The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni
Bibo-Verdugo, Betsaida
Wang, Steven C.
Almaliti, Jehad
Ta, Anh P.
Jiang, Zhenze
Wong, Derek A.
Lietz, Christopher B.
Suzuki, Brian M.
El-Saldary, Nelly
Hook, Vivian
Salvesen, Guy S.
Gerwick, William H.
Caffrey, Conor R.
O'Donoghue, Anthony J.
ACS Infectious Diseases, 2019
Zhenze Jiang
Jiang Zhenze
ORCID: 0000-0001-9570-1739
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry
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The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni
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Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing
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Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions
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jehad almaliti
almaliti jehad
ORCID: 0000-0002-3562-0846
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10.1021/acs.jnatprod.5b00301
Natural products inspired synthesis of neuroprotective agents against H2O2-induced cell death
10.1016/j.bmcl.2013.01.013
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The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni
10.1021/acsinfecdis.9b00237
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