Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors
Fadel Sayes
Catherine Blanc
Louis S. Ates
Nathalie Deboosere
Mickael Orgeur
Fabien Le Chevalier
Matthias I. Gröschel
Wafa Frigui
Ok-Ryul Song
Richard Lo-Man
Florence Brossier
Wladimir Sougakoff
Daria Bottai
Priscille Brodin
Pierre Charneau
Roland Brosch
Laleh Majlessi
Cell Reports, 2018
Wladimir SOUGAKOFF
SOUGAKOFF Wladimir
ORCID: 0000-0002-2447-517X
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Priscille Brodin
Brodin Priscille
ORCID: 0000-0003-0991-7344
Email: priscille.brodin@inserm.fr
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Evolution of Mycobacterium tuberculosis : New Insights into Pathogenicity and Drug Resistance
10.1128/microbiolspec.tbtb2-0020-2016
Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors
10.3389/fcimb.2020.00420
Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli
10.1038/s41564-021-00938-4
Wafa FRIGUI
FRIGUI Wafa
ORCID: 0000-0001-5172-7961
Mycobacterial virulence: impact on immunogenicity and vaccine research [version 1; peer review: 4 approved]
10.12688/f1000research.20572.1
Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection.
10.1016/j.celrep.2017.02.057
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis.
10.1371/journal.ppat.1006399
Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors.
10.1016/j.celrep.2018.03.125
pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence.
10.1038/nmicrobiol.2015.19
The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis.
10.1111/mmi.13266
Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis.
10.1038/srep16918
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection.
10.1371/journal.ppat.1005770
ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection.
10.1016/j.tube.2015.02.019
Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system.
10.1016/j.vaccine.2015.03.083
A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component.
10.1128/IAI.01824-14
Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis.
10.1038/ng.2517
Early trafficking events of Mycobacterium ulcerans within Naucoris cimicoides.
10.1111/j.1462-5822.2006.00790.x
Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation.
10.1111/j.1365-2958.2012.08001.x
ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis.
10.1093/infdis/jiq089
Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis.
10.1186/ar1949
Genome plasticity of BCG and impact on vaccine efficacy.
10.1073/pnas.0700869104
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.
10.1101/gr.5942807
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.
10.1073/pnas.0305877101
Common evolutionary origin for the unstable virulence plasmid pMUM found in geographically diverse strains of Mycobacterium ulcerans.
10.1128/JB.187.5.1668-1676.2005
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP.
10.1371/journal.ppat.0040033
RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection
10.1371/journal.ppat.1007139
Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis
10.1038/s41598-020-58967-8
Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro–American genetic background confers optimal vaccine potential
10.1016/j.ebiom.2020.102761