Dragocins A−D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium
Hyukjae Choi Niclas Engene Tara Byrum Sunghoon Hwang Dong-Chan Oh William H. Gerwick
Organic Letters, 2019-1-4
William Gerwick
Gerwick William
ORCID: 0000-0003-1403-4458
Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata 10.3390/md15040121
Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group 10.3390/md16050163
Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease 10.3390/molecules23061472
MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria 10.3390/md16120505
Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore 10.3390/md17010072
Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke 10.3390/md18070374
A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria 10.3390/md19010020
Kalkitoxin Reduces Osteoclast Formation and Resorption and Protects against Inflammatory Bone Loss 10.3390/ijms22052303
Dudawalamides A–D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens 10.1021/acs.jnatprod.7b00034
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity 10.1021/acs.jmedchem.7b00671
5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34 10.3390/md15080260
The Face of a Molecule 10.1021/acs.jnatprod.7b00624
Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research 10.1038/s41598-017-13923-x
A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit 10.1021/acschembio.7b00746
Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group 10.1021/acs.jnatprod.7b00917
Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp. 10.1021/acs.joc.8b00028
Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β 10.1021/acschemneuro.7b00527
Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module 10.1021/acschembio.8b00252
Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta 10.1021/acschembio.8b00910
Structural Basis of Polyketide Synthase O-Methylation 10.1021/acschembio.8b00687
Dragocins A−D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium 10.1021/acs.orglett.8b03712
Marine natural products as potential anti-tubercular agents 10.1016/j.ejmech.2019.01.026
Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp. 10.1021/acs.orglett.8b04050
Nature's Combinatorial Biosynthesis Produces Vatiamides A–F 10.1002/anie.201902571
Nature's Combinatorial Biosynthesis Produces Vatiamides A–F 10.1002/ange.201902571
Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens 10.1021/acs.jnatprod.9b00549
Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain 10.1021/acs.jmedchem.9b00294
Commensal oralRothia mucilaginosaproduces enterobactin – a metal chelating siderophore 10.1101/2020.02.20.956391
Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity 10.3390/molecules25071604
Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore 10.1128/mSystems.00161-20
Correction to “Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp.” 10.1021/acs.orglett.0c02252
The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria 10.3390/md18100508
Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2 10.1021/acs.jnatprod.0c00968
Total Synthesis of Laucysteinamide A, a Monomeric Congener of Somocystinamide A 10.1021/acs.jnatprod.0c01317
Cyanobacteria-shrimp colonies in the Mariana Islands 10.1007/s10452-021-09837-6
Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium 10.1021/acs.jnatprod.0c01383
SIRT1 Activation Enhancing 8,3′-Neolignans from the Twigs of Corylopsis coreana Uyeki 10.3390/plants10081684
First Total Synthesis and Structure–Activity Relationship of Iheyamide A, an Antitrypanosomal Linear Peptide Isolated from a Dapis sp. Marine Cyanobacterium 10.1021/acs.jnatprod.1c00792
Hyukjae Choi
Choi Hyukjae
ORCID: 0000-0002-7707-4767
Antibacterial Bicyclic Fatty Acids from a Korean Colonial Tunicate Didemnum sp. 10.3390/md19090521
Chemical Investigation of Diketopiperazines and N-phenethylacetamide Isolated from Aquimarina sp. MC085 and Their Effect on TGF-β-Induced Epithelial–Mesenchymal Transition 10.3390/app11198866
Three diketopiperazines from marine-derived bacteria inhibit LPS-induced endothelial inflammatory responses 10.1016/j.bmcl.2016.03.030
Cinnamomulactone, a new butyrolactone from the twigs of Cinnamomum cassia and its inhibitory activity of matrix metalloproteinases 10.1007/s12272-016-0877-7
Characterization of Marinovum faecis sp. nov., an alphaproteobacterium isolated from marine sediment 10.1007/s10482-017-0867-x
Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway 10.1021/acs.jnatprod.7b00734
Dragocins A−D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium 10.1021/acs.orglett.8b03712
Saccharoquinoline, a Cytotoxic Alkaloidal Meroterpenoid from Marine-Derived Bacterium Saccharomonospora sp. 10.3390/md17020098
Polyphasic taxonomic analysis of Paracoccus ravus sp. nov., an alphaproteobacterium isolated from marine sediment 10.1093/femsle/fnz184
Marine Microorganism-Derived Macrolactins Inhibit Inflammatory Mediator Effects in LPS-Induced Macrophage and Microglial Cells by Regulating BACH1 and HO-1/Nrf2 Signals through Inhibition of TLR4 Activation 10.3390/molecules25030656
Purification of Phenylpropanoids from the Scaly Bulbs of Lilium Longiflorum by CPC and Determination of Their DPP-IV Inhibitory Potentials 10.1021/acsomega.9b03649
Isolation of Unstable Isomers of Lucilactaene and Evaluation of Anti-Inflammatory Activity of Secondary Metabolites Produced by the Endophytic Fungus Fusarium sp. QF001 from the Roots of Scutellaria baicalensis 10.3390/molecules25040923
Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer Cells 10.1021/acs.jnatprod.0c00815
Phytochemical constituents of leaves and twigs of Elaeagnus umbellata 10.1016/j.bse.2020.104178
Antioxidant, Pancreatic Lipase Inhibitory, and Tyrosinase Inhibitory Activities of Extracts of the Invasive Plant Spartina anglica (Cord-Grass) 10.3390/antiox10020242
Eudesmane and Eremophilane Sesquiterpenes from the Fruits of Alpinia oxyphylla with Protective Effects against Oxidative Stress in Adipose-Derived Mesenchymal Stem Cells 10.3390/molecules26061762
Estrogenic Effects of Extracts and Isolated Compounds from Belowground and Aerial Parts of Spartina anglica 10.3390/md19040210
Anticancer Activity of 2-O-caffeoyl Alphitolic Acid Extracted from the Lichen, Usnea barbata 2017-KL-10 10.3390/molecules26133937
In Vitro Metabolism Study of Seongsanamide A in Human Liver Microsomes Using Non-Targeted Metabolomics and Feature-Based Molecular Networking 10.3390/pharmaceutics13071031
Identification of the Active Ingredient and Beneficial Effects of Vitex rotundifolia Fruits on Menopausal Symptoms in Ovariectomized Rats 10.3390/biom11071033
Azaphilones from an Endophytic Penicillium sp. Prevent Neuronal Cell Death via Inhibition of MAPKs and Reduction of Bax/Bcl-2 Ratio 10.1021/acs.jnatprod.1c00298
Metabolite Profiling and Dipeptidyl Peptidase IV Inhibitory Activity of Coreopsis Cultivars in Different Mutations 10.3390/plants10081661
Inhibition of A549 Lung Cancer Cell Migration and Invasion by Ent-Caprolactin C via the Suppression of Transforming Growth Factor-β-Induced Epithelial—Mesenchymal Transition 10.3390/md19080465