Strategies to dissect parasite proteomes
KARL BURGESS
RICHARD BURCHMORE
Parasitology, 2012-8
Richard Burchmore
Burchmore Richard
ORCID: 0000-0003-1663-9004
Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania
10.1016/j.jprot.2016.12.009
Proteomics at the host: pathogen interface
10.3920/978-90-8686-776-9_11
Neuroproteomics
10.1586/epr.10.17
Strategies to dissect parasite proteomes
10.1017/s0031182011002368
Animal Parasitology and Proteomics
10.1002/9780470960660.ch12
Mapping pathways to drug resistance with proteomics
10.1586/14789450.2014.871497
Chemotherapy of Human African Trypanosomiasis
10.2174/1381612023396159
Proteomic insights into parasite biology
10.1017/s0031182012000947
After the genome—where next?
10.1016/s0166-6851(01)00364-4
Leishmania mexicana: promastigotes migrate through osmotic gradients
10.1016/s0014-4894(03)00031-6
Differential in-gel electrophoresis (DIGE) analysis of human bone marrow osteoprogenitor cell contact guidance
10.1016/j.actbio.2008.11.001
Biomarkers of winter disease in gilthead seabream: a proteomics approach
10.3920/978-90-8686-776-9_45
Parasites in the brain? The search for sleeping sickness biomarkers
10.1586/eri.12.124
Sixth Exploratory Measurement Science Group symposium
10.1586/epr.09.88
Identification of anti-infective targets through comparative proteomics
10.1586/14787210.4.2.163
Identification of promoter-binding proteins of the fbp A and C genes in Mycobacterium tuberculosis
10.1016/j.tube.2009.10.001
Alteration in mononuclear cell subpopulations in dogs immunized with gentamicin-attenuated Leishmania infantum
10.1017/s0031182012001187
Proteomics as a tool to explore human milk in health and disease
10.1016/j.jprot.2013.04.008
Functional analysis of Trypanosoma brucei PUF1
10.1016/j.molbiopara.2006.09.007
2D-DIGE proteomic analysis of mesenchymal stem cell cultured on the elasticity-tunable hydrogels
10.1247/csf.12012
Pentose phosphate metabolism in Leishmania mexicana
10.1016/s0166-6851(03)00173-7
The trypanosomiases
10.1016/s0140-6736(03)14694-6
Glucose transport in amastigotes and promastigotes of Leishmania mexicana mexicana
10.1016/0166-6851(95)02485-9
Life in vacuoles – nutrient acquisition by Leishmania amastigotes
10.1016/s0020-7519(01)00259-4
Proteomics in biomarker detection and monitoring of pancreas disease (PD) in atlantic salmon (Salmo salar)
10.3920/978-90-8686-751-6_20
A proteomic analysis of canine serum during the course of babesiosis
10.3920/978-90-8686-776-9_36
The effect of microbial challenge on the intestinal proteome of broiler chickens
10.3920/978-90-8686-776-9_38
The Optimization of Protocols for Proteome Difference Gel Electrophoresis (DiGE) Analysis of Preneoplastic Skin
10.1021/pr0606878
The role of microtopography in cellular mechanotransduction
10.1016/j.biomaterials.2011.11.047
PS 07-14 VASCULAR PROTEIN OXIDATION AND REDOX PROTEOMICS IN HYPERTENSION
10.1097/01.hjh.0000500678.85921.bc
Drug resistance in human African trypanosomiasis
10.2217/fmb.11.88
Research Highlights
10.2217/17435889.3.4.411
Preventing and troubleshooting artefacts in saturation labelled fluorescence 2-D difference gel electrophoresis (saturation DiGE)
10.1002/pmic.201100135
Purine and pyrimidine transport in pathogenic protozoa: From biology to therapy
10.1016/j.femsre.2005.03.004
Identification of ORC1/CDC6-Interacting Factors in Trypanosoma brucei Reveals Critical Features of Origin Recognition Complex Architecture
10.1371/journal.pone.0032674
Pulse of α-2-macroglobulin and lipocalin-1 in the pregnant uterus of European polecats (Mustela putorius) at the time of implantation
10.1101/088609
Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells
10.1016/j.actbio.2010.02.038
Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test
10.1016/s0140-6736(05)66793-1
Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling
10.1016/j.biomaterials.2009.05.040
Enhanced dietary formulation to mitigate winter thermal stress in gilthead sea bream (Sparus aurata): a 2D-DIGE plasma proteome study
10.1007/s10695-016-0315-2
Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection
10.1155/2013/283619
Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echinostoma caproni
10.1017/s0031182011000412
A plethora of targets, a paucity of drugs: progress towards the development of novel chemotherapies for human African trypanosomiasis
10.1586/14787210.1.1.157
Yersinia ruckeri Isolates Recovered from Diseased Atlantic Salmon (Salmo salar) in Scotland Are More Diverse than Those from Rainbow Trout (Oncorhynchus mykiss) and Represent Distinct Subpopulations
10.1128/aem.01173-16
Trypanosoma cruzi contains two galactokinases; molecular and biochemical characterization
10.1016/j.parint.2016.06.008
Prolonged transition time between colostrum and mature milk in a bear, the giant panda,Ailuropoda melanoleuca
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Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome
10.1007/s11306-014-0770-7
Comparative proteomics profiling of a gentamicin-attenuated Leishmania infantum cell line identifies key changes in parasite thiol-redox metabolism
10.1016/j.jprot.2011.11.018
A new erythrose 4-phosphate dehydrogenase coupled assay for transketolase
10.1016/j.jprot.2007.11.002
Identification of developmentally-regulated proteins in Leishmania panamensis by proteome profiling of promastigotes and axenic amastigotes
10.1016/j.molbiopara.2006.01.008
Gentamicin-attenuated Leishmania infantum: A clinicopathological study in dogs
10.1016/j.vetimm.2008.12.002
A fluorescence-based assay for the uptake of CPD0801 (DB829) by African trypanosomes
10.1016/j.molbiopara.2010.07.002
Corrigendum to “Functional analysis of Trypanosoma brucei PUF1” [Mol. Biochem. Parasitol. 150 (2006) 340–349]
10.1016/j.molbiopara.2009.09.003
The chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog
10.1007/s12192-013-0457-4
Identification of immunogenic proteins associated with protection against haemorrhagic septicaemia after vaccination of calves with a live-attenuated aroA derivative of Pasteurella multocida B:2
10.1016/j.rvsc.2009.01.007
‘Transient’ genetic suppression facilitates generation of hexose transporter null mutants in Leishmania mexicana
10.1111/mmi.12106
Predicting the outer membrane proteome of Pasteurella multocida based on consensus prediction enhanced by results integration and manual confirmation
10.1186/1471-2105-13-63
Identification of serum biomarkers in dogs naturally infected with Babesia canis canis using a proteomic approach
10.1186/1746-6148-10-111
Agarose gel serum protein electrophoresis in cats with and without lymphoma and preliminary results of tandem mass fingerprinting analysis
10.1111/j.1939-165x.2011.00310.x
Characterisation of the plasma membrane subproteome of bloodstream formTrypanosoma brucei
10.1002/pmic.200700607
A Molecular Mechanism for Eflornithine Resistance in African Trypanosomes
10.1371/journal.ppat.1001204
Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei
10.1371/journal.pntd.0001618
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics
10.1039/c6mb00239k
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics
10.1039/c6mb00289g
Gentamicin-Attenuated Leishmania infantum Vaccine: Protection of Dogs against Canine Visceral Leishmaniosis in Endemic Area of Southeast of Iran
10.1371/journal.pntd.0002757
Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei
10.1371/journal.pone.0067327
Praziquantel Treatment of Individuals Exposed toSchistosoma haematobiumEnhances Serological Recognition of Defined Parasite Antigens
10.1086/432553
Age‐Related and Infection Intensity–Related Shifts in Antibody Recognition of Defined Protein Antigens in a Schistosome‐Exposed Population
10.1086/589511
Handling Uncertainty in Dynamic Models: The Pentose Phosphate Pathway in Trypanosoma brucei
10.1371/journal.pcbi.1003371
A proteomic approach to assess the host response in gills of farmed Atlantic salmon Salmo salar L. affected by amoebic gill disease
10.1016/j.aquaculture.2016.12.009
A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway
10.1101/gad.570310
Biochemistry and molecular genetics of Leishmania glucose transporters
10.1017/s0031182000075740
Protein Expression of STRO-1 Cells in Response to Different Topographic Features
10.4061/2011/534603
Differential Regulation of Multiple Glucose Transporter Genes in Leishmania mexicana
10.1074/jbc.273.44.29118
Hexose permeation pathways in Plasmodium falciparum-infected erythrocytes
10.1073/pnas.170153097
41 Vascular protein oxidation and redox proteomics in human hypertension
10.1136/heartjnl-2015-308734.41
Sleeping sickness and the brain
10.1007/s00018-002-8472-0
Hexose Transport in Asexual Stages of Plasmodium falciparum and Kinetoplastidae
10.1016/s0169-4758(00)01762-2
The plasma proteome and acute phase proteins of broiler chickens with gait abnormalities
10.3920/978-90-8686-751-6_42
Dogs vaccinated with gentamicin-attenuated Leishmania infantum or infected with wild-type parasite can be distinguished by Western blotting
10.1111/pim.12108
Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications
10.1098/rsif.2009.0177.focus
Proteomic analysis of human osteoprogenitor response to disordered nanotopography
10.1098/rsif.2008.0447
PNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast
10.1074/jbc.m116.714972
Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis
10.1016/j.molbiopara.2012.03.002
The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control
10.1111/mmi.12351
The metabolic enzyme AdhE controls the virulence ofEscherichia coli O157:H7
10.1111/mmi.12651
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics
10.1039/c6mb00290k
Structure of protease-cleavedEscherichia coliα-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment
10.1107/s1399004715008548
Mechanisms of Arsenical and Diamidine Uptake and Resistance in Trypanosoma brucei
10.1128/ec.2.5.1003-1008.2003
Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta
10.1017/s0031182010000028
Vaccination with Recombinant Leishmania donovani Gamma-Glutamylcysteine Synthetase Fusion Protein Protects Against L. donovani Infection
10.1645/ge-2360.1
Multiple Genetic Mechanisms Lead to Loss of Functional TbAT1 Expression in Drug-Resistant Trypanosomes
10.1128/ec.00200-09
A Glucose Transporter Can Mediate Ribose Uptake: DEFINITION OF RESIDUES THAT CONFER SUBSTRATE SPECIFICITY IN A SUGAR TRANSPORTER
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Trypanocidal Furamidine Analogues: Influence of Pyridine Nitrogens on Trypanocidal Activity, Transport Kinetics, and Resistance Patterns
10.1128/aac.01551-10
Outer Membrane Protein A of Bovine and Ovine Isolates of Mannheimia haemolytica Is Surface Exposed and Contains Host Species-Specific Epitopes
10.1128/iai.05469-11
The Trypanocide Diminazene Aceturate Is Accumulated Predominantly through the TbAT1 Purine Transporter: Additional Insights on Diamidine Resistance in African Trypanosomes
10.1128/aac.48.5.1515-1519.2004
Differential proteomics evaluation of osteoprogenitor growth on microgrooved surfaces using bioreactor culture
10.1016/j.cbpa.2007.01.420
Changes in the serum proteome of canine lymphoma identified by electrophoresis and mass spectrometry
10.1016/j.tvjl.2012.12.010
Characterisation of the normal canine serum proteome using a novel electrophoretic technique combined with mass spectrometry
10.1016/j.tvjl.2012.12.011
Enhancing the egg's natural defence against bacterial penetration by increasing cuticle deposition
10.1111/age.12071
Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4
10.1111/j.1365-3024.2010.01270.x
Gentamicin-attenuated Leishmania infantum: cellular immunity production and protection of dogs against experimental canine leishmaniasis
10.1111/j.1365-3024.2010.01237.x
Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules
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A glucose transporter can mediate ribose uptake.: DEFINITION OF RESIDUES THAT CONFER SUBSTRATE SPECIFICITY IN A SUGAR TRANSPORTER.
10.1074/jbc.a110.106815
Loss of the High-Affinity Pentamidine Transporter Is Responsible for High Levels of Cross-Resistance between Arsenical and Diamidine Drugs in African Trypanosomes
10.1124/mol.106.031351
Cloning, Heterologous Expression, and in Situ Characterization of the First High Affinity Nucleobase Transporter from a Protozoan
10.1074/jbc.m301252200
Modulation of the Host Cell Proteome by the Intracellular Apicomplexan Parasite Toxoplasma gondii
10.1128/iai.01115-07
Genetic characterization of glucose transporter function in Leishmania mexicana
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A defined medium for Leishmania culture allows definition of essential amino acids
10.1016/j.exppara.2018.01.009
Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
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The role of membrane transporters in Leishmania virulence
10.1042/etls20170119
The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei
10.1371/journal.pntd.0005626
Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation
10.1098/rsos.161085
Leishmania major H-line attenuated under pressure of gentamicin, induces a Th1 response which protects susceptible BALB/c mice against infection with virulent L. major
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Quantitative proteomic profiling of bovine follicular fluid during follicle development†
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Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection
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Proteomics in Veterinary Medicine
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Rapid changes in Atlantic grey seal milk from birth to weaning – immune factors and indicators of metabolic strain
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181 Nox compartmentalization and protein oxidation in vascular smooth muscle cells – implications in vascular dysfunction in hypertension
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Serum proteome profiling in canine idiopathic dilated cardiomyopathy using TMT-based quantitative proteomics approach
10.1016/j.jprot.2018.03.007
Mix-and-Match Proteomics: Using Advanced Iodoacetyl Tandem Mass Tag Multiplexing To Investigate Cysteine Oxidation Changes with Respect to Protein Expression
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Comparative bioinformatic and proteomic approaches to evaluate the outer membrane proteome of the fish pathogen Yersinia ruckeri
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PROTEOMIC ANALYSIS OF GLYCOSOMES FROM Trypanosoma cruzi EPIMASTIGOTES.
10.1016/j.molbiopara.2019.02.008
Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death.
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Low sulfated heparins target multiple proteins for central nervous system repair.
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Blood serum acute phase proteins and iron dynamics during acute phase response of Salmonella enterica serotype Dublin experimentally infected buffalo calves.
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A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis.
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Vascular Nox (NADPH Oxidase) Compartmentalization, Protein Hyperoxidation, and Endoplasmic Reticulum Stress Response in Hypertension.
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Reference 1D and 2D electrophoresis maps for potential disease related proteins in milk whey from lactating buffaloes and blood serum from buffalo calves (Water buffalo, Bubalus bubalis).
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Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana.
10.1371/journal.ppat.1006953
Identification of novel biomarkers for treatment monitoring in canine leishmaniosis by high-resolution quantitative proteomic analysis.
10.1016/j.vetimm.2017.08.004
Rapid changes in Atlantic grey seal milk from birth to desertion
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Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana.
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The effect of microbial challenge on the intestinal proteome of broiler chickens.
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Correction: Gentamicin-Attenuated Leishmania infantum Vaccine: Protection of Dogs against Canine Visceral Leishmaniosis in Endemic Area of Southeast of Iran.
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Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.
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The serum proteome of Atlantic salmon, Salmo salar, during pancreas disease (PD) following infection with salmonid alphavirus subtype 3 (SAV3).
10.1016/j.jprot.2013.10.016
Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.
10.1074/jbc.M111.233858
Essential roles for deubiquitination in Leishmania life cycle progression
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Mapping the influence of the gut microbiota on small molecules in the brain through mass spectrometry imaging
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The potential of live attenuated vaccines against Cutaneous Leishmaniasis.
10.1016/j.exppara.2020.107849
Multi-Layer Controls of Cas9 Activity Coupled With ATP Synthase Over-Expression for Efficient Genome Editing in Streptomyces.
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Pharmacometabolomics of Meglumine Antimoniate in Patients With Cutaneous Leishmaniasis.
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Mapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U-13C-labelled substrates and LC-MS.
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Glucose-Regulated Protein 78 Interacts with Zika Virus Envelope Protein and Contributes to a Productive Infection
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Essential roles for deubiquitination in Leishmania life cycle progression
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aBravo Is a Novel Aedes aegypti Antiviral Protein That Interacts with, but Acts Independently of, the Exogenous siRNA Pathway Effector Dicer 2
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Effects of Low ω6:ω3 Ratio in Sow Diet and Seaweed Supplement in Piglet Diet on Performance, Colostrum and Milk Fatty Acid Profiles, and Oxidative Status
10.3390/ani10112049
Karl Burgess
Burgess Karl
ORCID: 0000-0002-0881-715X
Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: fragmentation analysis for the classification and annotation of acylcarnitines.
10.3389/fbioe.2015.00026
Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism.
10.1016/j.ijpddr.2013.11.002
Strategies to dissect parasite proteomes.
10.1017/S0031182011002368
Recent advances in liquid and gas chromatography methodology for extending coverage of the metabolome
10.1016/j.copbio.2016.09.006
A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms
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MetaboCraft: building a Minecraft plugin for metabolomics
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Minimally-destructive atmospheric ionisation mass spectrometry authenticates authorship of historical manuscripts
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Plasma Itaconate elevation following successful cDMARD treatment in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation
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Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses
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Functional colour genes and signals of selection in colour‐polymorphic salamanders
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Decomposing metabolite set activity levels with PALS
10.1101/2020.06.07.138974
Schistosoma haematobium infection is associated with alterations in energy and purine-related metabolism in preschool-aged children
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Ranking Metabolite Sets by Their Activity Levels
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