Mitochondrial Dynamics and Activity in Legionella-Infected Cells
Ok-Ryul Song Priscille Brodin Carmen Buchrieser Pedro Escoll
Carmen Buchrieser
Buchrieser Carmen
ORCID: 0000-0003-3477-9190
IroT/mavN, a new iron-regulated gene involved in Legionella pneumophila virulence against amoebae and macrophages 10.1111/1462-2920.12604
Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline 10.1038/ncomms5544
The Legionella pneumophila kai operon is implicated in stress response and confers fitness in competitive environments 10.1111/1462-2920.12223
Legionella pneumophila type IV effectors hijack the transcription and translation machinery of the host cell 10.1016/j.tcb.2014.06.002
Legionnaires' disease 10.1007/978-3-642-30144-5_94
Host epigenetic targeting by Legionella pneumophila | Reprogrammation épigénétique des cellules hôtes par Legionella pneumophila 10.1051/medsci/20132910010
Human single-chain urokinase is activated by the omptins PgtE of Salmonella enterica and Pla of Yersinia pestis despite mutations of active site residues 10.1111/mmi.12293
Genome dynamics in Legionella: The basis of versatility and adaptation to intracellular replication 10.1101/cshperspect.a009993
Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication 10.1016/j.chom.2013.03.004
The Legionella pneumophila orphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit 10.1111/j.1462-2920.2012.02889.x
CDNA library construction for next-generation sequencing to determine the transcriptional landscape of legionella pneumophila 10.1007/978-1-62703-161-5-34
Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes 10.1186/1471-2164-13-144
Post-translational modifications of host proteins by Legionella pneumophila: A sophisticated survival strategy 10.2217/fmb.12.9
Legionella pneumophila transcriptional response to chlorine treatment 10.1016/j.watres.2011.11.059
Population variation in NAIP functional copy number confers increased cell death upon Legionella pneumophila infection 10.1016/j.humimm.2011.10.014
Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions 10.3389/fmicb.2011.00208
Complete genome sequence of the animal pathogen Listeria ivanovii, which provides insights into host specificities and evolution of the genus Listeria 10.1128/JB.06120-11
Legionella: From protozoa to humans 10.3389/fmicb.2011.00182
Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes 10.1186/1471-2164-12-536
Fatty acid composition modulates sensitivity of Legionella pneumophila to warnericin RK, an antimicrobial peptide 10.1016/j.bbamem.2010.12.011
Specific real-time PCR for simultaneous detection and identification of Legionella pneumophila serogroup 1 in water and clinical samples 10.1128/AEM.02261-10
GamA is a eukaryotic-like glucoamylase responsible for glycogen- and starch-degrading activity of Legionella pneumophila 10.1016/j.ijmm.2010.08.016
Circadian clock proteins in prokaryotes: Hidden rhythms? 10.3389/fmicb.2010.00130
The origins of eukaryotic-like proteins in Legionella pneumophila 10.1016/j.ijmm.2010.04.016
Listeria rocourtiae sp. nov. 10.1099/ijs.0.017376-0
The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication 10.1111/j.1462-5822.2010.01467.x
Isotopologue profiling of Legionella pneumophila: Role of serine and glucose as carbon substrates 10.1074/jbc.M110.128678
The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila 10.1111/j.1462-2920.2010.02167.x
Two Important Bacterial Pathogens Causing Community Acquired Pneumonia: Streptococcus pneumoniae and Legionella pneumophila 10.1002/9783527629664.ch6
Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease 10.1371/journal.pgen.1000851
Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation 10.1111/j.1365-2958.2010.07094.x
Update on Legionnaires' disease: Pathogenesis, epidemiology, detection and control: MicroMeeting 10.1111/j.1365-2958.2010.07086.x
A trans-Acting Riboswitch Controls Expression of the Virulence Regulator PrfA in Listeria monocytogenes 10.1016/j.cell.2009.08.046
NeMeSys: A biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis 10.1186/gb-2009-10-10-r110
From functional genomics to systems (micro)biology 10.1016/j.mib.2009.09.001
Molecular mimicry: An important virulence strategy employed by Legionella pneumophila to subvert host functions 10.2217/fmb.09.47
Legionella pneumophila: Population genetics, phylogeny and genomics 10.1016/j.meegid.2009.05.004
Legionella pneumophila - Host interactions: Insights gained from comparative genomics and cell biology 10.1159/000235770
Genome sequence of Vibrio splendidus: An abundant planctonic marine species with a large genotypic diversity 10.1111/j.1462-2920.2009.01918.x
Listeria monocytogenes l-forms respond to cell wall deficiency by modifying gene expression and the mode of division 10.1111/j.1365-2958.2009.06774.x
Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila 10.1111/j.1365-2958.2009.06677.x
In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection 10.1371/journal.ppat.1000449
Significant role for ladC in initiation of Legionella pneumophila infection 10.1128/IAI.00209-08
Pathogenomics: An updated European Research Agenda 10.1016/j.meegid.2008.01.005
Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species 10.1101/gr.7229808
Transcriptional profiling of Legionella pneumophila biofilm cells and the influence of iron on biofilm formation 10.1099/mic.0.2007/008698-0
The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA 10.1111/j.1462-5822.2007.01005.x
Pathogenomics of Listeria spp. 10.1016/j.ijmm.2007.03.016
Legionella pathogenicity: Genome structure, regulatory networks and the host cell response 10.1016/j.ijmm.2007.03.009
Comparative transcriptome analysis of Listeria monocytogenes strains of the two major lineages reveals differences in virulence, cell wall, and stress response 10.1128/AEM.02730-06
Biodiversity of the species Listeria monocytogenes and the genus Listeria 10.1016/j.micinf.2007.05.002
Legionella pneumophila adaptation to intracellular life and the host response: Clues from genomics and transcriptomics 10.1016/j.febslet.2007.05.026
Genetic diversity of Listeria monocytogenes recovered from infected persons and pork, seafood and dairy products on retail sale in France during 2000 and 2001 10.1016/j.ijfoodmicro.2006.09.011
The presence of the internalin gene in natural atypically hemolytic Listeria innocua strains suggests descent from L. monocytogenes 10.1128/AEM.01796-06
Legionella pneumophila - A human pathogen that co-evolved with fresh water protozoa 10.1007/s00018-006-6391-1
Listeria genomics 10.1007/978-0-387-49376-3-3
Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86 10.1016/j.ijmm.2006.06.007
Use of DNA arrays for the analysis of outbreak-related strains of Listeria monocytogenes 10.1016/j.ijmm.2006.06.002
Growth-phase-dependent mobility of the lvh-encoding region in Legionella pneumophila strain Paris 10.1099/mic.0.29227-0
Involvement of closely related strains of a new clonal group of Listeria monocytogenes in the 1998-99 and 2002 multistate outbreaks of foodborne listeriosis in the United States 10.1089/fpd.2006.3.292
How to become a uropathogen: Comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains 10.1073/pnas.0603038103
Escherichia coli induces DNA double-strand breaks in eukaryotic cells 10.1126/science.1127059
Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila 10.1111/j.1462-5822.2006.00703.x
Genomic diversity and evolution within the species Streptococcus agalactiae 10.1016/j.micinf.2005.11.010
Adaptation of Legionella pneumophila to the host environment: Role of protein secretion, effectors and eukaryotic-like proteins 10.1016/j.mib.2005.12.009
How seryl-phosphorylated HPr inhibits PrfA, a transcription activator of Listeria monocytogenes virulence genes 10.1159/000089650
The genome of the social amoeba Dictyostelium discoideum 10.1038/nature03481
Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83:K24:H31) 10.1099/mic.0.27469-0
Growth inhibition of Listeria monocytogenes by a nonbacteriocinogenic Carnobacterium piscicola 10.1111/j.1365-2672.2004.02438.x
Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity 10.1038/ng1447
The pathogenicity island-associated K15 capsule determinant exhibits a novel genetic structure and correlates with virulence in uropathogenic Escherichia coli strain 536 10.1128/IAI.72.10.5993-6001.2004
DNA Macroarray for Identification and Typing of Staphylococcus aureus Isolates 10.1128/JCM.42.5.2054-2064.2004
Pathogenomics of mobile genetic elements of toxigenic bacteria 10.1078/1438-4221-00290
CAAT-Box, contigs-Assembly and Annotation Tool-Box for genome sequencing projects 10.1093/bioinformatics/btg490
New Aspects Regarding Evolution and Virulence of Listeria monocytogenes Revealed by Comparative Genomics and DNA Arrays 10.1128/IAI.72.2.1072-1083.2004
The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens 10.1038/nbt886
Transcriptome analysis of Listeria monocytogenes identifies three groups of genes differently regulated by PrfA 10.1046/j.1365-2958.2003.03413.x
Analysis of genome plasticity in pathogenic and commensal Escherichia coli isolates by use of DNA arrays 10.1128/JB.185.6.1831-1840.2003
Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease 10.1046/j.1365-2958.2002.03126.x
Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis 10.1046/j.1365-2958.2002.03080.x
A new evolutionary scenario for the Mycobacterium tuberculosis complex 10.1073/pnas.052548299
REALIS: Postgenomic analysis of Listeria monocytogenes 10.1002/cfg.137
Hpt, a bacterial homolog of the microsomal glucose-6-phosphate translocase, mediates rapid intracellular proliferation in Listeria 10.1073/pnas.012363899
Comparative genomics of Listeria species 10.1126/science.1063447
A plague o' both your hosts 10.1038/35097178
The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri 10.1046/j.1365-2958.2000.02179.x
Listeriolysin O as a reporter to identify constitutive and in vivo- inducible promoters in the pathogen Listeria monocytogenes 10.1128/IAI.68.6.3242-3250.2000
The high-pathogenicity island of Yersinia pseudotuberculosis can be inserted into any of the three chromosomal asn tRNA genes 10.1046/j.1365-2958.1998.01124.x
Characterization of Listeria strains isolated from soft cheese 10.1016/0168-1605(93)90220-B
Listeriosis outbreak in France in 1992. Microbial data | Epidémie de listériose en France en 1992 aspects microbiologiques 10.1016/S0399-077X(05)81214-4
Use of pulsed field gel electrophoresis to compare large DNA-restriction fragments of Listeria monocytogenes strains belonging to serogroups 1/2 and 3 10.1016/0168-1605(91)90121-5
The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signaling and gene expression of Legionella pneumophila. 10.1111/mmi.13265
Contractile actin cables induced by Bacillus anthracis lethal toxin depend on the histone acetylation machinery. 10.1002/cm.21256
Bacterial remodelling of the host epigenome: functional role and evolution of effectors methylating host histones. 10.1111/cmi.12463
Small RNAs, 5' UTR elements and RNA-binding proteins in intracellular bacteria: impact on metabolism and virulence. 10.1093/femsre/fuv022
From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts. 10.1007/82_2013_351
Induction of competence for natural transformation in Legionella pneumophila and exploitation for mutant construction. 10.1007/978-1-62703-161-5_9
Co-immunoprecipitation: protein-RNA and protein-DNA interaction. 10.1007/978-1-62703-161-5_36
Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence. 10.4161/rna.20270
[What do we learn from the genome of Legionella pneumophila?]. 10.1051/medsci/2005215455
Global analysis of gene expression in an rpoN mutant of Listeria monocytogenes. 10.1099/mic.0.26860-0
Comparative genomics uncovers large tandem chromosomal duplications in Mycobacterium bovis BCG Pasteur. 10.1002/1097-0061(20000630)17:2<111::AID-YEA17>3.0.CO;2-G
Monoclonality or oligoclonality of human herpesvirus 8 terminal repeat sequences in Kaposi's sarcoma and other diseases. 10.1093/jnci/92.9.729
Environmental treasures: co-isolation of the first marine Chlamydiae and its protozoan host. 10.1111/1462-2920.13264
Modulation of Host Autophagy during Bacterial Infection: Sabotaging Host Munitions for Pathogen Nutrition. 10.3389/fimmu.2016.00081
Legionella pneumophila Pathogenesis: Lessons Learned from Genomics 10.1007/978-0-387-70896-6_1
Evolution of Listeria monocytogenes 10.1128/9781555815639.ch41
Genomics of the Opportunistic Pathogen Legionella pneumophila 10.1002/352760801x.ch15
Genome Sequencing and Genomics 10.1128/9781555815660.ch89
Génomique comparative 10.1016/s0924-4204(02)85003-x
Listeria monocytogenes and the Genus Listeria 10.1007/0-387-30744-3_11
What Genomics Has Taught Us about Intracellular Pathogens: the Example of Listeria monocytogenes 10.1128/9781555815530.ch14
Genomics of Listeria monocytogenes and Other Members of the Genus Listeria 10.1128/9781555816902.ch10
Genetic Tools for Use with Listeria monocytogenes 10.1128/9781555816513.ch51
Gene Expression and Virulence in Legionella: the Flagellar Regulon 10.1128/9781555815660.ch79
Legionella pneumophilarestrains autophagy by modulating the host's sphingolipid metabolism 10.1080/15548627.2016.1166325
An improved direct viable count for the enumeration of bacteria in milk 10.1016/0168-1605(93)90167-f
Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua : clues for evolution and pathogenicity 10.1016/s0928-8244(02)00448-0
Interdomain Horizontal Gene Transfer Shaped the Genomes of Legionella pneumophila and Legionella longbeachae 10.1007/978-1-4614-7780-8_11
The Genus Listeria and Listeria monocytogenes 10.1201/9781420015188.ch1
Characterization of an acetyltransferase that detoxifies aromatic chemicals in Legionella pneumophila 10.1042/bj20120528
Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy 10.1073/pnas.1522067113
Genome Plasticity in Legionella pneumophila and Legionella longbeachae: Impact on Host Cell Exploitation 10.1128/9781555817213.ch5
Genetic Diversity of Legionella pneumophila 10.1128/9781555815660.ch86
Subtyping of Listeria monocytogenes serovar 4b by use of low-frequency-cleavage restriction endonucleases and pulsed-field gel electrophoresis 10.1016/0923-2508(91)90080-t
The Legionella pneumophila LetA/LetS Two-Component System Exhibits Rheostat-Like Behavior 10.1128/iai.01107-09
Crystal structure of Legionella pneumophila Lpp1115 / KaiB 10.2210/pdb4kun/pdb
Control of Flagellar Gene Regulation in Legionella pneumophila and Its Relation to Growth Phase 10.1128/jb.00610-09
The Legionella Autoinducer Synthase LqsA Produces an  -Hydroxyketone Signaling Molecule 10.1074/jbc.m801929200
Nicotinic Acid Modulates Legionella pneumophila Gene Expression and Induces Virulence Traits 10.1128/iai.00999-12
Characterization of a Variant of vga(A) Conferring Resistance to Streptogramin A and Related Compounds 10.1128/aac.44.9.2271-2275.2000
Bringing the Genome of Legionella pneumophila to Life: the Transcriptional Program during Infection of Acanthamoeba castellanii 10.1128/9781555815660.ch84
Differentiation of the Major Listeria monocytogenes Serovars by Multiplex PCR 10.1128/jcm.42.8.3819-3822.2004
Synergistic Contribution of the Legionella pneumophila lqs Genes to Pathogen-Host Interactions 10.1128/jb.01002-08
Molecular epidemiology, phylogeny and evolution of Legionella. 10.1016/j.meegid.2016.04.033
Rapid detection and evolutionary analysis of Legionella pneumophila serogroup 1 sequence type 47. 10.1016/j.cmi.2016.11.019
The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system 10.1371/journal.pgen.1006629
Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila 10.1371/journal.pgen.1006855
Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages 10.1016/j.chom.2017.07.020
Manipulation of Autophagy by Bacterial Pathogens Impacts Host Immunity 10.21775/cimb.025.081
A Unique cis -Encoded Small Noncoding RNA Is Regulating Legionella pneumophila Hfq Expression in a Life Cycle-Dependent Manner 10.1128/mbio.02182-16
MAMs are attractive targets for bacterial repurposing of the host cell 10.1002/bies.201600171
Legionella longbeachae is immunologically silent and highly virulent in vivo 10.1093/infdis/jiw560
Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently 10.1101/gr.209536.116
Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires’ disease 10.1186/s13059-014-0505-0
Manipulation of Autophagy by Bacterial Pathogens Impacts Host Immunity 10.21775/9781910190692.04
Legionella pneumophila CsrA regulates a metabolic switch from amino acid to glycerolipid metabolism 10.1098/rsob.170149
Intracellular parasitism, the driving force of evolution of Legionella pneumophila and the genus Legionella 10.1038/s41435-019-0074-z
Editorial: Pathogens and disease special issue ETOX18 10.1093/femspd/fty091
Legionella Effectors Explored with INSeq: New Functional Insights 10.1016/j.tim.2018.01.003
A Ca2+-regulated deAMPylation switch in human and bacterial FIC proteins 10.1101/323253
A Comprehensive Review on the Manipulation of the Sphingolipid Pathway by Pathogenic Bacteria 10.3389/fcell.2019.00168
A Ca2+-regulated deAMPylation switch in human and bacterial FIC proteins 10.1038/s41467-019-09023-1
Legionella pneumophila infection and antibiotic treatment engenders a highly disturbed pulmonary microbiome with decreased microbial diversity 10.1101/808238
Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg‐like metabolism? 10.1111/febs.14446
Editorial overview: Host–pathogen interactions shaped through evolutionary and regulatory processes 10.1016/j.mib.2018.02.001
Sorting of Phagocytic Cells Infected with Legionella pneumophila 10.1007/978-1-4939-9048-1_11
Analysis of the Pulmonary Microbiome Composition of Legionella pneumophila-Infected Patients 10.1007/978-1-4939-9048-1_27
Mitochondrial Dynamics and Activity in Legionella-Infected Cells 10.1007/978-1-4939-9048-1_13
Symbiont-Mediated Defense against Legionella pneumophila in Amoebae 10.1128/mbio.00333-19
Intracellular parasitism, the driving force of evolution of Legionella pneumophila and the genus Legionella 10.1016/j.micinf.2019.06.012
Evolutionary Dissection of the Dot/Icm System Based on Comparative Genomics of 58 Legionella Species 10.1093/gbe/evz186
Metabolic reprogramming: an innate cellular defence mechanism against intracellular bacteria? 10.1016/j.coi.2019.05.009
The Life Cycle of L. pneumophila: Cellular Differentiation Is Linked to Virulence and Metabolism 10.3389/fcimb.2018.00003
Biological Diversity and Evolution of Type IV Secretion Systems 10.1007/978-3-319-75241-9_1
The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection 10.1016/j.jmb.2018.04.032
Legionnaires’ Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella 10.1146/annurev-pathmechdis-012419-032742
The pleiotropic Legionella transcription factor LvbR links the Lqs and c‐di‐GMP regulatory networks to control biofilm architecture and virulence 10.1111/1462-2920.14523
Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL 10.1111/cmi.12852
More than 18,000 effectors in theLegionellagenus genome provide multiple, independent combinations for replication in human cells 10.1073/pnas.1808016116
Celebrating the career and legacy of Professor Pascale Cossart 10.1111/mmi.14478
Persistent Legionnaires’ Disease and Associated Antibiotic Treatment Engender a Highly Disturbed Pulmonary Microbiome Enriched in Opportunistic Microorganisms 10.1128/mBio.00889-20
Danger-associated metabolic modifications during bacterial infection of macrophages 10.1093/intimm/dxaa035
Evolution and function of bacterial RCC1 repeat effectors 10.1111/cmi.13246
Molecular Mimicry: a Paradigm of Host-Microbe Coevolution Illustrated by Legionella 10.1128/mBio.01201-20
The unique Brucella effectors NyxA and NyxB target SENP3 to modulate the subcellular localisation of nucleolar proteins 10.1101/2021.04.23.441069
Reverting the mode of action of the mitochondrial FOF1-ATPase by Legionella pneumophila preserves its replication niche 10.1101/2021.05.12.443790
Priscille Brodin
Brodin Priscille
ORCID: 0000-0003-0991-7344
How can nanoparticles contribute to antituberculosis therapy? 10.1016/j.drudis.2017.01.011
Host-directed therapies offer novel opportunities for the fight against tuberculosis 10.1016/j.drudis.2017.05.005
A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone 10.3390/toxins9070227
A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone 10.3390/toxins9070227 10.3390/toxins9070227.
Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections 10.2217/nnm-2016-0364
Cyclodextrin-based nanocarriers containing a synergic drug combination: a potential formulation for pulmonary administration of antitubercular drugs 10.1016/j.ijpharm.2017.05.030 10.1016/j.ijpharm.2017.05.030.
Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism 10.1007/s00401-016-1652-z
Host-directed therapies offer novel opportunities for the fight against tuberculosis 10.1016/j.drudis.2017.05.005 10.1016/j.drudis.2017.05.005.
Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria 10.1111/mmi.13535
Impact of pe_ pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis 10.3389/fcimb.2017.00137
LppM impact on the colonization of macrophages by Mycobacterium tuberculosis 10.1111/cmi.12619
Phenotypic assays for Mycobacterium tuberculosis infection 10.1002/cyto.a.23129 10.1002/cyto.a.23129.
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420 10.1126/science.aag1006
A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters 10.1039/c5ob02630j
Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro 10.1007/s00705-016-2771-5
Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization 10.1016/j.str.2016.07.009
Mycolactone The amazing analgesic mycobacterial toxin 10.1051/medsci/20163202007
STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection 10.1038/srep29297
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 10.1021/cb5007163
Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo 10.1371/journal.ppat.1004650
High content screening in chemical biology: overview and main challenges 10.1051/medsci/20153102016
High-Content Screening Technology Combined with a Human Granuloma Model as a New Approach To Evaluate the Activities of Drugs against Mycobacterium tuberculosis 10.1128/aac.03705-14
Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system 10.1016/j.vaccine.2015.03.083
Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro 10.3389/fmicb.2015.00438
Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action 10.1128/jvi.01473-15
Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays 10.1007/978-1-4939-2450-9_24
A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening 10.3791/51114
Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches 10.1021/jm500422b
Mycobacterial Toxin Induces Analgesia in Buruli Ulcer by Targeting the Angiotensin Pathways 10.1016/j.cell.2014.04.040
Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro 10.1016/j.jff.2014.09.022
A novel specific edge effect correction method for RNA interference screenings 10.1093/bioinformatics/btr648
Discovery of Novel N-Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis 10.1021/jm3003779
Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors 10.1021/jm200825u
The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence 10.1371/journal.pone.0047573
Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis 10.1371/journal.pone.0026675
Ethionamide Boosters: Synthesis, Biological Activity, and Structure-Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors 10.1021/jm200076a
High-content screening in infectious diseases 10.1016/j.cbpa.2011.05.023
Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ 10.1099/mic.0.038133-0
High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling 10.1371/journal.ppat.1001100
High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery 10.4155/fmc.10.223
Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting 10.1016/j.biomaterials.2009.09.044
Automated High-Throughput siRNA Transfection in Raw 264.7 Macrophages: A Case Study for Optimization Procedure 10.1177/1087057108328762
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis 10.1126/science.1171583
High Content Screening Identifies Decaprenyl-Phosphoribose 2 ' Epimerase as a Target for Intracellular Antimycobacterial Inhibitors 10.1371/journal.ppat.1000645
Systematic Genetic Nomenclature for Type VII Secretion Systems 10.1371/journal.ppat.1000507
Control of M-tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP 10.1371/journal.ppat.0040033
Aquatic insects and transmission of Mycobacterium ulcerans 10.1051/medsci/20072367572
ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity 10.1128/jb.00469-07
Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis 10.1371/journal.ppat.0030062
Protection against mycobacterium ulcerans lesion development by exposure to aquatic insect saliva 10.1371/journal.pmed.0040064
Support vector machines for automatic detection of tuberculosis bacteria in confocal microscopy images 10.1109/isbi.2007.356794
Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues 10.1016/j.bmc.2006.12.009
An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis 10.1128/iai.74.4.2128-2137.2006
Benzofuro 3,2-f 1 benzopyrans: A new class of antitubercular agents 10.1016/j.bmc.2006.03.033
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence 10.1128/iai.74.1.88-98.2006
High frequency of CD4(+) T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection 10.1128/iai.02086-05
Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence 10.1128/jb.00631-06
Evaluation of vaccines in the EU TB vaccine cluster using a guinea pig aerosol infection model of tuberculosis 10.1016/
Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity 10.1074/jbc.M503515200
Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics 10.1099/mic.0.27799-0
Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions 10.1016/j.jmb.2005.05.049
Tuberculosis: from genome to vaccine 10.1586/14760584.4.4.541
Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RDI immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6 10.1128/iai.72.4.2170-2176.2004
Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens 10.1086/421468
ESAT-6 proteins: protective antigens and virulence factors? 10.1016/j.tim.2004.09.007
Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex 10.1099/mic.0.26662-0
CD8(+)-T-cell responses of mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family 10.1128/iai.71.12.7173-7177.2003
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis 10.1038/nm859
A new evolutionary scenario for the Mycobacterium tuberculosis complex 10.1073/pnas.052548299
Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant 10.1128/iai.70.10.5568-5578.2002
Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides 10.1021/bi015732y
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti 10.1046/j.1365-2958.2002.03237.x
6-Oxocytidine containing oligonucleotides inhibit the HIV-1 integrase in vitro 10.1081/ncn-100002322
Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase 10.1021/bi000398b
Inhibition of the human immunodeficiency virus type 1 DNA integration by modified oligonucleotides 10.1023/a:1026631910681
Branched oligonucleotide-intercalator conjugate forming a parallel stranded structure inhibits HIV-1 integrase 10.1016/s0014-5793(99)01350-2
Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides 10.1080/07328319908044831
Optimization of alternate-strand triple helix formation at the 5 '-TpA-3 ' and 5 '-ApT-3 ' junctions 10.1093/nar/27.15.3029
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus 10.1074/jbc.272.25.16010
Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids 10.1073/pnas.1707840114
ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton 10.15252/embr.201744371
ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton 10.15252/embr.201744371 10.15252/embr.201744371.
Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles 10.1038/s41598-017-05453-3
Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis 10.1038/s41598-017-11843-4 10.1038/s41598-017-11843-4.
Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays 10.1021/acschembio.7b00091
Host-pathogen systems for early drug discovery against tuberculosis 10.1016/j.mib.2017.11.017 10.1016/j.mib.2017.11.017.
Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages 10.1016/j.chom.2017.07.020 10.1016/j.chom.2017.07.020. Epub 2017 Aug 31.
Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling 10.1016/j.celrep.2017.08.101 10.1016/j.celrep.2017.08.101.
Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids 10.1073/pnas.1707840114 10.1073/pnas.1707840114.
Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry 10.1128/jvi.01982-17
Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors 10.1016/j.celrep.2018.03.125
Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis 10.1016/j.bioorg.2018.08.025
Proteomics of Mycobacterium infection: Moving towards a Better Understanding of Pathogen-Driven immunomodulation 10.3389/fimmu.2018.00086
Synergy between circular bacteriocin AS-48 and ethambutol against Mycobacterium tuberculosis 10.1128/aac.00359-18
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase 10.1016/
Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis 10.1038/s41598-017-11843-4
Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs 10.1016/j.ijpharm.2017.05.030
Host-pathogen systems for early drug discovery against tuberculosis 10.1016/j.mib.2017.11.017
Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages 10.1016/j.chom.2017.07.020
Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling 10.1016/j.celrep.2017.08.101
Phenotypic assays for Mycobacterium tuberculosis infection 10.1002/cyto.a.23129
A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening 10.1002/cyto.a.20627
Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections 10.1002/ppsc.201800360
Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation 10.1074/mcp.RA119.001316
Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters 10.3389/fphar.2019.00378
Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis 10.1021/acsnano.8b07902
Mitochondrial Dynamics and Activity in Legionella-Infected Cells 10.1007/978-1-4939-9048-1_13
Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria 10.3389/fmicb.2018.02258
Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication 10.1128/jvi.02009-18
A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation 10.1039/C9OB00680J
Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls 10.3390/toxins11090516
Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies. 10.3389/fimmu.2020.569127
Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity. 10.1021/acsinfecdis.9b00277
Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds. 10.1371/journal.pone.0227224
Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis. 10.1016/j.vaccine.2019.11.085
IRG1 controls immunometabolic host response and restricts intracellular Mycobacterium tuberculosis infection 10.1101/761551
Worms' Antimicrobial Peptides. 10.3390/md17090512
Theaflavins, polyphenols of black tea, inhibit entry of hepatitis C virus in cell culture. 10.1371/journal.pone.0198226
Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro. 10.3389/fmicb.2015.00488
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. 10.1038/nm.3262
Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. 10.1021/jm300377g
Shortening the drug discovery pipeline: small molecule high content screening for lead discovery in neglected disease. 10.1186/1753-6561-5-s1-p38
Automated HTS/HCS for antivirals using visual HIV full replication assays. 10.1186/1742-4690-6-s2-p82
Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system. 10.4049/jimmunol.174.6.3570
Cell microbiology interview 10.1111/cmi.13288
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts 10.1099/mgen.0.000505