Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro
Rashed, Khaled
Sahuc, Marie-Emmanuelle
Deloison, Gaspard
Calland, Noemie
Brodin, Priscille
Rouille, Yves
Seron, Karin
khaled Rashed
Rashed khaled
/ Khaled Rashed
/ Rashed, K.
ORCID: 0000-0003-0476-9098
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Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro
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Yves Rouillé
Rouillé Yves
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Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors
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The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence
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Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis
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Ethionamide Boosters: Synthesis, Biological Activity, and Structure-Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors
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High-content screening in infectious diseases
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Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ
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High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling
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High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery
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Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting
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Automated High-Throughput siRNA Transfection in Raw 264.7 Macrophages: A Case Study for Optimization Procedure
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Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
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High Content Screening Identifies Decaprenyl-Phosphoribose 2 ' Epimerase as a Target for Intracellular Antimycobacterial Inhibitors
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Systematic Genetic Nomenclature for Type VII Secretion Systems
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Control of M-tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP
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Aquatic insects and transmission of Mycobacterium ulcerans
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ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity
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Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis
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Protection against mycobacterium ulcerans lesion development by exposure to aquatic insect saliva
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Support vector machines for automatic detection of tuberculosis bacteria in confocal microscopy images
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Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues
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An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis
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Benzofuro 3,2-f 1 benzopyrans: A new class of antitubercular agents
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Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence
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High frequency of CD4(+) T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection
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Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence
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Evaluation of vaccines in the EU TB vaccine cluster using a guinea pig aerosol infection model of tuberculosis
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Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity
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Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics
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Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions
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Tuberculosis: from genome to vaccine
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Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RDI immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6
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Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens
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ESAT-6 proteins: protective antigens and virulence factors?
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Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex
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CD8(+)-T-cell responses of mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family
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Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
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A new evolutionary scenario for the Mycobacterium tuberculosis complex
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Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant
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Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides
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Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
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6-Oxocytidine containing oligonucleotides inhibit the HIV-1 integrase in vitro
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Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase
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Inhibition of the human immunodeficiency virus type 1 DNA integration by modified oligonucleotides
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Branched oligonucleotide-intercalator conjugate forming a parallel stranded structure inhibits HIV-1 integrase
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Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides
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Optimization of alternate-strand triple helix formation at the 5 '-TpA-3 ' and 5 '-ApT-3 ' junctions
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A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
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Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids
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ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton
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ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton
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Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles
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Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis
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Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays
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Host-pathogen systems for early drug discovery against tuberculosis
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Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages
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Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
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Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids
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Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry
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Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors
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Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis
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Proteomics of Mycobacterium infection: Moving towards a Better Understanding of Pathogen-Driven immunomodulation
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Synergy between circular bacteriocin AS-48 and ethambutol against Mycobacterium tuberculosis
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The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase
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Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis
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Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs
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Host-pathogen systems for early drug discovery against tuberculosis
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Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages
10.1016/j.chom.2017.07.020
Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
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Phenotypic assays for Mycobacterium tuberculosis infection
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A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening
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Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections
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Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation
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Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters
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Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis
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Mitochondrial Dynamics and Activity in Legionella-Infected Cells
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Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria
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Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication
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A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation
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Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls
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Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies.
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Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity.
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Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds.
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Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis.
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IRG1 controls immunometabolic host response and restricts intracellular Mycobacterium tuberculosis infection
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Worms' Antimicrobial Peptides.
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T(oo)bAd.
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Theaflavins, polyphenols of black tea, inhibit entry of hepatitis C virus in cell culture.
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Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro.
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Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.
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Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.
10.1021/jm300377g
Shortening the drug discovery pipeline: small molecule high content screening for lead discovery in neglected disease.
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Automated HTS/HCS for antivirals using visual HIV full replication assays.
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Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system.
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Cell microbiology interview
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Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts
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