Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism
Mohammad Tauqeer Alam Marnix H. Medema Eriko Takano Rainer Breitling
FEBS Letters, 2011-7
Eriko Takano
Takano Eriko
ORCID: 0000-0002-6791-3256
Synthetic biology advances for pharmaceutical production 10.1016/j.copbio.2015.02.004
Butyrolactone signalling circuits for synthetic biology 10.1016/j.cbpa.2015.06.024
Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block 10.1021/sb500368w
Judging synthetic biology risks 10.1126/science.aaa5253
Ribosylhopane, a novel bacterial hopanoid, as precursor of C35 bacteriohopanepolyols in Streptomyces coelicolor A3(2) 10.1002/cbic.201402261
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters 10.1016/j.cell.2014.06.034
Synthetic Biology of Natural Products 10.1002/9781118794623.ch19
Steps towards the synthetic biology of polyketide biosynthesis 10.1111/1574-6968.12365
A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis 10.1371/journal.pcbi.1004016
Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products 10.1371/journal.pcbi.1003822
Design-based re-engineering of biosynthetic gene clusters: Plug-and-play in practice 10.1016/j.copbio.2013.03.006
Modeling challenges in the synthetic biology of secondary metabolism 10.1021/sb4000228
Natural products: Tools and more special issue 10.1021/sb400063n
antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers. 10.1093/nar/gkt449
Detecting sequence homology at the gene cluster level with multigeneblast 10.1093/molbev/mst025
Synthetic microbiology. Metabolic pathways from the drawing board: New approaches of the biochemistry of natural products | Stoffwechselwege vom Reißbrett: neue Ansätze der Naturstoffbiochemie: Synthetische Mikrobiologie 10.1007/s12268-013-0267-3
MultiMetEval: Comparative and Multi-Objective Analysis of Genome-Scale Metabolic Models 10.1371/journal.pone.0051511
Characterisation of a natural variant of the -butyrolactone signalling receptor 10.1186/1756-0500-5-379
Metabolomics methods for the synthetic biology of secondary metabolism 10.1016/j.febslet.2012.02.008
Separating the wheat from the chaff: A prioritisation pipeline for the analysis of metabolomics datasets 10.1007/s11306-011-0341-0
A turning point for natural product discovery--ESF-EMBO research conference: synthetic biology of antibiotic production. 10.1111/j.1365-2958.2012.07984.x
Computational tools for the synthetic design of biochemical pathways 10.1038/nrmicro2717
Metabolomic analysis of a synthetic metabolic switch in Streptomyces coelicolor A3(2) 10.1002/pmic.201100254
Exploring the metabolic state of microorganisms using metabolomics 10.4155/bio.11.248
Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor 10.1186/1756-0500-4-325
Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism 10.1016/j.febslet.2011.06.014
Convergent transcription in the butyrolactone regulon in streptomyces coelicolor confers a bistable genetic switch for antibiotic biosynthesis 10.1371/journal.pone.0021974
AntiSMASH: Rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences 10.1093/nar/gkr466
Synthetic biology in streptomyces bacteria 10.1016/B978-0-12-385075-100021-4
Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus 10.1111/j.1751-7915.2010.00226.x
Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2) 10.1111/j.1751-7915.2010.00232.x
Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms 10.1038/nrmicro2478
The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways 10.1093/gbe/evq013
Genome-wide inference of regulatory networks in Streptomyces coelicolor 10.1186/1471-2164-11-578
Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2) 10.1099/mic.0.038281-0
Metabolomic characterization of the salt stress response in streptomyces coelicolor 10.1128/AEM.01992-09
Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor 10.1186/1471-2164-11-202
Genome-based phylogenetic analysis of Streptomyces and its relatives 10.1016/j.ympev.2009.11.019
Noncoding RNA of glutamine synthetase I modulates antibiotic production in Streptomyces coelicolor A3(2) 10.1128/JB.01374-09
The dynamic architecture of the metabolic switch in Streptomyces coelicolor 10.1186/1471-2164-11-10
Analysis of Two Additional Signaling Molecules in Streptomyces coelicolor and the Development of a Butyrolactone-Specific Reporter System 10.1016/j.chembiol.2009.08.010
Chapter 6 Regulation of Antibiotic Production by Bacterial Hormones 10.1016/S0076-6879(09)04806-X
A bistable gene switch for antibiotic biosynthesis: The butyrolactone regulon in Streptomyces coelicolor 10.1371/journal.pone.0002724
The border sequence of the balhimycin biosynthesis gene cluster from Amycolatopsis balhimycina contains bbr, encoding a StrR-like pathway-specific regulator 10.1159/000103599
ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesize γ-butyrolactones 10.1099/mic.0.2006/004432-0
A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2) 10.1007/s00203-006-0176-7
Identification of genes involved in siderophore transport in Streptomyces coelicolor A3(2) 10.1111/j.1574-6968.2006.00362.x
γ-Butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation 10.1016/j.mib.2006.04.003
A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor 10.1111/j.1365-2958.2005.04543.x
A rare leucine codon in adpA is implicated in the morphological defect of bldA mutants of Streptomyces coelicolor 10.1046/j.1365-2958.2003.03728.x
A complex role for the γ-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2) 10.1046/j.1365-2958.2001.02562.x
A single amino acid substitution in region 1.2 of the principal σ factor of Streptomyces coelicolor A3(2) results in pleiotropic loss of antibiotic production 10.1046/j.1365-2958.2000.02022.x
Purification and structural determination of SCB1, a γ-butyrolactone that elicits antibiotic production in Streptomyces coelicolor A3(2) 10.1074/jbc.275.15.11010
redD and actII-ORF4, pathway-specific regulatory genes for antibiotic production in Streptomyces coelicolor A3(2), are transcribed in vitro by an RNA polymerase holoenzyme containing ?hrdD 10.1128/jb.178.11.3402-3405.1996
Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp. 10.1016/0378-1119(95)00545-2
Stationary?phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated 10.1111/j.1365-2958.1993.tb01174.x
Transcriptional regulation of the redD transcriptional activator gene accounts for growth?phase?dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2) 10.1111/j.1365-2958.1992.tb01459.x
Purification and properties of a prokaryote type glutamine synthetase from the bialaphos producer Streptomyces hygroscopicus SF1293 10.1016/0922-338X(90)90032-R
The bialaphos resistance gene (bar) plays a role in both self-defense and bialaphos biosynthesis in streptomyces hygroscopicus 10.7164/antibiotics.41.1838
Replacement of streptomyces hygroscopicus genomic segments with in vitro altered DNA sequences 10.7164/antibiotics.41.226
The bialaphos biosynthetic genes of streptomyces hygroscopicus: Cloning and analysis of the genes involved in the alanylation step 10.7164/antibiotics.41.538
Bacterial microcompartments: biomaterials for synthetic biology-based compartmentalization strategies 10.1021/acsbiomaterials.5b00059
Natural Product Biosynthesis in Escherichia coli: Mentha Monoterpenoids 10.1016/bs.mie.2016.02.020
Bioinformatics for the synthetic biology of natural products: Integrating across the Design-Build-Test cycle 10.1039/c6np00018e
Synthetic biology of natural products 10.1101/cshperspect.a023994
SYNBIOCHEM - A SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals 10.1042/BST20160009
Towards synthesis of monoterpenes and derivatives using synthetic biology 10.1016/j.cbpa.2016.06.002
Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli 10.1021/acssynbio.5b00092
AntiSMASH 3.0-A comprehensive resource for the genome mining of biosynthetic gene clusters 10.1093/nar/gkv437
A ‘plug and play’ platform for the diverse monoterpene hydrocarbon scaffolds in Escherichia coli. 10.1002/slct.201600563
Selenzyme: Enzyme selection tool for pathway design 10.1101/188979
Orthogonal Regulatory Circuits for Escherichia coli Based on the γ-Butyrolactone System of Streptomyces coelicolor 10.1021/acssynbio.7b00425
A Toolbox for Diverse Oxyfunctionalisation of Monoterpenes 10.1038/s41598-018-32816-1
The “Three Cs” of Novel Antibiotic Discovery and Production through Synthetic Biology: Biosynthetic Gene Clusters, Heterologous Chassis, and Synthetic Microbial Consortia 10.1002/adbi.201800064
Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters 10.1038/s42003-019-0333-6
SelProm: A Queryable and Predictive Expression Vector Selection Tool for Escherichia coli 10.1021/acssynbio.8b00399
Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli 10.1371/journal.pbio.3000347
An automated pipeline for the screening of diverse monoterpene synthase libraries 10.1038/s41598-019-48452-2
Integrated Probabilistic Annotation: A Bayesian-Based Annotation Method for Metabolomic Profiles Integrating Biochemical Connections, Isotope Patterns, and Adduct Relationships 10.1021/acs.analchem.9b02354
Exploring novel bacterial terpene synthases 10.1371/journal.pone.0232220
Fine-tuning the regulation of Cas9 expression levels for efficient CRISPR-Cas9 mediated recombination in Streptomyces 10.1007/s10295-020-02277-5
Switchable foldamer ion channels with antibacterial activity 10.1039/D0SC02393K
Non-covalent protein-based adhesives for transparent substrates—bovine serum albumin vs. recombinant spider silk 10.1016/j.mtbio.2020.100068
Unravelling the γ-butyrolactone network in Streptomyces coelicolor by computational ensemble modelling 10.1371/journal.pcbi.1008039
Host Systems for the Production of Recombinant Spider Silk 10.1016/j.tibtech.2020.09.007
Investigation of the effects of actinorhodin biosynthetic gene cluster expression and a rpoB point mutation on the metabolome of Streptomyces coelicolor M1146 10.1016/j.jbiosc.2021.01.002
Blood, Sweat and Tears: Extraterrestrial Regolith Biocomposites with in Vivo Binders 10.26434/chemrxiv.14769369.v1
Blood, Sweat and Tears: Extraterrestrial Regolith Biocomposites with in Vivo Binders 10.26434/chemrxiv.14769369
Blood, sweat, and tears: extraterrestrial regolith biocomposites with in vivo binders 10.1016/j.mtbio.2021.100136
Marnix H. Medema
Medema Marnix H.
ORCID: 0000-0002-2191-2821
Bioinformatics Approaches and Software for Detection of Secondary Metabolic Gene Clusters 10.1007/978-1-62703-122-6_2
Synthetic Biology in Streptomyces Bacteria 10.1016/b978-0-12-385075-1.00021-4
Computational approaches to natural product discovery 10.1038/nchembio.1884
Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms 10.1038/nrmicro2478
A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis 10.1371/journal.pcbi.1004016
Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism 10.1016/j.febslet.2011.06.014
MultiMetEval: Comparative and Multi-Objective Analysis of Genome-Scale Metabolic Models 10.1371/journal.pone.0051511
The future of industrial antibiotic production: From random mutagenesis to synthetic biology 10.4161/bbug.2.4.16114
Metabolomics methods for the synthetic biology of secondary metabolism 10.1016/j.febslet.2012.02.008
Computational tools for the synthetic design of biochemical pathways 10.1038/nrmicro2717
A predicted physicochemically distinct sub-proteome associated with the intracellular organelle of the anammox bacterium Kuenenia stuttgartiensis 10.1186/1471-2164-11-299
Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus 10.1111/j.1751-7915.2010.00226.x
Denitrifying bacteria anaerobically oxidize methane in the absence of Archaea 10.1111/j.1462-2920.2008.01724.x
Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters 10.1016/j.cell.2014.06.034
Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products 10.1371/journal.pcbi.1003822
antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters 10.1093/nar/gkv437
Design-based re-engineering of biosynthetic gene clusters: plug-and-play in practice 10.1016/j.copbio.2013.03.006
Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block 10.1021/sb500368w
antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers 10.1093/nar/gkt449
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences 10.1093/nar/gkr466
The Sequence of a 1.8-Mb Bacterial Linear Plasmid Reveals a Rich Evolutionary Reservoir of Secondary Metabolic Pathways 10.1093/gbe/evq013
MS/MS networking guided analysis of molecule and gene cluster families 10.1073/pnas.1303471110
Detecting Sequence Homology at the Gene Cluster Level with MultiGeneBlast 10.1093/molbev/mst025
Complete Genome Sequence of the Frog Pathogen Mycobacterium ulcerans Ecovar Liflandii 10.1128/jb.02132-12
NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity 10.1093/nar/gkr323
Mechanisms and Evolution of Control Logic in Prokaryotic Transcriptional Regulation 10.1128/mmbr.00037-08
Genomic mutational analysis of the impact of the classical strain improvement program on β-lactam producing Penicillium chrysogenum. 10.1186/s12864-015-2154-4
Leucanicidin and endophenasides result from methyl-rhamnosylation by the same tailoring enzymes in Kitasatospora sp. MBT66 10.1021/acschembio.5b00801
Computational strategies for genome-based natural product discovery and engineering in fungi 10.1016/j.fgb.2016.01.006
The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters 10.1093/nar/gkw960
Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides 10.1038/nmicrobiol.2016.197
Editorial: Synthetic biology and bioinformatics 10.1039/c6np90031c
plantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters 10.1093/nar/gkx305
Genome-based exploration of the specialized metabolic capacities of the genus Rhodococcus 10.1186/s12864-017-3966-1
Mining prokaryotes for antimicrobial compounds: from diversity to function 10.1093/femsre/fux014
Recent development of antiSMASH and other computational approaches to mine secondary metabolite biosynthetic gene clusters 10.1093/bib/bbx146
Standardization for natural product synthetic biology 10.1039/c6np00030d
Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways 10.1039/c6np00035e
Draft Genome Sequence of a Porcine Commensal, Rothia nasimurium , Encoding a Nonribosomal Peptide Synthetase Predicted To Produce the Ionophore Antibiotic Valinomycin 10.1128/genomea.00453-17
SANDPUMA: ensemble predictions of nonribosomal peptide chemistry reveal biosynthetic diversity across Actinobacteria 10.1093/bioinformatics/btx400
Collaborating with Undergraduates To Contribute to Biochemistry Community Resources 10.1021/acs.biochem.7b00872
Road MAPs to engineer host microbiomes. 10.1016/j.mib.2017.11.023
Genome-wide analysis of bacterial determinants of plant growth promotion and induced systemic resistance by Pseudomonas fluorescens. 10.1111/1462-2920.13927
Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution. 10.1073/pnas.1705567114
antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification. 10.1093/nar/gkx319
Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products. 10.1016/j.fgb.2016.01.012
Exploration and exploitation of the environment for novel specialized metabolites. 10.1016/j.copbio.2018.01.017
Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology 10.1128/mSystems.00182-17
Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics. 10.1016/j.chembiol.2018.02.008
HEx: A heterologous expression platform for the discovery of fungal natural products. 10.1126/sciadv.aar5459
luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria. 10.1128/msystems.00208-17
A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology. 10.1021/jacs.7b13292
Evolution and Diversity of Biosynthetic Gene Clusters in Fusarium. 10.3389/fmicb.2018.01158
Involvement of Burkholderiaceae and sulfurous volatiles in disease-suppressive soils. 10.1038/s41396-018-0186-x
Genomic Identification and Analysis of Specialized Metabolite Biosynthetic Gene Clusters in Plants Using PlantiSMASH. 10.1007/978-1-4939-7874-8_15
A standardized workflow for submitting data to the Minimum Information about a Biosynthetic Gene cluster (MIBiG) repository: prospects for research-based educational experiences 10.1186/s40793-018-0318-y
The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters 10.1093/nar/gky1060
Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae 10.1101/463620
Mining bacterial genomes to reveal secret synergy 10.1074/jbc.H118.006669
Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters 10.1038/s42003-019-0333-6
Comprehensive mass spectrometry-guided plant specialized metabolite phenotyping reveals metabolic diversity in the cosmopolitan plant family Rhamnaceae 10.1111/tpj.14292
A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters 10.1186/s13104-019-4222-3
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline 10.1093/nar/gkz310
MolNetEnhancer: enhanced molecular networks by integrating metabolome mining and annotation tools 10.1101/654459
BiosyntheticSPAdes: Reconstructing Biosynthetic Gene Clusters From Assembly Graphs 10.1101/gr.243477.118
Genome Mining Approaches to Bacterial Natural Product Discovery 10.1016/b978-0-12-409547-2.14627-x
Computer-aided re-engineering of nonribosomal peptide and polyketide biosynthetic assembly lines 10.1039/C9NP00021F
PlantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters 10.1101/083535
MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools 10.3390/metabo9070144
Assessing Specialized Metabolite Diversity in the Cosmopolitan Plant Genus Euphorbia L. 10.3389/fpls.2019.00846
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome 10.1126/science.aaw9285
MIBiG 2.0: a repository for biosynthetic gene clusters of known function 10.1093/nar/gkz882
A metabolic pathway for bile acid dehydroxylation by the gut microbiome 10.1101/758557
Coevolution-based prediction of protein-protein interactions in polyketide biosynthetic assembly lines 10.1101/669291
The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery 10.1021/acscentsci.9b00806
Cultivation and functional characterization of 79 planctomycetes uncovers their unique biology 10.1038/s41564-019-0588-1
Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia 10.1101/856955
Drivers of metabolic diversification: how dynamic genomic neighbourhoods generate new biosynthetic pathways in the Brassicaceae 10.1111/nph.16338
Microbial and volatile profiling of soils suppressive to Fusarium culmorum of wheat 10.1098/rspb.2019.2527
Computational genomic discovery of diverse gene clusters harboring Fe-S flavoenzymes in anaerobic gut microbiota 10.1101/2020.03.06.976126
RRE-Finder: A Genome-Mining Tool for Class-Independent RiPP Discovery 10.1101/2020.03.14.992123
Linking genomics and metabolomics to chart specialized metabolic diversity 10.1039/D0CS00162G
Computational genomic discovery of diverse gene clusters harbouring Fe-S flavoenzymes in anaerobic gut microbiota 10.1099/mgen.0.000373
ARTS 2.0: feature updates and expansion of the Antibiotic Resistant Target Seeker for comparative genome mining 10.1093/nar/gkaa374
Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products 10.1101/2020.05.19.104752
Ecology and genomics of Actinobacteria: new concepts for natural product discovery 10.1038/s41579-020-0379-y
The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms 10.1038/s42003-020-0993-2
BiG-SLiCE: A Highly Scalable Tool Maps the Diversity of 1.2 Million Biosynthetic Gene Clusters 10.1101/2020.08.17.240838
Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia 10.1074/jbc.RA120.013528
Microbial natural product databases: moving forward in the multi-omics era 10.1039/D0NP00053A
Author Correction: The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms 10.1038/s42003-020-01228-1
RRE-Finder: a Genome-Mining Tool for Class-Independent RiPP Discovery 10.1128/mSystems.00267-20
Author Correction: The planctomycete Stieleria maiorica Mal15T employs stieleriacines to alter the species composition in marine biofilms 10.1038/s42003-020-01271-y
BiG-FAM: the biosynthetic gene cluster families database 10.1093/nar/gkaa812
Coevolution-based prediction of protein–protein interactions in polyketide biosynthetic assembly lines 10.1093/bioinformatics/btaa595
The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes 10.1093/nar/gkaa978
Pan-genome analysis and ancestral state reconstruction of class halobacteria: probability of a new super-order 10.1038/s41598-020-77723-6
BiG-MAP: an automated pipeline to profile metabolic gene cluster abundance and expression in microbiomes 10.1101/2020.12.14.422671
Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides 10.1371/journal.pbio.3001026
BiG-SLiCE: A highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters 10.1093/gigascience/giaa154
The year 2020 in natural product bioinformatics: an overview of the latest tools and databases 10.1039/D0NP00090F
Do size and shape matter? Exploring the interactions and the metabolome of the soil isolate Hylemonella gracilis 10.1101/2021.02.11.430889
A systematic analysis of metabolic pathways in the human gut microbiota 10.1101/2021.02.25.432841
Omics-based strategies to discover novel classes of RiPP natural products 10.1016/j.copbio.2020.12.008
Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria 10.1038/s41467-021-21163-x
The Surfactin-Like Lipopeptides From Bacillus spp.: Natural Biodiversity and Synthetic Biology for a Broader Application Range 10.3389/fbioe.2021.623701
Mining metagenomes for natural product biosynthetic gene clusters: unlocking new potential with ultrafast techniques 10.1101/2021.01.20.427441
Extracting the GEMs: Genotype, Environment, and Microbiome Interactions Shaping Host Phenotypes 10.3389/fmicb.2020.574053
A mammalian commensal of the oropharyngeal cavity produces antibiotic and antiviral valinomycin in vivo 10.21203/rs.3.rs-126949/v1
A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters 10.1016/j.chembiol.2020.11.009
cblaster: a remote search tool for rapid identification and visualisation of homologous gene clusters 10.1101/2020.11.08.370601
antiSMASH 6.0: improving cluster detection and comparison capabilities 10.1093/nar/gkab335
The gutSMASH web server: automated identification of primary metabolic gene clusters from the gut microbiota 10.1093/nar/gkab353
Mining genomes to illuminate the specialized chemistry of life 10.1038/s41576-021-00363-7
Dominant drivers of the human plasma metabolome 10.21203/rs.3.rs-688716/v1
A global survey of specialized metabolic diversity encoded in bacterial genomes 10.1101/2021.08.11.455920
cblaster: a remote search tool for rapid identification and visualization of homologous gene clusters 10.1093/bioadv/vbab016
Rainer Breitling
Breitling Rainer
ORCID: 0000-0001-7173-0922
Synthetic biology advances for pharmaceutical production 10.1016/j.copbio.2015.02.004
Judging synthetic biology risks 10.1126/science.aaa5253
Theridion zonulatum Thorell 1890, a senior synonym of Theridion zebrinusum Zhu 1998 10.2476/asjaa.63.79
Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose 10.1371/journal.ppat.1004689
TrypanoCyc: A community-led biochemical pathways database for Trypanosoma brucei 10.1093/nar/gku944
A fast algorithm for determining bounds and accurate approximate -values of the rank product statistic for replicate experiments 10.1186/s12859-014-0367-1
Metabolomic systems biology of protozoan parasites 10.1007/978-1-4614-1689-0_6
Synthetic Biology of Natural Products 10.1002/9781118794623.ch19
Stable isotope-labeling studies in metabolomics: New insights into structure and dynamics of metabolic networks 10.4155/bio.13.348
Steps towards the synthetic biology of polyketide biosynthesis 10.1111/1574-6968.12365
MetAssign: Probabilistic annotation of metabolites from LC-MS data using a Bayesian clustering approach 10.1093/bioinformatics/btu370
The Silicon Trypanosome. A Test Case of Iterative Model Extension in Systems Biology. 10.1016/B978-0-12-800143-1.00003-8
Phosphoenolpyruvate Carboxylase Identified as a Key Enzyme in Erythrocytic Plasmodium falciparum Carbon Metabolism 10.1371/journal.ppat.1003876
Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products 10.1371/journal.pcbi.1003822
Handling Uncertainty in Dynamic Models: The Pentose Phosphate Pathway in Trypanosoma brucei 10.1371/journal.pcbi.1003371
Design-based re-engineering of biosynthetic gene clusters: Plug-and-play in practice 10.1016/j.copbio.2013.03.006
Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure 10.1111/mmi.12374
Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis 10.1111/febs.12436
Modeling challenges in the synthetic biology of secondary metabolism 10.1021/sb4000228
Natural products: Tools and more special issue 10.1021/sb400063n
antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers. 10.1093/nar/gkt449
Detecting sequence homology at the gene cluster level with multigeneblast 10.1093/molbev/mst025
The exact probability distribution of the rank product statistics for replicated experiments 10.1016/j.febslet.2013.01.037
Mass appeal: Metabolite identification in mass spectrometry-focused untargeted metabolomics 10.1007/s11306-012-0434-4
Synthetic microbiology. Metabolic pathways from the drawing board: New approaches of the biochemistry of natural products | Stoffwechselwege vom Reißbrett: neue Ansätze der Naturstoffbiochemie: Synthetische Mikrobiologie 10.1007/s12268-013-0267-3
MzMatch-ISO: An R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data 10.1093/bioinformatics/bts674
LC-MS metabolomics from study design to data-analysis-using a versatile pathogen as a test case 10.5936/csbj.201301002
MultiMetEval: Comparative and Multi-Objective Analysis of Genome-Scale Metabolic Models 10.1371/journal.pone.0051511
Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection 10.1038/oncsis.2012.10
Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation 10.1021/ac3018795
Effect of iTRAQ labeling on the relative abundance of peptide fragment ions produced by MALDI-MS/MS 10.1021/pr300083x
Metabolomics methods for the synthetic biology of secondary metabolism 10.1016/j.febslet.2012.02.008
Separating the wheat from the chaff: A prioritisation pipeline for the analysis of metabolomics datasets 10.1007/s11306-011-0341-0
msCompare: A framework for quantitative analysis of label-free LC-MS data for comparative candidate biomarker studies 10.1074/mcp.M111.015974
Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents 10.1038/cddis.2012.35
IDEOM: An Excel interface for analysis of LC-MS-based metabolomics data 10.1093/bioinformatics/bts069
A turning point for natural product discovery--ESF-EMBO research conference: synthetic biology of antibiotic production. 10.1111/j.1365-2958.2012.07984.x
Computational tools for the synthetic design of biochemical pathways 10.1038/nrmicro2717
Dynamic modelling under uncertainty: The case of trypanosoma brucei energy metabolism 10.1371/journal.pcbi.1002352
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells 10.1038/cddis.2011.129
Metabolomic analysis of a synthetic metabolic switch in Streptomyces coelicolor A3(2) 10.1002/pmic.201100254
Toward global metabolomics analysis with hydrophilic interaction liquid chromatography-mass spectrometry: Improved metabolite identification by retention time prediction 10.1021/ac2021823
Exploring the metabolic state of microorganisms using metabolomics 10.4155/bio.11.248
Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor 10.1186/1756-0500-4-325
Bayesian Approaches for Mass Spectrometry-Based Metabolomics 10.1002/9781119970606.ch24
Comparative genome-scale metabolic modeling of actinomycetes: The topology of essential core metabolism 10.1016/j.febslet.2011.06.014
AntiSMASH: Rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences 10.1093/nar/gkr466
Physiological adaptation of the bacterium lactococcus lactis in response to the production of human CFTR 10.1074/mcp.M000052-MCP200
Supervisor's supporting comments 10.4155/bio.11.96
Synthetic biology in streptomyces bacteria 10.1016/B978-0-12-385075-100021-4
PeakML/mzMatch: A file format, Java library, R library, and tool-chain for mass spectrometry data analysis 10.1021/ac2000994
Erratum: Towards an unbiased metabolic profiling of protozoan parasites: Optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis (Analytical and Bioanalytical Chemistry DOI: 10.1007/s00216-010-4139-0) 10.1007/s00216-011-4796-7
Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus 10.1111/j.1751-7915.2010.00226.x
Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2) 10.1111/j.1751-7915.2010.00232.x
Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms 10.1038/nrmicro2478
What is systems biology? 10.3389/fphys.2010.00009
Apex peptide elution chain selection: A new strategy for selecting precursors in 2D-LC-MALDI-TOF/TOF experiments on complex biological samples 10.1021/pr1006944
Metabolomics to unveil and understand phenotypic diversity between pathogen populations 10.1371/journal.pntd.0000904
Towards an unbiased metabolic profiling of protozoan parasites: Optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis 10.1007/s00216-010-4139-0
The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways 10.1093/gbe/evq013
DiffCoEx: A simple and sensitive method to find differentially coexpressed gene modules 10.1186/1471-2105-11-497
Global genetic robustness of the alternative splicing machinery in Caenorhabditis elegans 10.1534/genetics.110.119677
The silicon trypanosome 10.1017/S0031182010000466
The potential of metabolomics for Leishmania research in the post-genomics era 10.1017/S0031182009992022
Metabolomic systems biology of trypanosomes 10.1017/S003118201000017X
A circuit model of the temporal pattern generator of Caenorhabditis egg-laying behavior 10.1186/1752-0509-4-81
Biomodel engineering - From structure to behavior 10.1007/978-3-642-11712-1_1
Metabolomic characterization of the salt stress response in streptomyces coelicolor 10.1128/AEM.01992-09
Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor 10.1186/1471-2164-11-202
Coronatine-insensitive 1 (COI1) mediates transcriptional responses of Arabidopsis thaliana to external potassium supply 10.1093/mp/ssq012
Genome-based phylogenetic analysis of Streptomyces and its relatives 10.1016/j.ympev.2009.11.019
Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines 10.1016/j.bcp.2009.08.013
The dynamic architecture of the metabolic switch in Streptomyces coelicolor 10.1186/1471-2164-11-10
Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms 10.1002/emmm.200900051
Expression quantitative trait loci are highly sensitive to cellular differentiation state 10.1371/journal.pgen.1000692
Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells 10.1186/1476-4598-8-80
DesignGG: An R-package and web tool for the optimal design of genetical genomics experiments 10.1186/1471-2105-10-188
An introduction to BioModel engineering, illustrated for signal transduction pathways 10.1007/978-3-540-95885-7_2
System-wide molecular evidence for phenotypic buffering in Arabidopsis 10.1038/ng.308
The yeast vacuolar membrane proteome 10.1074/mcp.M800372-MCP200
Probabilistic assignment of formulas to mass peaks in metabolomics experiments 10.1093/bioinformatics/btn642
Robust signaling networks of the adipose secretome 10.1016/j.tem.2008.08.006
Simple data-reduction method for high-resolution LC - MS data in metabolomics 10.4155/bio.09.146
Increasing the mass accuracy of high-resolution LC-MS data using background ions - A case study on the LTQ-Orbitrap 10.1002/pmic.200800314
Prosecutor: Parameter-free inference of gene function for prokaryotes using DNA microarray data, genomic context and multiple gene annotation sources 10.1186/1471-2164-9-495
Generalizing genetical genomics: getting added value from environmental perturbation 10.1016/j.tig.2008.08.001
Genetical genomics: Spotlight on QTL hotspots 10.1371/journal.pgen.1000232
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways 10.1093/bib/bbn026
C. elegans model identifies genetic modifiers of α-synuclein inclusion formation during aging 10.1371/journal.pgen.1000027
New surveyor tools for charting microbial metabolic maps 10.1038/nrmicro1797
A comparison of meta-analysis methods for detecting differentially expressed genes in microarray experiments 10.1093/bioinformatics/btm620
MetaNetter: Inference and visualization of high-resolution metabolomic networks 10.1093/bioinformatics/btm536
Greased hedgehogs: New links between hedgehog signaling and cholesterol metabolism 10.1002/bies.20663
Analyses of intricate kinetics of the serum proteome during and after colon surgery by protein expression time series 10.1002/pmic.200601047
Sequence polymorphisms cause many false cis eQTLs 10.1371/journal.pone.0000622
Microarray challenges in ecology 10.1016/j.tree.2007.01.013
FIVA: Functional Information Viewer and Analyzer extracting biological knowledge from transcriptome data of prokaryotes 10.1093/bioinformatics/btl658
A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, human and rat 10.1186/1471-2105-8-132
Predicting protein function by machine learning on amino acid sequences - A critical evaluation 10.1186/1471-2164-8-78
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans. 10.1371/journal.pgen.0020222
Precision mapping of the metabolome 10.1016/j.tibtech.2006.10.006
RankProd: A bioconductor package for detecting differentially expressed genes in meta-analysis 10.1093/bioinformatics/btl476
Ab initio prediction of metabolic networks using Fourier transform mass spectrometry data 10.1007/s11306-006-0029-z
Network theory to understand microarray studies of complex diseases 10.2174/156652406778195044
A lock-and-key model for protein-protein interactions 10.1093/bioinformatics/btl338
Biological microarray interpretation: The rules of engagement 10.1016/j.bbaexp.2006.06.003
Interspecies comparison of gene structure and computational analysis of gene regulation of 17beta-hydroxysteroid dehydrogenase type 1 10.1016/j.mce.2005.10.014
Regulation of ubiquitin-binding proteins by monoubiquitination 10.1038/ncb1354
Current challenges in quantitative modeling of epidermal growth factor signaling 10.1016/j.febslet.2005.10.034
Feature selection and the class imbalance problem in predicting protein function from sequence 10.2165/00822942-200594030-00004
Biological master games: Using biologists' reasoning to guide algorithm development for integrated functional genomics 10.1089/omi.2005.9.225
Rank-based methods as a non-parametric alternative of the t-statistic for the analysis of biological microarray data 10.1142/S0219720005001442
GeneRank: Using search engine technology for the analysis of microarray experiments 10.1186/1471-2105-6-233
FrankSum: New feature selection method for protein function prediction 10.1142/S0129065705000281
Vector analysis as a fast and easy method to compare gene expression responses between different experimental backgrounds 10.1186/1471-2105-6-181
The latent process decomposition of cDNA microarray data sets 10.1109/TCBB.2005.29
Inhibition of 17beta-hydroxysteroid dehydrogenases by phytoestrogens: Comparison with other steroid metabolizing enzymes 10.1016/j.jsbmb.2004.12.035
Biologically valid linear factor models of gene expressions 10.1093/bioinformatics/bth354
The potassium-dependent transcriptome of arabidopsis reveals a prominent role of jasmonic acid in nutrient signaling 10.1104/pp.104.046482
Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments 10.1016/j.febslet.2004.07.055
Graph-based iterative group analysis enhances microarray interpretation 10.1186/1471-2105-5-100
Iterative Group Analysis (iGA): A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments 10.1186/1471-2105-5-34
Pathogenesis of peroxisomal deficiency disorders (Zellweger syndrome) may be mediated by misregulation of the GABAergic system via the diazepam binding inhibitor 10.1186/1471-2431-4-5
Closing the gap: Identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis 10.1210/me.2002-0436
Isopentenyl-diphosphate isomerases in human and mouse: Evolutionary analysis of a mammalian gene duplication 10.1007/s00239-003-2476-8
Embryonic expression of cholesterogenic genes is restricted to distinct domains and colocalizes with apoptotic regions in mice 10.1016/S0169-328X(03)00094-9
A second gene for peroxisomal HMG-CoA reductase? A genomic reassessment 10.1194/jlr.R200010-JLR200
Loss of compartmentalization causes misregulation of lysine biosynthesis in peroxisome-deficient yeast cells 10.1128/EC.1.6.978-986.2002
Expression of muscarinic receptor types in the primate ovary and evidence for nonneuronal acetylcholine synthesis 10.1210/jc.86.1.349
Phytoestrogens inhibit human 17β-hydroxysteroid dehydrogenase type 5 10.1016/S0303-7207(00)00422-6
17β-hydroxysteroid dehydrogenase type 7 - An ancient 3-ketosteroid reductase of cholesterogenesis 10.1016/S0303-7207(00)00416-0
Evolution of 17β-HSD type 4, a multifunctional protein of β-oxidation 10.1016/S0303-7207(00)00415-9
Origin of the paired domain 10.1007/s004270000106
Determination of cDNA, gene structure and chromosomal localization of the novel human 17β-hydroxysteroid dehydrogenase type 7 10.1016/S0014-5793(99)01366-6
antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters. 10.1093/nar/gkv437
Incorporating peak grouping information for alignment of multiple liquid chromatography-mass spectrometry datasets. 10.1093/bioinformatics/btv072
A fast algorithm for determining bounds and accurate approximate p-values of the rank product statistic for replicate experiments. 10.1186/PREACCEPT-1857144210135244
Metabolomics for secondary metabolite research. 10.3390/metabo3041076
Computational modelling of kinase signalling cascades. 10.1007/978-1-60761-795-2_22
Feature selection and the class imbalance problem in predicting protein function from sequence. 10.2165/00822942-200504030-00004
Structure-based phylogenetic analysis of short-chain alcohol dehydrogenases and reclassification of the 17beta-hydroxysteroid dehydrogenase family. 10.1093/oxfordjournals.molbev.a003761
Synthetic Biology of Antibiotic Production 10.1002/3527600906.mcb.20120052
Transactions on Computational Systems Biology XII 10.1007/978-3-642-11712-1
Computation: A New Open Access Journal of Computational Chemistry, Computational Biology and Computational Engineering 10.3390/computation1020027
The future of industrial antibiotic production: From random mutagenesis to synthetic biology 10.4161/bbug.2.4.16114
Discriminating Microbial Species Using Protein Sequence Properties and Machine Learning 10.1007/978-3-540-77226-2_89
Analysis of Tiling Microarray Data by Learning Vector Quantization and Relevance Learning 10.1007/978-3-540-77226-2_88
Bacterial Microcompartments: Biomaterials for Synthetic Biology-Based Compartmentalization Strategies 10.1021/acsbiomaterials.5b00059
Mapping Determinants of Gene Expression Plasticity by Genetical Genomics in C. elegans 10.1371/journal.pgen.0020222.eor
Towards synthesis of monoterpenes and derivatives using synthetic biology 10.1016/j.cbpa.2016.06.002
Respectful Modeling: Addressing Uncertainty in Dynamic System Models for Molecular Biology 10.1016/j.tibtech.2016.12.008
Rational cell culture optimization enhances experimental reproducibility in cancer cells 10.1101/167148
Selenzyme: Enzyme selection tool for pathway design 10.1101/188979
Butyrolactone signalling circuits for synthetic biology 10.1016/j.cbpa.2015.06.024
Synthetic biology of natural products 10.1101/cshperspect.a023994
Advanced LC-MS applications for identification and quantification of the metabolome 10.2217/9781910419441.fseb2013.14.55
Re Genotyper: Detecting mislabeled samples in genetic data 10.1371/journal.pone.0171324
East meets west: On the true identity of cheiracanthium rupestre and xysticus albomaculatus (Arachnida: Araneae: Eutichuridae, Thomisidae) | Anmerkung zur wahren identität von cheiracanthium rupestre und xysticus albomaculatus (Arachnida: Araneae: Eutichuridae, Thomisidae) 10.5431/aramit5208
Phantom spiders 2: More notes on dubious spider species from Europe | Phantomspinnen 2: Weitere bemerkungen zu zweifelhaften spinnenarten aus Europa 10.5431/aramit5209
CodonGenie: Optimised ambiguous codon design tools 10.7717/peerj-cs.120
Public DNA barcoding data resolve the status of the genus Arboricaria (araneae: Gnaphosidae) | Öffentliche DNA-barcode-daten klären den Status der gattung arboricaria 10.5431/aramit5405
Bioinformatics for the synthetic biology of natural products: Integrating across the Design-Build-Test cycle 10.1039/c6np00018e
biochem4j: Integrated and extensible biochemical knowledge through graph databases 10.1371/journal.pone.0179130
SYNBIOCHEM - A SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals 10.1042/BST20160009
Phantom spiders: Notes on dubious spider species from Europe | Zusammenfassung. Phantomspinnen: Bemerkungen zu zweifelhaften spinnenarten aus Europa 10.5431/aramit5010
AntiSMASH 4.0 - improvements in chemistry prediction and gene cluster boundary identification 10.1093/nar/gkx319
LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes 10.1007/s11306-015-0827-2
A transatlantic perspective on 20 emerging issues in biological engineering 10.7554/eLife.30247
CodonGenie: optimised ambiguous codon design tools 10.7287/peerj.preprints.2797v1
CodonGenie: optimised ambiguous codon design tools 10.7287/peerj.preprints.2797
Rational cell culture optimization enhances experimental reproducibility in cancer cells 10.1038/s41598-018-21050-4
Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins 10.1128/mBio.02118-17
Orthogonal Regulatory Circuits for Escherichia coli Based on the γ-Butyrolactone System of Streptomyces coelicolor 10.1021/acssynbio.7b00425
Mobilising ion mobility mass spectrometry for metabolomics 10.1039/C8AN00902C
Defining informative priors for ensemble modeling in systems biology 10.1038/s41596-018-0056-z
The “Three Cs” of Novel Antibiotic Discovery and Production through Synthetic Biology: Biosynthetic Gene Clusters, Heterologous Chassis, and Synthetic Microbial Consortia 10.1002/adbi.201800064
Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters 10.1038/s42003-019-0333-6
SelProm: A Queryable and Predictive Expression Vector Selection Tool for Escherichia coli 10.1021/acssynbio.8b00399
Integrated Probabilistic Annotation: A Bayesian-Based Annotation Method for Metabolomic Profiles Integrating Biochemical Connections, Isotope Patterns, and Adduct Relationships 10.1021/acs.analchem.9b02354
Bioengineering horizon scan 2020 10.7554/eLife.54489
Unravelling the γ-butyrolactone network in Streptomyces coelicolor by computational ensemble modelling 10.1371/journal.pcbi.1008039
Host Systems for the Production of Recombinant Spider Silk 10.1016/j.tibtech.2020.09.007
Towards engineering and production of artificial spider silk using tools of synthetic biology 10.1049/enb.2019.0017
Investigation of the effects of actinorhodin biosynthetic gene cluster expression and a rpoB point mutation on the metabolome of Streptomyces coelicolor M1146 10.1016/j.jbiosc.2021.01.002
A completely resolved phylogenetic tree of British spiders 10.1101/2021.03.12.434792
Blood, Sweat and Tears: Extraterrestrial Regolith Biocomposites with in Vivo Binders 10.26434/chemrxiv.14769369.v1
Blood, Sweat and Tears: Extraterrestrial Regolith Biocomposites with in Vivo Binders 10.26434/chemrxiv.14769369
Blood, sweat, and tears: extraterrestrial regolith biocomposites with in vivo binders 10.1016/j.mtbio.2021.100136