome activities via metatranscriptomics during 24 hours of oral biofilm assembly and maturation 10.1186/s40168-018-0591-4
Establishing microbial composition measurement standards with reference frames. 10.1038/s41467-019-10656-5
Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease. 10.1128/mBio.00321-19
Klebsiella and Providencia emerge as lone survivors following long-term starvation of oral microbiota. 10.1073/pnas.1820594116
Quorum Sensing Modulates the Epibiotic-Parasitic Relationship Between Actinomyces odontolyticus and Its Saccharibacteria epibiont, a Nanosynbacter lyticus Strain, TM7x. 10.3389/fmicb.2018.02049
Exploiting the Oral Microbiome to Prevent Tooth Decay: Has Evolution Already Provided the Best Tools? 10.3389/fmicb.2018.03323
Correction for Morton et al., "Uncovering the Horseshoe Effect in Microbial Analyses". 10.1128/mSystems.00006-18
Metabolic Fingerprints from the Human Oral Microbiome Reveal a Vast Knowledge Gap of Secreted Small Peptidic Molecules. 10.1128/mSystems.00058-17
Uncovering the Horseshoe Effect in Microbial Analyses. 10.1128/mSystems.00166-16
The Denture-Associated Oral Microbiome in Health and Stomatitis. 10.1128/mSphere.00215-16
Spatial Molecular Architecture of the Microbial Community of a Peltigera Lichen. 10.1128/mSystems.00139-16
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. 10.1038/nbt.3597
Metagenome and Metatranscriptome Analyses Using Protein Family Profiles. 10.1371/journal.pcbi.1004991
High-Quality Draft Genome Sequence of Low-pH-Active Veillonella parvula Strain SHI-1, Isolated from Human Saliva within an In Vitro Oral Biofilm Model. 10.1128/genomeA.01684-15
Draft Genome Sequence of "Candidatus Bacteroides periocalifornicus," a New Member of the Bacteriodetes Phylum Found within the Oral Microbiome of Periodontitis Patients. 10.1128/genomeA.01485-15
Meta-omics uncover temporal regulation of pathways across oral microbiome genera during in vitro sugar metabolism. 10.1038/ismej.2015.72
Bacteria-mediated effects of antibiotics on Daphnia nutrition. 10.1021/acs.est.5b00833
Bacteriophage and their potential roles in the human oral cavity. 10.3402/jom.v7.27423
Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle. 10.1073/pnas.1419038112
An in vitro biofilm model system maintaining a highly reproducible species and metabolic diversity approaching that of the human oral microbiome. 10.1186/2049-2618-1-25
Candidate phylum TM6 genome recovered from a hospital sink biofilm provides genomic insights into this uncultivated phylum. 10.1073/pnas.1219809110
Genome of the pathogen Porphyromonas gingivalis recovered from a biofilm in a hospital sink using a high-throughput single-cell genomics platform. 10.1101/gr.150433.112
Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. 10.1016/j.jprot.2012.05.036
Antibiotic-induced change of bacterial communities associated with the copepod Nitocra spinipes. 10.1371/journal.pone.0033107
Microdiversity and evidence for high dispersal rates in the marine actinomycete 'Salinispora pacifica'. 10.1111/j.1462-2920.2011.02641.x
Geographic distribution of secondary metabolite genes in the marine actinomycete Salinispora arenicola. 10.1128/AEM.00611-11
Use of bromodeoxyuridine immunocapture to identify psychrotolerant phenanthrene-degrading bacteria in phenanthrene-enriched polluted Baltic Sea sediments. 10.1111/j.1574-6941.2008.00513.x
Active bacterial community structure along vertical redox gradients in Baltic Sea sediment. 10.1111/j.1462-2920.2008.01624.x
Changes in active bacterial communities before and after dredging of highly polluted Baltic Sea sediments. 10.1128/AEM.00971-06
Microbial community structure in polluted Baltic Sea sediments. 10.1111/j.1462-2920.2005.00887.x
Cariogenic Streptococcus mutans Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal Colonization 10.1021/acsinfecdis.9b00365
Caries-Associated Biosynthetic Gene Clusters in Streptococcus mutans 10.1177/0022034520914519
Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore 10.1128/mSystems.00161-20
Composite Long- and Short-Read Sequencing Delivers a Complete Genome Sequence of B04Sm5, a Reutericyclin- and Mutanocyclin-Producing Strain of Streptococcus mutans 10.1128/MRA.01067-20
Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules 10.1101/gr.265645.120
The Oral Host–Microbial Interactome: An Ecological Chronometer of Health? 10.1016/j.tim.2020.11.004
A community resource for paired genomic and metabolomic data mining. 10.1038/s41589-020-00724-z
Ellis O'Neill
O'Neill Ellis / Ellis C. O'Neill
ORCID: 0000-0002-5941-2806
Expression and characterization of 4-α-glucanotransferase genes from Manihot esculenta Crantz and Arabidopsis thaliana and their use for the production of cycloamyloses 10.1016/j.procbio.2013.10.009
Sugar-coated sensor chip and nanoparticle surfaces for the in vitro enzymatic synthesis of starch-like materials 10.1039/c3sc51829a
A one-pot enzymatic approach to the O-fluoroglucoside of N-methylanthranilate 10.1016/j.bmc.2013.05.057
Antibiotics: Blocking bacterial defences 10.1038/nchem.1718
An expedient enzymatic route to isomeric 2-, 3- and 6-monodeoxy-monofluoro- maltose derivatives 10.1016/j.carres.2012.05.026
Enzymatic synthesis of nucleobase-modified UDP-sugars: Scope and limitations 10.1016/j.carres.2014.12.005
Enzymatic synthesis using glycoside phosphorylases 10.1016/j.carres.2014.06.010
Crystal structure of a novel two domain GH78 family α-rhamnosidase from Klebsiella oxytoca with rhamnose bound 10.1002/prot.24807
The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry 10.1039/C5MB00319A
Underpinning Starch Biology with in vitro Studies on Carbohydrate-Active Enzymes and Biosynthetic Glycomaterials. 10.3389/fbioe.2015.00136
Euglena in time: Evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry 10.1016/j.pisc.2015.07.002
Gene Discovery for Synthetic Biology: Exploring the Novel Natural Product Biosynthetic Capacity of Eukaryotic Microalgae 10.1016/bs.mie.2016.03.005
Engineering biosynthesis of high-value compounds in photosynthetic organisms 10.1080/07388551.2016.1237467
Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols 10.1021/acs.jnatprod.6b00722
Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes. 10.1016/j.carres.2016.11.017
Cellodextrin phosphorylase from Ruminiclostridium thermocellum : X-ray crystal structure and substrate specificity analysis 10.1016/j.carres.2017.07.005
Biomolecular Engineering of Microorganisms for Natural Products Production 10.1016/b978-0-12-409547-2.12791-x
Exploring the Glycans of Euglena Gracilis 10.20944/preprints201711.0051.v1
An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri 10.1093/gbe/evx152
Targeted antibiotic discovery through biosynthesis-associated resistance determinants: target directed genome mining 10.1080/1040841X.2019.1590307
Transcriptome, proteome and draft genome of Euglena gracilis 10.1186/s12915-019-0626-8
Insights into toxic Prymnesium parvum blooms: the role of sugars and algal viruses 10.1042/bst20170393
Euglena Central Metabolic Pathways and Their Subcellular Locations 10.20944/preprints201905.0020.v1
Euglena Central Metabolic Pathways and Their Subcellular Locations 10.3390/metabo9060115
Exploring the Glycans of Euglena gracilis 10.3390/biology6040045
Exploring the Glycans of Euglena gracilis 10.20944/preprints201711.0051.v2
Proteome of the secondary plastid of Euglena gracilis reveals metabolic quirks and colourful history 10.1242/prelights.9503
Mining Natural Product Biosynthesis in Eukaryotic Algae 10.3390/md18020090
Using new techniques to study old favorites: A case study of Euglena 10.1016/b978-0-12-818305-2.00010-3
A community resource for paired genomic and metabolomic data mining. 10.1038/s41589-020-00724-z
Deepa Acharya
Acharya Deepa
ORCID: 0000-0001-6627-5865
GNPS Dashboard: Collaborative Analysis of Mass Spectrometry Data in the Web Browser 10.1101/2021.04.05.438475
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
Chemically informed analyses of metabolomics mass spectrometry data with Qemistree 10.1038/s41589-020-00677-3
Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis 10.1021/acschembio.9b00223
Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery 10.1038/s41467-021-23502-4
Draft Genome Sequence of Micromonospora sp. Strain WMMA1996, a Marine Sponge-Associated Bacterium 10.1128/genomea.00077-18
Marianna Iorio
Iorio Marianna
ORCID: 0000-0001-8669-5875
Multi-omics Study of Planobispora rosea, Producer of the Thiopeptide Antibiotic GE2270A. 10.1128/msystems.00341-21
Antibacterial Paramagnetic Quinones from Actinoallomurus 10.1021/acs.jnatprod.6b00654
Antibacterial Aromatic Polyketides Incorporating the Unusual Amino Acid Enduracididine 10.1021/acs.jnatprod.8b00354
Novel Polyethers from Screening Actinoallomurus spp. 10.3390/antibiotics7020047
A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity 10.1016/j.chembiol.2018.02.008.
A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity 10.1021/cb400692w.
Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency. 10.1021/acs.jnatprod.5b00576
Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270. 10.1016/j.chembiol.2013.07.005
Chrolactomycins from the Actinomycete Actinospica 10.1021/np300470f
Discovering new bioactive molecules from microbial sources 10.1111/1751-7915.12123
Characterization of madurastatin C1, a novel siderophore from Actinomadura sp. 10.1038/ja.2012.10
Characterization of the Congeners in the Lantibiotic NAI-107 Complex 10.1021/np400702t
Sorption of phenanthrene by dissolved organic matter and its complex with aluminum oxide nanoparticles 10.1016/j.envpol.2008.05.003
Remediation of waters contaminated with ionic herbicides by sorption on polymerin 10.1016/j.watres.2007.08.015
Comparative Study on the Sorption Capacity of Cyhalofop Acid on Polymerin, Ferrihydrite, and on a Ferrihydrite−Polymerin Complex 10.1021/jf900573f
Synthesis, Characterization, and Sorption Capacity of Layered Double Hydroxides and Their Complexes with Polymerin 10.1021/jf904092n
Sustainable sorption strategies for removing Cr3+ from tannery process wastewater 10.1016/j.chemosphere.2013.03.051
Removal of 4-chloro-2-methylphenoxyacetic acid from water by sorption on carbon nanotubes and metal oxide nanoparticles 10.1039/c2ra00038e
Detoxification of olive mill wastewaters by zinc–aluminium layered double hydroxides 10.1016/j.clay.2011.07.003
Planomonospora: A Metabolomics Perspective on an Underexplored Actinobacteria Genus 10.1021/acs.jnatprod.0c00807
A community resource for paired genomic and metabolomic data mining. 10.1038/s41589-020-00724-z
Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain. 10.1038/s41598-021-84833-2
Effective approaches to discover new microbial metabolites in a large strain library. 10.1093/jimb/kuab017
Synthetic biology approaches to actinomycete strain improvement 10.1093/femsle/fnab060
Tam Dang
Dang Tam
ORCID: 0000-0002-3602-1917
Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats 10.1021/acs.analchem.6b03456
Total Synthesis and Biological Assessment of Novel Albicidins Discovered by Mass Spectrometric Networking 10.1002/chem.201704074
Bioactive Peptide Natural Products as Lead Structures for Medicinal Use 10.1021/acs.accounts.7b00159
Feature-based molecular networking in the GNPS analysis environment 10.1038/s41592-020-0933-6
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
Andrew McAvoy
McAvoy Andrew
ORCID: 0000-0002-3647-3956
HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer. 10.1128/jvi.00684-16
Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses. 10.3390/v11020136
Utilization of Feline ELISpot to Evaluate the Immunogenicity of a T Cell-Based FIV MAP Vaccine 10.1007/978-1-4939-8567-8_18
Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic Fibrosis. 10.1128/msystems.00375-19
Differences in Cystic Fibrosis-Associated Burkholderia spp. Bacteria Metabolomes after Exposure to the Antibiotic Trimethoprim. 10.1021/acsinfecdis.9b00513
A community resource for paired genomic and metabolomic data mining. 10.1038/s41589-020-00724-z
Laura Sanchez
Sanchez Laura
ORCID: 0000-0001-9223-7977
Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids 10.1371/journal.pone.0149603
Microbiota of Healthy Corals Are Active against Fungi in a Light-Dependent Manner 10.1021/cb500432j
Mass spectrometry of natural products: current, emerging and future technologies 10.1039/c4np00044g
Versatile Method for the Detection of Covalently Bound Substrates on Solid Supports by DART Mass Spectrometry 10.1021/ol201404v
Almiramides A−C: Discovery and Development of a New Class of Leishmaniasis Lead Compounds 10.1021/jm100265s
Examination of the Mode of Action of the Almiramide Family of Natural Products against the Kinetoplastid Parasite Trypanosoma brucei 10.1021/np300834q
Molecular Networking as a Dereplication Strategy 10.1021/np400413s
Examining the Fish Microbiome: Vertebrate-Derived Bacteria as an Environmental Niche for the Discovery of Unique Marine Natural Products 10.1371/journal.pone.0035398
Analytical chemistry: Virulence caught green-handed 10.1038/nchem.1583
Ralstonia solanacearum lipopeptide induces chlamydospore development in fungi and facilitates bacterial entry into fungal tissues 10.1038/ismej.2016.32
Real-Time Metabolomics on Living Microorganisms Using Ambient Electrospray Ionization Flow-Probe 10.1021/ac401613x
An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria 10.1128/msystems.00028-15
Pyrroloacridine Alkaloids from Plakortis quasiamphiaster :  Structures and Bioactivity 10.1021/np060585w
Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides 10.1038/nmicrobiol.2016.197
Spatial Molecular Architecture of the Microbial Community of a Peltigera Lichen 10.1128/msystems.00139-16
Calling All Hosts: Bacterial Communication In Situ 10.1016/j.chempr.2017.02.001
Coproporphyrin III Produced by the Bacterium Glutamicibacter arilaitensis Binds Zinc and Is Upregulated by Fungi in Cheese Rinds. 10.1128/mSystems.00036-18
Imaging Mass Spectrometry Reveals Crosstalk between the Fallopian Tube and the Ovary that Drives Primary Metastasis of Ovarian Cancer. 10.1021/acscentsci.8b00405
Whole Cell MALDI Fingerprinting Is a Robust Tool for Differential Profiling of Two-Component Mammalian Cell Mixtures. 10.1007/s13361-018-2088-6
Capturing Small Molecule Communication Between Tissues and Cells Using Imaging Mass Spectrometry. 10.3791/59490
BLANKA: an Algorithm for Blank Subtraction in Mass Spectrometry of Complex Biological Samples. 10.1007/s13361-019-02185-8
Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data. 10.3791/59219
Staring into the void: demystifying microbial metabolomics. 10.1093/femsle/fnz135
Minimizing Taxonomic and Natural Product Redundancy in Microbial Libraries Using MALDI-TOF MS and the Bioinformatics Pipeline IDBac. 10.1021/acs.jnatprod.9b00168
Optimization of a minimal sample preparation protocol for imaging mass spectrometry of unsectioned juvenile invertebrates 10.1002/jms.4458
Chemically transformed monolayers on acene thin films for improved metal/organic interfaces 10.1039/c9cc07234a
The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806
Biofilm Inhibitor Taurolithocholic Acid Alters Colony Morphology, Specialized Metabolism, and Virulence of Pseudomonas aeruginosa 10.1021/acsinfecdis.9b00424
Detection of Ovarian Cancer Using Samples Sourced from the Vaginal Microenvironment 10.1021/acs.jproteome.9b00694
A Call to Action: the Need for Standardization in Developing Open-Source Mass Spectrometry-Based Methods for Microbial Subspecies Discrimination 10.1128/msystems.00813-19
Addition of insoluble fiber to isolation media allows for increased metabolite diversity of lab-cultivable microbes derived from zebrafish gut samples 10.1080/19490976.2020.1740073
Imaging mass spectrometry for natural products discovery: a review of ionization methods 10.1039/c9np00038k
Evaluation of Data Analysis Platforms and Compatibility with MALDI-TOF Imaging Mass Spectrometry Data Sets 10.1021/jasms.0c00039
The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells 10.1182/blood.2019004415
Bacterial–fungal interactions revealed by genome-wide analysis of bacterial mutant fitness 10.1038/s41564-020-00800-z
Fallopian Tube-Derived Tumor Cells Induce Testosterone Secretion from the Ovary, Increasing Epithelial Proliferation and Invasion 10.3390/cancers13081925
A Family of Nonribosomal Peptides Modulate Collective Behavior in Pseudovibrio Bacteria Isolated from Marine Sponges** 10.1002/anie.202017320
A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z
A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ 10.1128/mbio.03637-20
Models for measuring metabolic chemical changes in the metastasis of high grade serous ovarian cancer: fallopian tube, ovary, and omentum 10.1039/d1mo00074h