A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells
Drake M. Mellott Chien-Te Tseng Aleksandra Drelich Pavla Fajtová Bala C. Chenna Demetrios H. Kostomiris Jason Hsu Jiyun Zhu Zane W. Taylor Klaudia I. Kocurek Vivian Tat Ardala Katzfuss Linfeng Li Miriam A. Giardini Danielle Skinner Ken Hirata Michael C. Yoon Sungjun Beck Aaron F. Carlin Alex E. Clark Laura Beretta Daniel Maneval Vivian Hook Felix Frueh Brett L. Hurst Hong Wang Frank M. Raushel Anthony J. O’Donoghue Jair Lage de Siqueira-Neto Thomas D. Meek James H. McKerrow
ACS Chemical Biology, 2021
https://doi.org/10.1021/acschembio.0c00875
Drake Mellott
Mellott Drake
ORCID: 0000-0002-8043-8170
Peptidomimetic Vinyl Heterocyclic Inhibitors of Cruzain Effect Antitrypanosomal Activity 10.1021/acs.jmedchem.9b02078
A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells 10.1101/2020.10.23.347534
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells 10.1021/acschembio.0c00875
Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis-2,3-Epoxy-Succinic Acid 10.1021/acschembio.0c00740
Bepridil is potent against SARS-CoV-2 in vitro 10.1073/pnas.2012201118
Bepridil is potent against SARS-CoV-2 In Vitro 10.1101/2020.05.23.112235
Dinitrosyl iron complexes (DNICs) as inhibitors of the SARS-CoV-2 main protease 10.1039/D1CC03103A
Michael Yoon
Yoon Michael
ORCID: 0000-0002-2900-5257
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages 10.1016/j.foodchem.2019.125290
Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders 10.1016/j.bbapap.2020.140428
Assessing the Acceptance of the Pay-For-Performance Model in a Segment of California Pharmacists https://doi.org/10.37901/jcphp17-00011
Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing 10.1021/acschemneuro.1c00133
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells 10.1021/acschembio.0c00875
Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions 10.1021/acschembio.1c00138
BALA CHANDRA CHENNA
CHENNA BALA CHANDRA
ORCID: 0000-0002-2660-5302
L-2-hydroxyglutarate: An epigenetic modifier and putative oncometabolite in renal cancer 10.1158/2159-8290.CD-13-0696
Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors 10.1016/j.ejmech.2010.05.024
Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase 10.1016/j.bmc.2010.04.020
Synthesis, separation and crystal structures of E and Z isomers of 3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acrylic acid 10.1007/s10870-007-9288-4
Erratum: Elevated levels of NO are localized to distal airways in asthma (Free Radical Biology and Medicine (2011) 50 (1679-1688)) 10.1016/j.freeradbiomed.2013.01.007
Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A 10.1016/j.bmcl.2007.10.051
Synthesis and the crystal structure of (E)-2-(7-(3-(Thiophen-2-yl) acrylamido)-2,3-dihydro-5-oxobenzo[e][1,4]oxazepin-1(5H)-yl)ethyl acetate 10.1007/s10870-009-9588-y
Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression 10.1371/journal.pone.0060478
Elevated levels of NO are localized to distal airways in asthma 10.1016/j.freeradbiomed.2011.03.015
Peptidomimetic Vinyl Heterocyclic Inhibitors of Cruzain Effect Antitrypanosomal Activity 10.1021/acs.jmedchem.9b02078
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells 10.1021/acschembio.0c00875
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases 10.1021/acs.jmedchem.1c00628
Ardala Katzfuss
Katzfuss Ardala / Ardala Breda
ORCID: 0000-0002-7177-9600
A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells 10.1101/2020.10.23.347534
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells 10.1021/acschembio.0c00875
Dinitrosyl iron complexes (DNICs) as inhibitors of the SARS-CoV-2 main protease 10.1039/D1CC03103A
Summary of the Sussex-Huawei locomotion-transportation recognition challenge
Observation of a manifold in the chaotic phase space of an asymmetric optical microcavity
Localized temporal variation of Earth's inner-core boundary from high-quality waveform doublets
Off-axis multi-wavelength dispersion controlling metalens for multi-color imaging
Impact of United States political sanctions on international collaborations and research in Iran