Paperbase

Sylvia Soldatou

Soldatou Sylvia

ORCID: 0000-0002-3868-102X

Email: sylvia.soldatou@gmail.com

Cold-water marine natural products, 2006 to 2016 10.1039/c6np00127k

Linking biosynthetic and chemical space to accelerate microbial secondary metabolite discovery 10.1093/femsle/fnz142

Sulfated Steroid–Amino Acid Conjugates from the Irish Marine Sponge Polymastia boletiformis 10.3390/md13041632

Accramycin A, A New Aromatic Polyketide, from the Soil Bacterium, Streptomyces sp. MA37 10.3390/molecules24183384

Awakening ancient polar Actinobacteria: diversity, evolution and specialized metabolite potential 10.1099/mic.0.000845

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Morphological, genotypic and metabolomic signatures confirm interfamilial hybridization between the ubiquitous kelps Macrocystis (Arthrothamnaceae) and Lessonia (Lessoniaceae) 10.1038/s41598-020-65137-3

Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions 10.1101/2020.06.12.148205

Screening Fungal Endophytes Derived from Under-Explored Egyptian Marine Habitats for Antimicrobial and Antioxidant Properties in Factionalised Textiles 10.3390/microorganisms8101617

Comparative Metabologenomics Analysis of Polar Actinomycetes 10.3390/md19020103

Degradation of Multiple Peptides by Microcystin-Degrader Paucibacter toxinivorans (2C20) 10.3390/toxins13040265

Antimicrobial and Antibiofilm Activities of the Fungal Metabolites Isolated from the Marine Endophytes Epicoccum nigrum M13 and Alternaria alternata 13A 10.3390/md19040232

Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions 10.1371/journal.pcbi.1008920

New directions and challenges in engineering biologically-enhanced biochar for biological water treatment. 10.1016/j.scitotenv.2021.148977

Jeffrey A. van Santen

van Santen Jeffrey A.

ORCID: 0000-0002-5424-804X

Dispersion Corrections Improve the Accuracy of Both Noncovalent and Covalent Interactions Energies Predicted by a Density-Functional Theory Approximation 10.1021/acs.jpca.5b02809

A computational and experimental re-examination of the reaction of the benzyloxyl radical with DMSO 10.1016/j.comptc.2015.10.030

MIBiG 2.0: a repository for biosynthetic gene clusters of known function 10.1093/nar/gkz882

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Microbial natural product databases: moving forward in the multi-omics era 10.1039/D0NP00053A

Bimodal Evans–Polanyi Relationships in Hydrogen Atom Transfer from C(sp3)–H Bonds to the Cumyloxyl Radical. A Combined Time-Resolved Kinetic and Computational Study 10.1021/jacs.1c05566

Development of an NMR-Based Platform for the Direct Structural Annotation of Complex Natural Products Mixtures 10.1021/acs.jnatprod.0c01076

Fausto Carnevale Neto

Carnevale Neto Fausto

ORCID: 0000-0002-9364-933X

Anti-inflammatory activity of Vismia guianensis (Aubl.) Pers. extracts and antifungal activity against Sporothrix schenckii 10.1016/j.jep.2016.11.030

Dereplication of Flavonoid Glycoconjugates from Adenocalymma imperatoris-maximilianii by Untargeted Tandem Mass Spectrometry-Based Molecular Networking 10.1055/s-0042-118712

Naturally occurring fluorescence in frogs 10.1073/pnas.1701053114

Partial least squares model and design of experiments toward the analysis of the metabolome of Jatropha gossypifolia leaves: Extraction and chromatographic fingerprint optimization 10.1002/jssc.201500892

Re-investigation of the fragmentation of protonated carotenoids by electrospray ionization and nanospray tandem mass spectrometry 10.1002/rcm.7589

Metabolomics method to comprehensively analyze amino acids in different domains 10.1039/c4an02386b

Chrysobalanaceae: secondary metabolites, ethnopharmacology and pharmacological potential 10.1007/s11101-012-9259-z

Dereplication of Phenolic Derivatives of Qualea grandiflora and Qualea cordata (Vochysiaceae) using Liquid Chromatography coupled with ESI-QToF-MS/MS 10.5935/0103-5053.20130098

Interval Multivariate Curve Resolution in the Dereplication of HPLC-DAD Data from Jatropha gossypifolia 10.1002/pca.2423

Vochysiaceae: secondary metabolites, ethnopharmacology and pharmacological potential 10.1007/s11101-011-9213-5

Quantitative Method to Investigate the Balance between Metabolism and Proteome Biomass: Starting from Glycine 10.1002/anie.201609236

An integrative omics perspective for the analysis of chemical signals in ecological interactions 10.1039/C7CS00368D

Chemical profiling of two congeneric sea mat corals along the Brazilian coast: adaptive and functional patterns 10.1039/C7CC08411K

Characterization of aporphine alkaloids by electrospray ionization tandem mass spectrometry and density functional theory calculations 10.1002/rcm.8533

Mass Spectral Similarity Networking and Gas-Phase Fragmentation Reactions in the Structural Analysis of Flavonoid Glycoconjugates 10.1021/acs.analchem.8b05479

Correction to Mass Spectral Similarity Networking and Gas-Phase Fragmentation Reactions in the Structural Analysis of Flavonoid Glycoconjugates 10.1021/acs.analchem.9b04825

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Metabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate Biosynthesis 10.1161/circresaha.119.315483

RAMSY: Ratio Analysis of Mass Spectrometry to Improve Compound Identification 10.1021/ac4019268

Patent analysis: a look at the innovative nature of plant-based cosmetics 10.21577/0100-4042.20170022

Plant Metabolomics Using NMR Spectroscopy 10.1007/978-1-4939-9690-2_19

Characteristic product ions of acetylene carotenoids by electrospray and nanospray ionization tandem mass spectrometry 10.1002/rcm.8811

Effect of a Flaxseed Lignan Intervention on Circulating Bile Acids in a Placebo-Controlled Randomized, Crossover Trial 10.3390/nu12061837

Glucocerebrosidase reduces the spread of protein aggregation in a Drosophila melanogaster model of neurodegeneration by regulating proteins trafficked by extracellular vesicles 10.1371/journal.pgen.1008859

Formation of sodium cluster ions complicates liquid chromatography–mass spectrometry metabolomics analyses 10.1002/rcm.9175

Expanding Urinary Metabolite Annotation through Integrated Mass Spectral Similarity Networking 10.1021/acs.analchem.1c02041

Duy Vo

Vo Duy

ORCID: 0000-0001-8789-5350

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Joseph Egan

Egan Joseph

ORCID: 0000-0002-6836-2361

A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition 10.1371/journal.pone.0124814

Comparison of the chemistry and diversity of endophytes isolated from wild-harvested and greenhouse-cultivated yerba mansa (Anemopsis californica) 10.1016/j.phytol.2014.12.013

Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds 10.1021/acs.jnatprod.5b01014

Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis) 10.1016/j.phytol.2016.07.031

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research 10.1039/c7np00064b

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Bacterial efflux inhibitors are widely distributed in land plants 10.1016/j.jep.2020.113533

Development of an NMR-Based Platform for the Direct Structural Annotation of Complex Natural Products Mixtures. 10.1021/acs.jnatprod.0c01076

Ram Neupane

Neupane Ram

ORCID: 0000-0002-9310-7426

Email: neupane@hawaii.edu

Tetra(Acetato)Dichromium(II) Dihydrate 10.1002/9781118744994.ch38

Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells 10.1038/s41598-017-18996-2

Enantioselective Hydroformylation ofN-Vinyl Carboxamides, Allyl Carbamates, and Allyl Ethers Using Chiral Diazaphospholane Ligands 10.1021/ja106674n

Synthesis and Characterization of a Layered Manganese Oxide: Materials Chemistry for the Inorganic or Instrumental Methods Lab 10.1021/ed083p1674

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research 10.1039/c7np00064b

Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge Dactylospongia elegans 10.3390/md17070423

Myrmenaphthol A, Isolated from a Hawaiian Sponge of the Genus Myrmekioderma 10.1021/acs.jnatprod.9b00665

Characterization of Leptazolines A–D, Polar Oxazolines from the Cyanobacterium Leptolyngbya sp., Reveals a Glitch with the “Willoughby–Hoye” Scripts for Calculating NMR Chemical Shifts 10.1021/acs.orglett.9b03216

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

David Delgadillo

Delgadillo David / David A. Delgadillo

ORCID: 0000-0002-0897-4470

Copper Binding Sites in the Manganese-Oxidizing Mnx Protein Complex Investigated by Electron Paramagnetic Resonance Spectroscopy 10.1021/jacs.7b02277

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Justin van der Hooft

van der Hooft Justin / Justin J.J. van der Hooft

ORCID: 0000-0002-9340-5511

Structural elucidation of low abundant metabolites in complex sample matrices 10.1007/s11306-013-0519-8

Non-smoky GLYCOSYLTRANSFERASE1 prevents the release of smoky aroma from tomato fruit 10.1105/tpc.113.114231

Automatic chemical structure annotation of an LC-MSn based metabolic profile from green tea 10.1021/ac400861a

Substructure-based annotation of high-resolution multistage MSn spectral trees 10.1002/rcm.6364

Structural annotation and elucidation of conjugated phenolic compounds in black, green, and white tea extracts 10.1021/jf300297y

Structural elucidation and quantification of phenolic conjugates present in human urine after tea intake 10.1021/ac3017339

Spectral trees as a robust annotation tool in LC-MS based metabolomics 10.1007/s11306-011-0363-7

Metabolite identification using automated comparison of high-resolution multistage mass spectral trees 10.1021/ac2034216

Inhibitory activity of plumbagin produced by Drosera intermedia on food spoilage fungi 10.1002/jsfa.5522

A strategy for fast structural elucidation of metabolites in small volume plant extracts using automated MS-guided LC-MS-SPE-NMR 10.1002/mrc.2833

Thermal diffusivity of periderm from tomatoes of different maturity stages as determined by the concept of the frequency-domain open photoacoustic cell 10.1063/1.3530735

Polyphenol identification based on systematic and robust high-resolution accurate mass spectrometry fragmentation 10.1021/ac102546x

Iridoid and caffeoyl phenylethanoid glycosides of the endangered carnivorous plant Pinguicula lusitanica L. (Lentibulariaceae) 10.1016/j.bse.2009.05.003

Topic modeling for untargeted substructure exploration in metabolomics 10.1073/pnas.1608041113

Propagating annotations of molecular networks using in silico fragmentation 10.1371/journal.pcbi.1006089

Did a plant-herbivore arms race drive chemical diversity in Euphorbia? 10.1101/323014

Automatic Compound Annotation from Mass Spectrometry Data Using MAGMa. 10.5702/massspectrometry.S0033

Interactions of blacktea polyphenols with human gut microbiota: implications for gut and cardiovascular health 10.3945/ajcn.113.058263

Identification of a drimenol synthase and drimenol oxidase from Persicaria hydropiper, involved in the biosynthesis of insect deterrent drimanes 10.1111/tpj.13527

Enhanced Acylcarnitine Annotation in High-Resolution Mass Spectrometry Data: Fragmentation Analysis for the Classification and Annotation of Acylcarnitines 10.3389/fbioe.2015.00026

Rapid and sustained systemic circulation of conjugated gut microbiol catabolites after single-dose black tea extract consumption 10.1021/pr5001253

In Silico Prediction and Automatic LC–MSn Annotation of Green Tea Metabolites in Urine 10.1021/ac403875b

Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose 10.1007/s11306-018-1438-5

Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae 10.1101/463620

Deciphering complex metabolite mixtures by unsupervised and supervised substructure discovery and semi-automated annotation from MS/MS spectra 10.1101/491506

Accelerating metabolite identification in natural product research: toward an ideal combination of LC-HRMS/MS and NMR profiling, in silico databases and chemometrics 10.1021/acs.analchem.8b05112

Untargeted Mass Spectrometry-Based Metabolomics Tracks Molecular Changes in Raw and Processed Foods and Beverages 10.1101/347716

Absorption, metabolism, distribution and excretion of (−)-epicatechin: A review of recent findings https://doi.org/10.1016/j.mam.2017.11.002

Metabolite Identification in Complex Mixtures Using Nuclear Magnetic Resonance Spectroscopy 10.1007/978-3-319-28275-6_6-2

Ms2lda.org: web-based topic modelling for substructure discovery in mass spectrometry 10.1093/bioinformatics/btx582

A comprehensive evaluation of the [2-14C](–)-epicatechin metabolome in rats https://doi.org/10.1016/j.freeradbiomed.2016.08.001

The food metabolome: a window over dietary exposure 10.3945/ajcn.113.076133

Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols 10.3945/ajcn.113.058958

Unsupervised Discovery and Comparison of Structural Families Across Multiple Samples in Untargeted Metabolomics 10.1021/acs.analchem.7b01391

A community-driven paired data platform to accelerate natural product mining by combining structural information from genomes and metabolomes 10.18174/FAIRdata2018.16286

Implementations of the chemical structural and compositional similarity metric in R and Python 10.1101/546150

Comprehensive mass spectrometry-guided phenotyping of plant specialized metabolites reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae 10.1111/tpj.14292

A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters 10.1186/s13104-019-4222-3

The Metabolomics Society—Current State of the Membership and Future Directions 10.3390/metabo9050089

Deciphering complex metabolite mixtures by unsupervised and supervised substructure discovery and semi-automated annotation from MS/MS spectra 10.1039/C8FD00235E

MolNetEnhancer: enhanced molecular networks by integrating metabolome mining and annotation tools 10.1101/654459

Substantial extracellular metabolic differences found between phylogenetically closely related probiotic and pathogenic strains of Escherichia coli 10.3389/fmicb.2019.00252

Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia l. 10.3389/fpls.2019.00846

Molnetenhancer: Enhanced molecular networks by integrating metabolome mining and annotation tools 10.3390/metabo9070144

In Silico Optimization of Mass Spectrometry Fragmentation Strategies in Metabolomics 10.3390/metabo9100219

MIBiG 2.0: a repository for biosynthetic gene clusters of known function 10.1093/nar/gkz882

Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages 10.1016/j.foodchem.2019.125290

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Mass spectrometry searches using MASST 10.1038/s41587-019-0375-9

Assessing specialized metabolite diversity of Alnus species by a digitized LC–MS/MS data analysis workflow 10.1016/j.phytochem.2020.112292

Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication 10.1126/sciadv.aax6328

Chemically-informed Analyses of Metabolomics Mass Spectrometry Data with Qemistree 10.1101/2020.05.04.077636

Linking genomics and metabolomics to chart specialized metabolic diversity 10.1039/D0CS00162G

Reproducible molecular networking of untargeted mass spectrometry data using GNPS 10.1038/s41596-020-0317-5

Decomposing metabolite set activity levels with PALS 10.1101/2020.06.07.138974

Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions 10.1101/2020.06.12.148205

Phenylpropane as an Alternative Dearomatizing Unit of Indoles: Discovery of Inaequalisines A and B Using Substructure-Informed Molecular Networking 10.1021/acs.orglett.0c02153

matchms - processing and similarity evaluation of mass spectrometry data 10.1101/2020.08.06.239244

Spec2Vec: Improved mass spectral similarity scoring through learning of structural relationships 10.1101/2020.08.11.245928

BiG-SLiCE: A Highly Scalable Tool Maps the Diversity of 1.2 Million Biosynthetic Gene Clusters 10.1101/2020.08.17.240838

matchms - processing and similarity evaluation of mass spectrometry data. 10.21105/joss.02411

ReDU: a framework to find and reanalyze public mass spectrometry data 10.1038/s41592-020-0916-7

Feature-based molecular networking in the GNPS analysis environment 10.1038/s41592-020-0933-6

Rapid Development of Improved Data-dependent Acquisition Strategies 10.1101/2020.09.11.293092

Chemically informed analyses of metabolomics mass spectrometry data with Qemistree 10.1038/s41589-020-00677-3

Auto-deconvolution and molecular networking of gas chromatography–mass spectrometry data 10.1038/s41587-020-0700-3

The ant fungus garden acts as an external digestive system 10.1101/2020.11.18.389361

BiG-MAP: an automated pipeline to profile metabolic gene cluster abundance and expression in microbiomes 10.1101/2020.12.14.422671

BiG-SLiCE: A highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters 10.1093/gigascience/giaa154

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs 10.1371/journal.ppat.1008932

Comparative Metabologenomics Analysis of Polar Actinomycetes 10.3390/md19020103

Ranking Metabolite Sets by Their Activity Levels 10.3390/metabo11020103

Spec2Vec: Improved mass spectral similarity scoring through learning of structural relationships 10.1371/journal.pcbi.1008724

Rapid Development of Improved Data-Dependent Acquisition Strategies 10.1021/acs.analchem.0c03895

MS2DeepScore - a novel deep learning similarity measure for mass fragmentation spectrum comparisons 10.1101/2021.04.18.440324

Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions 10.1371/journal.pcbi.1008920

Metabolomics-Guided Elucidation of Plant Abiotic Stress Responses in the 4IR Era: An Overview 10.3390/metabo11070445

Chemical Gradients of Plant Substrates in an Atta texana Fungus Garden 10.1128/mSystems.00601-21

Comprehensive Large-Scale Integrative Analysis of Omics Data To Accelerate Specialized Metabolite Discovery 10.1128/mSystems.00726-21

Laia Castaño-Espriu

Castaño-Espriu Laia

ORCID: 0000-0002-8222-1629

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Bioassay- and metabolomics-guided screening of bioactive soil actinomycetes from the ancient city of Ihnasia, Egypt 10.1371/journal.pone.0226959

Advances in actinomycete research: an ActinoBase review of 2019 10.1099/mic.0.000944

Catherine S. McCaughey

McCaughey Catherine S.

ORCID: 0000-0002-5967-4654

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Isolation, Structure Elucidation, and Total Synthesis of Dolichovespulide, a Sesquiterpene from Dolichovespula Yellowjackets 10.1021/acs.jnatprod.9b00238

Maculatic Acids-Sex Attractant Pheromone Components of Bald-Faced Hornets 10.1002/ange.201804666

Alison Hughes

Hughes Alison / Ally Hughes

ORCID: 0000-0002-9670-0663

http://www.medicinesfromthesea.com/lab-members.html

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

XVI International Symposium on Marine Natural Products|XI European Conference on Marine Natural Products 10.3390/md18010040

Exploring the Chemical Space of Macro- and Micro-Algae Using Comparative Metabolomics 10.3390/microorganisms9020311

Comparative Metabologenomics Analysis of Polar Actinomycetes 10.3390/md19020103

Victor Aniebok

Aniebok Victor

ORCID: 0000-0002-9309-4725

Synthesis and Investigation of the Abiotic Formation of Pyonitrins A–D 10.1021/acs.orglett.0c00098

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Marnix H. Medema

Medema Marnix H.

ORCID: 0000-0002-2191-2821

http://www.marnixmedema.nl

antiSMASH 10.1007/978-1-4899-7478-5_703

Bioinformatics Approaches and Software for Detection of Secondary Metabolic Gene Clusters 10.1007/978-1-62703-122-6_2

Synthetic Biology in Streptomyces Bacteria 10.1016/b978-0-12-385075-1.00021-4

Computational approaches to natural product discovery 10.1038/nchembio.1884

Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms 10.1038/nrmicro2478

A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis 10.1371/journal.pcbi.1004016

Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism 10.1016/j.febslet.2011.06.014

MultiMetEval: Comparative and Multi-Objective Analysis of Genome-Scale Metabolic Models 10.1371/journal.pone.0051511

The future of industrial antibiotic production: From random mutagenesis to synthetic biology 10.4161/bbug.2.4.16114

Metabolomics methods for the synthetic biology of secondary metabolism 10.1016/j.febslet.2012.02.008

Computational tools for the synthetic design of biochemical pathways 10.1038/nrmicro2717

A predicted physicochemically distinct sub-proteome associated with the intracellular organelle of the anammox bacterium Kuenenia stuttgartiensis 10.1186/1471-2164-11-299

Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus 10.1111/j.1751-7915.2010.00226.x

Denitrifying bacteria anaerobically oxidize methane in the absence of Archaea 10.1111/j.1462-2920.2008.01724.x

Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters 10.1016/j.cell.2014.06.034

Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products 10.1371/journal.pcbi.1003822

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters 10.1093/nar/gkv437

Design-based re-engineering of biosynthetic gene clusters: plug-and-play in practice 10.1016/j.copbio.2013.03.006

Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block 10.1021/sb500368w

antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers 10.1093/nar/gkt449

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences 10.1093/nar/gkr466

The Sequence of a 1.8-Mb Bacterial Linear Plasmid Reveals a Rich Evolutionary Reservoir of Secondary Metabolic Pathways 10.1093/gbe/evq013

MS/MS networking guided analysis of molecule and gene cluster families 10.1073/pnas.1303471110

Detecting Sequence Homology at the Gene Cluster Level with MultiGeneBlast 10.1093/molbev/mst025

Complete Genome Sequence of the Frog Pathogen Mycobacterium ulcerans Ecovar Liflandii 10.1128/jb.02132-12

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity 10.1093/nar/gkr323

Mechanisms and Evolution of Control Logic in Prokaryotic Transcriptional Regulation 10.1128/mmbr.00037-08

Genomic mutational analysis of the impact of the classical strain improvement program on β-lactam producing Penicillium chrysogenum. 10.1186/s12864-015-2154-4

Leucanicidin and endophenasides result from methyl-rhamnosylation by the same tailoring enzymes in Kitasatospora sp. MBT66 10.1021/acschembio.5b00801

Computational strategies for genome-based natural product discovery and engineering in fungi 10.1016/j.fgb.2016.01.006

The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters 10.1093/nar/gkw960

Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides 10.1038/nmicrobiol.2016.197

Editorial: Synthetic biology and bioinformatics 10.1039/c6np90031c

plantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters 10.1093/nar/gkx305

Genome-based exploration of the specialized metabolic capacities of the genus Rhodococcus 10.1186/s12864-017-3966-1

Mining prokaryotes for antimicrobial compounds: from diversity to function 10.1093/femsre/fux014

Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters 10.1093/bib/bbx146

Standardization for natural product synthetic biology 10.1039/c6np00030d

Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways 10.1039/c6np00035e

Draft Genome Sequence of a Porcine Commensal, Rothia nasimurium , Encoding a Nonribosomal Peptide Synthetase Predicted To Produce the Ionophore Antibiotic Valinomycin 10.1128/genomea.00453-17

SANDPUMA: ensemble predictions of nonribosomal peptide chemistry reveal biosynthetic diversity across Actinobacteria 10.1093/bioinformatics/btx400

Collaborating with Undergraduates To Contribute to Biochemistry Community Resources 10.1021/acs.biochem.7b00872

Road MAPs to engineer host microbiomes. 10.1016/j.mib.2017.11.023

Genome-wide analysis of bacterial determinants of plant growth promotion and induced systemic resistance by Pseudomonas fluorescens. 10.1111/1462-2920.13927

Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution. 10.1073/pnas.1705567114

antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification. 10.1093/nar/gkx319

Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products. 10.1016/j.fgb.2016.01.012

Exploration and exploitation of the environment for novel specialized metabolites. 10.1016/j.copbio.2018.01.017

Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology 10.1128/mSystems.00182-17

Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics. 10.1016/j.chembiol.2018.02.008

HEx: A heterologous expression platform for the discovery of fungal natural products. 10.1126/sciadv.aar5459

luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria. 10.1128/msystems.00208-17

A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology. 10.1021/jacs.7b13292

Evolution and Diversity of Biosynthetic Gene Clusters in Fusarium. 10.3389/fmicb.2018.01158

Involvement of Burkholderiaceae and sulfurous volatiles in disease-suppressive soils. 10.1038/s41396-018-0186-x

Genomic Identification and Analysis of Specialized Metabolite Biosynthetic Gene Clusters in Plants Using PlantiSMASH. 10.1007/978-1-4939-7874-8_15

A standardized workflow for submitting data to the Minimum Information about a Biosynthetic Gene cluster (MIBiG) repository: prospects for research-based educational experiences 10.1186/s40793-018-0318-y

The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters 10.1093/nar/gky1060

Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae 10.1101/463620

Mining bacterial genomes to reveal secret synergy 10.1074/jbc.H118.006669

Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters 10.1038/s42003-019-0333-6

Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae 10.1111/tpj.14292

A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters 10.1186/s13104-019-4222-3

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline 10.1093/nar/gkz310

MolNetEnhancer: enhanced molecular networks by integrating metabolome mining and annotation tools 10.1101/654459

BiosyntheticSPAdes: Reconstructing Biosynthetic Gene Clusters From Assembly Graphs 10.1101/gr.243477.118

Genome Mining Approaches to Bacterial Natural Product Discovery 10.1016/b978-0-12-409547-2.14627-x

Computer-aided re-engineering of nonribosomal peptide and polyketide biosynthetic assembly lines 10.1039/C9NP00021F

PlantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters 10.1101/083535

MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools 10.3390/metabo9070144

Assessing Specialized Metabolite Diversity in the Cosmopolitan Plant Genus Euphorbia L. 10.3389/fpls.2019.00846

Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome 10.1126/science.aaw9285

MIBiG 2.0: a repository for biosynthetic gene clusters of known function 10.1093/nar/gkz882

A metabolic pathway for bile acid dehydroxylation by the gut microbiome 10.1101/758557

Coevolution-based prediction of protein-protein interactions in polyketide biosynthetic assembly lines 10.1101/669291

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Cultivation and functional characterization of 79 planctomycetes uncovers their unique biology 10.1038/s41564-019-0588-1

Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia 10.1101/856955

Drivers of metabolic diversification: how dynamic genomic neighbourhoods generate new biosynthetic pathways in the Brassicaceae 10.1111/nph.16338

Microbial and volatile profiling of soils suppressive to Fusarium culmorum of wheat 10.1098/rspb.2019.2527

Computational genomic discovery of diverse gene clusters harboring Fe-S flavoenzymes in anaerobic gut microbiota 10.1101/2020.03.06.976126

RRE-Finder: A Genome-Mining Tool for Class-Independent RiPP Discovery 10.1101/2020.03.14.992123

Linking genomics and metabolomics to chart specialized metabolic diversity 10.1039/D0CS00162G

Computational genomic discovery of diverse gene clusters harbouring Fe-S flavoenzymes in anaerobic gut microbiota 10.1099/mgen.0.000373

ARTS 2.0: feature updates and expansion of the Antibiotic Resistant Target Seeker for comparative genome mining 10.1093/nar/gkaa374

Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products 10.1101/2020.05.19.104752

Ecology and genomics of Actinobacteria: new concepts for natural product discovery 10.1038/s41579-020-0379-y

The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms 10.1038/s42003-020-0993-2

BiG-SLiCE: A Highly Scalable Tool Maps the Diversity of 1.2 Million Biosynthetic Gene Clusters 10.1101/2020.08.17.240838

Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia 10.1074/jbc.RA120.013528

Microbial natural product databases: moving forward in the multi-omics era 10.1039/D0NP00053A

Author Correction: The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms 10.1038/s42003-020-01228-1

RRE-Finder: a Genome-Mining Tool for Class-Independent RiPP Discovery 10.1128/mSystems.00267-20

Author Correction: The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms 10.1038/s42003-020-01271-y

BiG-FAM: the biosynthetic gene cluster families database 10.1093/nar/gkaa812

Coevolution-based prediction of protein–protein interactions in polyketide biosynthetic assembly lines 10.1093/bioinformatics/btaa595

The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes 10.1093/nar/gkaa978

Pan-genome analysis and ancestral state reconstruction of class halobacteria: probability of a new super-order 10.1038/s41598-020-77723-6

BiG-MAP: an automated pipeline to profile metabolic gene cluster abundance and expression in microbiomes 10.1101/2020.12.14.422671

Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides 10.1371/journal.pbio.3001026

BiG-SLiCE: A highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters 10.1093/gigascience/giaa154

The year 2020 in natural product bioinformatics: an overview of the latest tools and databases 10.1039/D0NP00090F

Do size and shape matter? Exploring the interactions and the metabolome of the soil isolate Hylemonella gracilis 10.1101/2021.02.11.430889

A systematic analysis of metabolic pathways in the human gut microbiota 10.1101/2021.02.25.432841

Omics-based strategies to discover novel classes of RiPP natural products 10.1016/j.copbio.2020.12.008

Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria 10.1038/s41467-021-21163-x

The Surfactin-Like Lipopeptides From Bacillus spp.: Natural Biodiversity and Synthetic Biology for a Broader Application Range 10.3389/fbioe.2021.623701

Mining metagenomes for natural product biosynthetic gene clusters: unlocking new potential with ultrafast techniques 10.1101/2021.01.20.427441

Extracting the GEMs: Genotype, Environment, and Microbiome Interactions Shaping Host Phenotypes 10.3389/fmicb.2020.574053

A mammalian commensal of the oropharyngeal cavity produces antibiotic and antiviral valinomycin in vivo 10.21203/rs.3.rs-126949/v1

A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters 10.1016/j.chembiol.2020.11.009

cblaster: a remote search tool for rapid identification and visualisation of homologous gene clusters 10.1101/2020.11.08.370601

antiSMASH 6.0: improving cluster detection and comparison capabilities 10.1093/nar/gkab335

The gutSMASH web server: automated identification of primary metabolic gene clusters from the gut microbiota 10.1093/nar/gkab353

Mining genomes to illuminate the specialized chemistry of life 10.1038/s41576-021-00363-7

Dominant drivers of the human plasma metabolome 10.21203/rs.3.rs-688716/v1

A global survey of specialized metabolic diversity encoded in bacterial genomes 10.1101/2021.08.11.455920

cblaster: a remote search tool for rapid identification and visualization of homologous gene clusters 10.1093/bioadv/vbab016

Timothy O'Donnell

O'Donnell Timothy / Timothy J. O'Donnell

ORCID: 0000-0003-0291-8838

6-Deoxy- and 11-Hydroxytolypodiols: Meroterpenoids from the Cyanobacterium HT-58-2 10.1021/acs.jnatprod.9b00844

P-Alkynyl functionalized benzazaphospholes as transmetalating agents 10.1039/D0DT01367F

Tolyporphins L-R: Unusual Tetrapyrroles from a Brasilonema sp. of Cyanobacterium. 10.1021/acs.joc.9b01928

Production and excretion of astaxanthin by engineered Yarrowia lipolytica using plant oil as both the carbon source and the biocompatible extractant. 10.1007/s00253-020-10753-2

Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosis 10.1371/journal.ppat.1009570

Tolyporphins A–R, unusual tetrapyrrole macrocycles in a cyanobacterium from Micronesia, assessed quantitatively from the culture HT-58-2 10.1039/D1NJ02108G

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

E-Selective Synthesis and Coordination Chemistry of Pyridine-Phosphaalkenes: Five Ligands Produce Four Distinct Types of Ru(II) Complexes 10.1021/acs.organomet.9b00425

Katherine R. Duncan

Duncan Katherine R. / Katherine Duncan

ORCID: 0000-0002-3670-4849

http://www.sams.ac.uk/katherine-duncan

https://pureportal-staging.strath.ac.uk/en/persons/167c635b-502a-4b45-8e2b-ef1d219a7d47

Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from salinispora species 10.1016/j.chembiol.2015.03.010

Exploring the diversity and metabolic potential of actinomycetes from temperate marine sediments from Newfoundland, Canada 10.1007/s10295-014-1529-x

Bioprospecting from marine sediments of New Brunswick, Canada 10.3390/md12020899

An integrative approach to decipher the chemical antagonism between the competing endophytes paraconiothyrium variabile and Bacillus subtilis 10.1021/acs.jnatprod.6b01185

Chemical dereplication of marine actinomycetes by liquid chromatography-high resolution mass spectrometry profiling and statistical analysis 10.1016/j.aca.2013.10.029

Antagonistic interactions mediated by marine bacteria 10.1007/s10886-013-0316-x

Using molecular networking for microbial secondary metabolite bioprospecting 10.3390/metabo6010002

Competitive strategies differentiate closely related species of marine actinobacteria 10.1038/ismej.2015.128

Temperature driven changes in benthic bacterial diversity influences biogeochemical cycling in coastal sediments 10.3389/fmicb.2018.01730

Linking biosynthetic and chemical space to accelerate microbial secondary metabolite discovery 10.1093/femsle/fnz142

Awakening ancient polar actinobacteria 10.1099/mic.0.000845

The Natural Products Atlas 10.1021/acscentsci.9b00806

Bioassay- and metabolomics-guided screening of bioactive soil actinomycetes from the ancient city of Ihnasia, Egypt 10.1371/journal.pone.0226959

Linking genomics and metabolomics to chart specialized metabolic diversity 10.1039/D0CS00162G

Exploring the Chemical Space of Macro- and Micro-Algae Using Comparative Metabolomics 10.3390/microorganisms9020311

Comparative metabologenomics analysis of polar actinomycetes 10.3390/md19020103

Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions 10.1371/journal.pcbi.1008920

Katherine Zink

Zink Katherine

ORCID: 0000-0002-7886-9887

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Pseudomonas aeruginosa PumA acts on an endogenous phenazine to promote self-resistance 10.1099/mic.0.000657

Imaging Mass Spectrometry Reveals Crosstalk between the Fallopian Tube and the Ovary that Drives Primary Metastasis of Ovarian Cancer 10.1021/acscentsci.8b00405

Optimization of a minimal sample preparation protocol for imaging mass spectrometry of unsectioned juvenile invertebrates 10.1002/jms.4458

Capturing small molecule communication between tissues and cells using imaging mass spectrometry 10.3791/59490

Calling All Hosts: Bacterial Communication In Situ 10.1016/j.chempr.2017.02.001

Fallopian Tube-Derived Tumor Cells Induce Testosterone Secretion from the Ovary, Increasing Epithelial Proliferation and Invasion 10.3390/cancers13081925

Sanghoon Lee

Lee Sanghoon

ORCID: 0000-0002-1377-3913

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Agelamasines A and B, diterpene alkaloids from an Okinawan marine sponge Agelas sp. 10.1007/s11418-017-1157-7

Neuroprotective Compounds from Salix pseudo-lasiogyne Twigs and Their Anti-Amnesic Effects on Scopolamine-Induced Memory Deficit in Mice 10.1055/s-0032-1327949

Salicortin-Derivatives from Salix pseudo-lasiogyne Twigs Inhibit Adipogenesis in 3T3-L1 Cells via Modulation of C/EBPα and SREBP1c Dependent Pathway 10.3390/molecules180910484

Agesasines A and B, Bromopyrrole Alkaloids from Marine Sponges Agelas spp 10.3390/md18090455

Fred "Jake" Haeckl

Haeckl Fred "Jake" / F.P. Jake Haeckl / Jake Haeckl

ORCID: 0000-0002-2776-5957

Optimized quinoline amino alcohols as disruptors and dispersal agents of Vibrio cholerae biofilms 10.1039/c5ob01134e

Lipopeptides from the Tropical Marine CyanobacteriumSymplocasp. 10.1021/np401051z

Isolation and Structure Elucidation of Three New Lipopeptides from the Marine Cyanobacterium Symploca sp. 10.1055/s-0033-1348536

Total Synthesis of Skyllamycins A–C 10.1002/chem.201704277

Synthetic Studies Toward the Skyllamycins: Total Synthesis and Generation of Simplified Analogues 10.1021/acs.joc.8b00898

A selective genome-guided method for environmental Burkholderia isolation 10.1007/s10295-018-02121-x

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Development of a Custom MALDI-TOF Mass Spectrometric Database for Identification of Environmental Burkholderia and Related Genera. 10.1128/aem.00354-20

Total synthesis of biselide A 10.1039/D0SC06223E

Roger Linington

Linington Roger / Roger G. Linington

ORCID: 0000-0003-1818-4971

http://linington.chem.sfu.ca/

Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids. 10.1371/journal.pone.0149603

The Natural Product N-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human Spliceosomes. 10.1074/jbc.M115.673210

Integration of high-content screening and untargeted metabolomics for comprehensive functional annotation of natural product libraries. 10.1073/pnas.1507743112

Phenotype-Guided Natural Products Discovery Using Cytological Profiling. 10.1021/acs.jnatprod.5b00455

Genome-Directed Lead Discovery: Biosynthesis, Structure Elucidation, and Biological Evaluation of Two Families of Polyene Macrolactams against Trypanosoma brucei. 10.1021/acschembio.5b00308

Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta. 10.1021/acs.joc.5b01264

Optimized quinoline amino alcohols as disruptors and dispersal agents of Vibrio cholerae biofilms. 10.1039/c5ob01134e

Living in the matrix: assembly and control of Vibrio cholerae biofilms. 10.1038/nrmicro3433

Connecting phenotype and chemotype: high-content discovery strategies for natural products research. 10.1021/acs.jnatprod.5b00017

Salinipostins A-K, long-chain bicyclic phosphotriesters as a potent and selective antimalarial chemotype. 10.1021/jo5024409

Abyssomicin 2 reactivates latent HIV-1 by a PKC- and HDAC-independent mechanism. 10.1021/ol503349y

Development of benzo[1,4]oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae. 10.1039/c4cc07003h

Borrelidin B: isolation, biological activity, and implications for nitrile biosynthesis. 10.1021/np500727g

A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. 10.1016/j.cell.2014.08.032

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters. 10.1016/j.cell.2014.06.034

Sloth hair as a novel source of fungi with potent anti-parasitic, anti-cancer and anti-bacterial bioactivity. 10.1371/journal.pone.0084549

An NF-κB-based high-throughput screen identifies piericidins as inhibitors of the Yersinia pseudotuberculosis type III secretion system. 10.1128/AAC.02025-13

Image-based 384-well high-throughput screening method for the discovery of skyllamycins A to C as biofilm inhibitors and inducers of biofilm detachment in Pseudomonas aeruginosa. 10.1128/AAC.01781-13

MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus. 10.1038/ja.2013.99

Discovery and biological characterization of the auromomycin chromophore as an inhibitor of biofilm formation in Vibrio cholerae. 10.1002/cbic.201300131

Molecular networking as a dereplication strategy. 10.1021/np400413s

Mechanism of action-based classification of antibiotics using high-content bacterial image analysis. 10.1039/c3mb70027e

Development of quinoline-based disruptors of biofilm formation against Vibrio cholerae. 10.1021/ol400150z

Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei. 10.1021/np300834q

"Function-first" lead discovery: mode of action profiling of natural product libraries using image-based screening. 10.1016/j.chembiol.2012.12.007

Development of antibiotic activity profile screening for the classification and discovery of natural product antibiotics. 10.1016/j.chembiol.2012.09.014

Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP. 10.1016/j.chembiol.2012.08.014

Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness. 10.1371/journal.pone.0046172

Chemical inhibitors of the type three secretion system: disarming bacterial pathogens. 10.1128/AAC.00975-12

Examining the fish microbiome: vertebrate-derived bacteria as an environmental niche for the discovery of unique marine natural products. 10.1371/journal.pone.0035398

Total synthesis, stereochemical assignment, and antimalarial activity of gallinamide A. 10.1002/chem.201102538

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds. 10.1038/nchembio.664

Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants. 10.1016/j.bmc.2011.07.017

Versatile method for the detection of covalently bound substrates on solid supports by DART mass spectrometry. 10.1021/ol201404v

Expedient synthesis of α,α-dimethyl-β-hydroxy carbonyl scaffolds via Evans' aldol reaction with a tertiary enolate. 10.1016/j.tetlet.2011.03.126

An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae. 10.1039/c0mb00276c

Identification and characterization of a phosphodiesterase that inversely regulates motility and biofilm formation in Vibrio cholerae. 10.1128/JB.00209-10

Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds. 10.1021/jm100265s

Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity. 10.1021/np900622m

Dereplication and de novo sequencing of nonribosomal peptides. 10.1038/nmeth.1350

New innovations for an old infection: antimalarial lead discovery from marine natural products during the period 2003-2008. 10.4155/fmc.09.56

Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides. 10.1021/ac900114t

Antimalarial peptides from marine cyanobacteria: isolation and structural elucidation of gallinamide A. 10.1021/np8003529

Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp. 10.1021/np070280x

Linking bioprospecting with sustainable development and conservation: the Panama case 10.1007/s10531-007-9214-2

Antimalarial linear lipopeptides from a Panamanian strain of the marine cyanobacterium Lyngbya majuscula. 10.1021/np0700772

Venturamides A and B: antimalarial constituents of the panamanian marine Cyanobacterium Oscillatoria sp. 10.1021/np0605790

Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. 10.1021/np050192h

Stereochemical assignment in acyclic lipids across long distance by circular dichroism: absolute stereochemistry of the aglycone of caminoside A. 10.1002/anie.200461158

Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri: structure elucidation, synthesis, and biogenetic implications. 10.1021/ol034950b

Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia. 10.1021/ol0268337

Total Synthesis of Glycinocins A-C. 10.1021/acs.joc.7b01959

Total Synthesis of Skyllamycins A-C. 10.1002/chem.201704277

Data-analysis strategies for image-based cell profiling. 10.1038/nmeth.4397

Reply to Skinnider and Magarvey: Rates of novel natural product discovery remain high. 10.1073/pnas.1711139114

Retrospective analysis of natural products provides insights for future discovery trends. 10.1073/pnas.1614680114

Special Issue in Honor of Professor Phil Crews. 10.1021/acs.jnatprod.7b00161

Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. 10.1038/ncomms14414

Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly. 10.1128/msphere.00030-17

Discovery of anabaenopeptin 679 from freshwater algal bloom material: Insights into the structure-activity relationship of anabaenopeptin protease inhibitors. 10.1016/j.bmcl.2016.09.008

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. 10.1038/nbt.3597

Erratum for Duncan et al., An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System. 10.1128/aac.00973-16

Image-Based Screening Approaches to Natural Products Discovery 10.1002/9781118794623.ch20

De Novo Sequencing of Nonribosomal Peptides 10.1007/978-3-540-78839-3_16

De Novo terpenoid biosynthesis by the dendronotid nudibranch Melibe leonina 10.1007/pl00012669

The bioactive lipid (S)-sebastenoic acid impacts motility and dispersion in Vibrio cholerae 10.1139/cjc-2017-0334

Synthetic Studies Toward the Skyllamycins: Total Synthesis and Generation of Simplified Analogues 10.1021/acs.joc.8b00898

Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against Clostridium difficile. 10.1021/acsinfecdis.7b00105

A selective genome-guided method for environmental Burkholderia isolation. 10.1007/s10295-018-02121-x

Genome-Based Identification of a Plant-Associated Marine Bacterium as a Rich Natural Product Source. 10.1002/anie.201805673

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. 10.1039/c7np00064b

Synthesis and evaluation of analogues of the glycinocin family of calcium-dependent antibiotics. 10.1039/c8ob01268g

Maculatic Acids-Sex Attractant Pheromone Components of Bald-Faced Hornets. 10.1002/anie.201804666

Cutibacterium acnes antibiotic production shapes niche competition in the human skin microbiome 10.1101/594010

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. 10.1039/c8np90041h

Problems in Organic Structure Determination 10.1201/b19329

MIBiG 2.0: a repository for biosynthetic gene clusters of known function 10.1093/nar/gkz882

High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling 10.1101/748129

Isolation, Structure Elucidation, and Total Synthesis of Dolichovespulide, a Sesquiterpene from Dolichovespula Yellowjackets 10.1021/acs.jnatprod.9b00238

Targeting tRNA-Synthetase Interactions towards Novel Therapeutic Discovery Against Eukaryotic Pathogens 10.1101/711697

New methods for isolation and structure determination of natural products 10.1039/c9np90023c

Development of a Custom MALDI-TOF Mass Spectrometric Database for Identification of Environmental Burkholderia and Related Genera. 10.1128/aem.00354-20

Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogens. 10.1371/journal.pntd.0007983

The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites. 10.1016/j.chembiol.2020.01.001

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery. 10.1021/acscentsci.9b00806

A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles 10.1126/scitranslmed.aay5445

Expansion of Gamma-Butyrolactone Signaling Molecule Biosynthesis to Phosphotriester Natural Products. 10.1021/acschembio.0c00824

Microbial natural product databases: moving forward in the multi-omics era. 10.1039/d0np00053a

Laura Sanchez

Sanchez Laura

ORCID: 0000-0001-9223-7977

http://www.sanchezlab.science/

Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids 10.1371/journal.pone.0149603

Microbiota of Healthy Corals Are Active against Fungi in a Light-Dependent Manner 10.1021/cb500432j

Mass spectrometry of natural products: current, emerging and future technologies 10.1039/c4np00044g

Versatile Method for the Detection of Covalently Bound Substrates on Solid Supports by DART Mass Spectrometry 10.1021/ol201404v

Almiramides A−C: Discovery and Development of a New Class of Leishmaniasis Lead Compounds 10.1021/jm100265s

Examination of the Mode of Action of the Almiramide Family of Natural Products against the Kinetoplastid Parasite Trypanosoma brucei 10.1021/np300834q

Molecular Networking as a Dereplication Strategy 10.1021/np400413s

Examining the Fish Microbiome: Vertebrate-Derived Bacteria as an Environmental Niche for the Discovery of Unique Marine Natural Products 10.1371/journal.pone.0035398

Analytical chemistry: Virulence caught green-handed 10.1038/nchem.1583

Ralstonia solanacearum lipopeptide induces chlamydospore development in fungi and facilitates bacterial entry into fungal tissues 10.1038/ismej.2016.32

Real-Time Metabolomics on Living Microorganisms Using Ambient Electrospray Ionization Flow-Probe 10.1021/ac401613x

An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria 10.1128/msystems.00028-15

Pyrroloacridine Alkaloids from Plakortis quasiamphiaster : Structures and Bioactivity 10.1021/np060585w

Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides 10.1038/nmicrobiol.2016.197

Spatial Molecular Architecture of the Microbial Community of a Peltigera Lichen 10.1128/msystems.00139-16

Calling All Hosts: Bacterial Communication In Situ 10.1016/j.chempr.2017.02.001

Coproporphyrin III Produced by the Bacterium Glutamicibacter arilaitensis Binds Zinc and Is Upregulated by Fungi in Cheese Rinds. 10.1128/mSystems.00036-18

Imaging Mass Spectrometry Reveals Crosstalk between the Fallopian Tube and the Ovary that Drives Primary Metastasis of Ovarian Cancer. 10.1021/acscentsci.8b00405

Whole Cell MALDI Fingerprinting Is a Robust Tool for Differential Profiling of Two-Component Mammalian Cell Mixtures. 10.1007/s13361-018-2088-6

Capturing Small Molecule Communication Between Tissues and Cells Using Imaging Mass Spectrometry. 10.3791/59490

BLANKA: an Algorithm for Blank Subtraction in Mass Spectrometry of Complex Biological Samples. 10.1007/s13361-019-02185-8

Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data. 10.3791/59219

Staring into the void: demystifying microbial metabolomics. 10.1093/femsle/fnz135

Minimizing Taxonomic and Natural Product Redundancy in Microbial Libraries Using MALDI-TOF MS and the Bioinformatics Pipeline IDBac. 10.1021/acs.jnatprod.9b00168

Optimization of a minimal sample preparation protocol for imaging mass spectrometry of unsectioned juvenile invertebrates 10.1002/jms.4458

Chemically transformed monolayers on acene thin films for improved metal/organic interfaces 10.1039/c9cc07234a

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806

Biofilm Inhibitor Taurolithocholic Acid Alters Colony Morphology, Specialized Metabolism, and Virulence of Pseudomonas aeruginosa 10.1021/acsinfecdis.9b00424

Detection of Ovarian Cancer Using Samples Sourced from the Vaginal Microenvironment 10.1021/acs.jproteome.9b00694

A Call to Action: the Need for Standardization in Developing Open-Source Mass Spectrometry-Based Methods for Microbial Subspecies Discrimination 10.1128/msystems.00813-19

Addition of insoluble fiber to isolation media allows for increased metabolite diversity of lab-cultivable microbes derived from zebrafish gut samples 10.1080/19490976.2020.1740073

Imaging mass spectrometry for natural products discovery: a review of ionization methods 10.1039/c9np00038k

Evaluation of Data Analysis Platforms and Compatibility with MALDI-TOF Imaging Mass Spectrometry Data Sets 10.1021/jasms.0c00039

The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells 10.1182/blood.2019004415

Bacterial–fungal interactions revealed by genome-wide analysis of bacterial mutant fitness 10.1038/s41564-020-00800-z

Fallopian Tube-Derived Tumor Cells Induce Testosterone Secretion from the Ovary, Increasing Epithelial Proliferation and Invasion 10.3390/cancers13081925

A Family of Nonribosomal Peptides Modulate Collective Behavior in Pseudovibrio Bacteria Isolated from Marine Sponges** 10.1002/anie.202017320

A community resource for paired genomic and metabolomic data mining 10.1038/s41589-020-00724-z

A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ 10.1128/mbio.03637-20

Models for measuring metabolic chemical changes in the metastasis of high grade serous ovarian cancer: fallopian tube, ovary, and omentum 10.1039/d1mo00074h