Dual CCR2/5 Antagonist Attenuates Obesity-Induced Insulin Resistance by Regulating Macrophage Recruitment and M1/M2 Status
Ji Hye Huh
Hong Min Kim
Eun Soo Lee
Mi Hye Kwon
Bo Ra Lee
Hyun-Jeong Ko
Choon Hee Chung
Obesity (Silver Spring, Md.), 2017-12-27
Ji Hye Huh
Huh Ji Hye
ORCID: 0000-0001-5445-8007
Relationship between Regional Body Fat Distribution and Diabetes Mellitus: 2008 to 2010 Korean National Health and Nutrition Examination Surveys
10.4093/dmj.2017.41.1.51
Dual CCR2/5 Antagonist Attenuates Obesity-Induced Insulin Resistance by Regulating Macrophage Recruitment and M1/M2 Status
10.1002/oby.22103
Metabolic syndrome status over 2 years predicts incident chronic kidney disease in mid-life adults: a 10-year prospective cohort study
10.1038/s41598-018-29958-7
Metabolic syndrome epidemic among Korean adults: Korean survey of Cardiometabolic Syndrome (2018)
10.1016/j.atherosclerosis.2018.08.003
Contribution of obesity as an effect regulator to an association between serum leptin and incident metabolic syndrome
10.1016/j.cca.2018.09.038
Metabolic Syndrome Severity Score in Korean Adults: Analysis of the 2010–2015 Korea National Health and Nutrition Examination Survey
10.3346/jkms.2019.34.e48
Prospective Study of Sex-Specific Adiponectin Changes and Incident Metabolic Syndrome: The ARIRANG Study
10.3390/jcm8050599
Association between Serum Urate and Risk of Hypertension in Menopausal Women with XDH Gene
10.3390/jcm8050738
Natural course of fatty liver in 36,195 South Korean adults
10.1038/s41598-019-44738-7
Impact of Longitudinal Changes in Metabolic Syndrome Status over 2 Years on 10-Year Incident Diabetes Mellitus
10.4093/dmj.2018.0111
HOMA-estimated insulin resistance as an independent prognostic factor in patients with acute pancreatitis
10.1038/s41598-019-51466-5
Fatty liver index and development of cardiovascular disease in Koreans without pre-existing cardiovascular disease: a large population-based study
10.21203/rs.2.22994/v1
Fatty liver index and development of cardiovascular disease in Koreans without pre-existing myocardial infarction and ischemic stroke: a large population-based study
10.21203/rs.2.22994/v2
The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study
10.1186/s12933-020-01021-8
Fatty liver index and development of cardiovascular disease in Koreans without pre-existing myocardial infarction and ischemic stroke: a large population-based study
10.1186/s12933-020-01025-4
Metabolic Syndrome Severity Score for Predicting Cardiovascular Events: A Nationwide Population-Based Study from Korea
10.4093/dmj.2020.0103
Metabolic Syndrome Fact Sheet 2021: Executive Report
10.51789/cmsj.2021.1.e15
Choon Chung
Chung Choon
ORCID: 0000-0003-1144-7206
Prospective study of serum uric acid levels and incident metabolic syndrome in a Korean rural cohort
10.1016/j.atherosclerosis.2015.04.797
Comparison of insulin intensification strategies with insulin lispro low mixture twice daily versus basal insulin glargine and prandial insulin lispro once daily in East Asian and Caucasian patients with type 2 diabetes mellitus
10.1111/1753-0407.12426
Effect of pinitol on glucose metabolism and adipocytokines in uncontrolled type 2 diabetes
10.1016/j.diabres.2007.01.066
Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia)
10.1111/j.1463-1326.2012.01618.x
Serum sex hormone-binding globulin levels are independently associated with nonalcoholic fatty liver disease in people with type 2 diabetes
10.1016/j.diabres.2011.07.029
Gender-specific association between urinary sodium excretion and body composition: Analysis of the 2008-2010 Korean National Health and Nutrition Examination Surveys
10.1016/j.metabol.2015.03.010
Mulberry leaf extract increases adiponectin in murine 3T3-L1 adipocytes
10.1016/j.nutres.2011.12.003
Optimal hemoglobin A1C Cutoff Value for Diagnosing type 2 diabetes mellitus in Korean adults
10.1016/j.diabres.2012.09.030
Peroxisome proliferator-activated receptor-δ activation ameliorates albuminuria by preventing nephrin loss and restoring podocyte integrity in Type 2 diabetes
10.1093/ndt/gfs358
Non-diabetic Renal Disease in Patients with Non-insulin Dependent Diabetes Mellitus
10.3349/ymj.1999.40.4.321
Effects of pentoxifylline on proteinuria and glucose control in patients with type 2 diabetes: A prospective randomized double-blind multicenter study
10.1186/s13098-015-0060-1
Relationship between regional body fat distribution and diabetes mellitus: 2008 to 2010 Korean national health and nutrition examination surveys
10.4093/dmj.2017.41.1.51
Combined use of basal insulin analog and acarbose reduces postprandial glucose in patients with uncontrolled type 2 diabetes
10.1111/jdi.12261
Change in quality of life in patients with acromegaly after treatment with octreotide LAR: First application of AcroQoL in Korea
10.1136/bmjopen-2014-006898
Relationships between adiponectin and the status of glucose metabolism in Koreans
10.1007/BF03216466
A randomized, double-blind, placebo-controlled, phase II clinical trial to investigate the efficacy and safety of oral DA-1229 in patients with type 2 diabetes mellitus who have inadequate glycaemic control with diet and exercise
10.1002/dmrr.2613
Basal-prandial versus premixed insulin in patients with type 2 diabetes requiring insulin intensification after basal insulin optimization: A 24-week randomized non-inferiority trial
10.1111/1753-0407.12312
A 52-week extension study of switching from gemigliptin vs sitagliptin to gemigliptin only as add-on therapy for patients with type 2 diabetes who are inadequately controlled with metformin alone
10.1111/dom.13256
α-Mangostin ameliorates hepatic steatosis and insulin resistance by inhibition C-C chemokine receptor 2
10.1371/journal.pone.0179204
Upregulation of mitochondrial Nox4 mediates TGF-β-induced apoptosis in cultured mouse podocytes
10.1152/ajprenal.00438.2013
The association between pentraxin 3 and insulin resistance in obese children at baseline and after physical activity intervention
10.1016/j.cca.2012.06.002
IGF-I of serum and vitreous fluid in patients with diabetic proliferative retinopathy
10.1016/0168-8227(94)90024-8
Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats
10.3349/ymj.2007.48.5.847
Effects of lobeglitazone, a novel thiazolidinedione, on bone mineral density in patients with type 2 diabetes mellitus over 52 weeks
10.4093/dmj.2017.41.5.377
Limited effect of CpG ODN in preventing type 1 diabetes in NOD mice
10.3349/ymj.2005.46.3.341
Association between alcohol intake amount and prevalence of metabolic syndrome in Korean rural male population
10.1016/j.diabres.2010.01.009
Comparison of acarbose and voglibose in diabetes patients who are inadequately controlled with basal insulin treatment: Randomized, parallel, open-label, active-controlled study
10.3346/jkms.2014.29.1.90
Efficacy of glimepiride/metformin fixed-dose combination vs metformin uptitration in type 2 diabetic patients inadequately controlled on low-dose metformin monotherapy: A randomized, open label, parallel group, multicenter study in Korea
10.1111/jdi.12201
Effect of a short-term physical activity intervention on liver fat content in obese children
10.1139/apnm-2017-0406
Effects of spironolactone and losartan on diabetic nephropathy in a type 2 diabetic rat model
10.4093/dmj.2011.35.2.130
Combined effect of initial and longitudinal increases in γ-glutamyltransferase on incident metabolic syndrome: ARIRANG study
10.3349/ymj.2017.58.4.763
Probucol in albuminuric type 2 diabetes mellitus patients on renin-angiotensin system blockade
10.1161/ATVBAHA.116.308034
Dehydrozingerone exerts beneficial metabolic effects in high-fat diet-induced obese mice via AMPK activation in skeletal muscle
10.1111/jcmm.12455
Peroxisome proliferator-activated receptor δ agonist attenuates hepatic steatosis by anti-inflammatory mechanism
10.3858/emm.2012.44.10.066
Beneficial effects of thiazolidinediones on diabetic nephropathy in OLETF rats
10.3349/ymj.2007.48.2.301
Plasma adiponectin and insulin resistance in Korean type 2 diabetes mellitus
10.3349/ymj.2005.46.1.42
Caffeic acid ameliorates hepatic steatosis and reduces ER stress in high fat diet–induced obese mice by regulating autophagy
10.1016/j.nut.2018.03.010
Aldose reductase inhibitor ameliorates renal vascular endothelial growth factor expression in streptozotocin-induced diabetic rats
10.3349/ymj.2010.51.3.385
Dibenzoylmethane Exerts Metabolic Activity through Regulation of AMP-Activated Protein Kinase (AMPK)-Mediated Glucose Uptake and Adipogenesis Pathways
10.1371/journal.pone.0120104
An unusual case of meningioma showing increased CaSR expression with parathyroid carcinoma
10.3803/EnM.2018.33.1.133
High serum irisin level as an independent predictor of diabetes mellitus: A longitudinal population-based study
10.1097/MD.0000000000003742
A long-standing hyperglycaemic condition impairs skin barrier by accelerating skin ageing process
10.1111/j.1600-0625.2011.01364.x
Short insulin tolerance test can determine the effects of Thiazolidinediones treatment in type 2 diabetes
10.3349/ymj.2008.49.6.901
Antioxidants ameliorate the expression of vascular endothelial growth factor mediated by protein kinase C in diabetic podocytes
10.1093/ndt/gfl022
Optimal waist circumference cutoff values for metabolic syndrome diagnostic criteria in a Korean rural population
10.3346/jkms.2010.25.5.734
High dietary sodium intake assessed by estimated 24-h urinary sodium excretion is associated with NAFLD and hepatic fibrosis
10.1371/journal.pone.0143222
INKT cells prevent obesity-induced hepatic steatosis in mice in a C-C chemokine receptor 7-dependent manner
10.1038/ijo.2017.200
Angiotensin II receptor blocker attenuates overexpression of vascular endothelial growth factor in diabetic podocytes
10.1038/emm.2004.9
Prevalence of metabolic syndrome in type 2 diabetes mellitus using NCEP-ATPIII, IDF and WHO definition and its agreement in Gwalior Chambal region of Central India.
10.5539/gjhs.v5n6p142
Effects of tumor necrosis factor-α on podocyte expression of monocyte chemoattractant protein-1 and in diabetic nephropathy
10.1159/000369576
Effects of ferulic acid on diabetic nephropathy in a rat model of type 2 diabetes
10.3858/emm.2011.43.12.078
Sarpogrelate hydrochloride ameliorates diabetic nephropathy associated with inhibition of macrophage activity and inflammatory reaction in db/db mice
10.1371/journal.pone.0179221
Efficacy and safety of teneligliptin, a dipeptidyl peptidase-4 inhibitor, combined with metformin in Korean patients with type 2 diabetes mellitus: A 16-week, randomized, double-blind, placebo-controlled phase III trial
10.1111/dom.12424
Relationship between γ-glutamyltransferase and metabolic syndrome in a Korean population
10.1111/j.1464-5491.2008.02415.x
Anagliptin and sitagliptin as add-ons to metformin for patients with type 2 diabetes: A 24-week, multicentre, randomized, double-blind, active-controlled, phase III clinical trial with a 28-week extension
10.1111/dom.12429
Role of HbA1c in the screening of diabetes mellitus in a Korean rural community
10.4093/dmj.2012.36.1.37
Erratum to “The association between pentraxin 3 and insulin resistance in obese children at baseline and after physical activity intervention” [Clin. Chim. Acta 413 (2012) 1430–1437] (S000989811200304X) (10.1016/j.cca.2012.06.002))
10.1016/j.cca.2012.06.029
Diabetes epidemics in korea: Reappraise nationwide survey of diabetes "diabetes in korea 2007"
10.4093/dmj.2013.37.4.233
Bone mineral density and bone turnover markers in patients on long-term suppressive levothyroxine therapy for differentiated thyroid cancer
10.4174/astr.2014.86.2.55
Efficacy and safety of lobeglitazone monotherapy in patients with type 2 diabetes mellitus over 24-weeks: A multicenter, randomized, double-blind, parallel-group, placebo controlled trial
10.1371/journal.pone.0092843
Effects of rosiglitazone and metformin on inflammatory markers and adipokines: Decrease in interleukin-18 is an independent factor for the improvement of homeostasis model assessment-beta in type 2 diabetes mellitus
10.1111/j.1365-2265.2006.02723.x
Characteristics of korean patients with primary adrenal insufficiency: A registry-based nationwide survey in Korea
10.3803/EnM.2017.32.4.466
Dual CCR2/5 Antagonist Attenuates Obesity-Induced Insulin Resistance by Regulating Macrophage Recruitment and M1/M2 Status
10.1002/oby.22103
Inverse association between total bilirubin and metabolic syndrome in rural Korean women
10.1089/jwh.2010.2453
Efficacy and safety of teneligliptin, a novel dipeptidyl peptidase-4 inhibitor, in Korean patients with type 2 diabetes mellitus: A 24-week multicentre, randomized, double-blind, placebo-controlled phase III trial
10.1111/dom.12631
Efficacy and safety of adding evogliptin versus sitagliptin for metformin-treated patients with type 2 diabetes: A 24-week randomized, controlled trial with open label extension
10.1111/dom.12870
Taurine alleviates the progression of diabetic nephropathy in type 2 diabetic rat model
10.1155/2014/397307
Serum cystatin C levels are associated with asymptomatic peripheral arterial disease in type 2 diabetes mellitus patients without overt nephropathy
10.1016/j.diabres.2015.02.006
Dibenzoylmethane ameliorates lipid-induced inflammation and oxidative injury in diabetic nephropathy
10.1530/JOE-18-0206
Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db mice
10.1093/ndt/gfs555
Serum adipocyte fatty acid-binding protein levels are associated with nonalcoholic fatty liver disease in type 2 diabetic patients
10.2337/dc08-1379
Adipobiology of diabetes mellitus
10.2174/187152207780363776
Recurrent acute pancreatitis in a patient with type IIb hyperlipoproteinemia: a case report and review of the literature in Korea.
10.3349/ymj.2006.47.1.144
The clustering patterns of metabolic risk factors and its association with sub-clinical atherosclerosis in Korean population
10.3109/03014460.2011.598188
Metabolic changes in urine and serum during progression of diabetic kidney disease in a mouse model
10.1016/j.abb.2018.03.042
Elevated serum γ-glutamyltransferase levels are independently associated with insulin resistance in non-diabetic subjects
10.1016/j.diabres.2009.02.004
Protective effects of curcumin on renal oxidative stress and lipid metabolism in a rat model of type 2 diabetic nephropathy
10.3349/ymj.2016.57.3.664
Obesity is more closely related with hepatic steatosis and fibrosis measured by transient elastography than metabolic health status
10.1016/j.metabol.2016.10.003
Effects of NADPH oxidase inhibitor on diabetic nephropathy in OLETF rats: The role of reducing oxidative stress in its protective property
10.1016/j.diabres.2008.10.007
Anti-diabetic effect of alkaline-reduced water on OLETF rats
10.1271/bbb.70.31
Impaired permeability and antimicrobial barriers in type 2 diabetes skin are linked to increased serum levels of advanced glycation end-product
10.1111/exd.13466
Rice bran protein hydrolysates attenuate diabetic nephropathy in diabetic animal model
10.1007/s00394-016-1366-y
Decreased plasma α-Klotho predict progression of nephropathy with type 2 diabetic patients
10.1016/j.jdiacomp.2016.03.006
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor gemigliptin compared with sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone
10.1111/dom.12060
Efficacy and safety of ipragliflozin as an add-on therapy to sitagliptin and metformin in Korean patients with inadequately controlled type 2 diabetes mellitus: A randomized controlled trial
10.1111/dom.13394
Umbelliferone increases the expression of adipocyte-specific genes in 3 T3-L1 adipocyte
10.1002/ptr.5180
Safety and efficacy of lobeglitazone monotherapy in patients with type 2 diabetes mellitus over 52 weeks: An open-label extension study
10.1016/j.diabres.2015.09.009
Soluble α-klotho as a novel biomarker in the early stage of nephropathy in patients with type 2 diabetes
10.1371/journal.pone.0102984
Efficacy and safety of evogliptin monotherapy in patients with type 2 diabetes and moderately elevated glycated haemoglobin levels after diet and exercise
10.1111/dom.12987
Efficacy and safety of gemigliptin, a dipeptidyl peptidase-4 inhibitor, in patients with type 2 diabetes mellitus inadequately controlled with combination treatment of metformin and sulphonylurea: a 24-week, multicentre, randomized, double-blind, placebo-controlled study (TROICA study)
10.1111/dom.12866
Exposure to pesticides and the prevalence of diabetes in a rural population in Korea
10.1016/j.neuro.2018.10.007
Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress
10.1038/cddis.2015.331
A case of autoimmune hypoglycemia complicated with diabetic ketoacidosis
10.3349/ymj.2004.45.1.140
Lower serum creatinine is associated with low bone mineral density in subjects without overt nephropathy
10.1371/journal.pone.0133062
C-C chemokine receptor 2 inhibitor ameliorates hepatic steatosis by improving er stress and inflammation in a type 2 diabetic mouse model
10.1371/journal.pone.0120711
Oleanolic acid and N-acetylcysteine ameliorate diabetic nephropathy through reduction of oxidative stress and endoplasmic reticulum stress in a type 2 diabetic rat model
10.1093/ndt/gfv377
A randomized, placebo-controlled, double-blind, phase 3 trial to evaluate the efficacy and safety of anagliptin in drug-naïve patients with type 2 diabetes
10.1507/endocrj.EJ14-0544
Immunoglobulin A nephropathy in patients with non-Insulin dependent diabetes mellitus
10.3346/jkms.1999.14.5.582
Reduction in microalbuminuria by calcium channel blockers in patients with type 2 diabetes mellitus and hypertension—A randomized, open-label, active-controlled, superiority, parallel-group clinical trial
10.1111/ijcp.12987
High-dose clevudine impairs mitochondrial function and glucose-stimulated insulin secretion in INS-1E cells
10.1186/1471-230X-12-4
Maternal age at first delivery is associated with the risk of metabolic syndrome in postmenopausal women: From 2008-2010 Korean National Health and Nutrition Examination Survey
10.1371/journal.pone.0127860
RIPK3 Contributes to Lyso-Gb3-Induced Podocyte Death
10.3390/cells10020245
Tetrahydrocurcumin Ameliorates Skin Inflammation by Modulating Autophagy in High-Fat Diet-Induced Obese Mice
10.1155/2021/6621027
Dehydrozingerone inhibits renal lipotoxicity in high‐fat diet–induced obese mice
10.1111/jcmm.16828
Tetrahydrocurcumin Ameliorates Kidney Injury and High Systolic Blood Pressure in High-Fat Diet-Induced Type 2 Diabetic Mice
10.3803/EnM.2021.988
Hyun-Jeong Ko
Ko Hyun-Jeong
ORCID: 0000-0002-3844-928X
Email: hjko@kangwon.ac.kr
Cathelicidin-Related Antimicrobial Peptide Regulates CD73 Expression in Mouse Th17 Cells via p38
10.3390/cells9061561
Lysophosphatidylcholine Enhances Bactericidal Activity by Promoting Phagosome Maturation via the Activation of the NF-κB Pathway during Salmonella Infection in Mouse Macrophages
10.14348/molcells.2020.0030
Local Stabilization of Hypoxia-Inducible Factor-1α Controls Intestinal Inflammation via Enhanced Gut Barrier Function and Immune Regulation.
10.3389/fimmu.2020.609689
GSK3 Restrains Germinal Center B Cells to Form Plasma Cells.
10.4049/jimmunol.2000908
Transcriptome Analysis Illuminates a Hub Role of SREBP2 in Cholesterol Metabolism by α-Mangostin.
10.1021/acsomega.0c04282
Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells.
10.1002/ijc.27974
Inhibition of Experimental Systemic Inflammation (Septic Inflammation) and Chronic Bronchitis by New Phytoformula BL Containing Broussonetia papyrifera and Lonicera japonica.
10.4062/biomolther.2012.081
Insufficient Generation of Mycobactericidal Mediators and Inadequate Level of Phagosomal Maturation Are Related with Susceptibility to Virulent Mycobacterium tuberculosis Infection in Mouse Macrophages.
10.3389/fmicb.2016.00541
Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.
10.1371/journal.pone.0131089
C-C chemokine receptor 2 inhibitor ameliorates hepatic steatosis by improving ER stress and inflammation in a type 2 diabetic mouse model.
10.1371/journal.pone.0120711
Intratumoral injection of attenuated Salmonella vaccine can induce tumor microenvironmental shift from immune suppressive to immunogenic.
10.1016/j.vaccine.2013.01.006
Determination of manassantin B in rat plasma using a high performance liquid chromatography with fluorescence detection and its quantitative application to pharmacokinetic study.
10.1016/j.jchromb.2015.12.058
Complete sequence analysis and antiviral screening of medicinal plants for human coxsackievirus a16 isolated in Korea.
10.1016/j.phrp.2014.12.004
Compensatory roles of CD8+ T cells and plasmacytoid dendritic cells in gut immune regulation for reduced function of CD4+ Tregs.
10.18632/oncotarget.7510
Angelica gigas Nakai and Soluplus-Based Solid Formulations Prepared by Hot-Melting Extrusion: Oral Absorption Enhancing and Memory Ameliorating Effects.
10.1371/journal.pone.0124447
Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells.
10.18632/oncotarget.2589
Interleukin-10 attenuates tumour growth by inhibiting interleukin-6/signal transducer and activator of transcription 3 signalling in myeloid-derived suppressor cells.
10.1016/j.canlet.2016.07.012
A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer.
10.1038/onc.2017.153
Therapeutic and prophylactic activity of itraconazole against human rhinovirus infection in a murine model.
10.1038/srep23110
α-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation.
10.4110/in.2012.12.6.253
Steamed and Fermented Ethanolic Extract from Codonopsis lanceolata Attenuates Amyloid-β-Induced Memory Impairment in Mice.
10.1155/2016/1473801
Cognitive-Enhancing Effect of Steamed and Fermented Codonopsis lanceolata: A Behavioral and Biochemical Study.
10.1155/2014/319436
Pros and cons of VP1-specific maternal IgG for the protection of Enterovirus 71 infection.
10.1016/j.vaccine.2015.10.103
The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma.
10.18632/oncotarget.15326
A Novel Anti-PD-L1 Antibody Exhibits Antitumor Effects on Multiple Myeloma in Murine Models via Antibody-Dependent Cellular Cytotoxicity.
10.4062/biomolther.2020.131
Antiviral Activity of Hederasaponin B from Hedera helix against Enterovirus 71 Subgenotypes C3 and C4a.
10.4062/biomolther.2013.108
Antiviral activity of ginsenosides against coxsackievirus B3, enterovirus 71, and human rhinovirus 3.
10.1016/j.jgr.2014.04.003
iNKT cells prevent obesity-induced hepatic steatosis in mice in a C-C chemokine receptor 7-dependent manner.
10.1038/ijo.2017.200
Dual CCR2/5 Antagonist Attenuates Obesity-Induced Insulin Resistance by Regulating Macrophage Recruitment and M1/M2 Status.
10.1002/oby.22103
Development of intranasal nanovehicles of itraconazole and their immunological activities for the therapy of rhinovirus infection.
10.1016/j.colsurfb.2016.03.050
Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells.
10.18632/oncotarget.17388
Anti-Influenza Activity of Betulinic Acid from Zizyphus jujuba on Influenza A/PR/8 Virus.
10.4062/biomolther.2015.019
Shigella flexneri Inhibits Intestinal Inflammation by Modulation of Host Sphingosine-1-Phosphate in Mice.
10.4110/in.2014.14.2.100
Five new quassinoids and cytotoxic constituents from the roots of Eurycoma longifolia.
10.1016/j.bmcl.2014.06.058
Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice.
10.1038/mi.2016.42
Antiviral Activity of Oroxylin A against Coxsackievirus B3 Alleviates Virus-Induced Acute Pancreatic Damage in Mice.
10.1371/journal.pone.0155784
Antiviral Activity of Chrysin Derivatives against Coxsackievirus B3 in vitro and in vivo.
10.4062/biomolther.2015.095
Therapeutic Potential of the Rhizomes of Anemarrhena asphodeloides and Timosaponin A-III in an Animal Model of Lipopolysaccharide-Induced Lung Inflammation.
10.4062/biomolther.2017.249
Total Synthesis of (+)-Pochonin D and (+)-Monocillin II via Chemo- and Regioselective Intramolecular Nitrile Oxide Cycloaddition.
10.1021/acs.orglett.7b03054
Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression.
10.1038/cmi.2015.73
Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes.
10.1038/s41598-017-06835-3
α-Mangostin ameliorates hepatic steatosis and insulin resistance by inhibition C-C chemokine receptor 2.
10.1371/journal.pone.0179204
Mechanism underlying the suppressor activity of retinoic acid on IL4-induced IgE synthesis and its physiological implication.
10.1016/j.cellimm.2017.10.001
Lysophosphatidylcholine Promotes Phagosome Maturation and Regulates Inflammatory Mediator Production Through the Protein Kinase A-Phosphatidylinositol 3 Kinase-p38 Mitogen-Activated Protein Kinase Signaling Pathway During Mycobacterium tuberculosis Infection in Mouse Macrophages.
10.3389/fimmu.2018.00920
Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production.
10.1038/s41598-017-01462-4
Boronic acid-tethered amphiphilic hyaluronic acid derivative-based nanoassemblies for tumor targeting and penetration.
10.1016/j.actbio.2017.02.030
Inhibitory Effects of Norwogonin, Oroxylin A, and Mosloflavone on Enterovirus 71.
10.4062/biomolther.2015.200
Carbopol-incorporated thermoreversible gel for intranasal drug delivery.
10.3390/molecules20034124
Structural and biochemical characterization of the Bacillus cereus 3-hydroxyisobutyrate dehydrogenase.
10.1016/j.bbrc.2016.04.126
Murine γδ T Cells Render B Cells Refractory to Commitment of IgA Isotype Switching.
10.4110/in.2018.18.e25
Lignan Glycosides and Flavonoid Glycosides from the Aerial Portion of Lespedeza cuneata and Their Biological Evaluations.
10.3390/molecules23081920
Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata.
10.4062/biomolther.2014.019
Tetrameric structure of the flagellar cap protein FliD from Serratia marcescens.
10.1016/j.bbrc.2017.05.093
Antiviral and Anti-Inflammatory Activities of Pochonin D, a Heat Shock Protein 90 Inhibitor, against Rhinovirus Infection.
10.4062/biomolther.2017.233
Antiviral activity of gemcitabine against human rhinovirus in vitro and in vivo.
10.1016/j.antiviral.2017.07.003
Ready-to-use colloidal adjuvant systems for intranasal immunization.
10.1016/j.jcis.2016.01.006
Chemical Identification of Isoflavonoids from a Termite-Associated Streptomyces sp. RB1 and Their Neuroprotective Effects in Murine Hippocampal HT22 Cell Line.
10.3390/ijms19092640
Cycloartane-type triterpenoid derivatives and a flavonoid glycoside from the burs of Castanea crenata.
10.1016/j.phytochem.2018.11.001
Signal transducer and activator of transcription proteins: regulators of myeloid-derived suppressor cell-mediated immunosuppression in cancer.
10.1007/s12272-016-0822-9
A new naphthoquinone analogue and antiviral constituents from the root of Rhinacanthus nasutus.
10.1080/14786419.2018.1452004
Antiviral activity of micafungin against enterovirus 71.
10.1186/s12985-016-0557-8
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network.
10.1038/s41598-018-24935-6
Antiviral and anti-inflammatory activity of budesonide against human rhinovirus infection mediated via autophagy activation.
10.1016/j.antiviral.2018.01.012
Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation.
10.1038/s41598-017-12635-6
Crystal structure of the VanR transcription factor and the role of its unique α-helix in effector recognition.
10.1111/febs.14629
Antiviral Activity of Itraconazole against Echovirus 30 Infection In Vitro.
10.24171/j.phrp.2017.8.5.05
Myeloid-derived suppressor cells in inflammatory bowel disease.
10.5217/ir.2015.13.2.105
Author Correction: Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes.
10.1038/s41598-020-60641-y
Pasakbumin A controls the growth of Mycobacterium tuberculosis by enhancing the autophagy and production of antibacterial mediators in mouse macrophages.
10.1371/journal.pone.0199799
B Cell-Based Vaccine Transduced With ESAT6-Expressing Vaccinia Virus and Presenting α-Galactosylceramide Is a Novel Vaccine Candidate Against ESAT6-Expressing Mycobacterial Diseases.
10.3389/fimmu.2019.02542
Anti-Human Rhinovirus 1B Activity of Dexamethasone viaGCR-Dependent Autophagy Activation.
10.24171/j.phrp.2018.9.6.07
Mercury and arsenic attenuate canonical and non-canonical NLRP3 inflammasome activation.
10.1038/s41598-018-31717-7
CX3CR1+ Macrophages and CD8+ T Cells Control Intestinal IgA Production.
10.4049/jimmunol.1701459
Labdane-type diterpenoids from Vitex limonifolia and their antivirus activities.
10.1007/s11418-017-1125-2
Shigella vaccine development: prospective animal models and current status.
10.2174/1389201014666131226123900
Mucosal dendritic cells shape mucosal immunity.
10.1038/emm.2014.16
Regulation of intestinal immune system by dendritic cells.
10.4110/in.2015.15.1.1
TLR7 Stimulation With Imiquimod Induces Selective Autophagy and Controls Mycobacterium tuberculosis Growth in Mouse Macrophages.
10.3389/fmicb.2020.01684
Esterase-sensitive cleavable histone deacetylase inhibitor-coupled hyaluronic acid nanoparticles for boosting anticancer activities against lung adenocarcinoma.
10.1039/c9bm00895k
Morin Hydrate Inhibits Influenza Virus entry into Host Cells and Has Anti-inflammatory Effect in Influenza-infected Mice.
10.4110/in.2020.20.e32
Crystal structure of FlgL and its implications for flagellar assembly.
10.1038/s41598-018-32460-9
Manassantin B shows antiviral activity against coxsackievirus B3 infection by activation of the STING/TBK-1/IRF3 signalling pathway.
10.1038/s41598-019-45868-8
The Intestinal Epithelium: Central Coordinator of Mucosal Immunity.
10.1016/j.it.2018.04.002
AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy.
10.1038/nature18014
Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.
10.1016/j.celrep.2019.05.020
Enteric Viruses Ameliorate Gut Inflammation via Toll-like Receptor 3 and Toll-like Receptor 7-Mediated Interferon-β Production.
10.1016/j.immuni.2016.03.009
Development of New Preventive and Therapeutic Vaccines for Tuberculosis.
10.4110/in.2018.18.e17
Chemical components from the twigs of Caesalpinia latisiliqua and their antiviral activity.
10.1007/s11418-019-01335-2
IκBζ controls NLRP3 inflammasome activation via upregulation of the Nlrp3 gene.
10.1016/j.cyto.2019.154983
IκBζ facilitates protective immunity against Salmonella infection via Th1 differentiation and IgG production.
10.1038/s41598-019-44019-3
Plasmacytoid dendritic cells regulate colitis-associated tumorigenesis by controlling myeloid-derived suppressor cell infiltration.
10.1016/j.canlet.2020.08.007